neostigmine has been researched along with Congenital Myasthenia in 7 studies
Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Congenital myasthenic syndromes are a group of genetic neuromuscular disorders caused by mutations that impair synaptic transmission at the neuromuscular junction." | 1.62 | Administration of Sugammadex Intraoperatively in a Patient With a Congenital Myasthenic Syndrome: A Case Report. ( Mukkamala, SG; Pappy, AL; Sirmon, CAF, 2021) |
| "Congenital myasthenia gravis is caused by genetic mutations affecting neuromuscular transmission, characterized by muscle weakness usually starting in childhood." | 1.39 | Congenital myasthenia gravis. ( Memon, MN; Nizamani, NB; Talpur, KI, 2013) |
| "The authors describe two patients with congenital myasthenic syndrome (CMS) with end plate acetylcholinesterase (AChE) deficiency caused by mutations in the collagenic tail (ColQ) of AChE: a homozygous C-terminal Y230S mutation in Patient 1 and Y430S and a C-terminal splice-site mutation in Patient 2." | 1.33 | Congenital endplate acetylcholinesterase deficiency responsive to ephedrine. ( Bestue-Cardiel, M; Capablo-Liesa, JL; Engel, AG; López-Pisón, J; Martin-Martinez, J; Peña-Segura, JL; Sáenz de Cabezón-Alvarez, A, 2005) |
| "The first pregnancy was complicated during the 3rd trimester by a hydramnion." | 1.31 | [Transient neonatal myasthenia gravis]. ( Göhring, UJ; Haupt, WF; Herkenrath, P; Kribs, A; Licht, C; Michalk, DV; Model, P; Roth, B, 2002) |
| "This congenital myasthenic syndrome is for the first time associated with an autosomal translocation 2q31-9p27." | 1.31 | [Slow channel syndrome due to an autosomal translocation at 2q31-9p27]. ( Crielaard, JM; Hansen, I; Wang, FC; Zeevaert, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Pappy, AL | 1 |
| Sirmon, CAF | 1 |
| Mukkamala, SG | 1 |
| Maselli, RA | 1 |
| Arredondo, J | 1 |
| Nguyen, J | 1 |
| Lara, M | 1 |
| Ng, F | 1 |
| Ngo, M | 1 |
| Pham, JM | 1 |
| Yi, Q | 1 |
| Stajich, JM | 1 |
| McDonald, K | 1 |
| Hauser, MA | 1 |
| Wollmann, RL | 1 |
| Nizamani, NB | 1 |
| Talpur, KI | 1 |
| Memon, MN | 1 |
| Zhu, H | 1 |
| Bhattacharyya, BJ | 1 |
| Lin, H | 1 |
| Gomez, CM | 1 |
| Licht, C | 1 |
| Model, P | 1 |
| Kribs, A | 1 |
| Herkenrath, P | 1 |
| Michalk, DV | 1 |
| Haupt, WF | 1 |
| Göhring, UJ | 1 |
| Roth, B | 1 |
| Bestue-Cardiel, M | 1 |
| Sáenz de Cabezón-Alvarez, A | 1 |
| Capablo-Liesa, JL | 1 |
| López-Pisón, J | 1 |
| Peña-Segura, JL | 1 |
| Martin-Martinez, J | 1 |
| Engel, AG | 1 |
| Zeevaert, B | 1 |
| Hansen, I | 1 |
| Crielaard, JM | 1 |
| Wang, FC | 1 |
7 other studies available for neostigmine and Congenital Myasthenia
| Article | Year |
|---|---|
Administration of Sugammadex Intraoperatively in a Patient With a Congenital Myasthenic Syndrome: A Case Report.
Topics: Child; gamma-Cyclodextrins; Humans; Male; Myasthenic Syndromes, Congenital; Neostigmine; Neuromuscul | 2021 |
Exome sequencing detection of two untranslated GFPT1 mutations in a family with limb-girdle myasthenia.
Topics: 4-Aminopyridine; Aged; Amifampridine; Base Sequence; DNA Mutational Analysis; Electromyography; Exom | 2014 |
Congenital myasthenia gravis.
Topics: Child, Preschool; Cholinesterase Inhibitors; Humans; Male; Myasthenic Syndromes, Congenital; Neostig | 2013 |
Skeletal muscle IP3R1 receptors amplify physiological and pathological synaptic calcium signals.
Topics: Action Potentials; Animals; Boron Compounds; Calcium; Calcium Signaling; Calpain; Carbachol; Caspase | 2011 |
[Transient neonatal myasthenia gravis].
Topics: Adult; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Infant, Newborn; Intensive Care | 2002 |
Congenital endplate acetylcholinesterase deficiency responsive to ephedrine.
Topics: Acetylcholinesterase; Adolescent; Adrenergic Agents; Child; Cholinesterase Inhibitors; Diagnosis, Di | 2005 |
[Slow channel syndrome due to an autosomal translocation at 2q31-9p27].
Topics: Action Potentials; Adult; Autoimmune Diseases; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair | 2002 |