verapamil has been researched along with Congenital Myasthenia in 1 studies
Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In slow-channel congenital myasthenic syndrome, point mutations of the endplate acetylcholine receptor (AChR) prolong channel openings, leading to excessive Ca(2+) entry with ensuing endplate degeneration and myasthenic symptoms." | 1.37 | Modulation of the Ca(2+) permeability of human endplate acetylcholine receptor-channel. ( Bigi, R; Deflorio, C; Fucile, S; Grassi, F; Piccari, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piccari, V | 1 |
| Deflorio, C | 1 |
| Bigi, R | 1 |
| Grassi, F | 1 |
| Fucile, S | 1 |
1 other study available for verapamil and Congenital Myasthenia
| Article | Year |
|---|---|
Modulation of the Ca(2+) permeability of human endplate acetylcholine receptor-channel.
Topics: Albuterol; Amino Acid Substitution; Animals; Apoptosis; Calcium; Cell Line; Humans; Motor Endplate; | 2011 |