Page last updated: 2024-09-28

Creeping Eruption

Infections caused by nematode larvae which never develop into the adult stage and migrate through various body tissues. They commonly infect the skin, eyes, and viscera in man. Ancylostoma brasiliensis causes cutaneous larva migrans. Toxocara causes visceral larva migrans.

Synonyms(8)

Synonym
Creeping Eruption
Dew Itch
Ground Itch
Cutaneous Larva Migrans
Larva Migrans
Larva Migrans, Cutaneous
Larva Migrans, Ocular
Ocular Larva Migrans

Research Excerpts

Overview

ExcerptReference
"Cutaneous larva migrans is becoming more common in the U."( Harman, RR; Jones, SK; Oliwiecki, S; Reynolds, NJ, 1990)
"A case of buccal larva migrans is presented."( Achten, G; André, J; Bernard, M; Ledoux, M, 1988)
"Cutaneous larva migrans is a distinctive dermatitis caused by the filariform larvae of certain nematode parasites."( Borak, J; Herbener, D, 1988)
"Cutaneous larva migrans is frequently seen in the southern United States, Central and South America, and other subtropical areas but rarely in northern climates."( Douglass, MC; Edelglass, JW; Stiefler, R; Tessler, M, 1982)
"Creeping eruptions are caused by the presence of larvae of certain nematodes in human skin."( Stingl, P, 1982)
"Larva migrans is a rare cutaneous parasitic infestation, whose incidence in Israel has increased over the past few years."( Friedman, J; Gold, I; Shelkovitz-Shiloh, I; Stempler, D; Tal, O; Trau, H, 1993)
"Cutaneous larva migrans is an infection with a larval nematode, most frequently by dog or cat hookworms."( Davies, HD; Keystone, JS; Sakuls, P, 1993)
"Cutaneous larva migrans is considered to be a self-limited parasitic infection of about 2 to 8 weeks' duration, though it has been reported to persist for as long as 55 weeks."( Fitzpatrick, JE; Gentry, RH; Morgan, AM; Richey, TK, 1996)
"Cutaneous larva migrans is rarely contracted in temperate countries."( Combemale, P; Dupin, M; Le Coz, C; Piens, MA; Zimmermann, R, 1995)
"Cutaneous larva migrans is the result of infestation of human skin by helminth larvae, which burrow through the epidermis."( Mattone-Volpe, F, 1998)
"Cutaneous larva migrans is a tropical disease that typically is acquired on exposed surfaces in patients who have been sitting or lying on moist ground or other surfaces which have been contaminated by dog or cat feces."( Sugathan, P, 2002)
"Cutaneous larva migrans is occasionally seen in pediatric emergency outpatient care settings."( Simon, MW; Simon, NP, 2003)
"A case of cutaneous larva migrans is presented."( Chambers, S; Manning, L; Maurice, P; Paltridge, G, 2006)
"Larva migrans is a condition caused by subcutaneous or visceral migration of parasite larvae, usually Ancylostoma braziliense, and is characterized by pruriginous or serpiginous lesions."( Aburad de Carvalhosa, A; Catanhede Orsini Machado de Sousa, S; dos Santos Pinto Júnior, D; Thomé Capuano, AC, 2006)
"Infection with cutaneous larva migrans is one of the most common "souvenirs" from the tropics."( Groffik, A; Hengge, UR; Hoff, NP; Mota, R, 2008)
"Cutaneous larva migrans is a parasitic disease caused by Ancylostoma braziliense and Ancylostoma caninum larvae, which is transmitted by contact with sand infested with these parasites."( Calderón, M; García-Fernández, L, 2014)
"The hookworm related Cutaneous Larva Migrans is a common disease present in the tropic and subtropical areas of the world."( Quashie, NB; Tsegah, E, 2015)
"Cutaneous larva migrans is one of the most common skin diseases reported in travelers returning from tropical regions."( Barankin, B; Hon, KLE; Leung, AKC, 2017)
"Cutaneous larva migrans is a zoonotic infestation caused by penetration and migration in the epidermis of filariform larva of different kinds of animal hookworms through contact with feces of infected animals."( Barankin, B; Hon, KLE; Leung, AKC, 2017)
"Cutaneous larva migrans is a frequent dermatologic problem among travelers in tropical areas, but its association with Löffler's syndrome is an extremely rare condition, particularly in children."( Li, LF; Wang, S; Xu, W, 2017)
"Cutaneous larva migrans is a neglected zoonotic helminthic disease which is paradoxically underreported in low-income and middle-income countries from where a majority of the cases emanate."( Agbor, VN; Dimala, CA; Kadia, BM; Tianyi, FL, 2018)
"Cutaneous larva migrans is an endemic disease with predilection for poor and vulnerable persons."( Agbor, VN; Dimala, CA; Kadia, BM; Tianyi, FL, 2018)
"Cutaneous larva migrans is a dermatitis, typically acquired in warm tropical or sub-tropical countries, caused by migration of the larvae of nematodes (hookworm; mainly Ancylostoma braziliense and, occasionally, Ancylostoma caninum or Uncinaria stenocephala), which are parasitic on animals such as cats and dogs, into the patient's skin."( Del Giudice, P; Hakimi, S; Hubiche, T; Magana, C; Vandenbos, F, 2019)

Context

ExcerptReference
"Although cutaneous larva migrans has traditionally been considered a tropical disease, clinicians should be cognizant of its expanding geographic spread."( Bae, GH; Cheema, KS; Johanis, M; Narala, S; Novoa, RA; Saleem, A; Young, PA, 2023)

Treatment

ExcerptReference
"The case of cutaneous larva migrans presented here is typical for its mechanism and geographic location of infection, evolution of lesions, and prompt response to treatment."( Jones, WB, 1993)
"The treatment of cutaneous larva migrans and Toxocara infection relies on antihelminthic agents such as thiabendazole, albendazole and ivermectin."( Caumes, E, 2003)
"When a patient is diagnosed as having larva migrans syndrome, oral-administration of albendazole is recommended, however, the regimen remains controversial worldwide."( Hombu, A; Kikuchi, T; Kuroki, M; Maruyama, H; Nagayasu, E; Yoshida, A, 2019)

Research

Studies (307)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990115 (37.46)23.3326
1990's42 (13.68)12.5806
2000's68 (22.15)18.1394
2010's70 (22.80)28.8240
2020's12 (3.91)9.53
DrugIndicatedRelationship StrengthStudiesTrials
ethylene chlorohydrin0low10
hydrochloric acid0low10
salicylic acid0low10
dimethyl sulfoxide0medium42
histamine0low10
iodine0low10
4-aminobenzoic acid0low10
uric acid0low10
albendazole0medium963
aspirin0low10
chlorpheniramine0low10
cimetidine0low10
ddt0low20
diethylcarbamazine0low110
fenthion0low10
hexylresorcinol0low10
hydroxychloroquine0low10
mebendazole0low100
niclosamide0low10
praziquantel0low10
promethazine0low20
thiabendazole0medium1133
benzimidazole0low10
trichlorfon0low30
prednisone0low30
chloramphenicol0low10
cloxacillin0low10
ethyl chloride0low40
methylprednisolone0low20
thiazoles0low10
betamethasone0low10
emetine0low10
dithiazanine0low10
gentian violet0low10
phosmet0low10
gadolinium0low10
trolamine salicylate0low10
parbendazole0low10
levamisole0low10
tetradecanoylphorbol acetate0low10
tetrachloroethylene0low10
flubendazole0low20
methylprednisolone aceponate0low10
albendazole sulfoxide0low10
nsc-1727550low10
foxes0low10
levalbuterol0low10
atropine0low10
tretinoin0low10
mupirocin0low10
clindamycin0low10
thiourea0low10
pica0low10
pulmicort0low10
phenylephrine hydrochloride0low10
clobetasol0low10
antimony0low30
amoxicillin-potassium clavulanate combination0low10
dextrothyroxine0medium532
ants0low10
oxytetracycline, anhydrous0low10
budesonide, formoterol fumarate drug combination0low10
agar0low10
bassianolide0low10
hyaluronoglucosaminidase0low10
moxidectin0low10
selamectin0low10
exudates0low30
avermectin0low10
eye0low70

Protein Targets (693)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE140014
Genome polyprotein 0011
USP1 protein, partial7007
AR protein280028
thyroid stimulating hormone receptor140014
glucocorticoid receptor [Homo sapiens]190019
retinoic acid nuclear receptor alpha variant 1250025
estrogen nuclear receptor alpha280028
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a150015
Histone H2A.x7007
chromobox protein homolog 17007
transcriptional regulator ERG isoform 33003
geminin210021
Polyphenol oxidase 20304
Cellular tumor antigen p53170017
Thiopurine S-methyltransferase0101
Succinate-semialdehyde dehydrogenase, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
Cytochrome P450 1B10101
Dihydropteroate synthase 0011
Chain A, Beta-lactamase8008
Luciferase100010
glp-1 receptor, partial4004
hypoxia-inducible factor 1 alpha subunit100010
RAR-related orphan receptor gamma200020
ATAD5 protein, partial4004
Fumarate hydratase6006
TDP1 protein190019
GLI family zinc finger 3220022
caspase 7, apoptosis-related cysteine protease4004
nuclear receptor subfamily 1, group I, member 3150015
progesterone receptor170017
retinoid X nuclear receptor alpha200020
estrogen-related nuclear receptor alpha250025
farnesoid X nuclear receptor140014
pregnane X nuclear receptor230023
polyprotein6006
67.9K protein3003
peroxisome proliferator activated receptor gamma160016
vitamin D (1,25- dihydroxyvitamin D3) receptor170017
caspase-34004
IDH17007
euchromatic histone-lysine N-methyltransferase 2170017
aryl hydrocarbon receptor180018
v-jun sarcoma virus 17 oncogene homolog (avian)140014
nuclear receptor subfamily 1, group I, member 29009
cellular tumor antigen p53 isoform a7007
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
nuclear factor erythroid 2-related factor 2 isoform 25005
thyroid hormone receptor beta isoform 2170017
histone deacetylase 9 isoform 38008
heat shock protein beta-18008
mitogen-activated protein kinase 17007
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Vif0001
peripheral myelin protein 22120012
survival motor neuron protein isoform d9009
muscleblind-like protein 1 isoform 15005
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
lamin isoform A-delta10130013
neuropeptide S receptor isoform A3003
ATP-binding cassette sub-family C member 3016016
Multidrug resistance-associated protein 4016016
Voltage-dependent calcium channel gamma-2 subunit140014
Bile salt export pump022022
Interferon beta180018
Integrin beta-35106
Integrin alpha-IIb5106
Methionine aminopeptidase0303
Glutamate receptor 2140014
Fatty-acid amide hydrolase 11304
Inositol monophosphatase 14004
Canalicular multispecific organic anion transporter 1015015
ATPase family AAA domain-containing protein 5100010
Ataxin-2130013
cytochrome P450 family 3 subfamily A polypeptide 4190019
EWS/FLI fusion protein100010
cytochrome P450 2D6150015
nuclear factor erythroid 2-related factor 2 isoform 1220022
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, 2-oxoglutarate Oxygenase8008
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 84004
thioredoxin reductase140014
GLS protein6006
aldehyde dehydrogenase 1 family, member A1120012
hypothetical protein, conserved2002
glucocerebrosidase5005
peroxisome proliferator-activated receptor delta110011
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 17007
DNA polymerase iota isoform a (long)7007
DNA polymerase kappa isoform 17007
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)8008
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60404
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0303
Carbonic anhydrase 10506
Carbonic anhydrase 20507
Fatty acid-binding protein, liver0101
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10102
Adenosine receptor A2a0102
Substance-P receptor0101
Prostaglandin G/H synthase 20303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma7119
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-191010
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10415
Sigma non-opioid intracellular receptor 10011
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta3003
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0406
5-hydroxytryptamine receptor 40404
Muscarinic acetylcholine receptor M209113
Muscarinic acetylcholine receptor M408111
Muscarinic acetylcholine receptor M10215
Muscarinic acetylcholine receptor M30215
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M508111
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M108112
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M308111
Alpha-1D adrenergic receptor0808
5-hydroxytryptamine receptor 2C0404
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor3228
5-hydroxytryptamine receptor 70202
Reverse transcriptase/RNaseH 0102
Muscarinic acetylcholine receptor0112
Chain A, GTPase KRas, isoform 2B0011
Chain A, GTPase KRas, isoform 2B0011
Membrane primary amine oxidase 0101
Cytochrome P450 2B10102
Cytochrome P450 1A10102
GTPase KRas0011
Polyunsaturated fatty acid 5-lipoxygenase0001
Glutaminyl-peptide cyclotransferase0202
Lanosterol 14-alpha demethylase0101
Membrane primary amine oxidase0101
Glutaminyl-peptide cyclotransferase0101
pregnane X receptor6006
thyroid hormone receptor beta isoform a8008
galanin receptor type 30101
Glucocorticoid receptor08210
Glycine receptor subunit alpha-10808
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
ORF730011
G120012
activating transcription factor 6100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
streptokinase A precursor0022
Dihydroxyacetone phosphate acyltransferase0001
HLA class I histocompatibility antigen, B alpha chain 120012
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Cytochrome P450 3A40415
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Inositol hexakisphosphate kinase 1120012
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial120012
PPM1D protein7007
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0202
Spike glycoprotein0347
Replicase polyprotein 1ab0347
glucose-6-phosphate 1-dehydrogenase isoform b0202
flap endonuclease 16006
Transmembrane protease serine 20347
Dihydrofolate reductase 0101
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0022
Amyloid-beta precursor protein0202
Histidine-rich protein PFHRP-II0102
Procathepsin L0347
Alpha-2A adrenergic receptor0808
Replicase polyprotein 1a0347
Replicase polyprotein 1ab0347
Replicase polyprotein 1ab0448
Spike glycoprotein0101
Replicase polyprotein 1ab0448
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0606
Alpha-2C adrenergic receptor0808
DNA ligase 10101
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Spike glycoprotein73414
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20404
Sigma intracellular receptor 20202
Phosphoethanolamine N-methyltransferase0101
Angiotensin-converting enzyme 2 0347
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
arylsulfatase A4004
atrial natriuretic peptide receptor 1 precursor3003
atrial natriuretic peptide receptor 2 precursor2002
Histamine H1 receptor0628
MBT domain-containing protein 10101
Solute carrier family 22 member 10405
Lethal(3)malignant brain tumor-like protein 40101
Lethal(3)malignant brain tumor-like protein 30101
Chloroquine resistance transporter0202
Solute carrier family 22 member 20405
Lethal(3)malignant brain tumor-like protein 10101
ATP-dependent phosphofructokinase100010
phosphopantetheinyl transferase7007
alpha-galactosidase1001
cytochrome P450 2C19 precursor3003
cytochrome P450 3A4 isoform 19009
M-phase phosphoprotein 86006
Solute carrier family 22 member 10101
Gamma-aminobutyric acid receptor subunit pi9009
Solute carrier family 22 member 20204
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10203
Cytochrome P450 2D60213
Cytochrome P450 2C9 0213
Gamma-aminobutyric acid receptor subunit beta-19009
Gamma-aminobutyric acid receptor subunit delta9009
Gamma-aminobutyric acid receptor subunit gamma-29009
Gamma-aminobutyric acid receptor subunit alpha-59009
Gamma-aminobutyric acid receptor subunit alpha-39009
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10101
Gamma-aminobutyric acid receptor subunit gamma-19009
Gamma-aminobutyric acid receptor subunit alpha-29009
Histamine H2 receptor0729
Gamma-aminobutyric acid receptor subunit alpha-49009
Gamma-aminobutyric acid receptor subunit gamma-39009
Gamma-aminobutyric acid receptor subunit alpha-69009
Histamine H1 receptor0134
Potassium-transporting ATPase subunit beta0101
Cytochrome P450 2J20101
Gamma-aminobutyric acid receptor subunit beta-39009
Gamma-aminobutyric acid receptor subunit beta-29009
Aldehyde oxidase0101
Solute carrier family 22 member 60203
Multidrug and toxin extrusion protein 20101
Solute carrier family 22 member 80405
GABA theta subunit9009
Multidrug and toxin extrusion protein 10202
Gamma-aminobutyric acid receptor subunit epsilon9009
Histamine H4 receptor0224
Solute carrier family 22 member 110101
Solute carrier family 22 member 40101
Solute carrier family 22 member 80202
Protein-arginine deiminase type-40101
Beta-lactamase 0101
Bile salt export pump0303
Solute carrier family 22 member 80101
Beta-lactamase OXA-70001
Solute carrier family 15 member 10101
Beta-lactamase TEM0101
Solute carrier family 15 member 20101
Efflux transporter 0101
Beta-lactamase 0101
Solute carrier family 15 member 20101
Metallo-b-lactamase 0001
Beta-lactamase class B VIM-2 0001
Chain A, Cruzipain5005
SMAD family member 27007
SMAD family member 37007
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)130013
estrogen receptor 2 (ER beta)130013
thyroid stimulating hormone receptor6006
Caspase-73003
potassium voltage-gated channel subfamily H member 2 isoform d6006
caspase-33003
nuclear factor NF-kappa-B p105 subunit isoform 12002
Androgen receptor0707
Chain A, Ferritin light chain6006
endonuclease IV2002
Microtubule-associated protein tau8009
nonstructural protein 15005
peripheral myelin protein 22 isoform 12002
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
NS5 0011
Parkin3003
NPC intracellular cholesterol transporter 1 precursor3003
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 13003
Glucose transporter0101
Serine hydrolase RBBP90101
Hexose transporter 1 0101
Solute carrier family 2, facilitated glucose transporter member 10101
Hypoxia-inducible factor 1-alpha0102
Dihydroorotate dehydrogenase 0101
Endothelial PAS domain-containing protein 10102
Chain A, JmjC domain-containing histone demethylation protein 3A3003
acetylcholinesterase7007
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
Guanine nucleotide-binding protein G2002
relaxin receptor 1 isoform 11001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
luciferase1001
thyrotropin-releasing hormone receptor2002
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
vitamin D3 receptor isoform VDRA7007
huntingtin isoform 25005
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
nuclear receptor ROR-gamma isoform 17007
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Tyrosine-protein kinase Fyn0101
60 kDa chaperonin0202
Adenosine receptor A30404
60 kDa heat shock protein, mitochondrial0202
D(2) dopamine receptor0404
Alpha-1B adrenergic receptor0404
Substance-K receptor0202
D(1A) dopamine receptor0404
Acetylcholinesterase0202
Glutamate receptor ionotropic, kainate 11001
5-hydroxytryptamine receptor 2A0404
Adenosine receptor A2a0202
Mu-type opioid receptor0202
D(3) dopamine receptor0404
Kappa-type opioid receptor0202
Glutamate receptor ionotropic, kainate 21001
Glutamate receptor ionotropic, kainate 31001
Alpha-1A adrenergic receptor0404
10 kDa heat shock protein, mitochondrial0202
Disintegrin and metalloproteinase domain-containing protein 172002
Glutamate receptor ionotropic, kainate 41001
Sodium-dependent dopamine transporter 0202
Leukotriene B4 receptor 11001
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
Glutamate receptor ionotropic, kainate 51001
10 kDa chaperonin 0202
Leukotriene B4 receptor 21001
15-lipoxygenase, partial2002
GALC protein6006
bromodomain adjacent to zinc finger domain 2B5005
Polyunsaturated fatty acid 5-lipoxygenase0101
Tyrosinase0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Polyunsaturated fatty acid lipoxygenase ALOX120101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
apical membrane antigen 1, AMA12002
regulator of G-protein signaling 47007
transforming acidic coiled-coil-containing protein 30001
Carbonic anhydrase 120102
Solute carrier family 22 member 30102
Plasma kallikrein0001
Carbonic anhydrase 30102
Macrophage migration inhibitory factor0202
Carbonic anhydrase 40203
Carbonic anhydrase 60203
5-hydroxytryptamine receptor 1D0001
Histamine H1 receptor0213
Metabotropic glutamate receptor 50112
Carbonic anhydrase 5A, mitochondrial0203
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0102
Carbonic anhydrase 70203
Carbonic anhydrase0002
Histamine H3 receptor0101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Histamine N-methyltransferase 0101
Carbonic anhydrase 90203
Carbonic anhydrase 0002
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0103
Carbonic anhydrase0002
Glutamate receptor ionotropic, NMDA 2D0001
Carbonic anhydrase 0002
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3B0001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40001
Carbonic anhydrase 150102
Carbonic anhydrase 130203
Histamine H3 receptor0101
Carboxylic ester hydrolase 0001
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0203
Histamine H3 receptor0123
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Genome polyprotein 0101
Cyclic GMP-AMP synthase0101
Toll-like receptor 90101
Toll-like receptor 70101
NFKB1 protein, partial2002
cytochrome P450 2D6 isoform 14004
Beta-2 adrenergic receptor0112
dopamine D1 receptor1001
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0101
cytochrome P450 2C9 precursor2002
Tyrosine-protein kinase ABL10303
Proto-oncogene tyrosine-protein kinase Src0303
Vascular endothelial growth factor receptor 20202
Calmodulin-domain protein kinase 10101
Nuclear receptor subfamily 1 group I member 20011
Nuclear receptor subfamily 1 group I member 20011
Chain A, Isoleucyl-tRNA synthetase0101
heat shock protein 900011
twin arginine protein translocation system - TatA protein0001
Isoleucine--tRNA ligase0101
Estrogen receptor0011
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase0101
TAR DNA-binding protein 432002
Estrogen receptor beta0011
TSHR protein1001
Thrombopoietin2002
PINK11001
pyruvate kinase2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
D(1A) dopamine receptor2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
pyruvate kinase PKM isoform b1001
Aurora kinase A0101
3-phosphoinositide-dependent protein kinase 10101
Tyrosine-protein kinase JAK20101
Tyrosine-protein kinase Lyn0101
Ornithine decarboxylase1002
Platelet-derived growth factor receptor beta0101
Mast/stem cell growth factor receptor Kit0101
Fibroblast growth factor receptor 10101
Serine/threonine-protein kinase B-raf0101
Protein kinase C alpha type0213
Mitogen-activated protein kinase 10202
RAC-alpha serine/threonine-protein kinase0101
Receptor-type tyrosine-protein kinase FLT30101
Alpha-synuclein1102
Signal transducer and activator of transcription 30101
Mitogen-activated protein kinase 80101
Glycogen synthase kinase-3 beta0101
D(1A) dopamine receptor2002
Angiopoietin-1 receptor0101
Anoctamin-10101
Rap guanine nucleotide exchange factor 41001
WRN1001
Valosin-containing protein0101
thioredoxin glutathione reductase3003
lysosomal alpha-glucosidase preproprotein2002
microphthalmia-associated transcription factor isoform 90101
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase PLK12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
eukaryotic translation initiation factor 4E isoform 10101
histone acetyltransferase KAT2A isoform 14004
Rap guanine nucleotide exchange factor 31001
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Serum paraoxonase/arylesterase 10101
phosphoglycerate kinase1001
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0011
Snq2p0001
Aldo-keto reductase family 1 member B10202
Calmodulin-10101
5-hydroxytryptamine receptor 1A0404
Sodium-dependent noradrenaline transporter 0202
5-hydroxytryptamine receptor 1B0202
Trypanothione reductase0202
Sodium-dependent serotonin transporter0202
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60202
Calmodulin 0011
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Estrogen receptor0101
Interleukin-50101
Interleukin-50101
Progesterone receptor0101
Glucocorticoid receptor0101
Mineralocorticoid receptor 0112
Matrix metalloproteinase-90101
Interleukin-5 receptor subunit alpha0101
Sodium-dependent serotonin transporter0101
Estrogen receptor beta0101
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Albumin0101
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Beta-1 adrenergic receptor0101
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Chain A, Methionine aminopeptidase0101
BRCA11001
P531001
Cytochrome P450 1A20112
Endothelin receptor type B1001
Endothelin-1 receptor1001
Methionine aminopeptidase 20101
Methionine aminopeptidase 10112
Peptidyl-prolyl cis-trans isomerase FKBP1A0011
isocitrate dehydrogenase 1, partial1001
serine-protein kinase ATM isoform a1001
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
Urease0203
5-hydroxytryptamine receptor 2A0101
Urease subunit alpha0101
D(3) dopamine receptor0101
Urease subunit alpha0101
Urease subunit beta0101
Urease subunit beta 0101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Chain A, Nuclear Receptor ROR-beta0101
Ornithine decarboxylase0001
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Alpha-1D adrenergic receptor0101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2C190011
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]