Page last updated: 2024-09-28

Dwarfism, Thanatophoric

A severe form of neonatal dwarfism with very short limbs. All cases have died at birth or later in the neonatal period.

Synonyms(4)

Synonym
Thanatophoric Dwarfism
Thanatophoric Dysplasia
Dwarfism, Thanatophoric
Thanatophoric Short Stature

Research Excerpts

Overview

ExcerptReference
"Thanatophoric dwarfism is not as rare as once thought."( Meehan, FP; Rafla, NM, 1991)
"Thanatophoric dwarfism is a lethal bone dysplasia causing severe disturbance in body proportions, shortening and deformation of the long bones and maldevelopment of the chest leading to severe respiratory failure and early death."( Kruczek, A; Kruczek, P; Mitkowska, Z; Pietrzyk, JJ, 2002)

Treatment

ExcerptReference
"Using a mouse model of Thanatophoric Dysplasia Type II (TDII) we show that both HDAC6 deletion and treatment with the small molecule HDAC6 inhibitor tubacin reduced FGFR3 accumulation in the growth plate and improved endochondral bone growth."( Hurlin, PJ; Ota, S; Romero, MP; Yang, G; Zhou, ZQ, 2016)

Research

Studies (32)

TimeframeStudies, This Condition (%)All Conditions %
pre-19903 (9.38)23.3326
1990's14 (43.75)12.5806
2000's9 (28.13)18.1394
2010's6 (18.75)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
thymine0low10
phenytoin0low10
amitriptyline0low10
hydroxyurea0low10
phenobarbital0low10
potassium chloride0low10
lysine0low10
tyrosine0low40
methionine0low10
cytidine0low10
arginine0low30
fluorobenzenes0low10
mannose0low10
phosphotyrosine0low10
lovastatin0low10
zileuton0low10
masoprocol0low10
paxilline0low10
bradykinin0low10
cystine0low10
calcitriol0low10
phenylephrine hydrochloride0low10
brefeldin a0low20
cysteine0low80
tubacin0low10
staurosporine0low10
midostaurin0low10
natriuretic peptide, c-type0low10
heparitin sulfate0low10
transforming growth factor beta0low10
muramidase0low10

Protein Targets (953)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
thioredoxin reductase8008
USP1 protein, partial5005
NFKB1 protein, partial4004
GLS protein5005
cytochrome P450 family 3 subfamily A polypeptide 43003
cytochrome P450 2D62002
arylsulfatase A3003
cytochrome P450 2D6 isoform 12002
D(1A) dopamine receptor2002
chromobox protein homolog 18008
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 12002
nuclear factor erythroid 2-related factor 2 isoform 15005
muscarinic acetylcholine receptor M14004
Solute carrier family 22 member 1 0101
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40505
Voltage-dependent L-type calcium channel subunit alpha-1F0202
5-hydroxytryptamine receptor 40202
Bile salt export pump0707
Albumin0011
High affinity nerve growth factor receptor0134
Aldo-keto reductase family 1 member B10404
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
5-hydroxytryptamine receptor 2C0101
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10202
Angiotensin-converting enzyme0202
D(2) dopamine receptor0202
5-hydroxytryptamine receptor 2A0101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
5-hydroxytryptamine receptor 1A0303
Muscarinic acetylcholine receptor M30202
D(1A) dopamine receptor0202
D(1B) dopamine receptor0101
UDP-glucuronosyltransferase 1A40001
Sodium-dependent noradrenaline transporter 0415
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0202
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0101
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Histamine H1 receptor0202
D(3) dopamine receptor0202
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 4 subunit alpha0203
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0101
Histamine H2 receptor3105
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
5-hydroxytryptamine receptor 70101
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Sodium-dependent dopamine transporter 0404
Potassium voltage-gated channel subfamily H member 20404
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0202
Sigma non-opioid intracellular receptor 10011
5-hydroxytryptamine receptor 4 0101
Nuclear receptor subfamily 3 group C member 3 0202
Canalicular multispecific organic anion transporter 10505
Sodium channel protein type 2 subunit alpha0303
Ataxin-22002
Sigma non-opioid intracellular receptor 10202
5-hydroxytryptamine receptor 3B0101
Sodium channel protein type 3 subunit alpha0303
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase2002
thyroid stimulating hormone receptor3003
alpha-galactosidase2002
euchromatic histone-lysine N-methyltransferase 29009
cytochrome P450 2C19 precursor2002
flap endonuclease 13003
DNA polymerase iota isoform a (long)2002
lethal factor (plasmid)2002
Cytochrome P450 3A40204
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
ATP-dependent phosphofructokinase2002
histone acetyltransferase KAT2A isoform 13003
Angiotensin-converting enzyme 0001
B2 bradykinin receptor0101
B2 bradykinin receptor0215
B1 bradykinin receptor0101
Olfactory receptor 51E20011
PAX80001
ATAD5 protein, partial2002
TDP1 protein6006
thioredoxin glutathione reductase3003
Smad34004
67.9K protein2002
IDH14004
NPC intracellular cholesterol transporter 1 precursor1001
major prion protein preproprotein Prp precursor0101
nuclear receptor subfamily 0 group B member 10101
thyroid hormone receptor beta isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 22002
ras-related protein Rab-9A2002
steroidogenic factor 10101
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
geminin9009
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase3003
Chain A, Ferritin light chain3003
Vitamin D3 receptor0011
PPM1D protein2002
Microtubule-associated protein tau4004
mitogen-activated protein kinase 12002
nuclear receptor ROR-gamma isoform 13003
peripheral myelin protein 222002
Interferon beta4004
Vitamin D-binding protein0011
Cytochrome P450 1A20102
Androgen receptor0101
Cytochrome P450 2D60101
Vitamin D3 receptor0124
Cytochrome P450 2C9 0203
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0011
Cytochrome P450 2C190101
Kappa-type opioid receptor0011
Vitamin D3 receptor0011
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
EWS/FLI fusion protein6006
Glucose transporter0101
Cdk-related protein kinase 60101
Protein kinase domain-containing protein0101
Hexose transporter 1 0101
Solute carrier family 2, facilitated glucose transporter member 10101
Deoxycytidine kinase0012
Cytidine deaminase0001
Spike glycoprotein4004
Calcium-dependent protein kinase 10112
Mitogen-activated protein kinase 0101
Proline--tRNA ligase0101
Calcium-dependent protein kinase 40101
Lysine--tRNA ligase 0101
Uridine-cytidine kinase 1 0001
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
Histone H2A.x2002
acetylcholinesterase2002
Fumarate hydratase3003
AR protein6006
retinoic acid nuclear receptor alpha variant 13003
pregnane X nuclear receptor4004
estrogen nuclear receptor alpha8008
polyprotein3003
Bloom syndrome protein isoform 14004
peripheral myelin protein 22 isoform 13003
vitamin D3 receptor isoform VDRA3003
cytochrome P450 3A4 isoform 13003
lamin isoform A-delta106006
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit pi3104
Gamma-aminobutyric acid receptor subunit delta0202
Carbonic anhydrase 20406
Stromelysin-10022
Gamma-aminobutyric acid receptor subunit alpha-10202
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-13104
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit delta3104
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit gamma-23104
Gamma-aminobutyric acid receptor subunit alpha-53104
Gamma-aminobutyric acid receptor subunit alpha-33104
Carbonic anhydrase 40304
Gamma-aminobutyric acid receptor subunit gamma-13104
Gamma-aminobutyric acid receptor subunit alpha-23104
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit alpha-43104
Gamma-aminobutyric acid receptor subunit beta-30202
Gamma-aminobutyric acid receptor subunit gamma-33104
Gamma-aminobutyric acid receptor subunit alpha-63104
Gamma-aminobutyric acid receptor subunit alpha-50202
Gamma-aminobutyric acid receptor subunit alpha-30202
Carbonic anhydrase 5A, mitochondrial0304
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit alpha-13104
Gamma-aminobutyric acid receptor subunit beta-33104
Gamma-aminobutyric acid receptor subunit beta-23104
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0202
Inositol monophosphatase 13003
Gamma-aminobutyric acid receptor subunit alpha-60202
Carbonic anhydrase 90305
Gamma-aminobutyric acid receptor subunit gamma-10202
GABA theta subunit3104
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit epsilon3104
Gamma-aminobutyric acid receptor subunit theta0202
Chain A, Antigen Cd11a (p180)0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, 2-oxoglutarate Oxygenase4004
Chain A, Cruzipain1001
15-lipoxygenase, partial2002
pregnane X receptor1001
hypoxia-inducible factor 1 alpha subunit1001
RAR-related orphan receptor gamma2002
SMAD family member 21001
SMAD family member 31001
GLI family zinc finger 34004
caspase 7, apoptosis-related cysteine protease1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
PINK11001
estrogen receptor 2 (ER beta)1001
nuclear receptor subfamily 1, group I, member 33003
progesterone receptor1001
isocitrate dehydrogenase 1, partial1001
glucocorticoid receptor [Homo sapiens]3003
retinoid X nuclear receptor alpha2002
estrogen-related nuclear receptor alpha5005
farnesoid X nuclear receptor1001
Parkin2002
peroxisome proliferator-activated receptor delta1001
peroxisome proliferator activated receptor gamma4004
caspase-31001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
activating transcription factor 61001
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)1001
nuclear receptor subfamily 1, group I, member 21001
potassium voltage-gated channel subfamily H member 2 isoform d4004
thyroid hormone receptor beta isoform 22002
heat shock protein beta-11001
bcl-2-related protein A10101
survival motor neuron protein isoform d2002
Voltage-dependent calcium channel gamma-2 subunit1001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Cellular tumor antigen p532002
Integrin beta-20101
Intercellular adhesion molecule 10101
ATP-dependent translocase ABCB10101
Neutrophil elastase0101
Insulin receptor 0101
Androgen receptor0202
Glutamate receptor 21001
Integrin alpha-L0112
Substance-K receptor0202
Adenosine receptor A10202
Prostaglandin G/H synthase 20415
Nuclear receptor ROR-gamma1001
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Histone deacetylase 10314
Lanosterol 14-alpha demethylase0101
Rap guanine nucleotide exchange factor 41001
Histone deacetylase 20303
Acyl-CoA:cholesterol acyltransferase 0202
Histone deacetylase 60314
Solute carrier organic anion transporter family member 1B10101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0202
transcriptional regulator ERG isoform 32002
DNA polymerase kappa isoform 12002
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
ClpP1001
Thrombopoietin1001
DNA polymerase III, partial1001
aldehyde dehydrogenase 1 family, member A13003
hypothetical protein, conserved1001
regulator of G-protein signaling 42002
nonstructural protein 11001
aryl hydrocarbon receptor2002
hexokinase-4 isoform 11001
cellular tumor antigen p53 isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
cytochrome P450 2C9 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
glucokinase regulatory protein1001
DNA polymerase beta1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
M-phase phosphoprotein 81001
Integrin beta-31001
Prostaglandin G/H synthase 10202
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb1001
Alpha-synuclein1001
Disintegrin and metalloproteinase domain-containing protein 171001
Single-stranded DNA cytosine deaminase1001
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Large neutral amino acids transporter small subunit 10202
Leukotriene C4 synthase0011
tyrosine-protein kinase Yes1001
Bone morphogenetic protein receptor type-1B0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0011
Serine/threonine-protein kinase PLK40011
Serine/threonine-protein kinase 250011
ATP-dependent RNA helicase DDX3X0011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase RIO30011
Dual specificity mitogen-activated protein kinase kinase 70011
Serine/threonine-protein kinase Chk10011
Inhibitor of nuclear factor kappa-B kinase subunit beta0012
Peripheral plasma membrane protein CASK0011
Aurora kinase A0112
Cyclin-G-associated kinase0011
Serine/threonine-protein kinase DCLK10011
Inhibitor of nuclear factor kappa-B kinase subunit alpha0011
Muscle, skeletal receptor tyrosine-protein kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Mitogen-activated protein kinase 130011
3-phosphoinositide-dependent protein kinase 10011
Mitogen-activated protein kinase kinase kinase 130011
Death-associated protein kinase 30011
Mitogen-activated protein kinase kinase kinase 70011
Receptor-interacting serine/threonine-protein kinase 20011
NUAK family SNF1-like kinase 10011
Dynamin-like 120 kDa protein, mitochondrial0011
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0011
Serine/threonine-protein kinase PAK 30011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 17B0011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Cyclin-dependent kinase 140011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Serine/threonine-protein kinase OSR10011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Serine/threonine-protein kinase Chk20011
Tyrosine-protein kinase ABL10112
Epidermal growth factor receptor0011
RAF proto-oncogene serine/threonine-protein kinase0011
Receptor tyrosine-protein kinase erbB-20011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0012
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0112
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Proto-oncogene tyrosine-protein kinase ROS0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Wee1-like protein kinase 20011
Uncharacterized serine/threonine-protein kinase SBK30011
Serine/threonine-protein kinase A-Raf0011
Mast/stem cell growth factor receptor Kit0112
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0112
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Myosin light chain kinase, smooth muscle0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0012
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Insulin receptor-related protein0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Platelet-derived growth factor receptor alpha0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
Vascular endothelial growth factor receptor 1 0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Interferon-induced, double-stranded RNA-activated protein kinase0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Serine/threonine-protein kinase MAK0011
Cyclin-dependent kinase 11B0011
Ephrin type-A receptor 10011
Fibroblast growth factor receptor 20011
Receptor tyrosine-protein kinase erbB-30011
Multifunctional protein ADE20011
Fibroblast growth factor receptor 40011
Fibroblast growth factor receptor 30011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Protein kinase C eta type0011
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Activin receptor type-2A0011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-A receptor 30011
Ephrin type-A receptor 80011
Ephrin type-B receptor 20011
Leukocyte tyrosine kinase receptor0011
Non-receptor tyrosine-protein kinase TYK20011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
Tyrosine-protein kinase receptor UFO0011
Mitogen-activated protein kinase 40011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
G protein-coupled receptor kinase 40011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Tyrosine-protein kinase receptor Tie-10011
Vascular endothelial growth factor receptor 30011
Vascular endothelial growth factor receptor 20112
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30213
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0011
Serine/threonine-protein kinase mTOR0011
Megakaryocyte-associated tyrosine-protein kinase0011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase TXK0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
Tyrosine-protein kinase ZAP-700011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0011
MAP kinase-activated protein kinase 20011
Cyclin-dependent kinase 80011
Elongation factor Tu, mitochondrial0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Tyrosine-protein kinase Blk0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0011
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Serine/threonine-protein kinase Nek40011
Tyrosine-protein kinase JAK30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
Death-associated protein kinase 10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 120011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10012
5'-AMP-activated protein kinase catalytic subunit alpha-20012
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-B receptor 10011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Hormonally up-regulated neu tumor-associated kinase0011
Serine/threonine-protein kinase SIK10011
Receptor-interacting serine/threonine-protein kinase 40011
Ras-related protein Rab-100011
Cell division control protein 2 homolog0011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Tubulin alpha-1A chain0011
Casein kinase II subunit alpha0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0011
SRSF protein kinase 20011
Casein kinase I isoform gamma-20011
Mitogen-activated protein kinase kinase kinase 90011
Protein delta homolog 10011
Serine/threonine-protein kinase PknB0011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase-like 10011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Protein kinase C epsilon type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Angiopoietin-1 receptor0011
Mitogen-activated protein kinase kinase kinase 100011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Tyrosine-protein kinase receptor TYRO30011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0011
Myotonin-protein kinase0011
Aspartyl/asparaginyl beta-hydroxylase0202
Mitogen-activated protein kinase kinase kinase kinase 20011
Mitogen-activated protein kinase kinase kinase 120011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Serine/threonine-protein kinase PAK 10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
cGMP-dependent protein kinase 20011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase PRP4 homolog0011
Receptor-interacting serine/threonine-protein kinase 10011
Calcium/calmodulin-dependent protein kinase type II subunit beta0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Calcium/calmodulin-dependent protein kinase type 10011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Serine/threonine-protein kinase D10011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40011
Ribosomal protein S6 kinase alpha-20011
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Rhodopsin kinase GRK10011
NT-3 growth factor receptor0011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
BDNF/NT-3 growth factors receptor0011
Mitogen-activated protein kinase 60011
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10112
Myosin light chain kinase 30011
Serine/threonine-protein kinase SBK10011
Mitogen-activated protein kinase kinase kinase 190011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase TNNI3K0011
Rab-like protein 30011
Leucine-rich repeat serine/threonine-protein kinase 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Serine/threonine-protein kinase Nek50011
Serine/threonine-protein kinase ULK30011
Dual serine/threonine and tyrosine protein kinase0011
Mitogen-activated protein kinase kinase kinase 150011
Uncharacterized protein FLJ452520011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Serine/threonine-protein kinase tousled-like 20011
Serine/threonine-protein kinase 32C0011
Serine/threonine-protein kinase pim-30011
Serine/threonine-protein kinase VRK20011
Myosin light chain kinase family member 40011
Homeodomain-interacting protein kinase 10011
Calcium/calmodulin-dependent protein kinase type 1D0011
Mitogen-activated protein kinase kinase kinase kinase 30011
Cyclin-dependent kinase-like 30011
MAP kinase-activated protein kinase 50011
Serine/threonine-protein kinase BRSK20011
Serine/threonine-protein kinase NIM10011
Serine/threonine-protein kinase ULK20011
Misshapen-like kinase 10011
Serine/threonine-protein kinase DCLK20011
Calcium/calmodulin-dependent protein kinase kinase 10011
Casein kinase I isoform alpha-like0011
Homeodomain-interacting protein kinase 40011
Myosin-IIIa0011
Ankyrin repeat and protein kinase domain-containing protein 10011
Serine/threonine-protein kinase Nek110011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase BRSK10011
Serine/threonine-protein kinase 350011
Serine/threonine-protein kinase Nek70011
Rhodopsin kinase GRK70011
Serine/threonine-protein kinase 32A0011
Myosin-IIIb0011
ATP-dependent RNA helicase DDX10011
Dual specificity tyrosine-phosphorylation-regulated kinase 20011
Cyclin-dependent kinase-like 20011
Mitogen-activated protein kinase kinase kinase kinase 10011
Serine/threonine-protein kinase Sgk30011
Atypical kinase COQ8B, mitochondrial0011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
Cyclin-dependent kinase 150011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
SRSF protein kinase 10011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Serine/threonine-protein kinase RIO10011
MAP kinase-interacting serine/threonine-protein kinase 10011
Serine/threonine-protein kinase RIO20011
Cyclin-dependent kinase 190011
Transient receptor potential cation channel subfamily M member 60011
Testis-specific serine/threonine-protein kinase 10011
Serine/threonine-protein kinase 330011
Serine/threonine-protein kinase D20011
Serine/threonine-protein kinase DCLK30011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
Myosin light chain kinase 2, skeletal/cardiac muscle0011
STE20-like serine/threonine-protein kinase 0011
Poly [ADP-ribose] polymerase tankyrase-20011
Serine/threonine-protein kinase TAO30011
Homeodomain-interacting protein kinase 20011
Tyrosine-protein kinase Srms0011
Homeodomain-interacting protein kinase 30011
Serine/threonine-protein kinase PLK30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
MAP kinase-interacting serine/threonine-protein kinase 20011
Serine/threonine-protein kinase Nek60011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
SNF-related serine/threonine-protein kinase0011
Serine/threonine-protein kinase LATS20011
Serine/threonine-protein kinase 360011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Serine/threonine-protein kinase 32B0011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase PLK20011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase MARK10011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase PAK 50011
Serine/threonine-protein kinase 260011
eIF-2-alpha kinase GCN20011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Phosphatidylinositol 4-kinase beta0011
Serine/threonine-protein kinase 17A0011
STE20/SPS1-related proline-alanine-rich protein kinase0011
Ephrin type-A receptor 60011
5'-AMP-activated protein kinase subunit gamma-20012
Serine/threonine-protein kinase TBK10011
Septin-90011
Death-associated protein kinase 20011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase tousled-like 10011
Serine/threonine-protein kinase TAO20011
ALK tyrosine kinase receptor0011
SRSF protein kinase 30011
Serine/threonine-protein kinase ICK0011
Cyclin-dependent kinase 11A0011
Aurora kinase C0011
Calcium/calmodulin-dependent protein kinase type II subunit alpha0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase 38-like0011
Microtubule-associated serine/threonine-protein kinase 10011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Chain A, JmjC domain-containing histone demethylation protein 3A1001
glp-1 receptor, partial2002
bromodomain adjacent to zinc finger domain 2B1001
TPA: protein transporter TIM100101
huntingtin isoform 21001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
tumor susceptibility gene 101 protein1001
POsterior Segregation0011
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
neuropeptide S receptor isoform A1001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20101
TAR DNA-binding protein 431001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30101
Zinc finger protein mex-50011
BZLF20101
GALC protein2002
thyroid stimulating hormone receptor1001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein2002
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Gamma-aminobutyric acid 0101
endonuclease IV1001
G2002
atrial natriuretic peptide receptor 1 precursor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Dihydrofolate reductase 0101
HLA class I histocompatibility antigen, B alpha chain 2002
Sodium channel protein type 2 subunit alpha0101
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Inositol hexakisphosphate kinase 12002
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
cytochrome P450 2C9, partial2002
Growth factor receptor-bound protein 20001
Tyrosine-protein phosphatase non-receptor type 110001
Carbonic anhydrase 10304
Taste receptor type 2 member 310011
Taste receptor type 2 member 600011
Sodium/potassium/calcium exchanger 40112
Taste receptor type 2 member 140012
Taste receptor type 2 member 130011
Taste receptor type 2 member 90011
Taste receptor type 2 member 40011
Sodium/potassium/calcium exchanger 20112
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20103
Carbonic anhydrase 120102
5'-AMP-activated protein kinase subunit beta-20001
Bile salt export pump0202
Albumin0101
Polymerase acidic protein0011
Carbonic anhydrase 30102
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Prostaglandin G/H synthase 10202
Carbonic anhydrase 60102
Cystathionine gamma-lyase0101
Carbonic anhydrase 70102
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150102
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
5'-AMP-activated protein kinase subunit beta-10001
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
Thymidine phosphorylase0101
Histone deacetylase 30202
Leukotriene A-4 hydrolase0202
Histone deacetylase 40202
Histone deacetylase 70202
HD2 type histone deacetylase HDA106 0101
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
Histone deacetylase 90202
Histone deacetylase 50202
Nuclear receptor corepressor 20101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Plasma kallikrein0001
Adenosine receptor A10001
Adenosine receptor A2a0001
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Glutamate receptor ionotropic, NMDA 3A0001
Prostaglandin E synthase0101
Tumor necrosis factor ligand superfamily member 110101
Prostaglandin G/H synthase 1 0001
Prostaglandin G/H synthase 2 0001
Polyunsaturated fatty acid 5-lipoxygenase0112
Polyunsaturated fatty acid 5-lipoxygenase0103
Polyunsaturated fatty acid lipoxygenase ALOX150101
Polyunsaturated fatty acid lipoxygenase ALOX120101
Arachidonate 5-lipoxygenase-activating protein0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0001
Polyunsaturated fatty acid 5-lipoxygenase0101
Thromboxane-A synthase0101
Leukotriene B4 receptor 10112
Prostaglandin G/H synthase 1 0001
Leukotriene B4 receptor 20011
Cysteinyl leukotriene receptor 20101
Cysteinyl leukotriene receptor 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]