Night Terrors

A disorder characterized by incomplete arousals from sleep associated with behavior suggesting extreme fright. This condition primarily affects children and young adults and the individual generally has no recall of the event. Episodes tend to occur during stage III or IV. SOMNAMBULISM is frequently associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p391)

Synonyms(10)

Synonym
Sleep Terrors
Night Terrors, Adult
Sleep Terror Disorder
Pavor Nocturnus, Childhood
Night Terrors
Night Terrors, Primary
Night Terrors, Secondary
Pavor Nocturnus
Pavor Nocturnus, Adult
Night Terrors, Childhood

Research Excerpts

Overview

Excerpt	Reference
"Sleep terrors are a type of sleep disorder that is classified as parasomnias and is more common in children than in adults."	( Aziz, SG; Hussain, S, 2021)

Research

Studies (33)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	1 (3.03)	12.5806
2000's	13 (39.39)	18.1394
2010's	18 (54.55)	28.8240
2020's	1 (3.03)	9.53

Drug	Relationship Strength	Studies	Trials
5-hydroxytryptophan	medium	1	1
salicylic acid	low	1	0
creatine	low	1	0
melatonin	medium	3	1
niacinamide	low	1	0
3,4-methylenedioxyamphetamine	low	1	0
cetirizine	low	1	0
clonazepam	low	1	0
clonidine	low	3	0
valproic acid	low	1	0
donepezil	low	1	0
fluoxetine	low	2	0
ketamine	low	1	0
lamotrigine	low	1	0
methylphenidate	low	1	0
mianserin	low	1	0
midazolam	low	1	0
mirtazapine	low	1	0
modafinil	low	1	0
piracetam	low	1	0
prazosin	low	3	0
propofol	low	1	0
triazolam	medium	1	1
zolpidem	medium	2	1
aspartic acid	low	1	0
cyclohexanol	low	1	0
pyrroles	low	1	0
thiazoles	low	1	0
s,n,n'-tripropylthiocarbamate	low	1	0
trolamine salicylate	low	1	0
timolol	low	1	0
atorvastatin	low	1	0
venlafaxine hydrochloride	low	1	0
n-acetylaspartic acid	low	1	0
niaprazine	low	1	0
pramipexole	low	1	0
ramelteon	low	1	0
abacavir	low	1	0
levetiracetam	low	1	0
piperidines	low	1	0

Protein Targets (553)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
5-hydroxytryptamine receptor 2C	0	10	1	11
5-hydroxytryptamine receptor 2A	0	9	1	10
5-hydroxytryptamine receptor 1A	0	11	2	13
Sodium-dependent noradrenaline transporter	0	12	1	13
Sodium-dependent dopamine transporter	0	7	2	9
5-hydroxytryptamine receptor 1B	0	9	1	10
5-hydroxytryptamine receptor 1D	0	3	1	4
5-hydroxytryptamine receptor 1F	0	3	1	4
5-hydroxytryptamine receptor 2B	0	8	1	9
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	16	3	19
Sodium-dependent serotonin transporter	0	7	1	8
5-hydroxytryptamine receptor 7	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	2	1	3
Sodium-dependent dopamine transporter	0	11	1	12
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	2	1	3
Luciferase	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
cytochrome P450 2D6	10	0	0	10
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
peripheral myelin protein 22	7	0	0	7
Albumin	0	1	2	3
ATP-dependent translocase ABCB1	0	5	0	7
Replicase polyprotein 1ab	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Reverse transcriptase/RNaseH	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Ferritin light chain	3	0	0	3
phosphopantetheinyl transferase	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	5	0	0	5
arylsulfatase A	5	0	0	5
Bloom syndrome protein isoform 1	5	0	0	5
cytochrome P450 2C19 precursor	4	0	0	4
lethal factor (plasmid)	2	0	0	2
lamin isoform A-delta10	12	0	0	12
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	3	0	4
Carbonic anhydrase 2	0	3	0	4
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	3	0	4
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Chain A, Cruzipain	2	0	0	2
RAR-related orphan receptor gamma	6	0	0	6
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
GLI family zinc finger 3	11	0	0	11
AR protein	10	0	0	10
caspase 7, apoptosis-related cysteine protease	4	0	0	4
estrogen receptor 2 (ER beta)	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	10	0	0	10
glucocorticoid receptor [Homo sapiens]	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	9	0	0	9
retinoid X nuclear receptor alpha	8	0	0	8
estrogen-related nuclear receptor alpha	11	0	0	11
pregnane X nuclear receptor	12	0	0	12
estrogen nuclear receptor alpha	14	0	0	14
peroxisome proliferator-activated receptor delta	3	0	0	3
peroxisome proliferator activated receptor gamma	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
caspase-3	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	8	0	0	8
Caspase-7	3	0	0	3
vitamin D3 receptor isoform VDRA	2	0	0	2
thyroid hormone receptor beta isoform a	4	0	0	4
caspase-3	3	0	0	3
thyroid hormone receptor beta isoform 2	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	4	0	0	4
geminin	16	0	0	16
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Solute carrier organic anion transporter family member 2B1	0	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Cellular tumor antigen p53	10	0	0	10
Insulin receptor	0	1	0	1
Glutamate receptor 2	3	0	0	3
Dipeptidyl peptidase 4	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Histone deacetylase 1	0	3	0	3
Histone deacetylase 2	0	3	0	3
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Histone deacetylase 6	0	3	0	3
Solute carrier organic anion transporter family member 1B1	0	1	0	2
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Histamine H1 receptor	0	6	1	7
Angiopoietin-1 receptor	0	0	1	1
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Multidrug and toxin extrusion protein 1	0	4	0	4
Histamine H4 receptor	0	2	1	3
ATP-dependent phosphofructokinase	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit pi	5	6	2	13
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	3	9
Gamma-aminobutyric acid receptor subunit beta-1	5	6	2	13
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit delta	5	6	2	13
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	2	8
Gamma-aminobutyric acid receptor subunit gamma-2	5	6	2	13
Gamma-aminobutyric acid receptor subunit alpha-5	5	6	2	13
Gamma-aminobutyric acid receptor subunit alpha-3	5	6	2	13
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	5	6	2	13
Gamma-aminobutyric acid receptor subunit alpha-2	5	6	2	13
Gamma-aminobutyric acid receptor subunit alpha-4	5	6	2	13
Gamma-aminobutyric acid receptor subunit beta-3	0	6	1	7
Gamma-aminobutyric acid receptor subunit gamma-3	5	6	2	13
Gamma-aminobutyric acid receptor subunit alpha-6	5	6	2	13
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	5	3	8
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	2	7
Gamma-aminobutyric acid receptor subunit beta-2	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-1	5	6	2	13
Gamma-aminobutyric acid receptor subunit beta-3	5	6	2	13
Gamma-aminobutyric acid receptor subunit beta-2	5	6	2	13
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	5	1	6
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
GABA theta subunit	5	6	2	13
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	5	6	2	13
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
acetylcholinesterase	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
regulator of G-protein signaling 4	5	0	0	5
Beta-1 adrenergic receptor	0	0	2	2
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2D6 isoform 1	7	0	0	7
cytochrome P450 2C9 precursor	3	0	0	3
muscarinic acetylcholine receptor M1	7	0	0	7
Membrane primary amine oxidase	0	1	0	1
Solute carrier family 22 member 1	0	5	0	6
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	3	0	3
5-hydroxytryptamine receptor 1A	0	7	4	11
Alpha-2A adrenergic receptor	0	13	1	15
Alpha-1B adrenergic receptor	0	11	2	13
Alpha-2B adrenergic receptor	0	13	1	15
Alpha-1A adrenergic receptor	0	2	1	3
Alpha-2C adrenergic receptor	0	12	1	14
D	0	6	0	6
D(3) dopamine receptor	0	4	1	5
Alpha-2B adrenergic receptor	0	8	2	10
Amine oxidase [flavin-containing] A	0	2	0	2
Alpha-2C adrenergic receptor	0	8	2	10
Alpha-2A adrenergic receptor	0	8	2	10
Alpha-1D adrenergic receptor	0	11	2	13
Alpha-1D adrenergic receptor	0	10	2	15
D(1B) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Adenosine receptor A2b	0	0	1	1
Adenosine receptor A2a	0	0	1	1
Alpha-2B adrenergic receptor	0	1	0	2
D(4) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	9	2	16
Alpha-1B adrenergic receptor	0	5	2	10
Alpha-1A adrenergic receptor	0	13	4	17
Histamine H2 receptor	3	1	0	5
5-hydroxytryptamine receptor 7	0	2	0	2
Spike glycoprotein	8	0	0	8
D(2) dopamine receptor	0	10	1	11
Mu-type opioid receptor	0	1	0	1
Inositol monophosphatase 1	3	0	0	3
Alpha-2C adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	1	0	2
Nischarin	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
aryl hydrocarbon receptor	6	0	0	6
thyroid stimulating hormone receptor	5	0	0	5
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D6	0	5	0	6
Muscarinic acetylcholine receptor M2	0	1	0	1
Cytochrome P450 2C9	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2J2	0	2	0	2
Taste receptor type 2 member 46	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	6	0	6
Cytochrome P450 2D4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	3	0	3
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
endonuclease IV	1	0	0	1
thioredoxin reductase	10	0	0	10
TDP1 protein	10	0	0	10
thyroid stimulating hormone receptor	2	0	0	2
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
peripheral myelin protein 22 isoform 1	4	0	0	4
chromobox protein homolog 1	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
mitogen-activated protein kinase 1	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
survival motor neuron protein isoform d	3	0	0	3
Alpha-synuclein	2	0	0	2
TAR DNA-binding protein 43	2	0	0	2
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	12
Acetylcholinesterase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Bile salt export pump	0	3	0	3
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Bile salt export pump	0	17	0	17
Acetylcholinesterase	0	1	0	1
Amyloid-beta precursor protein	0	1	0	1
Cholinesterase	0	3	0	3
Cytochrome P450 3A4	0	4	0	4
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	5	2	7
Liver carboxylesterase 1	0	2	0	2
Acetylcholinesterase	0	3	0	3
Choline O-acetyltransferase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Beta-secretase 1	0	1	0	1
Cholinesterase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Cholinesterase	0	1	0	1
Acetylcholine receptor subunit epsilon	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Cytochrome P450 1B1	0	3	0	3
Canalicular multispecific organic anion transporter 1	0	11	0	11
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Carboxylic ester hydrolase	0	3	0	3
Histamine H3 receptor	0	4	0	4
ATAD5 protein, partial	5	0	0	5
USP1 protein, partial	3	0	0	3
EWS/FLI fusion protein	9	0	0	9
IDH1	1	0	0	1
D(1A) dopamine receptor	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
Alpha-1A adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 4	0	10	0	10
Interstitial collagenase	0	2	0	2
Beta-2 adrenergic receptor	0	5	0	5
Angiotensin-converting enzyme	0	8	0	8
5-hydroxytryptamine receptor 2C	0	11	0	11
5-hydroxytryptamine receptor 2B	0	10	0	10
D(1A) dopamine receptor	3	0	0	3
Nuclear receptor subfamily 3 group C member 3	0	8	0	8
progesterone receptor	3	0	0	3
G	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
Histone H2A.x	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
huntingtin isoform 2	2	0	0	2
ras-related protein Rab-9A	4	0	0	4
Sodium-dependent noradrenaline transporter	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Interferon beta	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Albumin	0	0	2	2
Aldo-keto reductase family 1 member B1	0	7	0	7
Muscarinic acetylcholine receptor M5	0	5	0	5
Cytochrome P450 2C8	0	1	0	1
Muscarinic acetylcholine receptor M1	0	6	0	6
Dipeptidyl peptidase 4	0	1	0	1
Muscarinic acetylcholine receptor M3	0	7	0	7
Prostaglandin G/H synthase 1	0	3	0	3
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
5-hydroxytryptamine receptor 2A	0	7	1	8
Cytochrome P450 2C19	0	2	0	2
5-hydroxytryptamine receptor 6	0	6	0	7
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	3	0	3
Beta-2 adrenergic receptor	0	1	1	2
Inositol hexakisphosphate kinase 1	2	0	0	2
Ataxin-2	7	0	0	7
Transporter	0	8	0	8
cytochrome P450 2C9, partial	2	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
GALC protein	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
flap endonuclease 1	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	2	0	2
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
interleukin 8	1	0	0	1
ClpP	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
cytochrome P450 3A4 isoform 1	5	0	0	5
M-phase phosphoprotein 8	2	0	0	2
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Myeloperoxidase	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Aromatase	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	0	3
Metabotropic glutamate receptor 1	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	3	1	4
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	3	1	4
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Nuclear receptor ROR-gamma	2	0	0	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Fumarate hydratase	2	0	0	2
GLS protein	4	0	0	4
polyprotein	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	1	0	1
D(2) dopamine receptor	0	8	2	10
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	5	1	6
D(4) dopamine receptor	0	6	1	7
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	5	2	7
Endothelin-1 receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	5	0	5
Type-2 angiotensin II receptor	0	3	0	3
D(3) dopamine receptor	0	8	2	11
5-hydroxytryptamine receptor 3A	0	3	0	3
Angiotensin-converting enzyme	0	2	0	2
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
G-protein coupled receptor	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Translocator protein	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1-6	0	1	0	2
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
glp-1 receptor, partial	1	0	0	1
thioredoxin glutathione reductase	1	0	0	1
67.9K protein	2	0	0	2
transcriptional regulator ERG isoform 3	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase kappa isoform 1	1	0	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
farnesoid X nuclear receptor	5	0	0	5
activating transcription factor 6	2	0	0	2
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	2	0	2
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
ATPase family AAA domain-containing protein 5	5	0	0	5
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
Chain A, Beta-lactamase	1	0	0	1
Hsf1 protein	0	0	1	2
Guanine nucleotide-binding protein G	1	0	0	1
Beta-3 adrenergic receptor	0	3	0	3
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	0	2
5-hydroxytryptamine receptor 1E	0	1	0	1
Delta-type opioid receptor	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
D	0	1	0	1
Solute carrier family 22 member 2	0	0	0	1
Microtubule-associated protein tau	1	0	0	1
glucocerebrosidase	1	0	0	1
alpha-galactosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
interferon gamma precursor	0	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
nuclear receptor ROR-gamma isoform 1	2	0	0	2
Solute carrier family 22 member 2	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Beta-casein	0	1	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Matrix metalloproteinase-9	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
heat shock protein beta-1	1	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Smad3	1	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
Glycine receptor subunit alpha-1	0	0	1	1
Histamine H1 receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Polyphenol oxidase 2	0	1	0	2
Carbonic anhydrase 12	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
NFKB1 protein, partial	1	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
pregnane X receptor	1	0	0	1
Cocaine esterase	0	1	0	1
Histone deacetylase 3	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

chemdatabank.com