Page last updated: 2024-09-27

Bone Marrow Failure

Synonyms(3)

Synonym
Bone Marrow Failure Syndromes
Bone Marrow Failure
Bone Marrow Failure Syndrome

Research Excerpts

Overview

ExcerptReference
"Osteoporosis and bone marrow failure are additional unexplained complications in HIV-positive patients and patients with AIDS, respectively."( Gauss, K; Meissner, N; Ran, Y; Searles, S; Taylor, D; Wilkison, M, 2012)
"Bone marrow failure syndromes are characterized by ineffective hematopoiesis due to impaired fitness of hematopoietic stem cells."( Bartram, J; Filippi, MD; Hinge, A; Javier, J; Xu, J, 2022)

Context

ExcerptReference
"Bone marrow failure has many different etiologies, including genetic defects which manifest with specific syndromes, as well as acquired conditions as a result of insults to the bone marrow leading to aplasia."( Fassel, H; Sheth, S, 2020)

Treatment

ExcerptReference
"The treatment approach for bone marrow failure is very dependent on the underlying cause, which makes it all the more critical to have an accurate diagnosis."( Fassel, H; Sheth, S, 2020)

Research

Studies (63)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's39 (61.90)28.8240
2020's24 (38.10)9.53
DrugIndicatedRelationship StrengthStudiesTrials
benzene0low10
formaldehyde0low10
uric acid0low10
xanthine0low10
azathioprine0low10
busulfan0low10
deferiprone0low10
fluorouracil0low20
hydroxyurea0low10
midazolam0low10
activins0low10
phenobarbital0low10
temozolomide0low10
mitomycin0low20
oxandrolone0medium11
dehydroepiandrosterone0low10
methylprednisolone0low10
hydrazine0low20
azacitidine0low10
malondialdehyde0low10
diepoxybutane0low10
acetylcysteine0low10
ethylnitrosourea0low10
cladribine0low10
vidarabine0medium41
levamisole0low10
danazol0low20
adenosine0low10
plerixafor0low10
methotrexate0low10
irofulven0low10
epiglucan0low10
prostaglandin h20low10
tacrolimus0low10
mycophenolic acid0medium31
riboflavin0low10
isomethyleugenol0low10
fludarabine0medium41
sesquiterpenes0low10
methyl-thiohydantoin-tryptophan0low10
osteoprotegerin0low10
cholecalciferol0low10
oxymetholone0low10
levetiracetam0low10
sirolimus0low10
carbocyanines0low10
abt-7370low10
cytochrome c-t0low10
e 71070low10
glycolipids0low20
ascorbic acid0low10
transforming growth factor beta0low50
nitrophenols0low10
cyclosporine0medium71
acyclovir0low10
dacarbazine0low10
amg5310low20

Protein Targets (845)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Apoptosis regulator Bcl-X0101
PPM1D protein3003
EWS/FLI fusion protein150015
Bcl-2-like protein 110101
Interferon beta8008
Beta-casein0101
Apoptosis regulator Bcl-20224
Alpha-1B adrenergic receptor0303
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Adenosine receptor A2a0314
BH3-interacting domain death agonist0202
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog0011
Apoptosis regulator BAX 0101
Bcl-2-like protein 10224
Induced myeloid leukemia cell differentiation protein Mcl-10202
Aspartyl/asparaginyl beta-hydroxylase0101
Bcl-2-related protein A10112
Bcl-2 homologous antagonist/killer0213
Bcl-2-like protein 20202
Bcl2-associated agonist of cell death 0101
Bcl-2-binding component 3, isoforms 1/20101
Bcl-2-like protein 100101
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
acetylcholinesterase9009
dopamine D1 receptor3003
15-lipoxygenase, partial5005
pregnane X receptor6006
phosphopantetheinyl transferase6006
RAR-related orphan receptor gamma130013
USP1 protein, partial5005
NFKB1 protein, partial3003
Microtubule-associated protein tau6006
Thrombopoietin3003
AR protein210021
regulator of G-protein signaling 42002
glucocorticoid receptor [Homo sapiens]180018
retinoic acid nuclear receptor alpha variant 1170017
retinoid X nuclear receptor alpha170017
farnesoid X nuclear receptor140014
estrogen nuclear receptor alpha230023
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
arylsulfatase A6006
euchromatic histone-lysine N-methyltransferase 2150015
Bloom syndrome protein isoform 17007
D(1A) dopamine receptor1001
thyroid hormone receptor beta isoform a6006
thyroid hormone receptor beta isoform 2150015
heat shock protein beta-17007
flap endonuclease 16006
geminin220022
peripheral myelin protein 22110011
survival motor neuron protein isoform d100010
muscarinic acetylcholine receptor M13003
Histone deacetylase 30101
Solute carrier family 22 member 60102
Histone deacetylase 40101
Guanine nucleotide-binding protein G1001
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Ataxin-2100010
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
ATP-dependent phosphofructokinase6006
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, Ferritin light chain5005
Thymidine kinase 0101
thioredoxin reductase7007
GLS protein2002
TDP1 protein170017
Smad35005
thyroid stimulating hormone receptor6006
activating transcription factor 68008
Histone H2A.x130013
hemoglobin subunit beta4004
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
lamin isoform A-delta10130013
Solute carrier family 22 member 1 0203
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015016
Bile salt export pump0303
Bile salt export pump019019
Purine nucleoside phosphorylase0202
Thymidine kinase, cytosolic0002
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0303
Cytochrome P450 2J20303
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60003
Thymidine kinase 0101
Solute carrier family 22 member 80103
Canalicular multispecific organic anion transporter 1015015
Thymidine kinase0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
NPYLR7B0022
IDH19009
glycogen synthase kinase-3 beta isoform 10033
mitogen-activated protein kinase 12002
nuclear receptor ROR-gamma isoform 16006
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit9009
Rap guanine nucleotide exchange factor 32002
Epidermal growth factor receptor0213
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0012
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0012
Adenosine receptor A30528
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10012
Inosine-5'-monophosphate dehydrogenase 20314
Endoplasmin0112
Glutamate receptor 291010
Inosine-5'-monophosphate dehydrogenase 1 0303
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10112
Adenosine receptor A30303
Adenosine receptor A2a0236
Adenosine receptor A2b0012
Adenosine receptor A2b0213
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10326
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0012
Adenosine deaminase 0003
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Luciferase3003
hypoxia-inducible factor 1 alpha subunit9009
estrogen receptor 2 (ER beta)100010
progesterone receptor140014
cytochrome P450 family 3 subfamily A polypeptide 49009
G6006
cytochrome P450 2D68008
peroxisome proliferator-activated receptor delta140014
peroxisome proliferator activated receptor gamma140014
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
v-jun sarcoma virus 17 oncogene homolog (avian)6006
nuclear factor erythroid 2-related factor 2 isoform 1160016
Solute carrier organic anion transporter family member 2B1 0101
HLA class I histocompatibility antigen, B alpha chain 6006
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0112
Thrombopoietin receptor0011
Potassium voltage-gated channel subfamily H member 20202
Sodium channel protein type 5 subunit alpha0101
Inositol hexakisphosphate kinase 16006
Solute carrier organic anion transporter family member 1B30102
Potassium voltage-gated channel subfamily D member 30101
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Solute carrier organic anion transporter family member 1B10303
cytochrome P450 2C9, partial6006
Chain A, Hyaluronidase, phage associated0101
GLI family zinc finger 3120012
thioredoxin glutathione reductase2002
estrogen-related nuclear receptor alpha160016
chromobox protein homolog 17007
nuclear factor erythroid 2-related factor 2 isoform 28008
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)6006
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0213
Spike glycoprotein8008
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Beta-lactamase2002
interleukin 86006
glp-1 receptor, partial5005
ATAD5 protein, partial4004
Fumarate hydratase7007
aldehyde dehydrogenase 1 family, member A19009
nuclear receptor subfamily 1, group I, member 3110011
pregnane X nuclear receptor120012
polyprotein7007
67.9K protein9009
Parkin1001
aryl hydrocarbon receptor7007
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
thyroid stimulating hormone receptor6006
peripheral myelin protein 22 isoform 14004
cellular tumor antigen p53 isoform a7007
huntingtin isoform 23003
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 12002
urokinase-type plasminogen activator precursor8008
plasminogen precursor8008
urokinase plasminogen activator surface receptor precursor8008
histone acetyltransferase KAT2A isoform 13003
Cellular tumor antigen p53140014
Integrin beta-35005
Integrin alpha-IIb5005
DNA (cytosine-5)-methyltransferase 10101
D(1A) dopamine receptor1001
Nuclear receptor ROR-gamma4004
Multidrug and toxin extrusion protein 10101
Histone-lysine N-methyltransferase EHMT20101
ATPase family AAA domain-containing protein 59009
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
SMAD family member 26006
SMAD family member 36006
P531001
DNA polymerase iota isoform a (long)3003
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 16006
Gamma-aminobutyric acid receptor subunit pi7108
Gamma-aminobutyric acid receptor subunit beta-17108
Gamma-aminobutyric acid receptor subunit delta7108
Gamma-aminobutyric acid receptor subunit gamma-27108
Gamma-aminobutyric acid receptor subunit alpha-57108
Gamma-aminobutyric acid receptor subunit alpha-37108
Gamma-aminobutyric acid receptor subunit gamma-17108
Gamma-aminobutyric acid receptor subunit alpha-27108
Gamma-aminobutyric acid receptor subunit alpha-47108
Gamma-aminobutyric acid receptor subunit gamma-37108
Gamma-aminobutyric acid receptor subunit alpha-67108
Gamma-aminobutyric acid receptor subunit alpha-17108
Gamma-aminobutyric acid receptor subunit beta-37108
Gamma-aminobutyric acid receptor subunit beta-27108
GABA theta subunit7108
Gamma-aminobutyric acid receptor subunit epsilon7108
Protein-arginine deiminase type-40202
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
Endolysin0011
apical membrane antigen 1, AMA12002
Matrix metalloproteinase-90202
Chain A, Cruzipain1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
vitamin D3 receptor isoform VDRA4004
DNA polymerase kappa isoform 14004
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Vitamin D3 receptor0114
Glycine receptor subunit alpha-10011
Vitamin D3 receptor0011
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Chain A, BCL-2-RELATED PROTEIN A10011
tyrosine-protein kinase Yes1001
relaxin receptor 1 isoform 11001
bcl-2-like protein 11 isoform 10011
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Deoxycytidine kinase0012
Rap guanine nucleotide exchange factor 41001
Inositol monophosphatase 13003
Isocitrate lyase0101
nuclear receptor subfamily 1, group I, member 23003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Estrogen receptor0202
Glucocorticoid receptor0404
Sex hormone-binding globulin0022
Cytochrome P450 1A20101
Glycine receptor subunit alpha-10404
Aldo-keto reductase family 1 member B10202
Alpha-2A adrenergic receptor0202
Beta-3 adrenergic receptor0202
Androgen receptor0606
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Glycine receptor subunit beta0404
Substance-K receptor0202
D(1A) dopamine receptor0202
Glycine receptor subunit alpha-20404
Sodium-dependent noradrenaline transporter 0202
Glycine receptor subunit alpha-30404
5-hydroxytryptamine receptor 2A0202
Sodium-dependent serotonin transporter0202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Kappa-type opioid receptor0202
Alpha-1A adrenergic receptor0202
Sodium-dependent dopamine transporter 0202
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
nonstructural protein 13003
bromodomain adjacent to zinc finger domain 2B2002
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
Lysine-specific demethylase 6A0101
Lysine-specific demethylase 4A0101
Lysine-specific demethylase 5C0101
Histamine H2 receptor1001
Lysine-specific demethylase 2B0101
Deoxyhypusine hydroxylase0101
Lysine-specific demethylase 2A0101
Beta-glucuronidase0101
Corticosteroid-binding globulin0101
Beta-glucuronidase0101
Glucose-6-phosphate 1-dehydrogenase0303
Alpha-synuclein3003
TAR DNA-binding protein 433003
G-protein coupled bile acid receptor 10011
Glucose-6-phosphate 1-dehydrogenase 0101
NPC1-like intracellular cholesterol transporter 10011
Splicing factor 3B subunit 30112
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
corticotropin-releasing hormone receptor 20112
corticotropin releasing factor-binding protein0112
5'-nucleotidase0101
Chain A, Uracil Phosphoribosyltransferase0101
endonuclease IV1001
Skn7p0001
Vpr1001
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1001
Thymidylate synthase0303
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Carbonic anhydrase 20214
Stromelysin-10011
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Carbonic anhydrase 40101
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Carbonic anhydrase 5A, mitochondrial0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Carbonic anhydrase 90203
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
Prostaglandin reductase 10102
Alkaline phosphatase, tissue-nonspecific isozyme0202
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Phospholipase A-2-activating protein0101
chaperonin-containing TCP-1 beta subunit homolog1001
Synaptic vesicle glycoprotein 2A0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase2002
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor2002
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10123
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-72002
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Indoleamine 2,3-dioxygenase 10303
Receptor-interacting serine/threonine-protein kinase 10112
Nuclear receptor subfamily 1 group I member 20033
Nuclear receptor subfamily 1 group I member 20011
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10202
Cytochrome P450 3A40303
Translocator protein0101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60101
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0102
UDP-glucuronosyltransferase 1A40102
UDP-glucuronosyltransferase 2B10 0101
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
UDP-glucuronosyltransferase 1A90001
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Androgen receptor0202
Caspase-71001
caspase-31001
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
C-X-C chemokine receptor type 40101
Atypical chemokine receptor 30011
C-C chemokine receptor type 20101
C-X-C chemokine receptor type 40204
Solute carrier organic anion transporter family member 2A10101
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
thyrotropin-releasing hormone receptor1001
tumor necrosis factor1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
Riboflavin-binding protein0112
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Cytochrome P450 2C190101
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0213
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20112
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Cytochrome P450 3A50101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
polyadenylate-binding protein 10101
Carbonic anhydrase 120101
Carbonic anhydrase 10101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0202
Dipeptidyl peptidase 40101
Histamine H1 receptor0011
Adenosylhomocysteinase0101
RNA-directed RNA polymerase 0112
Ricin0101
Cholinesterase0101
Acetylcholinesterase0101
Xanthine dehydrogenase/oxidase0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]