Mefluidide is a plant growth regulator that inhibits the biosynthesis of gibberellins, a class of plant hormones that promote growth. It is used in agriculture to control the height of crops such as rice, wheat, and barley. Mefluidide has also been studied for its potential use in controlling weeds and other unwanted plants. The compound is synthesized by a multi-step process that involves reacting 2,6-dichlorobenzoyl chloride with 3-methyl-1,2-oxathiolane-2-oxide. Mefluidide has been shown to have a number of effects on plants, including inhibiting stem elongation, promoting root growth, and increasing flower production. It is studied for its potential to improve crop yields and reduce the need for herbicides. However, mefluidide is also known to be toxic to some plants, including soybeans, cotton, and potatoes, and can be harmful to aquatic life.'
Mefluidide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 40896 |
| CHEBI ID | 81930 |
| SCHEMBL ID | 55691 |
| MeSH ID | M0090238 |
| Synonym |
|---|
| acetamide, n-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]- |
| acetanilide, 2',4'-dimethyl-5-((trifluoromethyl)sulfonamido)- |
| embark plant growth regulator |
| embark |
| einecs 258-767-4 |
| embark 2s |
| brn 2819120 |
| n-(2,4-dimethyl-5-(((trifluoromethyl)sulfonyl)amino)phenyl)acetamide |
| epa pesticide chemical code 114002 |
| vistar herbicide |
| trim-cut |
| mbr 12325 |
| vel 3973 |
| vistar |
| mefluidide [ansi:bsi:iso] |
| mefluidide |
| 5'-(1,1,1-trifluoromethanesulfonamido)acet-2',4'-xylidide |
| 5-acetamido-2,4-dimethyltrifluoromethanesulfonanilide |
| acetamide, n-(2,4-dimethyl-5-(((trifluoromethyl)sulfonyl)amino)phenyl)- |
| 5'-(1,1,1-trifluoromethanesulphonamido)acet-2',4'-xylidide |
| 2',4'-dimethyl-5'-(trifluoromethanesulphonamido)acetanilide |
| n-[2,4-dimethyl-5-(trifluoromethylsulfonylamino)phenyl]acetamide |
| 53780-34-0 |
| C18743 |
| unii-499dh82q8o |
| hsdb 6698 |
| 499dh82q8o , |
| SCHEMBL55691 |
| vel-3973 |
| mefluidide [mi] |
| methafluoridamid |
| mbr-12325 |
| mefluidide [iso] |
| mefluidide [hsdb] |
| embark (3m) |
| vistar (3m) |
| CHEBI:81930 |
| mowchem |
| trimcut |
| DTXSID7034709 |
| mfcd01632752 |
| AKOS027461178 |
| mefluidide, analytical standard |
| mefluidide 10 microg/ml in acetonitrile |
| Q22808361 |
| vel3973 |
| 5-acetamido-2,4-dimethyl trifluoromethanesulfonanilide |
Mefluidide treatment of tall fescue prolonged higher-quality herbage into midsummer and resulted in greater forage intake and animal performance. Cow and calf production was greater during July of 1983.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Mefluidide treatment of tall fescue in early spring prolonged higher-quality herbage into midsummer and resulted in greater forage intake and animal performance." | ( Mefluidide treatment of tall fescue pastures: intake and animal performance. Forwood, JR; Kerley, MS; Paterson, JA; Turner, KE, 1990) | 2.44 |
| "Mefluidide-treated pasture increased cow and calf production during August of 1982 (P = .03) and calf production was greater during July of 1983 (P = .09)." | ( Mefluidide effects on smooth brome composition and grazing cow-calf performance. Anderson, BE; Waller, SS; Ward, JK; Wimer, SK, 1986) | 2.44 |
| Class | Description |
|---|---|
| sulfonamide | An amide of a sulfonic acid RS(=O)2NR'2. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (29.35) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||