Page last updated: 2024-12-05

octacosanoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Octacosanoic acid, also known as montanic acid, is a saturated fatty acid with 28 carbon atoms. It is found in many natural sources, including beeswax, carnauba wax, and wool wax. It is also present in some plant oils. Octacosanoic acid has been studied for its potential applications in various fields. For example, it has been investigated as a potential bio-based lubricant, due to its high melting point and good thermal stability. The compound has also been studied for its potential use in the development of biodegradable polymers. Octacosanoic acid has a low toxicity and is generally considered safe for human consumption. However, further research is needed to fully understand its potential benefits and risks. '

octacosanoic acid: RN given refers to parent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

octacosanoic acid : A straight-chain saturated fatty acid that is octacosane in which one of the terminal methyl groups has been oxidised to the corresponding carboxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID10470
CHEMBL ID2261064
CHEBI ID31001
SCHEMBL ID49866
MeSH IDM0188019

Synonyms (40)

Synonym
octaeicosanoic acid
octacosoic acid
ch3-[ch2]26-cooh
1-octacosanoic acid
montanic acid
n-octacosanoic acid
octacosansaeure
octacosancarbonsaeure
CHEBI:31001 ,
n-octaeicosanoic acid
nsc-407311
506-48-9
nsc407311
octacosanoic acid
c28:0
LMFA01010028
octacosanoic acid, synthetic, >=98%
03D7DC3A-50B1-4BBA-9AF7-C86F38E231A2
M1342
4bkl1a0kjy ,
nsc 407311
einecs 208-041-8
unii-4bkl1a0kjy
AKOS015892943
CHEMBL2261064
montan acid ester
SCHEMBL49866
octacosanoic acid,synthetic
mfcd00002812
DTXSID2075051
octacosanoic acid, puriss., synthetic, >=98.5% (gc)
fa 28:0
octacosanoicacid
A855122
FT-0706014
octacosoate
Q911196
C21933
HY-N8425
CS-0144141

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Meanwhile, no adverse effects on reproductive performance, or on embryonic or fetal development, including visceral and skeletal examination, were seen in any of the groups administered D-003."( Lack of developmental toxicity of D-003: a mixture of long-chain fatty acids in rats.
Acosta, CP; Gámez, R; García, H; Goicochea, E; González, JE; Rodríguez, MD, 2003
)
0.32

Dosage Studied

ExcerptRelevanceReference
"The present study demonstrates that octacosanoic acid is formed after incubation of fibroblast cultures with (3)H-octacosanol and after oral dosing with policosanol to rats."( In vitro and in vivo study of octacosanol metabolism.
Fernández, I; González, L; González, RM; Marrero, D; Más, R; Menéndez, R,
)
0.41
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
straight-chain saturated fatty acidAny saturated fatty acid lacking a side-chain.
ultra-long-chain fatty acidAny very long-chain fatty acid which has a chain length greater than C27.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

PathwayProteinsCompounds
Elongation of (very) long chain fatty acids345

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1063391Induction of dendrite extension in rat cortical neurons assessed as inhibition of amyloid beta (25 to 35)-induced neuronal degeneration at 1 uM after 4 days by fluorescence microscopic analysis2014Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2
Synthesis of long-chain fatty acid derivatives as a novel anti-Alzheimer's agent.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (15)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's9 (60.00)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 24.18

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index24.18 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index5.37 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (24.18)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]