Bronchopulmonary Sequestration

A developmental anomaly in which a mass of nonfunctioning lung tissue lacks normal connection with the tracheobroncheal tree and receives an anomalous blood supply originating from the descending thoracic or abdominal aorta. The mass may be extralobar, i.e., completely separated from normally connected lung, or intralobar, i.e., partly surrounded by normal lung.

Synonym
Bronchopulmonary Sequestrations
Sequestrations, Bronchopulmonary
Sequestration, Bronchopulmonary
Sequestration, Pulmonary
Pulmonary Sequestrations
Pulmonary Sequestration
Sequestrations, Pulmonary
Bronchopulmonary Sequestration

Excerpt	Reference
"Pulmonary sequestration is a rare congenital or acquired pulmonary anomaly."	( Connery, C; Shapiro, JM; Shibli, M, 2003)
"Bronchopulmonary sequestration is a rare malformation characterized by lung tissue fed by one or several aberrant systemic arteries."	( Abada, D; Aouina, H; Baccar, MA; Ben Amar, J; Bouacha, H; Dhahri, B; El Gharbi, L; Kilani, T; Saloua, S, 2010)
"Patients with pulmonary sequestration are at risk of life-threatening bleeding during lung resection."	( Eguchi, T; Hamanaka, K; Matsuoka, S; Miura, K; Shimizu, K; Takeda, T, 2021)

Excerpt	Reference
"No significant degree of pulmonary sequestration was detected in any measurements after protamine was administered in the aprotinin and pentoxifylline (PTX) groups."	( Arar, C; Canbaz, S; Cikirikcioglu, M; Duran, E; Ege, T; Sunar, H; Yuksel, V, 2004)
"We report a baby with intralobar pulmonary sequestration who was successfully treated with a new embolization agent, Onyx."	( Boyvat, F; Erdoğan, I; Gürsu, AH; Varan, B, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	21 (28.00)	23.3326
1990's	15 (20.00)	12.5806
2000's	15 (20.00)	18.1394
2010's	16 (21.33)	28.8240
2020's	8 (10.67)	9.53

Drug	Relationship Strength	Studies	Trials
chlorine	low	1	0
dimethyl sulfoxide	low	1	0
inositol	low	1	0
succinic acid	low	1	0
normetanephrine	low	1	0
furosemide	low	1	0
guaifenesin	low	3	0
hydroxyurea	low	1	0
iohexol	low	2	0
iopromide	low	2	0
isoniazid	low	1	0
ketoconazole	low	1	0
ofloxacin	low	1	0
pentoxifylline	medium	1	1
isoflurophate	low	1	0
adenosine diphosphate	low	1	0
methylene blue	low	1	0
cytarabine	low	1	0
ornithine	low	1	0
methylprednisolone	medium	2	1
vinyl acetate	low	1	0
citrulline	low	1	0
betamethasone	low	3	0
malondialdehyde	low	1	0
ethambutol	low	1	0
ethamsylate	low	1	0
technetium	low	11	0
gadolinium	low	1	0
xenon	low	2	0
barium sulfate	low	2	0
tetradecanoylphorbol acetate	low	1	0
4-chlorophenyl methyl sulfide	low	1	0
homocitrulline	low	1	0
xenon radioisotopes	low	2	0
triazoles	low	2	0
fluorodeoxyglucose f18	low	1	0
voriconazole	low	2	0
methionyl-leucyl-phenylalanine	low	1	0
bosentan anhydrous	low	1	0
fr 139317	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
n-formylmethionine leucyl-phenylalanine	low	1	0
thioguanine anhydrous	low	1	0
digoxin	low	1	0
leukotriene b4	low	1	0
leukotriene c4	low	1	0
amphotericin b	low	1	0
thromboxane b2	low	1	0
phenylephrine hydrochloride	low	1	0
bw b70c	low	1	0
indium	low	2	0
isavuconazole	low	1	0
mocetinostat	low	6	0
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc	low	1	0
indocyanine green	low	5	0
irl 1620	low	1	0
sodium pertechnetate tc 99m	low	1	0
piperacillin, tazobactam drug combination	low	1	0
cardiovascular agents	low	1	0
apyrase	low	1	0
phosphorus radioisotopes	low	1	0

Protein Targets (648)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Chain A, Cruzipain	4	0	0	4
regulator of G-protein signaling 4	6	0	0	6
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	5	0	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
thyroid hormone receptor beta isoform a	5	0	0	5
Cellular tumor antigen p53	9	0	0	9
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	0	1	1
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	0	1	1
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
interleukin 8	2	0	0	2
phosphopantetheinyl transferase	5	0	0	5
GLS protein	6	0	0	6
glucocorticoid receptor [Homo sapiens]	11	0	0	11
farnesoid X nuclear receptor	9	0	0	9
peroxisome proliferator-activated receptor delta	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	8	0	0	8
tumor necrosis factor	2	0	0	2
vitamin D3 receptor isoform VDRA	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	12	0	0	12
peripheral myelin protein 22	3	0	0	3
lamin isoform A-delta10	10	0	0	10
Cytochrome P450 1A2	0	2	0	2
Cytochrome P450 3A4	0	8	0	9
Cytochrome P450 2D6	0	2	0	2
Cytochrome P450 2C9	0	3	0	3
Cytochrome P450 2C19	0	4	0	4
Nuclear receptor ROR-gamma	3	1	1	5
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
pregnane X receptor	2	0	0	2
GLI family zinc finger 3	11	0	0	11
AR protein	12	0	0	12
progesterone receptor	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
estrogen-related nuclear receptor alpha	9	0	0	9
pregnane X nuclear receptor	9	0	0	9
estrogen nuclear receptor alpha	15	0	0	15
IDH1	6	0	0	6
aryl hydrocarbon receptor	5	0	0	5
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
galanin receptor type 3	0	1	0	1
ATP-binding cassette sub-family C member 3	0	13	0	13
Multidrug resistance-associated protein 4	0	13	0	13
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Bile salt export pump	0	15	0	15
Glucocorticoid receptor	0	6	1	7
Glycine receptor subunit alpha-1	0	6	0	6
Glutamate receptor 2	6	0	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Canalicular multispecific organic anion transporter 1	0	12	0	12
ORF73	0	0	1	1
RAR-related orphan receptor gamma	9	0	0	9
estrogen receptor 2 (ER beta)	6	0	0	6
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
G	8	0	0	8
peroxisome proliferator activated receptor gamma	7	0	0	7
activating transcription factor 6	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
heat shock protein beta-1	2	0	0	2
nuclear receptor ROR-gamma isoform 1	5	0	0	5
Bile salt export pump	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Interferon beta	9	0	0	9
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	2	0	2
Endothelin-1 receptor	0	2	1	3
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Endothelin-1 receptor	0	1	0	1
Inositol hexakisphosphate kinase 1	8	0	0	8
cytochrome P450 2C9, partial	8	0	0	8
Chain A, Ferritin light chain	3	0	0	3
ATAD5 protein, partial	5	0	0	5
TDP1 protein	10	0	0	10
Microtubule-associated protein tau	3	0	0	3
nonstructural protein 1	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	12	0	0	12
Bloom syndrome protein isoform 1	4	0	0	4
peripheral myelin protein 22 isoform 1	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
flap endonuclease 1	4	0	0	4
neuropeptide S receptor isoform A	2	0	0	2
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 2	0	3	0	5
Carbonic anhydrase 4	0	3	0	4
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
endonuclease IV	2	0	0	2
glp-1 receptor, partial	3	0	0	3
thioredoxin reductase	7	0	0	7
USP1 protein, partial	2	0	0	2
EWS/FLI fusion protein	9	0	0	9
67.9K protein	4	0	0	4
LMP1 [Human herpesvirus 4]	0	0	0	2
Histone H2A.x	5	0	0	5
chromobox protein homolog 1	3	0	0	3
thyroid hormone receptor beta isoform 2	6	0	0	6
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase iota isoform a (long)	4	0	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
geminin	12	0	0	12
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	0	0	1
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	1	0	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Ataxin-2	4	0	0	4
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
ATP-dependent phosphofructokinase	4	0	0	4
Chain A, Beta-lactamase	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
PAX8	0	0	0	2
SMAD family member 2	3	0	0	3
PPM1D protein	4	0	0	4
SMAD family member 3	3	0	0	3
STAT3, partial	0	1	0	1
thioredoxin glutathione reductase	4	0	0	4
Smad3	3	0	0	3
retinoid X nuclear receptor alpha	5	0	0	5
alpha-galactosidase	1	0	0	1
thyroid stimulating hormone receptor	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
ras-related protein Rab-9A	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
lethal factor (plasmid)	2	0	0	2
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Integrin beta-3	2	0	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	4
Integrin alpha-IIb	2	0	0	2
Replicase polyprotein 1ab	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
ATPase family AAA domain-containing protein 5	3	0	0	3
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Pantothenate synthetase	0	2	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
cytochrome P450 2C9 precursor	1	0	0	1
cytochrome P450 3A4 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	3	1	0	4
Gamma-aminobutyric acid receptor subunit beta-1	3	1	0	4
Gamma-aminobutyric acid receptor subunit delta	3	1	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	3	1	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	3	1	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	3	1	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	3	1	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	3	1	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	3	1	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	3	1	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	3	1	0	4
Histamine H2 receptor	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	3	1	0	4
Gamma-aminobutyric acid receptor subunit beta-3	3	1	0	4
Gamma-aminobutyric acid receptor subunit beta-2	3	1	0	4
GABA theta subunit	3	1	0	4
Gamma-aminobutyric acid receptor subunit epsilon	3	1	0	4
Sialin	0	1	0	1
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
thyrotropin-releasing hormone receptor	1	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Carbonic anhydrase 12	0	1	0	2
Albumin	0	1	1	2
Carbonic anhydrase 3	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Carbonic anhydrase 6	0	1	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	3
Carbonic anhydrase 7	0	1	0	2
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Spike glycoprotein	7	0	0	7
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Carbonic anhydrase 9	0	2	0	4
Multidrug and toxin extrusion protein 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	2
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
acetylcholinesterase	5	0	0	5
Fumarate hydratase	2	0	0	2
NFKB1 protein, partial	2	0	0	2
thyroid stimulating hormone receptor	2	0	0	2
polyprotein	2	0	0	2
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Stromelysin-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Urease subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Urease subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Amyloid-beta precursor protein	0	2	0	2
TAR DNA-binding protein 43	2	0	0	2
Sodium/myo-inositol cotransporter 2	0	1	0	1
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
cytochrome P450 2D6	3	0	0	3
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	0	1	1
Lysosomal protective protein	0	1	0	1
Fatty acid synthase	0	1	0	1
Acetylcholinesterase	0	3	1	4
Liver carboxylesterase	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
Luciferase	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
histone acetyltransferase KAT2A isoform 1	3	0	0	3
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Estrogen receptor beta	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	3	0	3
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Aromatase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Translocator protein	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	1	0	1
Substance-K receptor	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	1	3
Thromboxane-A synthase	0	1	0	1
Histamine H2 receptor	0	2	0	2
Gonadotropin-releasing hormone receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	1	3
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Leukotriene B4 receptor 1	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Cysteinyl leukotriene receptor 2	0	0	1	1
Cysteinyl leukotriene receptor 1	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
hypothetical protein, conserved	2	0	0	2
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
caspase-3	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
Vpr	2	0	0	2
survival motor neuron protein isoform d	3	0	0	3
muscleblind-like protein 1 isoform 1	2	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Alpha-1B adrenergic receptor	0	4	0	4
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Cruzipain	0	1	0	1
Alpha-synuclein	1	1	0	2
Alpha-1A adrenergic receptor	0	4	0	4
Guanine nucleotide-binding protein G	1	0	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Androgen receptor	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Histone deacetylase 3	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase 1	0	2	0	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	2	0	2
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 5	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Formyl peptide receptor-related sequence 1	0	0	1	1
fMet-Leu-Phe receptor	0	2	2	4
N-formyl peptide receptor 2	0	0	2	2
FML2_HUMAN	0	0	1	1
arylsulfatase A	3	0	0	3
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
streptokinase A precursor	0	0	1	1
Trypsin	0	0	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
dopamine D1 receptor	1	0	0	1
vasopressin V1b receptor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
muscarinic acetylcholine receptor M1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Tumor necrosis factor	0	1	0	1
Cholinesterase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
GALC protein	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Epidermal growth factor receptor	0	1	0	1
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
Lysine-specific demethylase 4E	0	1	0	1
Delta-aminolevulinic acid dehydratase	0	1	0	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
NADP-dependent malic enzyme, mitochondrial	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Solute carrier family 13 member 3	0	1	0	1
Egl nine homolog 1	0	1	1	2
Methyl-accepting chemotaxis protein NahY	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
DNA polymerase kappa isoform 1	1	0	0	1
Serine/threonine-protein kinase D3	0	0	1	1
Protein kinase C gamma type	0	1	1	2
Protein kinase C beta type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Protein kinase C alpha type	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Protein kinase C eta type	0	0	1	1
Protein kinase C iota type	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Protein kinase C theta type	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	1	1	2
Serine/threonine-protein kinase D1	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
apical membrane antigen 1, AMA1	1	0	0	1
hemoglobin subunit beta	1	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Adenosine receptor A3	0	2	0	2
Apoptosis regulator Bcl-2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Mitogen-activated protein kinase 3	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 2B6	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bronchopulmonary Sequestration

Synonyms(8)

Research Excerpts

Overview

Treatment

Research

Studies (75)

Protein Targets (648)

Bronchopulmonary Sequestration

Synonyms(8)

Research Excerpts

Overview

Treatment

Research

Studies (75)

Drugs Studied (75)

Protein Targets (648)