Page last updated: 2024-09-27

Acne Keloid

A type of acneiform disorder in which secondary pyogenic infection in and around pilosebaceous structures ends in keloidal scarring. It manifests as persistent folliculitis of the back of the neck associated with occlusion of the follicular orifices. It is most often encountered in black or Asian men.

Synonyms(8)

Synonym
Acne Keloid
Nuchal Keloid Acne
Dermatitis Papillaris Capillitii
Lichen Keloidalis Nuchae
Folliculitis Keloidalis Nuchae
Folliculitis Keloidalis
Acne Keloidalis
Keloidal Acne

Research Excerpts

Overview

ExcerptReference
"Acne keloidalis nuchae (AKN) is a chronic idiopathic reaction responsible for a great deal of discomfort in patients, and requires radical treatment to be eradicated."( Ansorena, JM; Bestue, M; Cordero, A; Martinho, A; Pestalardo, CM, 1995)
"Acne keloidalis (AK) is an important cause of morbidity in Nigeria and accounts for 1."( Akanji, AO; George, AO; Nduka, EU; Odusan, O; Olasode, JB, 1993)
"Acne keloidalis is a primary form of scarring alopecia, and many of the histologic findings closely resemble those found in certain other forms of cicatricial alopecia."( Homoky, C; Pratt, L; Sau, P; Sperling, LC, 2000)
"Acne keloidalis (AK) is a disease affecting primarily African American men."( Callender, VD; Carroll, CL; Feldman, SR; Haverstock, CL; Young, CM, 2005)
"BACKGROUND Acne keloidalis nuchae is a chronic condition affecting young adult males of African origin."( Adegbidi, H; Atadokpede, F; do Ango-Padonou, F; Yedomon, H, 2005)
"Acne keloidalis is characterized by firm skin-colored papules on the surface of the neck and scalp."( Deng, A; Gaspari, A; Sina, B; Sterling, JB, 2007)
"Acne keloidalis nuchae (AKN) is an inflammatory disease related to the spectrum of keloidal scarring alopecias."( Verma, SB; Wollina, U, 2010)
"Folliculitis keloidalis is a cicatricial alopecia with a mixed inflammatory infiltrate."( Ioannides, D; Rigopoulos, D; Stamatios, G, 2015)
"Individuals with acne keloidalis nuchae should avoid frequent close shaves or short haircuts on the nuchal area of the scalp."( Frazier, WT; Proddutur, S; Swope, K, 2023)

Treatment

ExcerptReference
"A man developed acne keloidalis-like lesions in the scalp during treatment with diphenylhydantoin and carbamazepine for epilepsy."( Ben-Dor, D; Grunwald, MH; Halevy, S; Livni, E, 1990)

Research

Studies (58)

TimeframeStudies, This Condition (%)All Conditions %
pre-19907 (12.07)23.3326
1990's10 (17.24)12.5806
2000's18 (31.03)18.1394
2010's20 (34.48)28.8240
2020's3 (5.17)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminolevulinic acid0medium11
salicylic acid0low100
lactic acid0low10
hydroquinone0low10
phenytoin0low10
azelaic acid0low10
carbamazepine0low10
dapsone0low10
fluorouracil0low10
lidocaine0medium21
ketoconazole0low10
khellin0low100
metronidazole0medium11
minoxidil0low10
prilocaine0medium11
tetracaine0medium11
valine0low10
triamcinolone acetonide0medium31
pantothenic acid0low10
fluocortolone0low10
betamethasone0low10
gluconic acid0medium11
copper gluconate0medium11
lithium carbonate0low10
betamethasone valerate0medium11
erbium0medium11
triamcinolone0medium21
fenticonazole0low10
betamethasone sodium phosphate0low10
nsc-1727550low10
griseofulvin0low20
tacrolimus0low10
clindamycin0low10
zithromax0low10
bromochloroacetic acid0low10
fusidic acid0low10
isotretinoin0medium41
sirolimus0low10
clobetasol0medium11
chlortetracycline0low10
minocycline0low10
salicylates0low10
hyaluronoglucosaminidase0low10
cyclosporine0low30
acyclovir0low10
valacyclovir0low10

Protein Targets (864)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Ferritin light chain5005
Thymidine kinase 0101
thioredoxin reductase100010
phosphopantetheinyl transferase7007
GLS protein6006
TDP1 protein200020
Smad34004
thyroid stimulating hormone receptor100010
EWS/FLI fusion protein7007
arylsulfatase A8008
euchromatic histone-lysine N-methyltransferase 2170017
activating transcription factor 67007
Histone H2A.x7007
Bloom syndrome protein isoform 16006
hemoglobin subunit beta3003
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
lamin isoform A-delta10150015
Solute carrier family 22 member 1 0304
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015015
Solute carrier family 22 member 60304
Bile salt export pump0707
Bile salt export pump019019
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0718
Cytochrome P450 2J20404
Disintegrin and metalloproteinase domain-containing protein 171001
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60102
Thymidine kinase 0101
Solute carrier family 22 member 80103
Canalicular multispecific organic anion transporter 1015015
Thymidine kinase0101
Chain A, Beta-lactamase6006
bromodomain adjacent to zinc finger domain 2B5005
geminin210021
Gamma-aminobutyric acid receptor subunit rho-10101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10506
Glutamate receptor 40101
Solute carrier family 15 member 10303
Solute carrier family 15 member 20304
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, Diaminopimelate decarboxylase0101
Chain B, Diaminopimelate decarboxylase0101
RAR-related orphan receptor gamma140014
NFKB1 protein, partial3003
GLI family zinc finger 3160016
estrogen receptor 2 (ER beta)8008
cytochrome P450 family 3 subfamily A polypeptide 4140014
estrogen-related nuclear receptor alpha180018
estrogen nuclear receptor alpha230023
peripheral myelin protein 22 isoform 16006
muscleblind-like protein 1 isoform 15005
TAR DNA-binding protein 436006
ATP-dependent phosphofructokinase5005
pregnane X receptor5005
AR protein200020
progesterone receptor100010
glucocorticoid receptor [Homo sapiens]160016
farnesoid X nuclear receptor8008
pregnane X nuclear receptor150015
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
IDH18008
aryl hydrocarbon receptor100010
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a130013
nuclear receptor subfamily 1, group I, member 24004
thyroid hormone receptor beta isoform a8008
nuclear factor erythroid 2-related factor 2 isoform 28008
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 1140014
Voltage-dependent calcium channel gamma-2 subunit9009
Glucocorticoid receptor0606
Glycine receptor subunit alpha-10606
Glutamate receptor 29009
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
ORF730011
peroxisome proliferator activated receptor gamma110011
thyroid hormone receptor beta isoform 2110011
SMAD family member 25005
SMAD family member 35005
nuclear receptor subfamily 1, group I, member 3110011
retinoic acid nuclear receptor alpha variant 1130013
retinoid X nuclear receptor alpha110011
G7007
cytochrome P450 2D69009
thyroid stimulating hormone receptor9009
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 7007
Inositol hexakisphosphate kinase 17007
cytochrome P450 2C9, partial7007
aldehyde dehydrogenase 1 family, member A1120012
Cellular tumor antigen p53120012
Nuclear receptor ROR-gamma6118
acetylcholinesterase4004
USP1 protein, partial7007
mitogen-activated protein kinase 17007
Vpr2002
Albumin0011
Major prion protein0011
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0303
Sodium channel protein type 3 subunit alpha0202
UDP-glucuronosyltransferase 2B70002
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0305
Potassium voltage-gated channel subfamily H member 20404
Sodium channel protein type 9 subunit alpha0606
Frizzled-80011
P2X purinoceptor 40101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Microtubule-associated protein tau7007
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
vitamin D3 receptor isoform VDRA5005
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Solute carrier family 22 member 80101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, BCL-2-RELATED PROTEIN A10011
Chain A, Cruzipain4004
Luciferase5005
acid sphingomyelinase1001
interleukin 85005
PAX80001
glp-1 receptor, partial5005
15-lipoxygenase, partial2002
hypoxia-inducible factor 1 alpha subunit7007
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
PINK11001
67.9K protein5005
glucocerebrosidase1001
Parkin4004
peroxisome proliferator-activated receptor delta9009
heat shock protein 900011
caspase-32002
calcineurin A1, putative0011
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
cytochrome P450 2D6 isoform 12002
hepatocyte nuclear factor 4-alpha isoform 20101
cellular tumor antigen p53 isoform a2002
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor3003
perilipin-50101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d3003
transcriptional regulator ERG isoform 33003
heat shock protein beta-17007
huntingtin isoform 22002
importin subunit beta-1 isoform 12002
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 11001
flap endonuclease 15005
protein AF-9 isoform a0001
snurportin-12002
melanocortin receptor 40101
CAAX prenyl protease0001
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
bcl-2-related protein A10101
urokinase plasminogen activator surface receptor precursor3003
nuclear receptor ROR-gamma isoform 17007
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
DNA polymerase kappa isoform 13003
peripheral myelin protein 228008
cytochrome P450 3A4 isoform 19009
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
lethal factor (plasmid)3003
Gamma-aminobutyric acid receptor subunit pi91010
Synaptojanin-20101
Solute carrier family 22 member 20101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0102
Integrin beta-32002
72 kDa type IV collagenase0101
Integrin alpha-IIb2002
Matrix metalloproteinase-90202
Gamma-aminobutyric acid receptor subunit beta-191010
Gamma-aminobutyric acid receptor subunit delta91010
Gamma-aminobutyric acid receptor subunit gamma-291010
Gamma-aminobutyric acid receptor subunit alpha-591010
Gamma-aminobutyric acid receptor subunit alpha-391010
Gamma-aminobutyric acid receptor subunit gamma-191010
Gamma-aminobutyric acid receptor subunit alpha-291010
Gamma-aminobutyric acid receptor subunit alpha-491010
Gamma-aminobutyric acid receptor subunit gamma-391010
Trypanothione reductase0101
Gamma-aminobutyric acid receptor subunit alpha-691010
Alpha-synuclein2103
Histamine H2 receptor3003
Spike glycoprotein4004
Gamma-aminobutyric acid receptor subunit alpha-191010
Gamma-aminobutyric acid receptor subunit beta-391010
Gamma-aminobutyric acid receptor subunit beta-291010
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 42002
GABA theta subunit91010
Multidrug and toxin extrusion protein 10202
ATPase family AAA domain-containing protein 58008
Ataxin-28008
Gamma-aminobutyric acid receptor subunit epsilon91010
Spermine oxidase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40606
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
Myeloperoxidase0101
Dihydrofolate reductase0101
5-hydroxytryptamine receptor 60101
Fumarate hydratase1001
PPM1D protein2002
polyprotein1001
Chain A, Uracil Phosphoribosyltransferase0101
endonuclease IV3003
Skn7p0001
ATAD5 protein, partial6006
Thrombopoietin2002
nonstructural protein 12002
chromobox protein homolog 1100010
serine/threonine-protein kinase mTOR isoform 13003
survival motor neuron protein isoform d6006
Solute carrier family 22 member 80001
Epidermal growth factor receptor0112
Amyloid-beta precursor protein1102
Thymidylate synthase0101
Aromatase0303
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
thioredoxin glutathione reductase4004
streptokinase A precursor0022
Albumin0123
Estrogen receptor0011
Guanine nucleotide-binding protein G1001
Estrogen receptor beta0011
Canalicular multispecific organic anion transporter 10101
Broad substrate specificity ATP-binding cassette transporter ABCG20303
large T antigen0202
Chain A, 2-oxoglutarate Oxygenase4004
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Heme oxygenase 1 0101
Heme oxygenase 20101
Lanosterol 14-alpha demethylase0415
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Nrf21001
DNA polymerase III, partial1001
regulator of G-protein signaling 45005
Caspase-73003
NPC intracellular cholesterol transporter 1 precursor1001
caspase-33003
ras-related protein Rab-9A1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
M-phase phosphoprotein 82002
muscarinic acetylcholine receptor M14004
Acetylcholinesterase0101
Polyphenol oxidase 20204
Carbonic anhydrase 120202
Carbonic anhydrase 10303
Carbonic anhydrase 20303
Carbonic anhydrase 30202
Tyrosinase0101
Tyrosinase0101
Prolyl 4-hydroxylase subunit alpha-10202
Carbonic anhydrase 40202
Carbonic anhydrase 60202
Carbonic anhydrase 5A, mitochondrial0202
Carbonic anhydrase 70202
Carbonic anhydrase 90202
Carbonic anhydrase0202
Carbonic anhydrase 150202
Carbonic anhydrase 130202
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0202
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)1001
Ornithine decarboxylase0002
Adenosine receptor A30404
Retinoic acid receptor alpha0224
Alpha-1B adrenergic receptor0404
Alpha-2B adrenergic receptor0404
Retinoic acid receptor gamma0224
Retinoic acid receptor beta0224
Cellular retinoic acid-binding protein 20022
Mitogen-activated protein kinase 10213
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10203
5-hydroxytryptamine receptor 2B0404
Alpha-1A adrenergic receptor0404
Cellular retinoic acid-binding protein 10022
Mitogen-activated protein kinase 140112
Olfactory receptor 51E20101
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Chymotrypsinogen A0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0202
ATP-dependent translocase ABCB10202
Epoxide hydrolase 10001
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
ATP-dependent translocase ABCB10303
Cytochrome P450 2C11 0101
Cytochrome P450 3A40618
Steroid 21-hydroxylase0101
Alpha-2A adrenergic receptor0202
Cytochrome P450 2C80101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0101
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Cytochrome P450 11B1, mitochondrial0101
Translocator protein0101
Cytochrome P450 7A1 0101
Cytochrome P450 11B2, mitochondrial0101
Estrogen receptor0102
ATP-dependent translocase ABCB10202
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Sodium-dependent noradrenaline transporter 0202
Thromboxane-A synthase 0101
Histamine H2 receptor0202
Gonadotropin-releasing hormone receptor0112
Sodium-dependent serotonin transporter0202
Type-1 angiotensin II receptor0101
Malate dehydrogenase, cytoplasmic0101
Delta-type opioid receptor0202
Cytochrome P450 4F20101
Sodium-dependent dopamine transporter 0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
GALC protein1001
GTP-binding nuclear protein Ran isoform 11001
histone acetyltransferase KAT2A isoform 16006
Cytochrome P450 1A10202
Cytochrome P450 1A20213
Cytochrome P450 2D60112
Cytochrome P450 2C190213
Cytochrome P450 1B10101
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 20101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 5 subunit alpha0303
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0303
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Stromelysin-10112
Matrilysin0101
Multidrug transporter MdfA0101
Protein mono-ADP-ribosyltransferase PARP150101
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Inositol monophosphatase 12002
Type II pantothenate kinase0001
Type III pantothenate kinase0001
Gamma-aminobutyric acid 0101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Dihydrofolate reductase 0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
5-hydroxytryptamine receptor 1A0202
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Sodium channel protein type 1 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0101
Sodium channel protein type 2 subunit alpha0202
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
chaperonin-containing TCP-1 beta subunit homolog1001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Tyrosine-protein phosphatase non-receptor type 10103
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
Prostaglandin G/H synthase 20101
5'-AMP-activated protein kinase subunit gamma-10012
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20012
5'-AMP-activated protein kinase subunit beta-10001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Nuclear receptor subfamily 1 group I member 20022
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0213
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Solute carrier organic anion transporter family member 1B10202
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Cytochrome P450 3A50101
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
5-hydroxytryptamine receptor 40202
Amine oxidase [flavin-containing] A0101
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
cGMP-gated cation channel alpha-10011
Sodium channel protein type 7 subunit alpha0101
Sigma non-opioid intracellular receptor 10202
Sodium channel protein type 8 subunit alpha0101
Chain A, Nuclear Receptor ROR-beta0101
thyrotropin-releasing hormone receptor1001
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor RXR-alpha0224
Alpha-1D adrenergic receptor0101
Retinoic acid receptor RXR-beta0224
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
procathepsin L isoform 1 preproprotein0101
Valacyclovir hydrolase0001
Chain A, Arginase 10101
Large neutral amino acids transporter small subunit 10101
twin arginine protein translocation system - TatA protein0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]