clobetasol and Acne-Keloid

Acne keloidalis (AK) is a disease affecting primarily African American men. Topical steroids are a widely accepted treatment of AK; however, no studies have been published investigating their effectiveness. The purpose of this open-label study was to assess the efficacy and tolerability of clobetasol propionate 0.05% and betamethasone valerate 0.12% foams in the treatment of AK in 20 African American patients. These patients were treated for 8 to 12 weeks using a pulsed-dose regimen. We found topical clobetasol propionate foam to be effective in improving AK, and our patients found the foam vehicle to be cosmetically acceptable.

Topics: Acne Keloid; Administration, Topical; Adult; Anti-Inflammatory Agents; Betamethasone Valerate; Black or African American; Clobetasol; Female; Humans; Male; Middle Aged; Quality of Life; Scalp Dermatoses; Treatment Outcome