Triploid

Polyploidy with three sets of chromosomes. Triploidy in humans are 69XXX, 69XXY, and 69XYY. It is associated with HOLOPROSENCEPHALY; ABNORMALITIES, MULTIPLE; PARTIAL HYDATIDIFORM MOLE; and MISCARRAGES.

Synonym
Triploid
Triploidy

Excerpt	Reference
"Triploids are typically viewed as bridges between diploids and tetraploids but rarely as parental genomes of high-level hybrids and polyploids."	( Kovarík, A; Lysak, MA; Mandáková, T; Marhold, K; Mummenhoff, K; Shimizu, KK; Shimizu-Inatsugi, R; Zozomová-Lihová, J, 2013)
"Triploidy is a highly lethal condition, and is thus very rarely observed in live births."	( Erol, M; Erol, O; Karaca, M, 2013)
"As most triploids are sterile, we embarked on a detailed analysis of the C."	( Gloss, AD; Lysak, MA; Mandáková, T; Whiteman, NK, 2016)
"Embryonic triploidy is a noteworthy event associated with pregnancy complications and loss."	( Evans, JP, 2020)

Excerpt	Reference
"Regardless of feeding treatment, triploids displayed slightly greater feed intake and specific growth rates than diploids."	( Cleveland, BM; Weber, GM, 2013)
"The E2 treated triploids and nontreated triploids were all male."	( Dabrowski, K; Delomas, TA, 2018)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	4 (4.40)	23.3326
1990's	0 (0.00)	12.5806
2000's	1 (1.10)	18.1394
2010's	59 (64.84)	28.8240
2020's	27 (29.67)	9.53

Drug	Relationship Strength	Studies
adenine	low	1
ammonium hydroxide	low	1
chlorine	low	1
lactic acid	low	1
methanol	low	2
phenanthrene	low	1
sulfuric acid	low	1
caffeine	low	1
chlorpyrifos	low	2
n(6),n(6)-dimethyladenine	low	1
domperidone	low	1
furosemide	low	2
letrozole	low	1
mechlorethamine	low	1
methyl salicylate	low	1
nikethamide	low	2
thyroxine	low	1
triiodothyronine	low	1
sucrose	low	1
ethinyl estradiol	low	2
ethyl methanesulfonate	low	1
colchicine	low	3
dimethylformamide	low	1
histidine	low	1
isoprene	low	1
pentane	low	1
catechin	low	1
limestone	low	1
dihydrotestosterone	low	1
c.i. 42510	low	1
sabinene	low	7
silver	low	1
cadmium	low	1
copper sulfate	low	1
ozone	low	3
butachlor	low	2
adenosine	low	1
trazodone hydrochloride	low	3
procyanidin	low	1
proline	low	1
cucurbitaceae	low	1
lignin	low	5
3-octanone	low	1
glycogen	low	2
eicosapentaenoic acid	low	1
2,4-hexadienal	low	1
glycosides	low	1
isomethyleugenol	low	1
fh535	low	1
rutin	low	1
misoprostol	low	1
phosphorus	low	1
abscisic acid	low	1
calpain	low	1
sodium ethylxanthate	low	1
ascorbic acid	low	1
transforming growth factor beta	low	2
bassianolide	low	2
gibberellins	low	1
ovaprim	low	1
phenanthrenes	low	1

Protein Targets (575)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	17	0	0	17
GLI family zinc finger 3	15	0	0	15
AR protein	22	0	0	22
aldehyde dehydrogenase 1 family, member A1	9	0	0	9
retinoid X nuclear receptor alpha	16	0	0	16
estrogen-related nuclear receptor alpha	22	0	0	22
estrogen nuclear receptor alpha	23	0	0	23
peroxisome proliferator activated receptor gamma	10	0	0	10
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
activating transcription factor 6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	13	0	0	13
thyroid hormone receptor beta isoform a	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	18	0	0	18
Cellular tumor antigen p53	10	0	0	10
Nuclear receptor ROR-gamma	5	0	0	5
acetylcholinesterase	6	0	0	6
progesterone receptor	10	0	0	10
retinoic acid nuclear receptor alpha variant 1	15	0	0	15
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	6	0	0	6
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	11	0	0	11
nuclear receptor subfamily 1, group I, member 3	12	0	0	12
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
glucocorticoid receptor [Homo sapiens]	15	0	0	15
pregnane X nuclear receptor	16	0	0	16
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
heat shock protein beta-1	5	0	0	5
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
lamin isoform A-delta10	11	0	0	11
Voltage-dependent calcium channel gamma-2 subunit	9	0	0	9
Bile salt export pump	0	10	0	10
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	0	2
Glutamate receptor 2	9	0	0	9
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	2	0	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	4	0	4
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	5	0	0	5
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	3	0	0	3
NPYLR7B	0	0	1	1
arylsulfatase A	3	0	0	3
IDH1	4	0	0	4
Histone H2A.x	7	0	0	7
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
mitogen-activated protein kinase 1	4	0	0	4
flap endonuclease 1	4	0	0	4
nuclear receptor ROR-gamma isoform 1	4	0	0	4
peripheral myelin protein 22	9	0	0	9
survival motor neuron protein isoform d	2	0	0	2
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	2	0	0	2
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	1	3
Platelet-derived growth factor receptor beta	0	0	0	1
Adenosine receptor A3	0	5	2	8
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	4	1	7
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	5	3	10
Adenosine receptor A2b	0	1	1	4
Adenosine receptor A2b	0	3	1	5
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	5	3	11
Adenosine receptor A2a	0	4	1	8
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	4	0	5
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	4	0	5
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	4	0	5
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	4	0	5
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	11	0	0	11
chromobox protein homolog 1	10	0	0	10
thyroid hormone receptor beta isoform 2	17	0	0	17
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
geminin	12	0	0	12
lethal factor (plasmid)	5	0	0	5
Polyphenol oxidase 2	0	2	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	2	1	3
Spike glycoprotein	3	0	0	3
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
estrogen receptor 2 (ER beta)	9	0	0	9
peroxisome proliferator-activated receptor delta	7	0	0	7
thyroid stimulating hormone receptor	8	0	0	8
vitamin D3 receptor isoform VDRA	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
phosphopantetheinyl transferase	3	0	0	3
GLS protein	3	0	0	3
farnesoid X nuclear receptor	7	0	0	7
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
DNA polymerase beta	4	0	0	4
DNA polymerase kappa isoform 1	5	0	0	5
muscarinic acetylcholine receptor M1	3	0	0	3
ATP-binding cassette sub-family C member 3	0	7	0	7
Multidrug resistance-associated protein 4	0	7	0	7
Potassium channel subfamily K member 2	0	0	1	1
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase 1	0	5	0	8
Carbonic anhydrase 2	0	7	1	11
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	2	0	2
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	2
Canalicular multispecific organic anion transporter 1	0	6	0	6
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Guanine deaminase	0	1	0	1
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
thioredoxin reductase	6	0	0	6
Microtubule-associated protein tau	6	0	0	6
Bloom syndrome protein isoform 1	1	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	3	0	0	3
neuropeptide S receptor isoform A	4	0	0	4
Prostaglandin G/H synthase 1	0	2	0	2
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	2	3
Prostaglandin G/H synthase 1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	6	0	6
Carbonic anhydrase 4	0	4	0	6
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 6	0	3	0	5
Sucrase-isomaltase, intestinal	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Mu-type opioid receptor	0	4	0	5
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	4	0	5
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 15	0	1	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
15-lipoxygenase, partial	1	0	0	1
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
USP1 protein, partial	7	0	0	7
PINK1	1	0	0	1
thyroid stimulating hormone receptor	10	0	0	10
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
aryl hydrocarbon receptor	8	0	0	8
Caspase-7	2	0	0	2
serine-protein kinase ATM isoform a	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	2	0	0	2
serine/threonine-protein kinase PLK1	2	0	0	2
cytochrome P450 3A4 isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	7	0	1	8
Acetylcholinesterase	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	7	0	1	8
Gamma-aminobutyric acid receptor subunit delta	7	0	1	8
Gamma-aminobutyric acid receptor subunit gamma-2	7	0	1	8
Gamma-aminobutyric acid receptor subunit alpha-5	7	0	1	8
Gamma-aminobutyric acid receptor subunit alpha-3	7	0	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	7	0	1	8
Gamma-aminobutyric acid receptor subunit alpha-2	7	0	1	8
Gamma-aminobutyric acid receptor subunit alpha-4	7	0	1	8
Gamma-aminobutyric acid receptor subunit gamma-3	7	0	1	8
Gamma-aminobutyric acid receptor subunit alpha-6	7	0	1	8
Gamma-aminobutyric acid receptor subunit alpha-1	7	0	1	8
Gamma-aminobutyric acid receptor subunit beta-3	7	0	1	8
Gamma-aminobutyric acid receptor subunit beta-2	7	0	1	8
Carboxylic ester hydrolase	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
GABA theta subunit	7	0	1	8
Gamma-aminobutyric acid receptor subunit epsilon	7	0	1	8
ORF73	0	0	1	1
Chain A, Beta-lactamase	1	0	0	1
Chain A, Ferritin light chain	2	0	0	2
Luciferase	5	0	0	5
interleukin 8	6	0	0	6
endonuclease IV	1	0	0	1
PAX8	0	0	0	1
pregnane X receptor	2	0	0	2
ATAD5 protein, partial	4	0	0	4
Fumarate hydratase	4	0	0	4
PPM1D protein	3	0	0	3
Thrombopoietin	1	0	0	1
Smad3	2	0	0	2
polyprotein	4	0	0	4
67.9K protein	3	0	0	3
glucocerebrosidase	2	0	0	2
cytochrome P450 2D6 isoform 1	2	0	0	2
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C19 precursor	2	0	0	2
cytochrome P450 2C9 precursor	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	1	0	0	1
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	1	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Interferon beta	6	0	0	6
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	1	0	3
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	1	0	1
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	1	0	2
Cytochrome P450 3A4	0	3	0	3
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Histamine H2 receptor	2	0	0	2
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
glp-1 receptor, partial	2	0	0	2
thyrotropin-releasing hormone receptor	3	0	0	3
transcriptional regulator ERG isoform 3	1	0	0	1
Glucocorticoid receptor	0	3	0	4
Sex hormone-binding globulin	0	1	2	3
Progesterone receptor	0	1	0	1
Progesterone receptor	0	1	1	2
Glucocorticoid receptor	0	1	0	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	1	0	1
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	3	2	7
Aromatase	0	4	0	5
Androgen receptor	0	4	1	5
Androgen receptor	0	1	1	2
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
Nuclear factor erythroid 2-related factor 2	0	0	0	1
NFKB1 protein, partial	1	0	0	1
GALC protein	1	0	0	1
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
EWS/FLI fusion protein	5	0	0	5
cytochrome P450 2D6	4	0	0	4
alpha-galactosidase	1	0	0	1
caspase-3	2	0	0	2
D(1A) dopamine receptor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
Solute carrier family 22 member 2	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Alpha-2A adrenergic receptor	0	3	0	3
D(2) dopamine receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	3	0	3
D	0	0	0	1
Retinoic acid receptor RXR-alpha	0	1	3	4
Sodium-dependent noradrenaline transporter	0	4	0	4
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Sodium-dependent serotonin transporter	0	4	0	4
Histamine H1 receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
D(2) dopamine receptor	0	1	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Multidrug and toxin extrusion protein 1	0	3	0	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Trypsin	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Oxoeicosanoid receptor 1	0	1	0	1
G	4	0	0	4
lysosomal alpha-glucosidase preproprotein	2	0	0	2
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Vpr	1	0	0	1
Cytochrome P450 2B1	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Estrogen receptor	0	3	1	4
Glycine receptor subunit alpha-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
Glycine receptor subunit alpha-2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Glycine receptor subunit alpha-3	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Sodium-dependent dopamine transporter	0	2	0	2
Aldehyde oxidase	0	1	0	1
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Inositol hexakisphosphate kinase 1	4	0	0	4
Estrogen receptor beta	0	1	1	2
cytochrome P450 2C9, partial	4	0	0	4
Na(+)/H(+) exchange regulatory cofactor NHE-RF1	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Carbonic anhydrase 12	0	1	0	3
Bile salt export pump	0	1	0	1
Albumin	0	1	0	1
Carbonic anhydrase 3	0	1	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	4
Carbonic anhydrase 7	0	2	0	4
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Carbonic anhydrase 9	0	3	1	6
Carbonic anhydrase 13	0	2	0	4
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Carbonic anhydrase 14	0	1	0	3
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	2
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Steryl-sulfatase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
histone deacetylase 9 isoform 3	2	0	0	2
Chain A, Cruzipain	1	0	0	1
G1/S-specific cyclin-E1	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
Tyrosine-protein kinase ZAP-70	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Protein-tyrosine kinase 2-beta	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Genome polyprotein	0	1	0	1
Neuraminidase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Dipeptidyl peptidase 4	0	1	0	1
Substance-P receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
apical membrane antigen 1, AMA1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
acid sphingomyelinase	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (91)

Protein Targets (575)

Triploid

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (91)

Drugs Studied (82)

Protein Targets (575)