Page last updated: 2024-12-09

2,4-hexadienal

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,4-hexadienal: RN given refers to compound with no isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

hexadienal : An enal that is hexadiene carrying an oxo group at position 1. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

(E,E)-2,4-hexadienal : A hexadienal that is hexanal with trans double bonds at positions 2 and 4. It is found in tomatoes, kiwi fruit, mangoes, potato chips, herbs and spices. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID637564
CHEMBL ID1576086
CHEBI ID82334
MeSH IDM0212528

Synonyms (75)

Synonym
2,4-hexadienal (89% trans,trans-, 11% cis,trans-)
80466-34-8
2,4-hexadienal
sorbaldehyde
2,4-hexadienal, (e,e)-
142-83-6
(2e,4e)-hexa-2,4-dienal
hexa-2,4-dienal
NCGC00090786-01
brn 1698401
trans,trans-2,4-hexadienal
(e,e)-2,4-hexadien-1-al
3-propyleneacrolein
2,4-hexadienal, (2e,4e)-
fema no. 3429
einecs 205-564-3
ai3-31142
trans,trans-2,4-hexadien-1-al
ccris 4030
2-propyleneacrolein
2,4-hexadienal, trans,trans-
1,3-pentadiene-1-carboxaldehyde
hsdb 7239
trans,trans-2,4-hexadienal, >=95%
LMFA06000006
sorbic aldehyde
trans,trans-2,4-hexadienal, 95%
hexadienal
H0581
A807974
NCGC00090786-03
NCGC00090786-02
(e,e)-2,4-hexadienal
unii-878k4i6n7t
878k4i6n7t ,
4-01-00-03545 (beilstein handbook reference)
C19249
tox21_200834
(2e,4e)-2,4-hexadienal
dtxsid2025391 ,
cas-142-83-6
NCGC00258388-01
dtxcid205391
73506-81-7
AKOS015915466
chebi:82334 ,
CHEMBL1576086
2,4-hexadienal [hsdb]
trans,trans-2,4-hexadienal [fhfi]
(2e,4e) hexadienal
trans-2,4-hexadienal
2,4-(e-e)-hexadienal
trans,trans-hexa-2,4-dienal
n-hex-2,4-dienal, trans,trans-
(2e,4e)-hexadienal
2,4-(e,e)-hexadienal
(e)-2,(e)-4-hexadienal
e,e-2,4-hexadienal
2,4-hexadien-1-al, (e,e)-
t,t-2,4-hexadienal
hexa-2,4-dienal, (e,e)-
(2e,4e)-2,4-hexadienal #
(e,e)-hexa-2,4-dienal
mfcd00007004
trans,trans-2,4-hexadienal, analytical standard
2,4-hexadienal, predominantly trans,trans
J-007704
Q27155883
hexadienal (2e,4e-)
D90909
A929664
EN300-113666
2,4-hexadienal (mixture of isomers)
CS-0067535
HY-W068035

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Tissues and plasma from dosed rats were examined for malondialdehyde and glutathione concentrations, and DNA adducts were characterized in liver and forestomach samples from dosed rats and mice."( NTP toxicology and carcinogensis Studies of 2,4-hexadienal (89% trans,trans isomer, CAS No. 142-83-6; 11% cis,trans isomer) (Gavage Studies).
, 2003
)
0.58
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
flavouring agentA food additive that is used to added improve the taste or odour of a food.
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
polyunsaturated fatty aldehydeAny fatty aldehyde containing more than one double or triple bond located at any position in the aliphatic chain.
hexadienalAn enal that is hexadiene carrying an oxo group at position 1.
volatile organic compoundAny organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (15)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency61.88300.006038.004119,952.5996AID1159521; AID1159523
GLI family zinc finger 3Homo sapiens (human)Potency51.83250.000714.592883.7951AID1259369; AID1259392
AR proteinHomo sapiens (human)Potency19.79240.000221.22318,912.5098AID743035; AID743036; AID743063
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency25.11890.011212.4002100.0000AID1030
retinoid X nuclear receptor alphaHomo sapiens (human)Potency50.11870.000817.505159.3239AID588546
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency60.69570.001530.607315,848.9004AID1224841
estrogen nuclear receptor alphaHomo sapiens (human)Potency61.20760.000229.305416,493.5996AID743075
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency28.18380.001019.414170.9645AID588536
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency50.11870.023723.228263.5986AID588541
activating transcription factor 6Homo sapiens (human)Potency43.33700.143427.612159.8106AID1159516
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency30.68030.057821.109761.2679AID1159528
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.07080.010039.53711,122.0200AID588547
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency40.69770.000627.21521,122.0200AID651741; AID743202; AID743219
Cellular tumor antigen p53Homo sapiens (human)Potency68.10160.002319.595674.0614AID651631
Nuclear receptor ROR-gammaHomo sapiens (human)Potency33.49150.026622.448266.8242AID651802
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (134)

Processvia Protein(s)Taxonomy
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycle G2/M phase transitionCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
ER overload responseCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
mitophagyCellular tumor antigen p53Homo sapiens (human)
in utero embryonic developmentCellular tumor antigen p53Homo sapiens (human)
somitogenesisCellular tumor antigen p53Homo sapiens (human)
release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
hematopoietic progenitor cell differentiationCellular tumor antigen p53Homo sapiens (human)
T cell proliferation involved in immune responseCellular tumor antigen p53Homo sapiens (human)
B cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
T cell lineage commitmentCellular tumor antigen p53Homo sapiens (human)
response to ischemiaCellular tumor antigen p53Homo sapiens (human)
nucleotide-excision repairCellular tumor antigen p53Homo sapiens (human)
double-strand break repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
protein import into nucleusCellular tumor antigen p53Homo sapiens (human)
autophagyCellular tumor antigen p53Homo sapiens (human)
DNA damage responseCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorCellular tumor antigen p53Homo sapiens (human)
transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
Ras protein signal transductionCellular tumor antigen p53Homo sapiens (human)
gastrulationCellular tumor antigen p53Homo sapiens (human)
neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of neuroblast proliferationCellular tumor antigen p53Homo sapiens (human)
protein localizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA replicationCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell population proliferationCellular tumor antigen p53Homo sapiens (human)
determination of adult lifespanCellular tumor antigen p53Homo sapiens (human)
mRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
rRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
response to salt stressCellular tumor antigen p53Homo sapiens (human)
response to inorganic substanceCellular tumor antigen p53Homo sapiens (human)
response to X-rayCellular tumor antigen p53Homo sapiens (human)
response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
positive regulation of gene expressionCellular tumor antigen p53Homo sapiens (human)
cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic processCellular tumor antigen p53Homo sapiens (human)
glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
viral processCellular tumor antigen p53Homo sapiens (human)
glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
cerebellum developmentCellular tumor antigen p53Homo sapiens (human)
negative regulation of cell growthCellular tumor antigen p53Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathwayCellular tumor antigen p53Homo sapiens (human)
mitotic G1 DNA damage checkpoint signalingCellular tumor antigen p53Homo sapiens (human)
negative regulation of telomere maintenance via telomeraseCellular tumor antigen p53Homo sapiens (human)
T cell differentiation in thymusCellular tumor antigen p53Homo sapiens (human)
tumor necrosis factor-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
regulation of tissue remodelingCellular tumor antigen p53Homo sapiens (human)
cellular response to UVCellular tumor antigen p53Homo sapiens (human)
multicellular organism growthCellular tumor antigen p53Homo sapiens (human)
positive regulation of mitochondrial membrane permeabilityCellular tumor antigen p53Homo sapiens (human)
cellular response to glucose starvationCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of apoptotic processCellular tumor antigen p53Homo sapiens (human)
entrainment of circadian clock by photoperiodCellular tumor antigen p53Homo sapiens (human)
mitochondrial DNA repairCellular tumor antigen p53Homo sapiens (human)
regulation of DNA damage response, signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
transcription initiation-coupled chromatin remodelingCellular tumor antigen p53Homo sapiens (human)
negative regulation of proteolysisCellular tumor antigen p53Homo sapiens (human)
negative regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of DNA-templated transcriptionCellular tumor antigen p53Homo sapiens (human)
positive regulation of RNA polymerase II transcription preinitiation complex assemblyCellular tumor antigen p53Homo sapiens (human)
positive regulation of transcription by RNA polymerase IICellular tumor antigen p53Homo sapiens (human)
response to antibioticCellular tumor antigen p53Homo sapiens (human)
fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
negative regulation of fibroblast proliferationCellular tumor antigen p53Homo sapiens (human)
circadian behaviorCellular tumor antigen p53Homo sapiens (human)
bone marrow developmentCellular tumor antigen p53Homo sapiens (human)
embryonic organ developmentCellular tumor antigen p53Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylationCellular tumor antigen p53Homo sapiens (human)
protein stabilizationCellular tumor antigen p53Homo sapiens (human)
negative regulation of helicase activityCellular tumor antigen p53Homo sapiens (human)
protein tetramerizationCellular tumor antigen p53Homo sapiens (human)
chromosome organizationCellular tumor antigen p53Homo sapiens (human)
neuron apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of cell cycleCellular tumor antigen p53Homo sapiens (human)
hematopoietic stem cell differentiationCellular tumor antigen p53Homo sapiens (human)
negative regulation of glial cell proliferationCellular tumor antigen p53Homo sapiens (human)
type II interferon-mediated signaling pathwayCellular tumor antigen p53Homo sapiens (human)
cardiac septum morphogenesisCellular tumor antigen p53Homo sapiens (human)
positive regulation of programmed necrotic cell deathCellular tumor antigen p53Homo sapiens (human)
protein-containing complex assemblyCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressCellular tumor antigen p53Homo sapiens (human)
thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of thymocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
necroptotic processCellular tumor antigen p53Homo sapiens (human)
cellular response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
cellular response to xenobiotic stimulusCellular tumor antigen p53Homo sapiens (human)
cellular response to ionizing radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to gamma radiationCellular tumor antigen p53Homo sapiens (human)
cellular response to UV-CCellular tumor antigen p53Homo sapiens (human)
stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
signal transduction by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
cellular response to actinomycin DCellular tumor antigen p53Homo sapiens (human)
positive regulation of release of cytochrome c from mitochondriaCellular tumor antigen p53Homo sapiens (human)
cellular senescenceCellular tumor antigen p53Homo sapiens (human)
replicative senescenceCellular tumor antigen p53Homo sapiens (human)
oxidative stress-induced premature senescenceCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
oligodendrocyte apoptotic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of execution phase of apoptosisCellular tumor antigen p53Homo sapiens (human)
negative regulation of mitophagyCellular tumor antigen p53Homo sapiens (human)
regulation of mitochondrial membrane permeability involved in apoptotic processCellular tumor antigen p53Homo sapiens (human)
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorCellular tumor antigen p53Homo sapiens (human)
positive regulation of miRNA transcriptionCellular tumor antigen p53Homo sapiens (human)
negative regulation of G1 to G0 transitionCellular tumor antigen p53Homo sapiens (human)
negative regulation of miRNA processingCellular tumor antigen p53Homo sapiens (human)
negative regulation of glucose catabolic process to lactate via pyruvateCellular tumor antigen p53Homo sapiens (human)
negative regulation of pentose-phosphate shuntCellular tumor antigen p53Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hypoxiaCellular tumor antigen p53Homo sapiens (human)
regulation of fibroblast apoptotic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
positive regulation of reactive oxygen species metabolic processCellular tumor antigen p53Homo sapiens (human)
negative regulation of stem cell proliferationCellular tumor antigen p53Homo sapiens (human)
positive regulation of cellular senescenceCellular tumor antigen p53Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathwayCellular tumor antigen p53Homo sapiens (human)
negative regulation of transcription by RNA polymerase IINuclear receptor ROR-gammaHomo sapiens (human)
xenobiotic metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
regulation of glucose metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
regulation of steroid metabolic processNuclear receptor ROR-gammaHomo sapiens (human)
intracellular receptor signaling pathwayNuclear receptor ROR-gammaHomo sapiens (human)
circadian regulation of gene expressionNuclear receptor ROR-gammaHomo sapiens (human)
cellular response to sterolNuclear receptor ROR-gammaHomo sapiens (human)
positive regulation of circadian rhythmNuclear receptor ROR-gammaHomo sapiens (human)
regulation of fat cell differentiationNuclear receptor ROR-gammaHomo sapiens (human)
positive regulation of DNA-templated transcriptionNuclear receptor ROR-gammaHomo sapiens (human)
adipose tissue developmentNuclear receptor ROR-gammaHomo sapiens (human)
T-helper 17 cell differentiationNuclear receptor ROR-gammaHomo sapiens (human)
regulation of transcription by RNA polymerase IINuclear receptor ROR-gammaHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (38)

Processvia Protein(s)Taxonomy
transcription cis-regulatory region bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
cis-regulatory region sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
core promoter sequence-specific DNA bindingCellular tumor antigen p53Homo sapiens (human)
TFIID-class transcription factor complex bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specificCellular tumor antigen p53Homo sapiens (human)
protease bindingCellular tumor antigen p53Homo sapiens (human)
p53 bindingCellular tumor antigen p53Homo sapiens (human)
DNA bindingCellular tumor antigen p53Homo sapiens (human)
chromatin bindingCellular tumor antigen p53Homo sapiens (human)
DNA-binding transcription factor activityCellular tumor antigen p53Homo sapiens (human)
mRNA 3'-UTR bindingCellular tumor antigen p53Homo sapiens (human)
copper ion bindingCellular tumor antigen p53Homo sapiens (human)
protein bindingCellular tumor antigen p53Homo sapiens (human)
zinc ion bindingCellular tumor antigen p53Homo sapiens (human)
enzyme bindingCellular tumor antigen p53Homo sapiens (human)
receptor tyrosine kinase bindingCellular tumor antigen p53Homo sapiens (human)
ubiquitin protein ligase bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase regulator activityCellular tumor antigen p53Homo sapiens (human)
ATP-dependent DNA/DNA annealing activityCellular tumor antigen p53Homo sapiens (human)
identical protein bindingCellular tumor antigen p53Homo sapiens (human)
histone deacetylase bindingCellular tumor antigen p53Homo sapiens (human)
protein heterodimerization activityCellular tumor antigen p53Homo sapiens (human)
protein-folding chaperone bindingCellular tumor antigen p53Homo sapiens (human)
protein phosphatase 2A bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor bindingCellular tumor antigen p53Homo sapiens (human)
14-3-3 protein bindingCellular tumor antigen p53Homo sapiens (human)
MDM2/MDM4 family protein bindingCellular tumor antigen p53Homo sapiens (human)
disordered domain specific bindingCellular tumor antigen p53Homo sapiens (human)
general transcription initiation factor bindingCellular tumor antigen p53Homo sapiens (human)
molecular function activator activityCellular tumor antigen p53Homo sapiens (human)
promoter-specific chromatin bindingCellular tumor antigen p53Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA bindingNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specificNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specificNuclear receptor ROR-gammaHomo sapiens (human)
DNA-binding transcription factor activityNuclear receptor ROR-gammaHomo sapiens (human)
protein bindingNuclear receptor ROR-gammaHomo sapiens (human)
oxysterol bindingNuclear receptor ROR-gammaHomo sapiens (human)
zinc ion bindingNuclear receptor ROR-gammaHomo sapiens (human)
ligand-activated transcription factor activityNuclear receptor ROR-gammaHomo sapiens (human)
sequence-specific double-stranded DNA bindingNuclear receptor ROR-gammaHomo sapiens (human)
nuclear receptor activityNuclear receptor ROR-gammaHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (19)

Processvia Protein(s)Taxonomy
nuclear bodyCellular tumor antigen p53Homo sapiens (human)
nucleusCellular tumor antigen p53Homo sapiens (human)
nucleoplasmCellular tumor antigen p53Homo sapiens (human)
replication forkCellular tumor antigen p53Homo sapiens (human)
nucleolusCellular tumor antigen p53Homo sapiens (human)
cytoplasmCellular tumor antigen p53Homo sapiens (human)
mitochondrionCellular tumor antigen p53Homo sapiens (human)
mitochondrial matrixCellular tumor antigen p53Homo sapiens (human)
endoplasmic reticulumCellular tumor antigen p53Homo sapiens (human)
centrosomeCellular tumor antigen p53Homo sapiens (human)
cytosolCellular tumor antigen p53Homo sapiens (human)
nuclear matrixCellular tumor antigen p53Homo sapiens (human)
PML bodyCellular tumor antigen p53Homo sapiens (human)
transcription repressor complexCellular tumor antigen p53Homo sapiens (human)
site of double-strand breakCellular tumor antigen p53Homo sapiens (human)
germ cell nucleusCellular tumor antigen p53Homo sapiens (human)
chromatinCellular tumor antigen p53Homo sapiens (human)
transcription regulator complexCellular tumor antigen p53Homo sapiens (human)
protein-containing complexCellular tumor antigen p53Homo sapiens (human)
nucleusNuclear receptor ROR-gammaHomo sapiens (human)
nucleoplasmNuclear receptor ROR-gammaHomo sapiens (human)
nuclear bodyNuclear receptor ROR-gammaHomo sapiens (human)
chromatinNuclear receptor ROR-gammaHomo sapiens (human)
nucleusNuclear receptor ROR-gammaHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (36)

Assay IDTitleYearJournalArticle
AID1102755Antimicrobial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as growth inhibition rate at 0.025 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102774Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as growth inhibition rate at 6.8 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102709Antimicrobial activity against Listeria monocytogenes ATCC 19111 assessed as growth inhibition rate at 0.025 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102778Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as growth inhibition rate at 0.025 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102752Antimicrobial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as growth inhibition rate at 0.68 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102683Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition rate at 0.68 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102920Antimicrobial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as growth inhibition rate at 3.4 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102889Antimicrobial activity against Vibrio parahaemolyticus ATCC 33844 assessed as growth inhibition rate at 3.4 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102663Antimicrobial activity against Escherichia coli O157:H7 ATCC 43894 assessed as growth inhibition rate at 0.025 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102730Antimicrobial activity against Vibrio parahaemolyticus ATCC 33844 assessed as growth inhibition rate at 0.12 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102729Antimicrobial activity against Vibrio parahaemolyticus ATCC 33844 assessed as growth inhibition rate at 0.68 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102775Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as growth inhibition rate at 0.68 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102661Antimicrobial activity against Escherichia coli O157:H7 ATCC 43894 assessed as growth inhibition rate at 0.12 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102731Antimicrobial activity against Vibrio parahaemolyticus ATCC 33844 assessed as growth inhibition rate at 0.05 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102662Antimicrobial activity against Escherichia coli O157:H7 ATCC 43894 assessed as growth inhibition rate at 0.05 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102728Antimicrobial activity against Vibrio parahaemolyticus ATCC 33844 assessed as growth inhibition rate at 6.8 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102753Antimicrobial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as growth inhibition rate at 0.12 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102857Antimicrobial activity against Listeria monocytogenes ATCC 19111 assessed as growth inhibition rate at 3.4 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102660Antimicrobial activity against Escherichia coli O157:H7 ATCC 43894 assessed as growth inhibition rate at 0.68 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102686Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition rate at 0.025 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102708Antimicrobial activity against Listeria monocytogenes ATCC 19111 assessed as growth inhibition rate at 0.05 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102751Antimicrobial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as growth inhibition rate at 6.8 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102732Antimicrobial activity against Vibrio parahaemolyticus ATCC 33844 assessed as growth inhibition rate at 0.025 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102682Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition rate at 6.8 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102706Antimicrobial activity against Listeria monocytogenes ATCC 19111 assessed as growth inhibition rate at 0.68 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102705Antimicrobial activity against Listeria monocytogenes ATCC 19111 assessed as growth inhibition rate at 6.8 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102684Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition rate at 0.12 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102796Antimicrobial activity against Escherichia coli O157:H7 ATCC 43894 assessed as growth inhibition rate at 3.4 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102777Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as growth inhibition rate at 0.05 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102659Antimicrobial activity against Escherichia coli O157:H7 ATCC 43894 assessed as growth inhibition rate at 6.8 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102827Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition rate at 3.4 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102707Antimicrobial activity against Listeria monocytogenes ATCC 19111 assessed as growth inhibition rate at 0.12 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102776Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as growth inhibition rate at 0.12 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102951Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as growth inhibition rate at 3.4 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102754Antimicrobial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as growth inhibition rate at 0.05 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
AID1102685Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition rate at 0.05 mg/l after 72 hr by spectrophotometry2004Journal of agricultural and food chemistry, Feb-25, Volume: 52, Issue:4
Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's8 (61.54)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.82 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.27 (4.65)
Search Engine Demand Index34.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]