Roles > farnesoid X receptor agonist
Page last updated: 2024-08-05 15:42:55
farnesoid X receptor agonist
An agonist that binds to and activates farnesoid X receptors
ChEBI ID: 132972
Members (1)
| Member | Definition | Class |
|---|
| obeticholic acid | A dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis. | obeticholic acid |
Research
Studies (339)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (4.42) | 29.6817 |
| 2010's | 222 (65.49) | 24.3611 |
| 2020's | 102 (30.09) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 27 (7.76%) | 5.53% |
| Reviews | 106 (30.46%) | 6.00% |
| Case Studies | 3 (0.86%) | 4.05% |
| Observational | 2 (0.57%) | 0.25% |
| Other | 210 (60.34%) | 84.16% |
Protein Targets (6)
Activation Measurements