defibrotide has been researched along with Abdominal-Pain* in 1 studies
1 other study(ies) available for defibrotide and Abdominal-Pain
| Article | Year |
|---|---|
Defibrotide for the Treatment of Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in 2 Pediatric Patients.
The pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 infection is a severe complication of coronavirus disease 2019. Since impaired coagulation and thrombosis/endotheliitis are suspected pathomechanisms, we treated 2 patients with defibrotide, a profibrinolytic, antithrombotic, antiinflammatory oligonucleotide. Symptoms resolved during treatment. Moreover, coagulation parameters indicating hypofibrinolysis and complement activation normalized. The pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 infection is a severe complication of coronavirus disease 2019. Since impaired coagulation and thrombosis/endotheliitis are suspected pathomechanisms, 2 patients received defibrotide, a profibrinolytic, antithrombotic, antiinflammatory oligonucleotide. Symptoms resolved and hypofibrinolysis/complement activation normalized during treatment. Topics: Abdominal Pain; Adolescent; Betacoronavirus; Blood Coagulation Factors; Child; Coronavirus Infections; COVID-19; Female; Fever; Humans; Pandemics; Platelet Aggregation Inhibitors; Pneumonia, Viral; Polydeoxyribonucleotides; SARS-CoV-2; Systemic Inflammatory Response Syndrome; T-Lymphocytes | 2020 |