defibrotide has been researched along with Necrosis* in 1 studies
1 other study(ies) available for defibrotide and Necrosis
Article | Year |
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Use of defibrotide in the treatment of acute myocardial infarction.
The results of this preliminary clinical trial confirm the thrombolytic effect of defibrotide demonstrated in preclinical models; demonstrate the positive influence of the product on the natural history of early AMI; suggest that the optimal dosage range should include not less than 1.6 gm of defibrotide during the first hour of treatment; and justify further commitment in the study of defibrotide also beyond the scope of treating AMI. Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Myocardial Infarction; Myocardial Reperfusion; Necrosis; Polydeoxyribonucleotides | 1989 |