Sertoli Cell Tumor

Gonadal neoplasm composed entirely of SERTOLI CELLS or may have a component of GRANULOSA CELLS. Some of the Sertoli cell tumors produce ESTROGEN or ANDROGENS, but seldom in sufficient quantity to cause clinical symptoms such as FEMINIZATION or masculinization (VIRILISM).

Synonym
Sertoli Cell Tumor

Excerpt	Reference
"Ovarian oxyphilic Sertoli cell tumor is a rare neoplasm (only three cases were reported in literature)."	( Morelli, L; Piscioli, F; Pusiol, T, 2006)
"Malignant sertoli cell tumor is a rare disease and only a few cases have been described previously."	( Gotoh, M; Hattori, R; Komatsu, T; Matsukawa, Y; Sassa, N; Yamamoto, T; Yoshikawa, Y; Yoshino, Y, 2008)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	74 (56.06)	23.3326
1990's	18 (13.64)	12.5806
2000's	24 (18.18)	18.1394
2010's	13 (9.85)	28.8240
2020's	3 (2.27)	9.53

Drug	Relationship Strength	Studies
chlorine	low	1
phenol	low	1
pyridoxal phosphate	low	1
uracil	low	1
altretamine	low	1
anastrozole	low	4
flutamide	low	1
guaifenesin	low	1
letrozole	low	1
mitotane	low	1
activins	low	2
phenylbutazone	low	1
estriol	low	2
thyroxine	low	1
penicillamine	low	1
estrone	low	4
androsterone	low	1
etiocholanolone	low	1
dehydroepiandrosterone	low	9
penicillin g	low	1
diethylnitrosamine	low	1
dimethylnitrosamine	low	1
androstenedione	low	7
norethindrone	low	1
17-alpha-hydroxyprogesterone	low	1
medroxyprogesterone acetate	low	1
dichlorodiphenyldichloroethane	low	1
bisphenol a	low	1
4-vinyl-1-cyclohexene dioxide	low	1
benzathine	low	1
pregnenolone	low	3
chlormadinone acetate	low	1
hematoxylin	low	1
medroxyprogesterone	low	1
dihydrotestosterone	low	2
eosine yellowish-(ys)	low	1
dehydroepiandrosterone sulfate	low	1
ethylnitrosourea	low	5
propylnitrosourea	low	1
testolactone	low	2
cadmium	low	2
camptothecin	low	1
cadmium chloride	low	2
transferrin	low	1
buserelin	low	1
irinotecan	low	1
triazoles	low	3
fluorodeoxyglucose f18	low	1
17-alpha-hydroxypregnenolone	low	1
estrone-3-glucuronide	low	1
glycogen	low	1
dactinomycin	low	3
bromochloroacetic acid	low	14
isomethyleugenol	low	1
tamoxifen	low	1
17-ketosteroids	low	6
cyproterone	low	1
gadolinium dtpa	low	1
mart-1 antigen	low	2
ribose	low	1
19-iodocholesterol	low	1
cyclin d1	low	1
nedaplatin	low	1
phosphorus radioisotopes	low	1

Protein Targets (631)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Cruzipain	5	0	0	5
IDH1	3	0	0	3
DNA polymerase iota isoform a (long)	9	0	0	9
geminin	18	0	0	18
Sex hormone-binding globulin	0	1	12	13
acetylcholinesterase	6	0	0	6
pregnane X receptor	7	0	0	7
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
TDP1 protein	23	0	0	23
GLI family zinc finger 3	24	0	0	24
Microtubule-associated protein tau	8	0	0	8
AR protein	26	0	0	26
progesterone receptor	20	0	0	20
glucocorticoid receptor [Homo sapiens]	22	0	0	22
retinoic acid nuclear receptor alpha variant 1	21	0	0	21
retinoid X nuclear receptor alpha	18	0	0	18
estrogen-related nuclear receptor alpha	23	0	0	23
farnesoid X nuclear receptor	13	0	0	13
pregnane X nuclear receptor	19	0	0	19
estrogen nuclear receptor alpha	30	0	0	30
G	14	0	0	14
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
arylsulfatase A	4	0	0	4
euchromatic histone-lysine N-methyltransferase 2	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	18	0	0	18
activating transcription factor 6	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
chromobox protein homolog 1	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 1	19	0	0	19
survival motor neuron protein isoform d	8	0	0	8
histone acetyltransferase KAT2A isoform 1	5	0	0	5
lamin isoform A-delta10	11	0	0	11
Voltage-dependent calcium channel gamma-2 subunit	13	0	0	13
Interferon beta	18	0	0	18
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Glucocorticoid receptor	0	13	1	15
Glycine receptor subunit alpha-1	0	12	0	12
Corticosteroid-binding globulin	0	9	0	9
Adenosine receptor A3	0	6	0	6
Replicase polyprotein 1ab	0	1	1	2
Androgen receptor	0	24	1	25
Alpha-1B adrenergic receptor	0	6	0	6
Glutamate receptor 2	13	0	0	13
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Mitogen-activated protein kinase 3	0	1	0	1
Alpha-1A adrenergic receptor	0	6	0	6
Sodium-dependent dopamine transporter	0	8	0	8
TAR DNA-binding protein 43	7	0	0	7
Inositol hexakisphosphate kinase 1	14	0	0	14
cytochrome P450 2C9, partial	14	0	0	14
ATP-dependent phosphofructokinase	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
thyroid hormone receptor beta isoform a	9	0	0	9
Cellular tumor antigen p53	13	0	0	13
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
thioredoxin reductase	7	0	0	7
regulator of G-protein signaling 4	6	0	0	6
EWS/FLI fusion protein	7	0	0	7
nonstructural protein 1	6	0	0	6
alpha-galactosidase	4	0	0	4
Bloom syndrome protein isoform 1	7	0	0	7
D(1A) dopamine receptor	4	0	0	4
fMet-Leu-Phe receptor	0	2	0	2
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
muscarinic acetylcholine receptor M1	3	0	0	3
Bile salt export pump	0	14	0	14
Cytochrome P450 1A2	0	1	0	1
CREB-binding protein	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	14	0	0	14
thyroid hormone receptor beta isoform 2	19	0	0	19
ATP-binding cassette sub-family C member 3	0	5	0	5
Multidrug resistance-associated protein 4	0	6	0	7
Aromatase	0	9	0	12
Cytochrome P450 2C9	0	2	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
Spike glycoprotein	7	0	1	8
Canalicular multispecific organic anion transporter 1	0	5	0	5
interleukin 8	6	0	0	6
RAR-related orphan receptor gamma	20	0	0	20
Smad3	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	11	0	0	11
estrogen receptor 2 (ER beta)	14	0	0	14
peroxisome proliferator-activated receptor delta	15	0	0	15
peroxisome proliferator activated receptor gamma	16	0	0	16
Histone H2A.x	8	0	0	8
Caspase-7	5	0	0	5
peripheral myelin protein 22 isoform 1	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	5	0	0	5
mitogen-activated protein kinase 1	7	0	0	7
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	6	0	0	6
peripheral myelin protein 22	8	0	0	8
muscleblind-like protein 1 isoform 1	4	0	0	4
neuropeptide S receptor isoform A	4	0	0	4
Beta-glucuronidase	0	2	0	2
Cholinesterase	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	3	0	3
Alpha-synuclein	4	3	0	7
Nuclear receptor ROR-gamma	10	0	0	10
Chain A, retinol dehydratase	0	1	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	12	1	0	13
Glucose-6-phosphate 1-dehydrogenase	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	12	1	0	13
Gamma-aminobutyric acid receptor subunit delta	12	1	0	13
Gamma-aminobutyric acid receptor subunit gamma-2	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-5	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-3	12	1	0	13
Gamma-aminobutyric acid receptor subunit gamma-1	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-2	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-4	12	1	0	13
Gamma-aminobutyric acid receptor subunit gamma-3	12	1	0	13
Gamma-aminobutyric acid receptor subunit alpha-6	12	1	0	13
Solute carrier organic anion transporter family member 1A1	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	12	1	0	13
Gamma-aminobutyric acid receptor subunit beta-3	12	1	0	13
Gamma-aminobutyric acid receptor subunit beta-2	12	1	0	13
G-protein coupled bile acid receptor 1	0	0	5	5
GABA theta subunit	12	1	0	13
Gamma-aminobutyric acid receptor subunit epsilon	12	1	0	13
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
DNA polymerase kappa isoform 1	3	0	0	3
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Luciferase	3	0	0	3
glp-1 receptor, partial	3	0	0	3
GALC protein	3	0	0	3
GLS protein	3	0	0	3
caspase 7, apoptosis-related cysteine protease	4	0	0	4
thyroid stimulating hormone receptor	7	0	0	7
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
cytochrome P450 2D6	5	0	0	5
caspase-3	4	0	0	4
aryl hydrocarbon receptor	8	0	0	8
thyroid stimulating hormone receptor	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	10	0	0	10
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
cytochrome P450 3A4 isoform 1	12	0	0	12
GTPase KRas	0	0	1	1
Estrogen receptor	0	12	4	18
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	6	0	6
Androgen receptor	0	7	4	13
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Sodium-dependent noradrenaline transporter	0	6	0	6
Sodium-dependent serotonin transporter	0	12	0	12
5-hydroxytryptamine receptor 6	0	8	0	8
Estrogen-related receptor gamma	0	2	0	2
GTP-binding protein Rheb	0	0	1	1
Estrogen receptor beta	0	5	4	10
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
Chain A, Ferritin light chain	5	0	0	5
DNA topoisomerase	0	1	0	1
15-lipoxygenase, partial	4	0	0	4
ATAD5 protein, partial	5	0	0	5
Fumarate hydratase	4	0	0	4
NFKB1 protein, partial	2	0	0	2
PPM1D protein	5	0	0	5
Thrombopoietin	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
polyprotein	4	0	0	4
67.9K protein	5	0	0	5
glucocerebrosidase	3	0	0	3
putative alpha-glucosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C19 precursor	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
huntingtin isoform 2	3	0	0	3
ras-related protein Rab-9A	2	0	0	2
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
M-phase phosphoprotein 8	5	0	0	5
relaxin receptor 1 isoform 1	1	0	0	1
lethal factor (plasmid)	6	0	0	6
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Histone deacetylase 3	0	1	0	1
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	0	0	1
DNA ligase	0	1	0	1
Integrin beta-3	3	0	0	3
Integrin alpha-IIb	3	0	0	3
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	1	1	7
DNA topoisomerase 2-alpha	0	1	0	1
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	8	0	8
Type-2 restriction enzyme HindIII	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Histone deacetylase 4	0	1	0	1
Ribonuclease pancreatic	0	1	0	1
Inositol monophosphatase 1	3	0	0	3
DNA topoisomerase 2-beta	0	0	0	1
DNA topoisomerase 1	0	1	0	2
Histone deacetylase 1	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Integrase	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	4	0	4
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 15	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
thioredoxin glutathione reductase	2	0	0	2
vitamin D3 receptor isoform VDRA	8	0	0	8
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
transcriptional regulator ERG isoform 3	4	0	0	4
Cytochrome P450 2C19	0	2	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
USP1 protein, partial	7	0	0	7
RAD51	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
ATP-dependent translocase ABCB1	0	2	1	4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	1	0	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
ATPase family AAA domain-containing protein 5	4	0	0	4
Ataxin-2	4	0	0	4
heat shock protein beta-1	4	0	0	4
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Steryl-sulfatase	0	2	0	3
Multidrug resistance-associated protein 1	0	0	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
Peroxisome proliferator-activated receptor alpha	2	0	0	2
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
thyrotropin-releasing hormone receptor	2	0	0	2
Plasma kallikrein	0	1	0	1
Progesterone receptor	0	1	0	1
Progesterone receptor	0	6	4	10
Glucocorticoid receptor	0	1	0	1
Mineralocorticoid receptor	0	2	0	2
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	1	2	3
Mineralocorticoid receptor	0	1	0	1
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	0	1
ORF73	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
Olfactory receptor 51E2	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
endonuclease IV	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Rap guanine nucleotide exchange factor 3	4	0	0	4
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	0	1	1
Mu-type opioid receptor	0	0	1	1
Cytochrome P450 1B1	0	1	0	1
Ghrelin O-acyltransferase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain A, Beta-lactamase	6	0	0	6
ClpP	1	0	0	1
Guanine nucleotide-binding protein G	4	0	0	4
cytochrome P450 2C9 precursor	2	0	0	2
Cocaine esterase	0	1	0	2
Bile salt export pump	0	2	0	2
Arylacetamide deacetylase	0	0	0	1
Histamine H2 receptor	4	0	0	4
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
flap endonuclease 1	2	0	0	2
Chain E, Fibrin beta chain	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	1	0	0	1
Mcl-1	0	1	0	1
phosphopantetheinyl transferase	4	0	0	4
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
apical membrane antigen 1, AMA1	3	0	0	3
hypothetical protein, conserved	1	0	0	1
luciferase	1	0	0	1
pyruvate kinase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
intestinal alkaline phosphatase precursor	0	0	1	1
DNA polymerase beta	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
DNA polymerase eta isoform 1	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Vif	0	1	0	1
Tat	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Pyruvate kinase PKM	0	1	0	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
phosphoglycerate kinase	1	0	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	2
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M4	0	4	0	4
Cytochrome P450 3A4	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Acetylcholinesterase	0	2	0	2
Liver carboxylesterase 1	0	0	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
PINK1	2	0	0	2
Parkin	3	0	0	3
Histamine H2 receptor	0	4	0	4
5-hydroxytryptamine receptor 1B	0	3	0	3
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Alpha-2A adrenergic receptor	0	4	0	4
Rap guanine nucleotide exchange factor 4	1	0	0	1
Estrogen receptor	0	0	2	3
Estrogen receptor beta	0	0	2	3
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
streptokinase A precursor	0	0	2	2
Solute carrier family 22 member 6	0	1	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase VIM-1	0	0	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Polyphenol oxidase 2	0	0	0	1
Carbonic anhydrase 12	0	1	0	1
Endolysin	0	0	1	1
Carbonic anhydrase 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase 6	0	2	0	2
Adenosine receptor A1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	0	1	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
Estrogen receptor 1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	1	0	1
P2X purinoceptor 4	0	0	1	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
cytochrome P450 2D6 isoform 1	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
5-hydroxytryptamine receptor 4	0	2	0	2
Serine/threonine-protein kinase D3	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Procathepsin L	0	0	1	1
Muscarinic acetylcholine receptor M2	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Protein kinase C alpha type	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Substance-P receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Adenosine receptor A1	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Protein cereblon	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (132)

Protein Targets (631)

Sertoli Cell Tumor

Synonyms(1)

Research Excerpts

Overview

Research

Studies (132)

Drugs Studied (77)

Protein Targets (631)