Page last updated: 2024-09-27

Ciguatera Poisoning

Poisoning caused by ingestion of SEAFOOD containing microgram levels of CIGUATOXINS. The poisoning is characterized by gastrointestinal, neurological and cardiovascular disturbances.

Synonyms(1)

Synonym
Ciguatera Poisoning

Research Excerpts

Overview

ExcerptReference
"Risk factors for ciguatera poisoning are ingestion of larger portions of reef fish from ciguatera-prone areas."( Lewis, RJ; Lucas, RE; Taylor, JM, 1997)
"Ciguatera poisoning is a food-borne neuro-intoxication caused by consumption of finfish that have accumulated ciguatoxins in their tissues."( Craig, SB; Eaglesham, GK; Graham, GC; Lewis, RJ; Poole, S; Stewart, I, 2010)
"Ciguatera poisoning is one of the most prevalent types of fish poisoning, but it is often underreported, leading many health practitioners to be unfamiliar in correctly identifying and treating this toxicity."( Jutzy, K; Patel, M, 2020)
"Ciguatera poisoning is a global health concern caused by the consumption of seafood containing ciguatoxins (CTXs)."( Kryuchkov, F; Miles, CO; Mudge, EM; Robertson, A; Uhlig, S; Van Gothem, S, 2022)
"Ciguatera Poisoning is an emerging risk in the east Atlantic Ocean."( Burlingame, A; Estevez, P; Gago Martinez, A; Oses Prieto, J, 2023)

Context

ExcerptReference
"Ciguatera poisoning has long been recognized as a serious problem in the tropical and subtropical regions of the world."( Juranovic, LR; Park, DL, 1991)
"Ciguatera poisoning has to be considered in the diagnosis of acute gastroenteritis affecting travellers to tropical areas."( Corachán, M; Gascón, J; Macià, M; Oliveira, I, 2003)
"Ciguatera poisoning has caused illnesses in New Zealand through the consumption of contaminated reef fish imported from Pacific Islands."( Harwood, DT; Murray, JS; Rhodes, LL, 2021)

Treatment

ExcerptReference
"Mannitol treatment for Ciguatera Poisoning, 35 patients were treated from the Miami-Caribbean area with symptoms of acute and chronic Ciguatera Poisoning."( Ayyar, RA; Baden, DG; Blythe, DG; De Sylva, DP; Fleming, LE; Shrank, K, 1992)

Research

Studies (280)

TimeframeStudies, This Condition (%)All Conditions %
pre-199024 (8.57)23.3326
1990's48 (17.14)12.5806
2000's65 (23.21)18.1394
2010's81 (28.93)28.8240
2020's62 (22.14)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low20
histamine0low40
nitrates0low10
nitrous oxide0low10
urea0low10
amitriptyline0low40
carbamazepine0low10
chloroxylenol0low10
diphenhydramine0low10
fluoxetine0low10
gabapentin0low10
lidocaine0low30
methamidophos0low10
neostigmine0low10
nifedipine0low10
piracetam0low10
histidine0low10
kainic acid0low30
chlorine0low20
phenyl acetate0low10
substance p0low10
tocainide0low10
tetramethylenedisulfotetramine0low10
homoanatoxin0low10
atropine0low20
ouabain0low20
linezolid0low10
glycosides0low10
thiopental0low10
thiobutabarbital0low10
rosmarinic acid0low10
domoic acid0low30
levetiracetam0low10
ciguatoxins0medium2031
phosphorus0low10
pregabalin0low10
tetrodotoxin0low150
gambierol0low50
ciguatoxin 3c0low30
palytoxin0low30
veratridine0low20
podophyllin0low10
clove0low30
ants0low10
yessotoxin0low10
chlorophyll a0low10
dinophysistoxin 10low10
azaspiracid0low10
calca protein, human0low10
brevetoxin0medium61
saxitoxin0low40
okadaic acid0low20
maitotoxin0low50
ciguatoxin 20low20
bassianolide0low80
vitamin b 120low10
exudates0low20
pralidoxime0low10
eye0low10
gambierone0low40

Protein Targets (646)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
thioredoxin reductase100010
USP1 protein, partial9009
NFKB1 protein, partial2002
GLS protein8008
cytochrome P450 family 3 subfamily A polypeptide 45005
cytochrome P450 2D64004
arylsulfatase A4004
cytochrome P450 2D6 isoform 13003
D(1A) dopamine receptor4004
chromobox protein homolog 19009
atrial natriuretic peptide receptor 2 precursor3003
serine/threonine-protein kinase mTOR isoform 13003
nuclear factor erythroid 2-related factor 2 isoform 18008
muscarinic acetylcholine receptor M16006
Solute carrier family 22 member 1 0203
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
ATP-binding cassette sub-family C member 3011011
Multidrug resistance-associated protein 4011011
Voltage-dependent L-type calcium channel subunit alpha-1F0404
5-hydroxytryptamine receptor 4010010
Bile salt export pump017017
Albumin0033
High affinity nerve growth factor receptor0123
Aldo-keto reductase family 1 member B10606
Muscarinic acetylcholine receptor M206111
Muscarinic acetylcholine receptor M406110
Muscarinic acetylcholine receptor M10417
Muscarinic acetylcholine receptor M30316
Muscarinic acetylcholine receptor M40316
5-hydroxytryptamine receptor 2C0303
Muscarinic acetylcholine receptor M50316
Muscarinic acetylcholine receptor M508112
Alpha-2A adrenergic receptor0303
Muscarinic acetylcholine receptor M20317
Muscarinic acetylcholine receptor M108113
Angiotensin-converting enzyme0606
D(2) dopamine receptor0202
5-hydroxytryptamine receptor 2A0505
Alpha-2B adrenergic receptor0415
Alpha-2C adrenergic receptor0202
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M308112
D(1A) dopamine receptor0202
D(1B) dopamine receptor0101
UDP-glucuronosyltransferase 1A40001
Sodium-dependent noradrenaline transporter 0819
Histamine H2 receptor0325
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2A0606
5-hydroxytryptamine receptor 2C010010
5-hydroxytryptamine receptor 1B0202
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0303
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0314
Sodium-dependent serotonin transporter0426
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Histamine H1 receptor0628
D(3) dopamine receptor0202
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 4 subunit alpha0506
UDP-glucuronosyltransferase 1A30001
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 2B0606
Alpha-1A adrenergic receptor0505
Histamine H2 receptor2117
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60404
5-hydroxytryptamine receptor 70202
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Sodium-dependent dopamine transporter 0415
Potassium voltage-gated channel subfamily H member 2010010
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0405
Sodium channel protein type 5 subunit alpha0505
Sodium channel protein type 9 subunit alpha0707
Sigma non-opioid intracellular receptor 10112
5-hydroxytryptamine receptor 4 0101
Nuclear receptor subfamily 3 group C member 3 0606
Canalicular multispecific organic anion transporter 1011011
Sodium channel protein type 2 subunit alpha0303
Ataxin-25005
Sigma non-opioid intracellular receptor 10404
5-hydroxytryptamine receptor 3B0101
Sodium channel protein type 3 subunit alpha0404
Sodium channel protein type 11 subunit alpha0303
Sodium channel protein type 8 subunit alpha0303
Histamine H3 receptor0325
Sodium channel protein type 10 subunit alpha0303
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase4004
RAR-related orphan receptor gamma9009
GLI family zinc finger 37007
AR protein140014
thioredoxin glutathione reductase3003
glucocorticoid receptor [Homo sapiens]9009
retinoic acid nuclear receptor alpha variant 16006
estrogen-related nuclear receptor alpha8008
estrogen nuclear receptor alpha120012
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
IDH16006
euchromatic histone-lysine N-methyltransferase 2160016
nuclear factor erythroid 2-related factor 2 isoform 23003
thyroid hormone receptor beta isoform 26006
lethal(3)malignant brain tumor-like protein 1 isoform I2002
geminin130013
lethal factor (plasmid)2002
lamin isoform A-delta10160016
Polyphenol oxidase 20202
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Spike glycoprotein4004
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, 2-oxoglutarate Oxygenase4004
nuclear receptor subfamily 1, group I, member 35005
retinoid X nuclear receptor alpha7007
pregnane X nuclear receptor6006
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M40101
Reverse transcriptase/RNaseH 0102
Muscarinic acetylcholine receptor0112
Chain A, Beta-lactamase8008
TDP1 protein8008
thyroid stimulating hormone receptor7007
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
thyroid hormone receptor beta isoform a3003
mitogen-activated protein kinase 13003
Vpr1001
Bile salt export pump0303
Major prion protein0011
Cellular tumor antigen p539009
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
Cytochrome P450 2C9 0506
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 2B60011
Cytochrome P450 2J20404
Frizzled-80011
P2X purinoceptor 40101
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, Ferritin light chain4004
15-lipoxygenase, partial1001
G4004
v-jun sarcoma virus 17 oncogene homolog (avian)6006
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
heat shock protein beta-12002
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)4004
DNA polymerase kappa isoform 13003
cytochrome P450 3A4 isoform 14004
Gamma-aminobutyric acid receptor subunit pi4307
Voltage-dependent calcium channel gamma-2 subunit4004
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Gamma-aminobutyric acid receptor subunit beta-14307
Gamma-aminobutyric acid receptor subunit delta4307
Gamma-aminobutyric acid receptor subunit gamma-24318
Glutamate receptor 25218
Gamma-aminobutyric acid receptor subunit alpha-54307
Gamma-aminobutyric acid receptor subunit alpha-34307
Amine oxidase [flavin-containing] A0303
Gamma-aminobutyric acid receptor subunit gamma-14307
Gamma-aminobutyric acid receptor subunit alpha-24307
Gamma-aminobutyric acid receptor subunit alpha-44307
Gamma-aminobutyric acid receptor subunit gamma-34307
Gamma-aminobutyric acid receptor subunit alpha-64307
Gamma-aminobutyric acid receptor subunit alpha-14318
Gamma-aminobutyric acid receptor subunit beta-34307
Gamma-aminobutyric acid receptor subunit beta-24318
GABA theta subunit4307
Inositol hexakisphosphate kinase 14004
Gamma-aminobutyric acid receptor subunit epsilon4307
cytochrome P450 2C9, partial4004
Luciferase2002
phosphopantetheinyl transferase5005
Thrombopoietin2002
regulator of G-protein signaling 47007
EWS/FLI fusion protein6006
vitamin D3 receptor isoform VDRA3003
potassium voltage-gated channel subfamily H member 2 isoform d5005
huntingtin isoform 22002
Histamine H1 receptor0124
Histamine N-methyltransferase0001
Solute carrier family 22 member 10203
Calcium release-activated calcium channel protein 10101
Protein orai-20101
Protein orai-30101
Histamine H4 receptor0224
Histamine H3 receptor0102
Solute carrier family 22 member 20203
Chain A, JmjC domain-containing histone demethylation protein 3A3003
ATAD5 protein, partial7007
apical membrane antigen 1, AMA12002
importin subunit beta-1 isoform 12002
snurportin-12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
survival motor neuron protein isoform d4004
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)3003
progesterone receptor3003
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma5005
caspase-32002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
Histone H2A.x2002
Caspase-71001
NPC intracellular cholesterol transporter 1 precursor2002
caspase-31001
ras-related protein Rab-9A2002
peripheral myelin protein 223003
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Sodium-dependent noradrenaline transporter0101
Potassium channel subfamily K member 20213
ATP-dependent translocase ABCB10202
Cytochrome P450 3A40304
Cytochrome P450 2C80101
Cytochrome P450 2D60203
Dipeptidyl peptidase 40101
Gamma-aminobutyric acid receptor subunit alpha-10213
Alpha-1B adrenergic receptor0404
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20213
Alpha-2B adrenergic receptor0101
Acetylcholinesterase0101
Alpha-2C adrenergic receptor0101
Acetylcholinesterase0404
Alpha-2A adrenergic receptor0101
Prostaglandin G/H synthase 10202
Alpha-1D adrenergic receptor0202
Sodium-dependent dopamine transporter0202
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50213
Sodium-dependent serotonin transporter0202
Cytochrome P450 2C190203
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40213
D(2) dopamine receptor0112
Gamma-aminobutyric acid receptor subunit epsilon0202
Gastrin/cholecystokinin type B receptor 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Gamma-aminobutyric acid receptor subunit alpha-60213
Cytochrome P450 1B10101
Sigma intracellular receptor 20101
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0101
Beta-2 adrenergic receptor0102
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Sigma non-opioid intracellular receptor 10101
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0101
aldehyde dehydrogenase 1 family, member A16006
Bloom syndrome protein isoform 16006
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
Voltage-dependent calcium channel subunit alpha-2/delta-10101
ATP-dependent phosphofructokinase6006
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0023
bromodomain adjacent to zinc finger domain 2B4004
transcriptional regulator ERG isoform 31001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
histone acetyltransferase KAT2A isoform 15005
neuropeptide S receptor isoform A1001
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10202
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 432002
Histone deacetylase 10101
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
GALC protein1001
transforming acidic coiled-coil-containing protein 30001
Solute carrier family 22 member 20001
Carbonic anhydrase 120002
Solute carrier family 22 member 30102
Carbonic anhydrase 10104
Carbonic anhydrase 20105
Plasma kallikrein0002
Carbonic anhydrase 30002
Macrophage migration inhibitory factor0202
Carbonic anhydrase 40103
Carbonic anhydrase 60002
Adenosine receptor A10002
5-hydroxytryptamine receptor 1D0002
Adenosine receptor A2a0103
Metabotropic glutamate receptor 50112
Carbonic anhydrase 5A, mitochondrial0002
Glutamate receptor ionotropic, NMDA 1 0215
Carbonic anhydrase0103
Carbonic anhydrase 70002
Carbonic anhydrase0003
Histamine H3 receptor0101
Glutamate receptor ionotropic, NMDA 2A 0215
Glutamate receptor ionotropic, NMDA 2B0215
Glutamate receptor ionotropic, NMDA 2C0215
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0202
Carbonic anhydrase 90002
Carbonic anhydrase 0003
Carbonic anhydrase-like protein, putative0002
Carbonic anhydrase0003
Carbonic anhydrase0003
Glutamate receptor ionotropic, NMDA 2D0215
Carbonic anhydrase 0003
Equilibrative nucleoside transporter 40001
Carbonic anhydrase 130002
Glutamate receptor ionotropic, NMDA 3B0215
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Carbonic anhydrase 40002
Carbonic anhydrase 150103
Carbonic anhydrase 130002
Carboxylic ester hydrolase 0001
Glutamate receptor ionotropic, NMDA 3A0215
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
Chain A, HISTIDINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
flap endonuclease 13003
Histidine-binding periplasmic protein0011
Large neutral amino acids transporter small subunit 10101
Chain A, Glutamate receptor 20011
Chain A, Glutamate receptor 20011
Chain C, Glutamate receptor 20011
endonuclease IV2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
nuclear receptor ROR-gamma isoform 12002
Metabotropic glutamate receptor 60011
Glutamate receptor 11214
Glutamate receptor 31214
Glutamate receptor 41214
Glutamate receptor ionotropic, kainate 10213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 50011
Glutamate receptor ionotropic, kainate 20224
Glutamate receptor 10112
Glutamate receptor 20112
Glutamate receptor 30011
Glutamate receptor ionotropic, kainate 30202
Glutamate receptor 40101
Glutamate receptor ionotropic, kainate 40202
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor ionotropic, kainate 30202
Glutamate receptor ionotropic, kainate 40101
Glutamate receptor ionotropic, kainate 50202
Glutamate receptor ionotropic, kainate 50202
chaperonin-containing TCP-1 beta subunit homolog1001
Synaptic vesicle glycoprotein 2A0202
Microtubule-associated protein tau3003
Potassium channel subfamily K member 30101
Potassium voltage-gated channel subfamily A member 50202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Multidrug and toxin extrusion protein 10101
streptokinase A precursor0011
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Cytochrome P450 1A20203
Estrogen receptor0011
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] B0101
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial0101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Estrogen receptor beta0011
Renin0101
activating transcription factor 63003
farnesoid X nuclear receptor4004
Acetylcholinesterase0101
Cholinesterase0303
Cholinesterase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
pregnane X receptor1001
hypoxia-inducible factor 1 alpha subunit1001
Fumarate hydratase1001
Smad31001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
hypothetical protein, conserved1001
nonstructural protein 12002
polyprotein1001
67.9K protein1001
Parkin1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
aryl hydrocarbon receptor1001
thyroid stimulating hormone receptor2002
beta-2 adrenergic receptor1001
peripheral myelin protein 22 isoform 12002
cellular tumor antigen p53 isoform a1001
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
perilipin-50101
perilipin-10101
serine/threonine-protein kinase PLK11001
eyes absent homolog 2 isoform a1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 11001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Glutathione reductase, mitochondrial0202
Integrin beta-31001
Integrin alpha-IIb1001
Adenosine receptor A30202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Phospholipase A2, membrane associated0001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Thromboxane-A synthase 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A2a0101
Adenosine receptor A10202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
C-C chemokine receptor type 20202
Nuclear receptor ROR-gamma1001
Inositol monophosphatase 11001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Leukotriene B4 receptor 10001
Myosin light chain kinase, smooth muscle0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
ATPase family AAA domain-containing protein 52002
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Leukotriene B4 receptor 20001
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Sodium/iodide cotransporter0101
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)0101
Chain L, Igg2b-kappa 40-50 Fab (light Chain)0101
Chain A, Na, K-ATPase alpha subunit0011
SMAD family member 21001
PPM1D protein1001
SMAD family member 31001
STAT3, partial0101
Kruppel-like factor 50101
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Sodium/potassium-transporting ATPase subunit alpha-1 0203
Sodium/potassium-transporting ATPase subunit beta-10203
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
Sodium/potassium-transporting ATPase subunit beta-1 0101
Replicase polyprotein 1ab0202
Sodium/potassium-transporting ATPase subunit alpha-30102
Sodium/potassium-transporting ATPase subunit beta-20102
Solute carrier organic anion transporter family member 1A10001
Solute carrier organic anion transporter family member 1A20001
Sodium/potassium-transporting ATPase subunit alpha-20203
Sodium/potassium-transporting ATPase subunit beta-30102
Sodium/potassium-transporting ATPase subunit gamma0102
Sodium/potassium-transporting ATPase subunit alpha-40102
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10001
Guanine nucleotide-binding protein G1001
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Pyridoxal kinase0001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Mcl-10101
glucocerebrosidase1001
Replicase polyprotein 1ab0101
lysosomal alpha-glucosidase preproprotein1001
pyruvate kinase PKM isoform a1001
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase0101
Lysine-specific histone demethylase 1A0101
Transthyretin0011
Interstitial collagenase0101
Amyloid-beta precursor protein0112
Transcription factor AP-10101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0202
Proto-oncogene tyrosine-protein kinase Src0101
Aldo-keto reductase family 1 member B10101
17-beta-hydroxysteroid dehydrogenase type 20101
Alpha-synuclein0101
Linoleate 9S-lipoxygenase-40101
UDP-galactopyranose mutase0011
Hyaluronidase-10101
UDP-galactopyranose mutase0011
Integrase 0101
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-K receptor0202
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-P receptor0101
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Mas-related G-protein coupled receptor member X20011
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Fatty-acid amide hydrolase 10101
Rap guanine nucleotide exchange factor 31001
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]