Compounds > equisetin
Page last updated: 2024-08-03 18:51:42

equisetin

Description

equisetin: antibiotic from Fusarium equiseti; derivative of N-methyl-2,4-pyrollidone with elemental composition C22-H31-N-O4; N1 same as NM [MeSH]

equisetin : A member of the class of tetramic acids that is trichosetin in which the hydrogen attached to the lactam nitrogen has been replaced by a methyl group. It is produced by the filamentous fungus Fusarium heterosporum. [CHeBI]

Cross-References

ID SourceID
PubMed CID54679016
CHEBI ID142135
MeSH IDM0082792

Synonyms (7)

Synonym
NSC159160 ,
equisetin
57749-43-6
LS-64262 ,
CHEBI:142135
n-methyltrichosetin
(3z,5s)-3-[{(1s,2r,4as,6r,8ar)-1,6-dimethyl-2-[(1e)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl}(hydroxy)methylidene]-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione

Roles (4)

RoleDescription
antibacterial agentA substance (or active part thereof) that kills or slows the growth of bacteria.
quorum sensing inhibitorAny compound that interferes with bacterial communication (quorum sensing, QS).
HIV-1 integrase inhibitorAn inhibitor of HIV-1 integrase, an enzyme required for the integration of the genetic material of the retrovirus into the DNA of the infected cells.
fungal metaboliteAny eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.

Drug Classes (4)

ClassDescription
enolAlkenols; the term refers specifically to vinylic alcohols, which have the structure HOCR'=CR2. Enols are tautomeric with aldehydes (R' = H) or ketones (R' =/= H).
octahydronaphthalenesAny carbobycyclic compound that is an octahydronaphthalene or a compound obtained from an octahydronaphthalene by formal substitution of one or more hydrogens.
primary alcoholA primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
tetramic acidsCompounds containing a tetramic acid (pyrrolidine-2,4-dione) ring system.

Research

Studies (32)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (3.13)18.7374
1990's3 (9.38)18.2507
2000's7 (21.88)29.6817
2010's18 (56.25)24.3611
2020's3 (9.38)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.03%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other32 (96.97%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
beta-thujaplicin
0
cyclic ketone;
enol;
monoterpenoid		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiplasmodial drug;
plant metabolite		00low000000
kojic acid
0
4-pyranones;
enol;
primary alcohol		Aspergillus metabolite;
EC 1.10.3.1 (catechol oxidase) inhibitor;
EC 1.10.3.2 (laccase) inhibitor;
EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 1.4.3.3 (D-amino-acid oxidase) inhibitor;
NF-kappaB inhibitor;
skin lightening agent		00low000000
tropolone
0
alpha-hydroxy ketone;
cyclic ketone;
enol		bacterial metabolite;
fungicide;
toxin		00low000000
formestane
0
17-oxo steroid;
3-oxo-Delta(4) steroid;
enol;
hydroxy steroid		antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor		00low000000
furaneol
0
cyclic ketone;
enol;
furans		flavouring agent;
fragrance;
plant metabolite		00low000000
4-hydroxy-2-ethyl-5-methyl-3(2h)-furanone
0
cyclic ketone;
enol;
furans		Saccharomyces cerevisiae metabolite00low000000
3,7-dihydroxytropolone
0
alpha-hydroxy ketone;
cyclic ketone;
enol;
triol		antineoplastic agent;
bacterial metabolite		00low000000
4-hydroxy-5-methyl-3(2h)-furanone
0
cyclic ketone;
enol;
furans		metabolite00low000000
australifungin
0
carbobicyclic compound;
enol;
enone;
secondary alcohol		antifungal agent;
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor;
HIV-1 integrase inhibitor;
metabolite		00low000000
isopentenol
0
enol00low000000
sq-23377
0
cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid		calcium ionophore;
metabolite		00low000000
pyranonigrin a
0
cyclic ketone;
enol;
gamma-lactam;
pyranopyrrole;
secondary alcohol		antioxidant;
Aspergillus metabolite;
marine metabolite		00low000000
lfm a13
0
aromatic amide;
dibromobenzene;
enamide;
enol;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 2.7.11.21 (polo kinase) inhibitor;
geroprotector;
platelet aggregation inhibitor		00low000000
teriflunomide
0
(trifluoromethyl)benzenes;
aromatic amide;
enamide;
enol;
nitrile;
secondary carboxamide		drug metabolite;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
tyrosine kinase inhibitor		00low000000
streptolydigin
0
bridged compound;
cyclic ketal;
enol;
monocarboxylic acid amide;
N-glycosyl compound;
organic heterobicyclic compound;
pyrrolidinone;
spiro-epoxide		antimicrobial agent;
bacterial metabolite;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
lancifodilactone g
0
cyclic ether;
diol;
enol;
gamma-lactone;
oxaspiro compound;
triterpenoid		anti-HIV agent;
metabolite		00low000000
alpha-eudesmol
0
eudesmane sesquiterpenoid;
octahydronaphthalenes;
tertiary alcohol		volatile oil component00low000000
solanapyrone a
0
octahydronaphthalenes;
pyrancarbaldehyde;
solanapyrone		EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor00low000000
terpentecin
0
carbocyclic antibiotic;
diterpenoid;
octahydronaphthalenes;
secondary alpha-hydroxy ketone		00low000000
t-cadinol
0
cadinane sesquiterpenoid;
carbobicyclic compound;
octahydronaphthalenes;
tertiary alcohol		plant metabolite;
volatile oil component		00low000000
capsidiol
0
eremophilane sesquiterpenoid;
octahydronaphthalenes;
sesquiterpene phytoalexin		antifungal agent;
plant metabolite		00low000000
drimenol
0
homoallylic alcohol;
octahydronaphthalenes;
primary alcohol;
sesquiterpenoid		00low000000
t-muurolol
0
cadinane sesquiterpenoid;
carbobicyclic compound;
octahydronaphthalenes;
tertiary alcohol		bacterial metabolite;
fungicide;
marine metabolite;
plant metabolite;
volatile oil component		00low000000
gamma-cadinene
0
cadinene;
gamma-cadinene;
octahydronaphthalenes		00low000000
alpha-cadinol
0
cadinane sesquiterpenoid;
carbobicyclic compound;
octahydronaphthalenes;
tertiary alcohol		fungicide;
plant metabolite;
volatile oil component		00low000000
artemisic acid
0
carbobicyclic compound;
monocarboxylic acid;
octahydronaphthalenes;
sesquiterpenoid		metabolite00low000000
dihydroartemisinic acid
0
carbobicyclic compound;
monocarboxylic acid;
octahydronaphthalenes;
sesquiterpenoid		plant metabolite00low000000
amorpha-4,11-diene
0
octahydronaphthalenes;
sesquiterpene		00low000000
solanapyrone b
0
octahydronaphthalenes;
solanapyrone		00low000000
dihydromonacolin l
0
2-pyranones;
octahydronaphthalenes		00low000000
oplodiol
0
carbobicyclic compound;
octahydronaphthalenes;
secondary alcohol;
sesquiterpenoid;
tertiary alcohol		plant metabolite00low000000
ilicicolin h
0
aromatic ketone;
carbobicyclic compound;
ilicicolin;
monohydroxypyridine;
octahydronaphthalenes;
phenols;
pyridone		antimicrobial agent;
mitochondrial respiratory-chain inhibitor		00low000000
1-butanol
0
alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol		human metabolite;
mouse metabolite;
protic solvent		00low000000
ethanolamine
0
ethanolamines;
primary alcohol;
primary amine		Escherichia coli metabolite;
human metabolite;
mouse metabolite		00low000000
glycolic acid
0
2-hydroxy monocarboxylic acid;
primary alcohol		keratolytic drug;
metabolite		00low000000
methanol
0
alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite		00low000000
1-octanol
0
octanol;
primary alcohol		antifungal agent;
bacterial metabolite;
fuel additive;
kairomone;
plant metabolite		00low000000
thiamine
0
primary alcohol;
vitamin B1		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		00low000000
2-(4-methyl-1,3-thiazol-5-yl)ethanol
0
1,3-thiazoles;
primary alcohol		Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite		00low000000
mercaptoethanol
0
alkanethiol;
primary alcohol		geroprotector00low000000
4-imidazolemethanol
0
imidazoles;
primary alcohol		00low000000
aa 861
0
1,4-benzoquinones;
acetylenic compound;
primary alcohol		EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor		00low000000
benserazide
0
carbohydrazide;
catechols;
primary alcohol;
primary amino compound		antiparkinson drug;
dopaminergic agent;
EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor		00low000000
dimercaprol
0
dithiol;
primary alcohol		chelator00low000000
hydroxychloroquine
0
aminoquinoline;
organochlorine compound;
primary alcohol;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
dermatologic drug		00low000000
idebenone
0
1,4-benzoquinones;
primary alcohol		antioxidant;
ferroptosis inhibitor		00low000000
metronidazole
0
C-nitro compound;
imidazoles;
primary alcohol		antiamoebic agent;
antibacterial drug;
antimicrobial agent;
antiparasitic agent;
antitrichomonal drug;
environmental contaminant;
prodrug;
radiosensitizing agent;
xenobiotic		00low000000
2-aminopropanol
0
amino alcohol;
primary alcohol;
primary amino compound		00low000000
salmeterol xinafoate
0
ether;
phenols;
primary alcohol;
secondary alcohol;
secondary amino compound		00low000000
phenylethyl alcohol
0
benzenes;
primary alcohol		Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite		00low000000
trimethylolpropane
0
primary alcohol00low000000
isobutyl alcohol
0
alkyl alcohol;
primary alcohol		Saccharomyces cerevisiae metabolite00low000000
glycol salicylate
0
phenols;
primary alcohol;
salicylates		00low000000
veratryl alcohol
0
benzyl alcohols;
dimethoxybenzene;
primary alcohol		fungal metabolite00low000000
tetrahydrofurfuryl alcohol
0
oxolanes;
primary alcohol		protic solvent00low000000
furfuryl alcohol
0
furans;
primary alcohol		Maillard reaction product00low000000
2-diethylaminoethanol
0
ethanolamines;
primary alcohol;
tertiary amino compound		00low000000
2-ethylhexanol
0
primary alcoholplant metabolite;
volatile oil component		00low000000
2-ethoxyethanol
0
glycol ether;
primary alcohol		protic solvent;
teratogenic agent		00low000000
1-hexanol
0
hexanol;
primary alcohol		alarm pheromone;
antibacterial agent;
fragrance;
plant metabolite		00low000000
1,5-pentanediol
0
primary alcohol00low000000
heptanol
0
heptanol;
primary alcohol		flavouring agent;
fragrance;
gap junctional intercellular communication inhibitor;
plant metabolite		00low000000
n-butoxyethanol
0
glycol ether;
primary alcohol		protic solvent00low000000
carbitol
0
diether;
glycol ether;
hydroxypolyether;
primary alcohol		protic solvent00low000000
triethylene glycol
0
diol;
poly(ethylene glycol);
primary alcohol		plasticiser00low000000
n-decyl alcohol
0
decanol;
primary alcohol		metabolite;
pheromone;
protic solvent		00low000000
undecan-1-ol
0
primary alcohol;
undecanol		flavouring agent;
plant metabolite		00low000000
dodecanol
0
dodecanol;
primary alcohol		bacterial metabolite;
cosmetic;
insect attractant;
insecticide;
pheromone;
plant metabolite		00low000000
pentaerythritol
0
primary alcohol;
tetrol		flame retardant;
laxative		00low000000
acetol
0
methyl ketone;
primary alcohol;
primary alpha-hydroxy ketone;
propanones		Escherichia coli metabolite;
human metabolite;
mouse metabolite		00low000000
2-methylbutanol
0
alkyl alcohol;
primary alcohol		Saccharomyces cerevisiae metabolite00low000000
1-nonanol
0
nonanol;
primary alcohol		antifungal agent;
flavouring agent;
plant metabolite;
volatile oil component		00low000000
3-amino-1-propanol
0
primary alcohol;
primary amine;
propanolamine		00low000000
3-hexen-1-ol
0
alkenyl alcohol;
homoallylic alcohol;
primary alcohol;
volatile organic compound		plant metabolite00low000000
glycidol
0
epoxide;
primary alcohol		00low000000
3-methylbenzyl alcohol
0
methylbenzyl alcohol;
primary alcohol		00low000000
3-Bromo-1-propanol
0
primary alcohol00low000000
hexamethylene glycol
0
diol;
primary alcohol		00low000000
clopenthixol
0
N-alkylpiperazine;
primary alcohol;
thioxanthenes		alpha-adrenergic antagonist;
dopaminergic antagonist;
first generation antipsychotic;
H1-receptor antagonist;
serotonergic antagonist		00low000000
dihydroconiferyl alcohol
0
eugenol;
primary alcohol		plant metabolite00low000000
pentaethylene glycol monododecyl ether
0
hydroxypolyether;
pentaethylene glycol;
primary alcohol		nonionic surfactant00low000000
2,2-bis(bromomethyl)-1,3-propanediol
0
primary alcohol00low000000
butylhydroxybutylnitrosamine
0
nitrosamine;
primary alcohol		carcinogenic agent00low000000
aethoxysclerol
0
hydroxyether;
primary alcohol		00low000000
n-ethyl-n-hydroxyethylnitrosamine
0
nitrosamine;
primary alcohol		carcinogenic agent00low000000
phenoxyethanol
0
aromatic ether;
glycol ether;
primary alcohol		antiinfective agent;
central nervous system depressant		00low000000
isopentyl alcohol
0
alkyl alcohol;
primary alcohol;
volatile organic compound		antifungal agent;
Saccharomyces cerevisiae metabolite;
xenobiotic metabolite		00low000000
toloxatone
0
oxazolidinone;
primary alcohol;
toluenes		00low000000
deoxynivalenol
0
cyclic ketone;
enone;
primary alcohol;
secondary alpha-hydroxy ketone;
trichothecene;
triol		mycotoxin00low000000
5-benzylacyclouridine
0
hydroxyether;
primary alcohol;
pyrimidone		00low000000
loxtidine
0
aromatic ether;
piperidines;
primary alcohol;
triazoles		H2-receptor antagonist00low000000
lamivudine
0
monothioacetal;
nucleoside analogue;
oxacycle;
primary alcohol		allergen;
anti-HBV agent;
antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor;
HIV-1 reverse transcriptase inhibitor;
prodrug		00low000000
1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine
0
aryl sulfide;
primary alcohol;
pyrimidone		antiviral drug;
HIV-1 reverse transcriptase inhibitor		00low000000
oxetanocin a
0
diol;
nucleoside analogue;
oxetanes;
primary alcohol		anti-HIV agent;
antibacterial agent;
bacterial metabolite		00low000000
5-hydroxymethyluracil
0
primary alcohol;
pyrimidone		human metabolite00low000000
methylthioethanol
0
aliphatic sulfide;
primary alcohol		plant metabolite;
xenobiotic metabolite		00low000000
glyceryl 1,2-dinitrate
0
dinitroglycerol;
primary alcohol		00low000000
3,4-dihydroxyphenylethanol
0
catechols;
primary alcohol		antineoplastic agent;
antioxidant;
metabolite		00low000000
erythrodiol
0
diol;
pentacyclic triterpenoid;
primary alcohol;
secondary alcohol		plant metabolite00low000000
bosentan anhydrous
0
primary alcohol;
pyrimidines;
sulfonamide		antihypertensive agent;
endothelin receptor antagonist		00low000000
cafestol
0
diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
hypoglycemic agent;
plant metabolite		00low000000
chrysanthemol
0
cyclopropanes;
homoallylic alcohol;
monoterpenoid;
primary alcohol		00low000000
kahweol
0
diterpenoid;
furans;
organic heteropentacyclic compound;
primary alcohol;
tertiary alcohol		angiogenesis inhibitor;
anti-inflammatory agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
plant metabolite		00low000000
4-methylcyclohexanemethanol
0
aliphatic alcohol;
carbocyclic compound;
primary alcohol		00low000000
nsc 224070
0
1,4-benzoquinones;
aziridines;
enamine;
primary alcohol;
secondary amino compound		alkylating agent;
antineoplastic agent		00low000000
chrysobactin
0
catechols;
dipeptide;
monocarboxylic acid;
primary alcohol;
primary amino compound		bacterial metabolite;
siderophore		00low000000
5-benzyloxybenzylacyclouridine
0
benzyl ether;
hydroxyether;
primary alcohol		00low000000
isolariciresinol
0
guaiacols;
lignan;
polyphenol;
primary alcohol		plant metabolite00low000000
albicanol
0
carbobicyclic compound;
homoallylic alcohol;
primary alcohol;
sesquiterpenoid		antifeedant;
antifungal agent;
antineoplastic agent;
fungal metabolite;
mammalian metabolite;
marine metabolite;
plant metabolite		00low000000
enrasentan
0
aromatic ether;
benzodioxoles;
indanes;
monocarboxylic acid;
monomethoxybenzene;
primary alcohol		antihypertensive agent;
endothelin receptor antagonist		00low000000
5-hydroxymethylfurfural
0
arenecarbaldehyde;
furans;
primary alcohol		indicator;
Maillard reaction product		00low000000
withaferin a
0
27-hydroxy steroid;
4-hydroxy steroid;
delta-lactone;
enone;
epoxy steroid;
ergostanoid;
primary alcohol;
secondary alcohol;
withanolide		antineoplastic agent;
apoptosis inducer		00low000000
lariciresinol
0
aromatic ether;
lignan;
oxolanes;
phenols;
primary alcohol		antifungal agent;
plant metabolite		00low000000
veratrone
0
aromatic ketone;
dimethoxybenzene;
primary alcohol		00low000000
(2S,3R)-dihydrodehydrodiconiferyl alcohol
0
1-benzofurans;
guaiacols;
guaiacyl lignin;
primary alcohol		00low000000
lactucin
0
azulenofuran;
cyclic terpene ketone;
enone;
primary alcohol;
secondary alcohol;
sesquiterpene lactone		antimalarial;
plant metabolite;
sedative		00low000000
cleomiscosin a
0
aromatic ether;
delta-lactone;
organic heterotricyclic compound;
phenols;
primary alcohol		anti-inflammatory agent;
metabolite		00low000000
ergonovine
0
ergot alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound;
primary alcohol;
secondary amino compound;
tertiary amino compound		diagnostic agent;
fungal metabolite;
oxytocic;
toxin		00low000000
1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one
0
benzoic acids;
primary alcohol;
pyrrolidin-2-ones;
secondary amino compound		00low000000
(north)-methanocarbathymidine
0
C-glycosyl pyrimidine;
carbobicyclic compound;
primary alcohol;
pyrimidone;
secondary alcohol		00low000000
phenylalaninol
0
amino alcohol;
amphetamines;
primary alcohol;
primary amino compound		00low000000
16beta,17-dihydroxy-ent-kaurane-19-oic acid
0
bridged compound;
diol;
ent-kaurane diterpenoid;
hydroxy monocarboxylic acid;
primary alcohol;
tertiary alcohol		anti-HIV agent;
metabolite		00low000000
egonol
0
1-benzofurans;
aromatic ether;
benzodioxoles;
primary alcohol		plant metabolite00low000000
sordaricin
0
3-oxo monocarboxylic acid;
aldehyde;
bridged compound;
primary alcohol;
tetracyclic diterpenoid		antifungal agent;
fungal metabolite		00low000000
3-mercaptohexanol
0
alkanethiol;
primary alcohol		flavouring agent;
plant metabolite;
Saccharomyces cerevisiae metabolite		00low000000
geraniol
0
3,7-dimethylocta-2,6-dien-1-ol;
monoterpenoid;
primary alcohol		allergen;
fragrance;
plant metabolite;
volatile oil component		00low000000
crotonyl alcohol
0
primary alcohol00low000000
ospemifene
0
aromatic ether;
organochlorine compound;
primary alcohol		anti-inflammatory agent;
antineoplastic agent;
estrogen receptor modulator		00low000000
chanoclavine
0
benzoindole;
ergot alkaloid;
organic heterotricyclic compound;
primary alcohol;
secondary amino compound		00low000000
plaunotol
0
diterpenoid;
primary alcohol		anti-ulcer drug;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
nephroprotective agent;
plant metabolite;
vulnerary		00low000000
kn 93
0
monochlorobenzenes;
monomethoxybenzene;
primary alcohol;
sulfonamide;
tertiary amino compound		EC 2.7.11.17 (Ca(2+)/calmodulin-dependent protein kinase) inhibitor;
geroprotector		00low000000
syringin
0
beta-D-glucoside;
dimethoxybenzene;
monosaccharide derivative;
primary alcohol		hepatoprotective agent;
plant metabolite		00low000000
andrographolide
0
carbobicyclic compound;
gamma-lactone;
labdane diterpenoid;
primary alcohol;
secondary alcohol		anti-HIV agent;
anti-inflammatory drug;
antineoplastic agent;
metabolite		00low000000
dehydrodiconiferyl alcohol
0
1-benzofurans;
guaiacols;
guaiacyl lignin;
primary alcohol		anti-inflammatory agent;
plant metabolite		00low000000
solanesol
0
nonaprenol;
primary alcohol		plant metabolite00low000000
riddelliine n-oxide
0
diol;
macrocyclic lactone;
olefinic compound;
organic heterotricyclic compound;
primary alcohol;
pyrrolizine alkaloid;
tertiary alcohol;
tertiary amine oxide		carcinogenic agent;
genotoxin;
human xenobiotic metabolite;
Jacobaea metabolite;
mutagen;
rat metabolite		00low000000
everolimus
0
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
primary alcohol;
secondary alcohol		anticoronaviral agent;
antineoplastic agent;
geroprotector;
immunosuppressive agent;
mTOR inhibitor		00low000000
tuberonic acid
0
cyclopentanones;
homoallylic alcohol;
oxo monocarboxylic acid;
primary alcohol		jasmonates;
plant metabolite		00low000000
sd 0006
0
monochlorobenzenes;
N-acylpiperidine;
primary alcohol;
pyrazoles;
pyrimidines		00low000000
fty 720p
0
monoalkyl phosphate;
primary alcohol;
primary amino compound		antineoplastic agent;
immunosuppressive agent;
sphingosine-1-phosphate receptor agonist		00low000000
sch 51344
0
aromatic amine;
aromatic ether;
primary alcohol;
pyrazoloquinoline;
secondary amino compound		antineoplastic agent00low000000
3-epi-fagomine
0
amino monosaccharide;
hydroxypiperidine;
primary alcohol;
secondary alcohol;
secondary amino compound;
triol		EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor;
EC 3.2.1.23 (beta-galactosidase) inhibitor;
plant metabolite		00low000000
(+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside
0
beta-D-glucoside;
dimethoxybenzene;
lignan;
monosaccharide derivative;
polyphenol;
primary alcohol;
tetralins		antibacterial agent;
antifungal agent;
metabolite		00low000000
3,5-dimethoxy-4-hydroxybenzyl alcohol-4-O-beta-D-glucopyranoside
0
aromatic ether;
benzyl alcohols;
beta-D-glucoside;
monosaccharide derivative;
primary alcohol		antineoplastic agent;
metabolite		00low000000
2,3-dihydro-3beta-methoxy withaferin A
0
27-hydroxy steroid;
4-hydroxy steroid;
delta-lactone;
epoxy steroid;
ergostanoid;
primary alcohol;
secondary alcohol;
withanolide		metabolite;
plant metabolite		00low000000
tedizolid
0
carbamate ester;
organofluorine compound;
oxazolidinone;
primary alcohol;
pyridines;
tetrazoles		antimicrobial agent;
drug metabolite;
protein synthesis inhibitor		00low000000
PF-00835231
0
aromatic ether;
indolecarboxamide;
L-leucine derivative;
primary alcohol;
pyrrolidin-2-ones;
secondary carboxamide		anticoronaviral agent;
drug metabolite;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor		00low000000
lyoniresinol
0
dimethoxybenzene;
lignan;
polyphenol;
primary alcohol;
tetralins		antineoplastic agent;
metabolite		00low000000
GDC-0879
0
indanes;
ketoxime;
primary alcohol;
pyrazoles;
pyridines		antineoplastic agent;
B-Raf inhibitor		00low000000
sarpagine
0
indole alkaloid;
phenols;
primary alcohol;
secondary amino compound;
tertiary amino compound		00low000000
a-factor (streptomyces)
0
butan-4-olide;
primary alcohol		metabolite00low000000
dihydroconiferyl alcohol glucoside
0
beta-D-glucoside;
monomethoxybenzene;
monosaccharide derivative;
primary alcohol		plant metabolite00low000000
2,3-dihydrowithaferin A
0
27-hydroxy steroid;
4-hydroxy steroid;
delta-lactone;
epoxy steroid;
ergostanoid;
primary alcohol;
secondary alcohol;
withanolide		plant metabolite00low000000
azd 1152-hqpa
0
anilide;
monofluorobenzenes;
primary alcohol;
pyrazoles;
quinazolines;
secondary amino compound;
secondary carboxamide;
tertiary amino compound		antineoplastic agent;
Aurora kinase inhibitor		00low000000
pamapimod
0
aromatic amine;
aromatic ether;
difluorobenzene;
diol;
primary alcohol;
pyridopyrimidine;
secondary amino compound		antirheumatic drug;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
vanchrobactin
0
catechols;
dipeptide;
guanidines;
monocarboxylic acid;
primary alcohol;
triol		bacterial metabolite;
marine metabolite;
siderophore		00low000000
decarbamylsaxitoxin
0
alkaloid;
guanidines;
ketone hydrate;
paralytic shellfish toxin;
primary alcohol;
pyrrolopurine		bacterial metabolite;
marine metabolite;
neurotoxin;
toxin;
xenobiotic		00low000000
tricin 4'-o-(threo-beta-guaiacylglyceryl) ether
0
dimethoxybenzene;
flavonolignan;
polyphenol;
primary alcohol;
secondary alcohol		plant metabolite00low000000
n(alpha)-acetylfusarinines
0
2,5-diketopiperazines;
acetamides;
carboxylic ester;
homoallylic alcohol;
hydroxamic acid;
primary alcohol		siderophore00low000000
(R)-DRF053
0
2,6-diaminopurines;
phenylpyridine;
primary alcohol;
secondary amino compound		EC 2.7.11.22 (cyclin-dependent kinase) inhibitor00low000000
GDC-0623
0
hydroxamic acid ester;
imidazopyridine;
monofluorobenzenes;
organoiodine compound;
primary alcohol;
secondary amino compound;
substituted aniline		antineoplastic agent;
apoptosis inducer;
EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor		00low000000
2,3-dihydro-3beta-O-sulfate withaferin A
0
27-hydroxy steroid;
4-hydroxy steroid;
delta-lactone;
epoxy steroid;
ergostanoid;
primary alcohol;
steroid sulfate;
withanolide		antineoplastic agent;
metabolite;
plant metabolite		00low000000
stemmadenine
0
Aspidosperma alkaloid;
methyl ester;
monoterpenoid indole alkaloid;
organic heterotetracyclic compound;
primary alcohol		plant metabolite00low000000
vinylamycin
0
cyclodepsipeptide;
macrocycle;
primary alcohol		antibacterial agent;
antimicrobial agent;
metabolite		00low000000
bacteriohopane-32-ol
0
pentacyclic triterpenoid;
primary alcohol		00low000000
myriaporone 3
0
beta-hydroxy ketone;
epoxide;
lactol;
oxanes;
primary alcohol;
secondary alcohol		antineoplastic agent;
metabolite		00low000000
cyclooctatin
0
carbotricyclic compound;
diterpenoid;
primary alcohol;
secondary alcohol;
tertiary alcohol		bacterial metabolite;
EC 3.1.1.5 (lysophospholipase) inhibitor		00low000000
entecavir
0
2-aminopurines;
oxopurine;
primary alcohol;
secondary alcohol		antiviral drug;
EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor		00low000000
althiomycin
0
1,3-thiazoles;
aldoxime;
ether;
gamma-lactam;
pentapeptide;
peptide antibiotic;
primary alcohol;
pyrroline;
secondary carboxamide;
tertiary carboxamide		antibacterial agent;
bacterial metabolite;
protein synthesis inhibitor		00low000000
mirodenafil
0
aromatic ether;
N-alkylpiperazine;
primary alcohol;
pyrrolopyrimidine;
sulfonamide		EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor;
vasodilator agent		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
formic acid
0
monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent		00low000000
octanoic acid
0
medium-chain fatty acid;
straight-chain saturated fatty acid		antibacterial agent;
Escherichia coli metabolite;
human metabolite		00low000000
mandelic acid
0
2-hydroxy monocarboxylic acid;
benzenes		antibacterial agent;
human xenobiotic metabolite		00low000000
oxyquinoline
0
monohydroxyquinolineantibacterial agent;
antifungal agrochemical;
antiseptic drug;
iron chelator		00low000000
alexidine
0
biguanidesantibacterial agent00low000000
azelaic acid
0
alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		antibacterial agent;
antineoplastic agent;
dermatologic drug;
plant metabolite		00low000000
carbonyl cyanide m-chlorophenyl hydrazone
0
hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore		00low000000
chelerythrine
0
benzophenanthridine alkaloid;
organic cation		antibacterial agent;
antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor		00low000000
chlorhexidine
0
biguanides;
monochlorobenzenes		antibacterial agent;
antiinfective agent		00low000000
chloroxine
0
monohydroxyquinoline;
organochlorine compound		antibacterial agent;
antifungal drug;
antiseborrheic		00low000000
ciclopirox
0
cyclic hydroxamic acid;
hydroxypyridone antifungal drug;
pyridone		antibacterial agent;
antiseborrheic		00low000000
clioquinol
0
monohydroxyquinoline;
organochlorine compound;
organoiodine compound		antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
antiprotozoal drug;
chelator;
copper chelator		00low000000
decanoic acid
0
medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
anti-inflammatory agent;
antibacterial agent;
human metabolite;
plant metabolite;
volatile oil component		00low000000
dichlorvos
0
alkenyl phosphate;
dialkyl phosphate;
organochlorine acaricide;
organophosphate insecticide		anthelminthic drug;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor		00low000000
ebselen
0
benzoselenazoleanti-inflammatory drug;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 3.1.3.25 (inositol-phosphate phosphatase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 3.5.4.1 (cytosine deaminase) inhibitor;
EC 5.1.3.2 (UDP-glucose 4-epimerase) inhibitor;
enzyme mimic;
ferroptosis inhibitor;
genotoxin;
hepatoprotective agent;
neuroprotective agent;
radical scavenger		00low000000
gentian violet
0
iminium ionantibacterial agent;
antifungal agent		00low000000
heptachlor
0
cyclodiene organochlorine insecticideagrochemical;
antibacterial agent;
antifungal agent;
GABA-gated chloride channel antagonist;
persistent organic pollutant		00low000000
hexachlorophene
0
bridged diphenyl fungicide;
polyphenol;
trichlorobenzene		acaricide;
antibacterial agent;
antifungal agrochemical;
antiseptic drug		00low000000
beta-thujaplicin
0
cyclic ketone;
enol;
monoterpenoid		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiplasmodial drug;
plant metabolite		00low000000
iodoquinol
0
monohydroxyquinoline;
organoiodine compound		antiamoebic agent;
antibacterial agent;
antiprotozoal drug;
antiseptic drug		00low000000
lauric acid
0
medium-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
antibacterial agent;
plant metabolite		00low000000
naled
0
dialkyl phosphate;
organobromine compound;
organochlorine compound;
organophosphate insecticide		acaricide;
agrochemical;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor		00low000000
resorcinol monoacetate
0
phenols;
phenyl acetates		antibacterial agent;
dermatologic drug		00low000000
sulfamethoxazole
0
isoxazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
antiinfective agent;
antimicrobial agent;
drug allergen;
EC 1.1.1.153 [sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)] inhibitor;
EC 2.5.1.15 (dihydropteroate synthase) inhibitor;
environmental contaminant;
epitope;
P450 inhibitor;
xenobiotic		00low000000
sulfanilamide
0
substituted aniline;
sulfonamide antibiotic;
sulfonamide		antibacterial agent;
drug allergen;
EC 4.2.1.1 (carbonic anhydrase) inhibitor		00low000000
triclosan
0
aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols		antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic		00low000000
cloxacillin
0
penicillin allergen;
penicillin;
semisynthetic derivative		antibacterial agent;
antibacterial drug		00low000000
oxacillin
0
penicillinantibacterial agent;
antibacterial drug		00low000000
tert-butylhydroperoxide
0
alkyl hydroperoxideantibacterial agent;
oxidising agent		00low000000
pyocyanine
0
iminium betaine;
phenazines		antibacterial agent;
bacterial metabolite;
biological pigment;
virulence factor		00low000000
acriflavine chloride
0
organic chloride saltantibacterial agent;
antiseptic drug;
carcinogenic agent;
histological dye;
intercalator		00low000000
acetopyrrothine
0
acetamides;
dithiolopyrrolone antibiotic		angiogenesis inhibitor;
antibacterial agent;
antifungal agent;
antineoplastic agent;
bacterial metabolite;
chelator;
EC 2.7.7.6 (RNA polymerase) inhibitor;
marine metabolite;
protein synthesis inhibitor;
toxin		00low000000
gramine
0
aminoalkylindole;
indole alkaloid;
tertiary amino compound		antibacterial agent;
antiviral agent;
plant metabolite;
serotonergic antagonist		00low000000
proflavine
0
aminoacridinesantibacterial agent;
antiseptic drug;
carcinogenic agent;
chromophore;
intercalator		00low000000
allyl alcohol
0
primary allylic alcohol;
propenol		antibacterial agent;
fungicide;
herbicide;
insecticide;
plant metabolite		00low000000
1-hexanol
0
hexanol;
primary alcohol		alarm pheromone;
antibacterial agent;
fragrance;
plant metabolite		00low000000
benzethonium chloride
0
aromatic ether;
chloride salt;
quaternary ammonium salt		antibacterial agent;
antifungal agent;
antiseptic drug;
antiviral agent;
disinfectant		00low000000
ethyl acetoacetate
0
ethyl esterantibacterial agent;
flavouring agent;
plant metabolite		00low000000
diazooxonorleucine
0
amino acid zwitterion;
diazo compound;
ketone;
non-proteinogenic L-alpha-amino acid		analgesic;
antibacterial agent;
antimetabolite;
antineoplastic agent;
antiviral agent;
apoptosis inducer;
bacterial metabolite;
EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor;
EC 3.5.1.2 (glutaminase) inhibitor;
EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor;
EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor;
EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor;
EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor;
glutamine antagonist		00low000000
cloflucarban
0
monochlorobenzenes;
phenylureas		antibacterial agent00low000000
naphthazarin
0
hydroxy-1,4-naphthoquinoneacaricide;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
geroprotector;
plant metabolite		00low000000
physcione
0
dihydroxyanthraquinoneanti-inflammatory agent;
antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
hepatoprotective agent;
metabolite		00low000000
6-methoxybenzoxazolinone
0
aromatic ether;
benzoxazole		antibacterial agent;
anticonvulsant;
antifungal agent;
muscle relaxant;
plant metabolite		00low000000
dazomet
0
dithiocarbamic ester;
thiadiazinane		antibacterial agent;
antifungal agrochemical;
herbicide;
nematicide		00low000000
gentian violet
0
organic chloride saltanthelminthic drug;
antibacterial agent;
antifungal agent;
antiseptic drug;
histological dye		00low000000
4-methyl-1-(1-methylethyl)-3-cyclohexen-1-ol
0
terpineol;
tertiary alcohol		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiparasitic agent;
apoptosis inducer;
plant metabolite;
volatile oil component		00low000000
malachite green
0
organic chloride saltantibacterial agent;
antifungal drug;
carcinogenic agent;
environmental contaminant;
fluorochrome;
histological dye;
teratogenic agent		00low000000
brilliant green
0
organic hydrogensulfate saltantibacterial agent;
antiseptic drug;
environmental contaminant;
fluorochrome;
histological dye;
poison		00low000000
isovanillic acid
0
methoxybenzoic acid;
monohydroxybenzoic acid		antibacterial agent;
plant metabolite		00low000000
sulfaethoxypyridazine
0
sulfonamideantibacterial agent00low000000
nitrapyrin
0
chloropyridineagrochemical;
antibacterial agent;
nitrification inhibitor		00low000000
glaucine
0
aporphine alkaloid;
organic heterotetracyclic compound;
polyether;
tertiary amino compound		antibacterial agent;
antineoplastic agent;
antitussive;
muscle relaxant;
NF-kappaB inhibitor;
plant metabolite;
platelet aggregation inhibitor;
rat metabolite		00low000000
dodine
0
acetate salt;
aliphatic nitrogen antifungal agent		antibacterial agent;
antifungal agrochemical		00low000000
5-methoxyindoleacetic acid
0
aromatic ether;
indole-3-acetic acids		antibacterial agent;
Brassica napus metabolite;
carcinogenic agent;
human urinary metabolite;
marine xenobiotic metabolite;
rat metabolite		00low000000
3-phenylbutyric acid
0
benzenes;
monocarboxylic acid		antibacterial agent;
bacterial xenobiotic metabolite		00low000000
methylene bis(thiocyanate)
0
thiocyanatesantibacterial agent;
fungicide		00low000000
pyoluteorin
0
aromatic ketone;
beta-hydroxy ketone;
diol;
organochlorine compound;
organochlorine pesticide;
polyketide;
pyrroles;
resorcinols		antibacterial agent;
antifungal agent;
apoptosis inducer;
bacterial metabolite;
marine metabolite		00low000000
2-n-octyl-4-isothiazolin-3-one
0
1,2-thiazolesantibacterial agent;
antifungal agrochemical;
environmental contaminant;
xenobiotic		00low000000
sodium azide
0
inorganic sodium saltantibacterial agent;
explosive;
mitochondrial respiratory-chain inhibitor;
mutagen		00low000000
nigericin
0
polycyclic etherantibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore		00low000000
tobramycin
0
amino cyclitol glycosideantibacterial agent;
antimicrobial agent;
toxin		00low000000
baicalin
0
dihydroxyflavone;
glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative		antiatherosclerotic agent;
antibacterial agent;
anticoronaviral agent;
antineoplastic agent;
antioxidant;
cardioprotective agent;
EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
ferroptosis inhibitor;
neuroprotective agent;
non-steroidal anti-inflammatory drug;
plant metabolite;
prodrug		00low000000
allicin
0
botanical anti-fungal agent;
sulfoxide		antibacterial agent00low000000
bicozamycin
0
azabicycloalkane;
bridged compound		antibacterial agent;
antidiarrhoeal drug;
antiinfective agent		00low000000
toxoflavin
0
carbonyl compound;
pyrimidotriazine		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
toxin;
virulence factor;
Wnt signalling inhibitor		00low000000
viridicatin
0
hydroxyquinolineantibacterial agent;
Aspergillus metabolite;
marine metabolite;
Penicillium metabolite		00low000000
aureothricin
0
dithiolopyrrolone antibiotic;
secondary carboxamide		angiogenesis inhibitor;
antibacterial agent;
bacterial metabolite;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
arbekacin
0
aminoglycoside;
kanamycins		antibacterial agent;
antibacterial drug;
antimicrobial agent;
protein synthesis inhibitor		00low000000
enrofloxacin
0
cyclopropanes;
N-alkylpiperazine;
N-arylpiperazine;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone		antibacterial agent;
antimicrobial agent;
antineoplastic agent		00low000000
oxetanocin a
0
diol;
nucleoside analogue;
oxetanes;
primary alcohol		anti-HIV agent;
antibacterial agent;
bacterial metabolite		00low000000
nucleocidin
0
6-aminopurines;
adenosines;
diol;
organofluorine compound;
sulfamate ester		antibacterial agent;
bacterial metabolite;
nucleoside antibiotic;
protein synthesis inhibitor;
trypanocidal drug		00low000000
neamine
0
2,6-dideoxy-alpha-D-glucoside;
aminoglycoside		antibacterial agent00low000000
sigmoidin a
0
4'-hydroxyflavanones;
tetrahydroxyflavanone		anti-inflammatory agent;
anti-obesity agent;
antibacterial agent;
metabolite;
radical scavenger		00low000000
brazilin
0
catechols;
organic heterotetracyclic compound;
tertiary alcohol		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
biological pigment;
hepatoprotective agent;
histological dye;
NF-kappaB inhibitor;
plant metabolite		00low000000
furanomycin
0
dihydrofuran;
non-proteinogenic L-alpha-amino acid		antibacterial agent;
antimicrobial agent;
bacterial metabolite		00low000000
arjunolic acid
0
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		antibacterial agent;
antifungal agent;
antioxidant;
metabolite		00low000000
ethyl protocatechuate
0
catechols;
ethyl ester		antibacterial agent;
antioxidant;
apoptosis inducer;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
plant metabolite		00low000000
terreic acid
0
arene epoxide;
diketone;
monohydroxy-1,4-benzoquinones;
tertiary alpha-hydroxy ketone		antibacterial agent;
antineoplastic agent;
Aspergillus metabolite;
EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
mycotoxin		00low000000
prunin protein, prunus
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
dihydroxyflavanone;
flavanone 7-O-beta-D-glucoside;
monosaccharide derivative		antibacterial agent;
antilipemic drug;
hypoglycemic agent;
metabolite		00low000000
atromentin
0
dihydroxy-1,4-benzoquinones;
polyphenol		antibacterial agent;
anticoagulant;
antineoplastic agent;
apoptosis inducer;
biological pigment;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
fungal metabolite		00low000000
dehydroacetic acid
0
ketone;
pyran-2,4-dione		antibacterial agent;
fungicide;
plasticiser		00low000000
senegalensin
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
trihydroxyflavanone		antibacterial agent;
plant metabolite		00low000000
rubiadin
0
dihydroxyanthraquinoneantibacterial agent;
antioxidant;
hepatoprotective agent;
plant metabolite		00low000000
soranjidiol
0
dihydroxyanthraquinoneantibacterial agent;
plant metabolite		00low000000
hypothiocyanite ion
0
one-carbon compound;
sulfur oxoacid		antibacterial agent;
antifungal agent;
antiviral agent;
human metabolite;
oxidising agent;
rat metabolite		00low000000
ilomastat
0
hydroxamic acid;
L-tryptophan derivative;
N-acyl-amino acid		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
EC 3.4.24.24 (gelatinase A) inhibitor;
neuroprotective agent		00low000000
7-aminocholesterol
0
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
primary amino compound		antibacterial agent00low000000
pyrrolomycin a
0
antibiotic antifungal agent;
C-nitro compound;
organochlorine compound;
pyrroles		antibacterial agent;
bacterial metabolite		00low000000
u-47929
0
alkaloid;
aziridines;
dipeptide;
pyrrolidines		antibacterial agent;
bacterial metabolite;
DNA synthesis inhibitor		00low000000
actinodaphine
0
aporphine alkaloid;
aromatic ether;
organic heteropentacyclic compound;
phenols;
secondary amino compound		antibacterial agent;
antifungal agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite;
platelet aggregation inhibitor;
topoisomerase inhibitor		00low000000
my 12-62c
0
monohydroxyquinoline;
quinolone		antibacterial agent;
iron chelator;
metabolite;
signalling molecule		00low000000
anacardic acid
0
hydroxy monocarboxylic acid;
hydroxybenzoic acid		anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
apoptosis inducer;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
neuroprotective agent;
plant metabolite		00low000000
5-o-methyllicoricidin
0
aromatic ether;
hydroxyisoflavans;
methoxyisoflavan		antibacterial agent;
plant metabolite		00low000000
bromodeoxytopsentin
0
aromatic ketone;
bromoindole;
imidazoles;
indole alkaloid		antibacterial agent;
EC 2.7.1.40 (pyruvate kinase) inhibitor;
marine metabolite		00low000000
vestitone
0
(3R)-2'-hydroxyisoflavanones;
hydroxyisoflavanone;
methoxyisoflavanone		antibacterial agent;
metabolite		00low000000
conessine
0
steroid alkaloid;
tertiary amino compound		antibacterial agent;
antimalarial;
H3-receptor antagonist;
plant metabolite		00low000000
meropenem
0
alpha,beta-unsaturated monocarboxylic acid;
carbapenemcarboxylic acid;
organic sulfide;
pyrrolidinecarboxamide		antibacterial agent;
antibacterial drug;
drug allergen		00low000000
griseofulvin
0
1-benzofurans;
antibiotic antifungal drug;
benzofuran antifungal drug;
organochlorine compound;
oxaspiro compound		antibacterial agent;
Penicillium metabolite		00low000000
ferruginol
0
abietane diterpenoid;
carbotricyclic compound;
meroterpenoid;
phenols		antibacterial agent;
antineoplastic agent;
plant metabolite;
protective agent		00low000000
sodium arsenite
0
arsenic molecular entity;
inorganic sodium salt		antibacterial agent;
antifungal agent;
antineoplastic agent;
carcinogenic agent;
herbicide;
insecticide;
rodenticide		00low000000
surfactin c
0
cyclodepsipeptide;
lipopeptide antibiotic;
macrocyclic lactone		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiviral agent;
metabolite;
platelet aggregation inhibitor;
surfactant		00low000000
dibekacin
0
kanamycinsantibacterial agent;
protein synthesis inhibitor		00low000000
gancaonin I
0
1-benzofurans;
aromatic ether;
resorcinols		antibacterial agent;
plant metabolite		00low000000
6,8-diprenylgenistein
0
7-hydroxyisoflavonesantibacterial agent;
plant metabolite		00low000000
glycyrin
0
aromatic ether;
coumarins;
hydroxyisoflavans		antibacterial agent;
metabolite;
plant metabolite		00low000000
licoricidin
0
aromatic ether;
hydroxyisoflavans;
methoxyisoflavan		antibacterial agent;
plant metabolite		00low000000
licocoumarone
0
1-benzofurans;
aromatic ether;
resorcinols		antibacterial agent;
apoptosis inducer;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite		00low000000
methyl cinnamate
0
methyl cinnamateantibacterial agent;
fungal metabolite;
nematicide;
plant metabolite		00low000000
o-methyl threonine
0
ether;
L-threonine derivative;
non-proteinogenic L-alpha-amino acid		antibacterial agent;
bleaching agent		00low000000
helvolic acid
0
3-oxo-Delta(1) steroid;
acetate ester;
monocarboxylic acid;
steroid acid		antibacterial agent;
fungal metabolite;
mycotoxin		00low000000
manool
0
labdane diterpenoid;
tertiary alcohol		antibacterial agent;
antineoplastic agent;
plant metabolite		00low000000
chuangxinmycin
0
indole alkaloid;
monocarboxylic acid;
thiinoindole		antibacterial agent;
antimicrobial agent;
bacterial metabolite;
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor		00low000000
fraxetin
0
aromatic ether;
hydroxycoumarin		anti-inflammatory agent;
antibacterial agent;
antimicrobial agent;
antioxidant;
apoptosis inducer;
apoptosis inhibitor;
Arabidopsis thaliana metabolite;
hepatoprotective agent;
hypoglycemic agent		00low000000
quercetin
0
7-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger		00low000000
apigetrin
0
beta-D-glucoside;
dihydroxyflavone;
glycosyloxyflavone;
monosaccharide derivative		antibacterial agent;
metabolite;
non-steroidal anti-inflammatory drug		00low000000
kaempferol
0
7-hydroxyflavonol;
flavonols;
tetrahydroxyflavone		antibacterial agent;
geroprotector;
human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
plant metabolite		00low000000
2-hexenal, z-isomer
0
2-hexenalantibacterial agent;
flavouring agent;
plant metabolite		00low000000
isobavachalcone
0
chalcones;
polyphenol		antibacterial agent;
metabolite;
platelet aggregation inhibitor		00low000000
baicalein
0
trihydroxyflavoneangiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger		00low000000
morin
0
7-hydroxyflavonol;
pentahydroxyflavone		angiogenesis modulating agent;
anti-inflammatory agent;
antibacterial agent;
antihypertensive agent;
antineoplastic agent;
antioxidant;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
hepatoprotective agent;
metabolite;
neuroprotective agent		00low000000
caffeic acid phenethyl ester
0
alkyl caffeate esteranti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
antiviral agent;
immunomodulator;
metabolite;
neuroprotective agent		00low000000
acteoside
0
catechols;
cinnamate ester;
disaccharide derivative;
glycoside;
polyphenol		anti-inflammatory agent;
antibacterial agent;
antileishmanial agent;
neuroprotective agent;
plant metabolite		00low000000
veronicastroside
0
disaccharide derivative;
glycosyloxyflavone;
neohesperidoside;
trihydroxyflavone		antibacterial agent;
metabolite		00low000000
plaunotol
0
diterpenoid;
primary alcohol		anti-ulcer drug;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
nephroprotective agent;
plant metabolite;
vulnerary		00low000000
sofalcone
0
aromatic ether;
chalcones;
monocarboxylic acid		anti-ulcer drug;
antibacterial agent;
gastrointestinal drug;
plant metabolite		00low000000
fortimicin a
0
amino cyclitol glycoside;
aminoglycoside antibiotic;
diol;
monocarboxylic acid amide;
primary amino compound		antibacterial agent;
metabolite		00low000000
cannabigerol
0
phytocannabinoid;
resorcinols		anti-inflammatory agent;
antibacterial agent;
antioxidant;
appetite enhancer;
cannabinoid receptor agonist;
neuroprotective agent;
plant metabolite		00low000000
kaempferol 3-o-rhamnoside
0
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		anti-inflammatory agent;
antibacterial agent;
plant metabolite		00low000000
3,3'-di-o-methylquercetin
0
3'-methoxyflavones;
dimethoxyflavone;
trihydroxyflavone		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite		00low000000
cudraflavone c
0
tetrahydroxyflavoneantibacterial agent;
antineoplastic agent;
plant metabolite		00low000000
oridonin
0
cyclic hemiketal;
enone;
ent-kaurane diterpenoid;
organic heteropentacyclic compound;
secondary alcohol		angiogenesis inhibitor;
anti-asthmatic agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
plant metabolite		00low000000
bay 11-7085
0
benzenes;
nitrile;
sulfone		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
autophagy inducer;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
ferroptosis inducer;
NF-kappaB inhibitor		00low000000
5,4'-dihydroxy-7,3'-dimethoxyflavone
0
dihydroxyflavone;
dimethoxyflavone		anti-allergic agent;
anti-inflammatory agent;
antibacterial agent;
antioxidant;
melanin synthesis inhibitor;
plant metabolite		00low000000
ochnaflavone
0
aromatic ether;
biflavonoid;
hydroxyflavone		anti-inflammatory agent;
antiatherogenic agent;
antibacterial agent;
EC 3.1.1.4 (phospholipase A2) inhibitor;
leukotriene antagonist;
plant metabolite		00low000000
4-hydroxycordoin
0
aromatic ether;
chalcones;
polyphenol		anti-inflammatory agent;
antibacterial agent;
plant metabolite		00low000000
linolenyl alcohol
0
long-chain primary fatty alcoholantibacterial agent00low000000
aurachin c
0
C-type aurachin;
hydroxylamines;
organic heterobicyclic compound;
quinolone		antibacterial agent;
bacterial metabolite;
EC 1.8.5.4 (sulfide:quinone reductase) inhibitor		00low000000
asukamycin
0
enamide;
epoxide;
organic heterobicyclic compound;
polyketide;
secondary carboxamide;
tertiary alcohol		antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite		00low000000
kalimantacin a
0
alpha,beta-unsaturated monocarboxylic acid;
carbamate ester;
fatty acid derivative;
secondary carboxamide		antibacterial agent;
antimicrobial agent;
bacterial metabolite		00low000000
sophoraflavanone a
0
(2S)-flavan-4-one;
4'-hydroxyflavanones;
trihydroxyflavanone		antibacterial agent;
antineoplastic agent;
metabolite		00low000000
cholesteryl arachidonate
0
cholesteryl icosatetraenoateantibacterial agent;
mouse metabolite		00low000000
aureothin
0
4-pyranones;
C-nitro compound;
ketene acetal;
olefinic compound;
oxolanes		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiparasitic agent;
bacterial metabolite;
EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor		00low000000
platensimycin
0
aromatic amide;
cyclic ether;
cyclic ketone;
dihydroxybenzoic acid;
monocarboxylic acid amide;
polycyclic cage		antibacterial agent;
antimicrobial agent;
bacterial metabolite;
EC 2.3.1.85 (fatty acid synthase) inhibitor		00low000000
chlorhexidine
0
biguanides;
monochlorobenzenes		antibacterial agent;
antiinfective agent		00low000000
fr 148083
0
aromatic ether;
macrolide;
phenols;
secondary alcohol;
secondary alpha-hydroxy ketone		antibacterial agent;
antineoplastic agent;
metabolite;
NF-kappaB inhibitor		00low000000
etimicin
0
amino cyclitol glycoside;
aminoglycoside antibiotic		antibacterial agent00low000000
rubraxanthone
0
aromatic ether;
polyphenol;
xanthones		antibacterial agent;
antineoplastic agent;
metabolite		00low000000
holomycin
0
acetamides;
dithiolopyrrolone antibiotic		antibacterial agent;
antineoplastic agent;
bacterial metabolite;
chelator;
EC 2.7.7.6 (RNA polymerase) inhibitor;
marine metabolite		00low000000
fonsecinone a
0
aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol		antibacterial agent;
Aspergillus metabolite		00low000000
lactonamycin
0
gamma-lactone;
organic heterohexacyclic compound;
phenols;
trideoxyhexose derivative		antibacterial agent;
antimicrobial agent;
metabolite		00low000000
(+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside
0
beta-D-glucoside;
dimethoxybenzene;
lignan;
monosaccharide derivative;
polyphenol;
primary alcohol;
tetralins		antibacterial agent;
antifungal agent;
metabolite		00low000000
baci-im
0
homodetic cyclic peptide;
polypeptide;
zwitterion		antibacterial agent;
antimicrobial agent		00low000000
laurinterol
0
organobromine compound;
phenols;
sesquiterpenoid		antibacterial agent;
apoptosis inducer;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
metabolite		00low000000
diversonol
0
phenols;
tertiary alcohol		antibacterial agent;
metabolite		00low000000
5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine
0
1,3-thiazoles;
C-nitro compound;
organic sulfide;
primary amino compound;
thiadiazoles		antibacterial agent;
c-Jun N-terminal kinase inhibitor		00low000000
cytotrienin a
0
cyclopropanecarboxylate ester;
ether;
hydroquinones;
lactam;
macrocycle;
secondary alcohol		antibacterial agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
metabolite		00low000000
3,6-diamino-10-methylacridinium chloride hydrochloride
0
hydrochlorideantibacterial agent;
antiseptic drug;
carcinogenic agent;
intercalator		00low000000
tyrocidine
0
homodetic cyclic peptide;
macrocycle;
peptide antibiotic		antibacterial agent;
bacterial metabolite		00low000000
thiazomycin
0
heterodetic cyclic peptideantibacterial agent;
antimicrobial agent;
bacterial metabolite		00low000000
platencin
0
aromatic amide;
cyclic ketone;
dihydroxybenzoic acid;
monocarboxylic acid amide;
polycyclic cage		antibacterial agent;
antimicrobial agent;
bacterial metabolite;
EC 2.3.1.85 (fatty acid synthase) inhibitor		00low000000
bromophycolide a
0
diterpenoid;
macrolide;
organobromine compound;
phenols;
tertiary alcohol		anti-HIV agent;
antibacterial agent;
antifungal agent;
antimalarial;
antineoplastic agent;
metabolite		00low000000
marinopyrrole a
0
aromatic ketone;
organochlorine compound;
phenols;
pyrroles		antibacterial agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
marine metabolite		00low000000
6-tuliposide b
0
6-O-acyl-D-glucose;
enoate ester		antibacterial agent;
antifungal agent;
plant metabolite		00low000000
etnangien
0
hydroxy monocarboxylic acid;
macrolide antibiotic		antibacterial agent;
metabolite		00low000000
entrectinib
0
benzamides;
difluorobenzene;
indazoles;
N-methylpiperazine;
oxanes;
secondary amino compound;
secondary carboxamide		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
bacillaene
0
enamine;
monocarboxylic acid amide;
polyene antibiotic;
polyketide;
secondary alcohol		antibacterial agent;
antimicrobial agent;
bacterial metabolite		00low000000
dicranin
0
acetylenic fatty acid;
long-chain fatty acid;
straight-chain fatty acid;
trienoic fatty acid		antibacterial agent;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
metabolite		00low000000
tropodithietic acid
0
cyclic ketone;
monocarboxylic acid;
organic disulfide;
organic heterobicyclic compound;
organosulfur heterocyclic compound		antibacterial agent;
bacterial metabolite;
marine metabolite;
signalling molecule;
toxin		00low000000
jadomycin b
0
glycoside;
jadomycin;
organic heteropentacyclic compound		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
Aurora kinase inhibitor;
bacterial metabolite		00low000000
fumimycin
0
1-benzofurans;
dicarboxylic acid monoamide;
gamma-lactone;
monocarboxylic acid;
polyphenol		antibacterial agent;
Aspergillus metabolite;
EC 3.5.1.88 (peptide deformylase) inhibitor		00low000000
novobiocin
0
carbamate ester;
ether;
hexoside;
hydroxycoumarin;
monocarboxylic acid amide;
monosaccharide derivative;
phenols		antibacterial agent;
antimicrobial agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
Escherichia coli metabolite;
hepatoprotective agent		00low000000
vinylamycin
0
cyclodepsipeptide;
macrocycle;
primary alcohol		antibacterial agent;
antimicrobial agent;
metabolite		00low000000
epidermin
0
macrocycle;
type A lantibiotic		antibacterial agent;
metabolite		00low000000
surfactin A
0
cyclodepsipeptide;
lipopeptide antibiotic;
macrocyclic lactone		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiviral agent;
metabolite;
surfactant		00low000000
phleomycin d1
0
bi-1,3-thiazole;
chelate-forming peptide;
disaccharide derivative;
glycopeptide;
guanidines		antibacterial agent;
antifungal agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite		00low000000
boromycin
0
macrodiolide;
macrolide antibiotic;
organoboron compound;
oxaspiro compound;
zwitterion		anti-HIV agent;
antibacterial agent;
bacterial metabolite		00low000000
mastoparan x
0
mastoparans;
peptidyl amide		antibacterial agent00low000000
teixobactin
0
cyclodepsipeptide;
macrocycle;
peptide antibiotic		antibacterial agent00low000000
aurachin a
0
A-type aurachin;
furoquinoline;
quinoline N-oxide;
tertiary alcohol		antibacterial agent;
bacterial metabolite		00low000000
tirapazamine
0
aromatic amine;
benzotriazines;
N-oxide		antibacterial agent;
antineoplastic agent;
apoptosis inducer		00low000000
indolmycin
0
1,3-oxazoles;
indoles;
secondary amino compound		antibacterial agent;
antimicrobial agent;
bacterial metabolite;
EC 6.1.1.2 (tryptophan--tRNA ligase) inhibitor		00low000000
althiomycin
0
1,3-thiazoles;
aldoxime;
ether;
gamma-lactam;
pentapeptide;
peptide antibiotic;
primary alcohol;
pyrroline;
secondary carboxamide;
tertiary carboxamide		antibacterial agent;
bacterial metabolite;
protein synthesis inhibitor		00low000000
undecylprodigiosin
0
alkaloid;
aromatic ether;
tripyrrole		antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent		00low000000
iberin
0
isothiocyanate;
sulfoxide		apoptosis inducer;
plant metabolite;
quorum sensing inhibitor		00low000000
2,3,4-trihydroxbenzophenone
0
benzenetriol;
hydroxybenzophenone		drug metabolite;
EC 1.14.18.1 (tyrosinase) inhibitor;
human urinary metabolite;
quorum sensing inhibitor;
rat metabolite		00low000000
n-acetyltyramine
0
acetamides;
tyramines		animal metabolite;
Aspergillus metabolite;
bacterial metabolite;
marine metabolite;
quorum sensing inhibitor		00low000000
resveratrol
0
resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger		00low000000
laurolitsine
0
aporphine alkaloid;
aromatic ether;
phenols		HIV-1 integrase inhibitor;
metabolite		00low000000
australifungin
0
carbobicyclic compound;
enol;
enone;
secondary alcohol		antifungal agent;
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor;
HIV-1 integrase inhibitor;
metabolite		00low000000
jtk-303
0
aromatic ether;
monochlorobenzenes;
organofluorine compound;
quinolinemonocarboxylic acid;
quinolone		HIV-1 integrase inhibitor00low000000
chicoric acid
0
organooxygen compoundgeroprotector;
HIV-1 integrase inhibitor		00low000000
complestatin
0
cyclic ether;
heterodetic cyclic peptide;
indoles;
organic heterobicyclic compound;
organochlorine compound;
peptide antibiotic;
polyphenol		anti-HIV-1 agent;
antimicrobial agent;
HIV-1 integrase inhibitor;
metabolite		00low000000
neuroprotectin a
0
cyclic ether;
heterodetic cyclic peptide;
indoles;
organochlorine compound;
polyphenol		HIV-1 integrase inhibitor;
metabolite		00low000000
integric acid
0
carboxylic ester;
cyclic ketone;
dioxo monocarboxylic acid;
enal;
enone;
eremophilane sesquiterpenoid		HIV-1 integrase inhibitor;
metabolite		00low000000
raltegravir
0
1,2,4-oxadiazole;
dicarboxylic acid amide;
hydroxypyrimidine;
monofluorobenzenes;
pyrimidone;
secondary carboxamide		antiviral drug;
HIV-1 integrase inhibitor		00low000000
gsk1265744
0
difluorobenzene;
monocarboxylic acid amide;
organic heterotricyclic compound;
secondary carboxamide		HIV-1 integrase inhibitor00low000000
dolutegravir
0
difluorobenzene;
monocarboxylic acid amide;
organic heterotricyclic compound;
secondary carboxamide		HIV-1 integrase inhibitor00low000000
bictegravir
0
monocarboxylic acid amide;
organic heterotetracyclic compound;
secondary carboxamide;
trifluorobenzene		HIV-1 integrase inhibitor00low000000
4-hydroxyphenylacetic acid
0
monocarboxylic acid;
phenols		fungal metabolite;
human metabolite;
mouse metabolite;
plant metabolite		00low000000
indoleacetamide
0
indoles;
monocarboxylic acid amide;
N-acylammonia		bacterial metabolite;
fungal metabolite;
plant metabolite		00low000000
gamma-guanidinobutyric acid
0
guanidines;
monocarboxylic acid;
zwitterion		fungal metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		00low000000
itaconic acid
0
dicarboxylic acid;
dicarboxylic fatty acid;
olefinic compound		fungal metabolite;
human metabolite		00low000000
theophylline
0
dimethylxanthineadenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent		00low000000
caffeine
0
purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic		00low000000
2,5-dihydroxybenzoic acid
0
dihydroxybenzoic acidEC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
fungal metabolite;
human metabolite;
MALDI matrix material;
mouse metabolite		00low000000
muscimol
0
alkaloid;
isoxazoles;
primary amino compound		fungal metabolite;
GABA agonist;
oneirogen;
psychotropic drug		00low000000
psilocin
0
hydroxyindoles;
phenols;
tertiary amino compound;
tryptamine alkaloid		drug metabolite;
fungal metabolite;
hallucinogen;
human xenobiotic metabolite;
serotonergic agonist		00low000000
urethane
0
carbamate esterfungal metabolite;
mutagen		00low000000
methyl n-methylanthranilate
0
benzoate ester;
methyl ester;
secondary amino compound;
substituted aniline		animal metabolite;
fungal metabolite;
plant metabolite		00low000000
veratryl alcohol
0
benzyl alcohols;
dimethoxybenzene;
primary alcohol		fungal metabolite00low000000
4-hydroxyacetophenone
0
monohydroxyacetophenonefungal metabolite;
mouse metabolite;
plant metabolite		00low000000
acrylonitrile
0
aliphatic nitrile;
volatile organic compound		antifungal agent;
carcinogenic agent;
fungal metabolite;
mutagen;
polar aprotic solvent		00low000000
4-hydroxyphenylethanol
0
phenolsanti-arrhythmia drug;
antioxidant;
cardiovascular drug;
fungal metabolite;
geroprotector;
plant metabolite;
protective agent		00low000000
psilocybin
0
organic phosphate;
tertiary amino compound;
tryptamine alkaloid		fungal metabolite;
hallucinogen;
prodrug;
serotonergic agonist		00low000000
nonadecanoic acid
0
long-chain fatty acid;
straight-chain saturated fatty acid		fungal metabolite00low000000
3-methylfuran
0
furans;
volatile organic compound		Aspergillus metabolite;
environmental contaminant;
fungal metabolite;
Penicillium metabolite;
plant metabolite		00low000000
gamma-dodecalactone
0
gamma-lactonebacterial metabolite;
fungal metabolite;
volatile oil component		00low000000
1-octen-3-ol
0
alkenyl alcohol;
medium-chain fatty alcohol		antimicrobial agent;
fungal metabolite;
insect attractant;
volatile oil component		00low000000
norsolorinic acid
0
polyketide;
tetrahydroxyanthraquinone		fungal metabolite00low000000
2-ethylhexanal
0
saturated fatty aldehydebacterial xenobiotic metabolite;
fungal metabolite		00low000000
mevastatin
0
2-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite		00low000000
norharman
0
beta-carbolines;
mancude organic heterotricyclic parent		fungal metabolite;
marine metabolite		00low000000
cephalosporin c
0
cephalosporinfungal metabolite00low000000
sulfur
0
elemental sulfur;
homomonocyclic compound		bacterial metabolite;
fungal metabolite		00low000000
orsellinic acid
0
dihydroxybenzoic acid;
resorcinols		fungal metabolite;
marine metabolite;
metabolite		00low000000
nebularine
0
purine ribonucleoside;
purines D-ribonucleoside		fungal metabolite00low000000
1,8-dihydroxynaphthalene
0
naphthalenediolfungal metabolite00low000000
siccanin
0
organic heteropentacyclic compoundantifungal drug;
fungal metabolite		00low000000
rubrofusarin
0
aromatic ether;
benzochromenone;
phenols;
polyketide		biological pigment;
EC 1.14.18.1 (tyrosinase) inhibitor;
fungal metabolite		00low000000
5-hydroxybenzofuran-2-one
0
1-benzofurans;
aromatic alcohol		antifungal agent;
fungal metabolite		00low000000
5-hydroxymethyl-2-furoic acid
0
aromatic primary alcohol;
furoic acid		bacterial xenobiotic metabolite;
fungal metabolite;
human urinary metabolite;
nematicide		00low000000
fibrinogen
0
iditolfungal metabolite00low000000
3-hydroxybutyric acid
0
3-hydroxybutyric acid;
ketone body		fungal metabolite;
human metabolite;
pheromone		00low000000
orotidine
0
nucleoside;
pyrimidinemonocarboxylic acid;
uridines		bacterial metabolite;
fungal metabolite;
plant metabolite		00low000000
2'-o-methyladenosine
0
adenosines;
ether		fungal metabolite00low000000
ergosine
0
ergot alkaloidfungal metabolite00low000000
acromelic acid a
0
pyridone;
pyrrolidinecarboxylic acid;
tricarboxylic acid		fungal metabolite;
neurotoxin;
NMDA receptor agonist		00low000000
trapoxin a
0
epoxide;
homodetic cyclic peptide;
ketone		antineoplastic agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
fungal metabolite		00low000000
deoxyfuconojirimycin
0
hydroxypiperidine;
triol		fungal metabolite00low000000
emodin anthrone
0
anthracenone;
phenols		fungal metabolite00low000000
saintopin
0
tetracenequinonesantineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
fungal metabolite;
intercalator		00low000000
cercosporamide
0
dibenzofurans;
methyl ketone;
monocarboxylic acid amide;
polyphenol		antifungal agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite;
phytotoxin		00low000000
baeocystin
0
organic phosphate;
secondary amino compound;
tryptamine alkaloid		fungal metabolite;
hallucinogen		00low000000
albicanol
0
carbobicyclic compound;
homoallylic alcohol;
primary alcohol;
sesquiterpenoid		antifeedant;
antifungal agent;
antineoplastic agent;
fungal metabolite;
mammalian metabolite;
marine metabolite;
plant metabolite		00low000000
ml 236a
0
2-pyranones;
carbobicyclic compound;
hexahydronaphthalenes;
polyketide;
secondary alcohol		antiatherosclerotic agent;
anticholesteremic drug;
antilipemic drug;
antimicrobial agent;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
fungal metabolite		00low000000
2,5-dihydroxybenzyl alcohol
0
aromatic primary alcohol;
phenols		antineoplastic agent;
antioxidant;
apoptosis inhibitor;
fungal metabolite		00low000000
3-octanone
0
dialkyl ketoneantifeedant;
biomarker;
fungal metabolite;
human urinary metabolite;
insect attractant;
plant metabolite;
toxin		00low000000
lenticin
0
amino-acid betaine;
indole alkaloid;
L-tryptophan derivative		fungal metabolite;
plant metabolite;
xenobiotic		00low000000
ergonovine
0
ergot alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound;
primary alcohol;
secondary amino compound;
tertiary amino compound		diagnostic agent;
fungal metabolite;
oxytocic;
toxin		00low000000
ergosterol
0
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite		00low000000
eicosapentaenoic acid
0
icosapentaenoic acid;
omega-3 fatty acid		anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical		00low000000
aphidicolin
0
tetracyclic diterpenoidantimicrobial agent;
antimitotic;
antineoplastic agent;
antiviral drug;
apoptosis inducer;
Aspergillus metabolite;
DNA synthesis inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
fungal metabolite		00low000000
sordaricin
0
3-oxo monocarboxylic acid;
aldehyde;
bridged compound;
primary alcohol;
tetracyclic diterpenoid		antifungal agent;
fungal metabolite		00low000000
averufin
0
cyclic ketal;
organic heteropentacyclic compound;
polyketide;
polyphenol		fungal metabolite00low000000
rhodotorulic acid
0
2,5-diketopiperazines;
hydroxamic acid;
L-ornithine derivative		fungal metabolite;
siderophore		00low000000
beauvericin
0
cyclodepsipeptideantibiotic insecticide;
antifungal agent;
antineoplastic agent;
apoptosis inhibitor;
fungal metabolite;
ionophore;
mycotoxin;
P450 inhibitor		00low000000
8,11,14-eicosatrienoic acid
0
fatty acid 20:3;
long-chain fatty acid		fungal metabolite;
human metabolite;
nutraceutical		00low000000
canthaxanthin
0
carotenonebiological pigment;
Escherichia coli metabolite;
food colouring;
fungal metabolite		00low000000
zearalenone
0
macrolide;
resorcinols		fungal metabolite;
mycoestrogen		00low000000
norlichexanthone
0
polyphenol;
xanthones		antimalarial;
fungal metabolite		00low000000
orobol
0
7-hydroxyisoflavonesanti-inflammatory agent;
fungal metabolite;
plant metabolite;
radical scavenger		00low000000
ellagic acid
0
catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent		00low000000
t-2 toxin
0
acetate ester;
organic heterotetracyclic compound;
trichothecene		apoptosis inducer;
cardiotoxic agent;
DNA synthesis inhibitor;
environmental contaminant;
fungal metabolite;
mycotoxin;
neurotoxin		00low000000
glycitein
0
7-hydroxyisoflavone;
methoxyisoflavone		fungal metabolite;
phytoestrogen;
plant metabolite		00low000000
ergothioneine
0
1,3-dihydroimidazole-2-thiones;
amino-acid betaine;
L-histidine derivative;
sulfur-containing amino acid		antioxidant;
chelator;
fungal metabolite;
plant metabolite;
xenobiotic metabolite		00low000000
alternariol monomethyl ether
0
aromatic ether;
benzochromenone		antifungal agent;
fungal metabolite;
mycotoxin		00low000000
iditol
0
iditolfungal metabolite;
human metabolite		00low000000
poricoic acid a
0
dicarboxylic acid;
secondary alcohol;
tricyclic triterpenoid		fungal metabolite00low000000
poricoic acid g
0
dicarboxylic acid;
secondary alcohol;
tricyclic triterpenoid		fungal metabolite00low000000
mevalonolactone
0
4-hydroxy-4-methyloxan-2-onefungal metabolite;
plant metabolite		00low000000
ascofuranone
0
dihydroxybenzaldehyde;
meroterpenoid;
monochlorobenzenes;
olefinic compound;
resorcinols;
sesquiterpenoid;
tetrahydrofuranone		angiogenesis inhibitor;
antilipemic drug;
antineoplastic agent;
antiprotozoal drug;
fungal metabolite		00low000000
mucidin
0
enoate ester;
enol ether		antifungal agent;
fungal metabolite		00low000000
squalestatin 1
0
acetate ester;
cyclic ketal;
oxabicycloalkane;
polyketide;
tertiary alcohol;
tricarboxylic acid		EC 2.5.1.21 (squalene synthase) inhibitor;
fungal metabolite		00low000000
thermozymocidin
0
alpha-amino fatty acid;
hydroxy monocarboxylic acid;
non-proteinogenic alpha-amino acid;
sphingoid		antifungal agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor;
fungal metabolite;
immunosuppressive agent		00low000000
acuminatin
0
1-benzofurans;
dimethoxybenzene;
neolignan;
olefinic compound;
ring assembly		fungal metabolite;
plant metabolite		00low000000
strobilurin b
0
enoate ester;
enol ether;
methoxyacrylate strobilurin antifungal agent;
monochlorobenzenes;
monomethoxybenzene		antifungal agent;
fungal metabolite;
mitochondrial cytochrome-bc1 complex inhibitor		00low000000
ergosta-4,6,8(14),22-tetraen-3-one
0
3-oxo-Delta(4) steroid;
ergostanoid		fungal metabolite00low000000
fumagillin
0
antibiotic antifungal drug;
carboxylic ester;
dicarboxylic acid monoester;
meroterpenoid;
organooxygen heterocyclic antibiotic;
spiro-epoxide		angiogenesis inhibitor;
antibacterial drug;
antimicrobial agent;
antiprotozoal drug;
fungal metabolite;
methionine aminopeptidase 2 inhibitor		00low000000
altenusin
0
aromatic ether;
carboxybiphenyl;
catechols;
hydroxybiphenyls;
polyphenol		antifungal agent;
fungal metabolite		00low000000
ebericol
0
14alpha-methyl steroid;
3beta-sterol;
tetracyclic triterpenoid		fungal metabolite00low000000
tmc-95a
0
indoles;
lactam;
macrocycle;
phenols;
secondary alcohol;
tertiary alcohol		antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
fungal metabolite;
proteasome inhibitor		00low000000
monacolin j
0
2-pyranones;
carbobicyclic compound;
hexahydronaphthalenes;
polyketide;
secondary alcohol		antimicrobial agent;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
fungal metabolite		00low000000
trachyspic acid
0
oxaspiro compound;
tricarboxylic acid		EC 3.2.1.166 (heparanase) inhibitor;
fungal metabolite		00low000000
yw 3548
0
olefinic compound;
terpene lactone;
tertiary alcohol		fungal metabolite;
glycerophosphoinositol synthesis inhibitor		00low000000
hypothemycin
0
aromatic ether;
diol;
enone;
epoxide;
macrolide;
phenols;
polyketide;
secondary alpha-hydroxy ketone		antifungal agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite		00low000000
HT-2 toxin
0
acetate ester;
organic heterotetracyclic compound;
trichothecene		apoptosis inducer;
fungal metabolite		00low000000
tmc-95b
0
indoles;
lactam;
macrocycle;
phenols;
secondary alcohol;
tertiary alcohol		antimicrobial agent;
antineoplastic agent;
fungal metabolite;
proteasome inhibitor		00low000000
sporothriolide
0
furofuran;
gamma-lactone		antifungal agent;
fungal metabolite		00low000000
ascochlorin
0
cyclohexanones;
dihydroxybenzaldehyde;
meroterpenoid;
monochlorobenzenes;
olefinic compound;
resorcinols;
sesquiterpenoid		angiogenesis inhibitor;
antifungal agent;
antineoplastic agent;
antiprotozoal drug;
fungal metabolite		00low000000
zaragozic acid c
0
acetate ester;
cyclic ketal;
oxabicycloalkane;
polyketide;
tertiary alcohol;
tricarboxylic acid		EC 2.5.1.21 (squalene synthase) inhibitor;
fungal metabolite		00low000000
monascin
0
alpha,beta-unsaturated ketone;
gamma-lactone;
organic heterotricyclic compound;
polyketide		antilipemic drug;
antineoplastic agent;
fungal metabolite;
PPARgamma agonist		00low000000
monascorubrin
0
azaphilone;
enone;
gamma-lactone;
polyketide;
triketone		anti-inflammatory agent;
antineoplastic agent;
biological pigment;
food colouring;
fungal metabolite;
Hsp90 inhibitor		00low000000
5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4h-1-benzopyran-4-one
0
alkaloid;
chromones;
hydroxypiperidine;
resorcinols;
tertiary amino compound		anti-inflammatory agent;
anti-ulcer drug;
anticholesteremic drug;
antileishmanial agent;
antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
fungal metabolite;
plant metabolite		00low000000
ganodermadiol
0
3beta-sterol;
primary allylic alcohol;
tetracyclic triterpenoid		antiviral agent;
fungal metabolite;
hepatoprotective agent		00low000000
(3E,9E)-5,6-Dihydroxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-3,9,12-triene-2,18-dione
0
cytochalasinfungal metabolite00low000000
prosomatostatin
0
heterodetic cyclic peptide;
peptide hormone		fungal metabolite;
mouse metabolite;
rat metabolite		00low000000
depudecin
0
polyketideEC 3.5.1.98 (histone deacetylase) inhibitor;
fungal metabolite		00low000000
diorcinol
0
aromatic ether;
phenols		fungal metabolite;
marine metabolite;
metabolite		00low000000
antroquinonol d
0
enol ether;
enone;
secondary alcohol		antineoplastic agent;
fungal metabolite		00low000000
hispidin
0
2-pyranones;
catechols		antioxidant;
EC 2.7.11.13 (protein kinase C) inhibitor;
fungal metabolite		00low000000
asperfuranone
0
2-benzofurans;
cyclic ketone;
diol;
polyketide;
secondary alcohol;
tertiary alcohol;
tertiary alpha-hydroxy ketone		antineoplastic agent;
fungal metabolite		00low000000
bassianolide
0
cyclodepsipeptide;
cyclooctadepsipeptide		antineoplastic agent;
fungal metabolite;
insecticide		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
beta-thujaplicin
0
cyclic ketone;
enol;
monoterpenoid		antibacterial agent;
antifungal agent;
antineoplastic agent;
antiplasmodial drug;
plant metabolite		00low000000
1-hexanol
0
hexanol;
primary alcohol		alarm pheromone;
antibacterial agent;
fragrance;
plant metabolite		00low000000
oxetanocin a
0
diol;
nucleoside analogue;
oxetanes;
primary alcohol		anti-HIV agent;
antibacterial agent;
bacterial metabolite		00low000000
plaunotol
0
diterpenoid;
primary alcohol		anti-ulcer drug;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
nephroprotective agent;
plant metabolite;
vulnerary		00low000000
(+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside
0
beta-D-glucoside;
dimethoxybenzene;
lignan;
monosaccharide derivative;
polyphenol;
primary alcohol;
tetralins		antibacterial agent;
antifungal agent;
metabolite		00low000000
vinylamycin
0
cyclodepsipeptide;
macrocycle;
primary alcohol		antibacterial agent;
antimicrobial agent;
metabolite		00low000000
althiomycin
0
1,3-thiazoles;
aldoxime;
ether;
gamma-lactam;
pentapeptide;
peptide antibiotic;
primary alcohol;
pyrroline;
secondary carboxamide;
tertiary carboxamide		antibacterial agent;
bacterial metabolite;
protein synthesis inhibitor		00low000000
australifungin
0
carbobicyclic compound;
enol;
enone;
secondary alcohol		antifungal agent;
EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor;
HIV-1 integrase inhibitor;
metabolite		00low000000
veratryl alcohol
0
benzyl alcohols;
dimethoxybenzene;
primary alcohol		fungal metabolite00low000000
albicanol
0
carbobicyclic compound;
homoallylic alcohol;
primary alcohol;
sesquiterpenoid		antifeedant;
antifungal agent;
antineoplastic agent;
fungal metabolite;
mammalian metabolite;
marine metabolite;
plant metabolite		00low000000
ergonovine
0
ergot alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound;
primary alcohol;
secondary amino compound;
tertiary amino compound		diagnostic agent;
fungal metabolite;
oxytocic;
toxin		00low000000
sordaricin
0
3-oxo monocarboxylic acid;
aldehyde;
bridged compound;
primary alcohol;
tetracyclic diterpenoid		antifungal agent;
fungal metabolite		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
succinic acid
1
alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid		anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent		1993199331.0low001000
carbonyl cyanide p-trifluoromethoxyphenylhydrazone
1
aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore		1992199232.0low001000
adenosine diphosphate
1
adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate		fundamental metabolite;
human metabolite		1993199331.0low001000
decalin
4
ortho-fused bicyclic hydrocarbonsolvent201420217.8medium000031
pyrroles
2
pyrrole;
secondary amine		1999201417.5low001010
propadiene
1
allenes201620168.0low000010
pyrrolidine
1
azacycloalkane;
pyrrolidines;
saturated organic heteromonocyclic parent		2013201311.0low000010
alkenes
2
201620187.0low000020
nigericin
1
polycyclic etherantibacterial agent;
antimicrobial agent;
bacterial metabolite;
potassium ionophore		1992199232.0low001000
lovastatin
1
delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug		2010201014.0low000100
simvastatin
1
delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic)		EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug		2010201014.0low000100
mevastatin
1
2-pyranones;
carboxylic ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring)		antifungal agent;
apoptosis inducer;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
fungal metabolite;
Penicillium metabolite		2010201014.0low000100
pyrophosphate
1
diphosphate ion1989198935.0low010000
valinomycin
1
cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore		1992199232.0low001000
zearalenone
1
macrolide;
resorcinols		fungal metabolite;
mycoestrogen		2002200222.0low000100
integric acid
1
carboxylic ester;
cyclic ketone;
dioxo monocarboxylic acid;
enal;
enone;
eremophilane sesquiterpenoid		HIV-1 integrase inhibitor;
metabolite		1999199925.0medium001000
tenuazonic acid
1
201520159.0low000010
reutericyclin
1
201520159.0low000010
tetramic acid
5
2013201510.2medium000050
delaminomycin a
1
2010201014.0medium000100
fusarisetin a
2
2013201410.5high000020
alchivemycin a
1
2010201014.0high000100
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Infections, Staphylococcal0
1
202220222.0high000001
Invasiveness, Neoplasm0
1
2010201014.0high000100
Staphylococcal Infections0
1
202220222.0high000001