Page last updated: 2024-09-28

Enophthalmos

Recession of the eyeball into the orbit.

Synonyms(1)

Synonym
Enophthalmos

Research Excerpts

Overview

ExcerptReference
"Enophthalmos is usually a consequence of orbital trauma resulting in a blowout fracture of the orbital floor."( Kawahara, T; Miyaguchi, M; Sakai, S, 1992)
"Relative enophthalmos is often cited as a causative factor in the development of involutional entropion."( Hammer, BJ; Kersten, RC; Kulwin, DR, 1997)
"Enophthalmos is one manifestation that may require corrective treatment."( Boyd, JH; Holds, J; Yaffee, K, 1998)
"Late surgery for enophthalmos is technically more difficult but is not associated with poorer functional or cosmetic results."( Inkster, CF; Leatherbarrow, B; Madill, SA; Maloof, AJ; Ng, SG, 2001)
"Enophthalmos is defined as a backward, and usually downward, displacement of the globe into the bony orbit."( Clauser, L; Galiè, M; Pagliaro, F; Tieghi, R, 2008)
"Late enophthalmos is a well-known consequence of large orbital floor fractures."( Cestari, DM; Gopal, H; Montezuma, SR; Savar, A; Torun, N; Turalba, A, 2008)
"Enophthalmos is a complex and unpredictable condition to treat secondarily, and this is likely to remain a difficult challenge."( Holmes, S, 2011)
"Enophthalmos is defined as backward, usually downward, displacement of the globe into the bony orbit."( Kim, YB; Nam, SM; Park, ES; Shin, HS, 2011)
"Enophthalmos is corrected mostly through reducing the enlarged orbit volume by identifying intact bone edges and spanning the defect with an implant or autogenous graft."( Kang, SJ; Kim, JW, 2012)
"The enophthalmos is a rare cause of consultation in medical practice."( Balbo, NS; Lahoz Ibaceta, MJ; Smith, RJ, 2014)
"Enophthalmos is a challenging surgical problem to correct."( Adenuga, P; Brown, M; Gargesha, M; Guyuron, B; Lee, M; Molavi, S; Varghai, D; Zwiebel, S, 2014)
"Enophthalmos is the posterior displacement of the ocular globe within the bony orbit."( Daizo, H; Kishibe, M; Shimada, K; Yamashita, A; Yamashita, M, 2015)
"Enophthalmos is a severe complication of primary reconstruction of orbital floor fractures."( Badiali, G; Marchetti, C; Pizzigallo, A; Tarsitano, A, 2016)
"Posttraumatic enophthalmos is a relatively common problem following orbitozygomatic fractures."( Eun, SC; Hong, SH; Kim, TH; Park, IH, 2017)
"Enophthalmos is caused by an increase of orbital volume after blowout fracture and is one of the most critical complications of such fractures, but is often masked by swelling soon after injury."( Inoue, Y; Okumoto, T; Onishi, S; Sugiura, K; Yamada, H, 2017)
"Enophthalmos is one of the most distressing complications of orbital fracture, and when faced with a blowout fracture, plastic surgeons often find it difficult to determine the need for surgical correction."( Kim, SW; Mo, YW; Shin, HK, 2020)
"Enophthalmos is one of the most distressing complications of blowout orbital fractures."( Lee, WJ; Mo, YW; Ryu, DH; Shin, HK, 2023)

Context

ExcerptReference
"Post-traumatic enophthalmos has a complex pathogenesis, resulting from injuries to the bony walls of the orbit or to the intraorbital contents."( Aldegheri, A; Gola, R; Tsakoniatis, N; Waller, PY, 1992)
"Non-traumatic enophthalmos has a wide variety of clinical presentations and may be the first manifestation of a number of local or systemic conditions."( Athanasiov, PA; Prabhakaran, VC; Selva, D, 2008)
"Enophthalmos has many causes, and serious post-traumatic cases indicate the need for operation."( Nightingale, CL; Shakib, K, 2019)

Treatment

ExcerptReference
"Despite adequate treatment, enophthalmos due to intraconjunctival corticosteroid injection and enlargement of the bony orbit after trauma remains a frequent complication."( Aygit, AC; Cakir, B; Omur-Okten, O; Yalcin, O, 2012)

Research

Studies (371)

TimeframeStudies, This Condition (%)All Conditions %
pre-19909 (2.43)23.3326
1990's72 (19.41)12.5806
2000's85 (22.91)18.1394
2010's147 (39.62)28.8240
2020's58 (15.63)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
lactic acid0medium21
formaldehyde0low20
nickel0low10
acetazolamide0low10
fluconazole0low10
guaifenesin0low10
haloperidol0low10
2-propanol0low20
letrozole0low10
prednisolone0low20
thyroxine0low10
pilocarpine0low10
chloramphenicol0low10
sucrose0low10
ethylene oxide0low10
methylmethacrylate0low10
caprolactam0low10
fluorometholone0low10
durapatite0medium91
titanium0medium532
gold0low10
phosphoric acid, trisodium salt0low10
tricalcium phosphate0low20
calcium sulfate0low10
propiconazole0medium3159
itraconazole0low10
topotecan0low10
triazoles0low10
htr composite0low10
melphalan0low10
travoprost0low10
phenylephrine hydrochloride0low80
bimatoprost0low30
cloprostenol0low10
latanoprost0low10
aluminum oxide0low10
cyclosporine0low10
eye0medium161

Protein Targets (604)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit3003
RAR-related orphan receptor gamma110011
GLI family zinc finger 3130013
AR protein130013
aldehyde dehydrogenase 1 family, member A16006
retinoic acid nuclear receptor alpha variant 1130013
retinoid X nuclear receptor alpha8008
estrogen nuclear receptor alpha160016
peroxisome proliferator-activated receptor delta5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
activating transcription factor 63003
v-jun sarcoma virus 17 oncogene homolog (avian)7007
Histone H2A.x4004
thyroid hormone receptor beta isoform a4004
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 1100010
lamin isoform A-delta105005
Voltage-dependent calcium channel gamma-2 subunit6006
Glutamate receptor 26006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase3003
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
thioredoxin reductase7007
GALC protein3003
nuclear receptor subfamily 1, group I, member 3100010
cytochrome P450 family 3 subfamily A polypeptide 4100010
glucocorticoid receptor [Homo sapiens]8008
estrogen-related nuclear receptor alpha130013
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A3003
Carbonic anhydrase0101
euchromatic histone-lysine N-methyltransferase 27007
Bloom syndrome protein isoform 12002
geminin8008
peripheral myelin protein 225005
survival motor neuron protein isoform d3003
muscleblind-like protein 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi5106
ATP-binding cassette sub-family C member 30909
Multidrug resistance-associated protein 40909
Carbonic anhydrase0101
Solute carrier family 22 member 60202
Carbonic anhydrase 120316
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump013013
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 105110
Carbonic anhydrase 207212
Carbonic anhydrase 20202
Cytochrome P450 1A20101
Carbonic anhydrase 30316
Cathepsin B0101
Cytochrome P450 3A40607
Steryl-sulfatase0202
5-hydroxytryptamine receptor 2C0303
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80101
Cytochrome P450 2D60101
Cytochrome P450 2A60213
Cytochrome P450 2C9 0404
5-hydroxytryptamine receptor 2A0303
Androgen receptor0404
Gamma-aminobutyric acid receptor subunit beta-15106
Translocator protein0101
Gamma-aminobutyric acid receptor subunit delta5106
Gamma-aminobutyric acid receptor subunit gamma-25106
Gamma-aminobutyric acid receptor subunit alpha-55106
Gamma-aminobutyric acid receptor subunit alpha-35106
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60101
Carbonic anhydrase 40416
Carbonic anhydrase 60315
Gamma-aminobutyric acid receptor subunit gamma-15106
Gamma-aminobutyric acid receptor subunit alpha-25106
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10202
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-45106
Gamma-aminobutyric acid receptor subunit gamma-35106
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-65106
Adenosine receptor A2a0101
5-hydroxytryptamine receptor 2B0303
Sodium-dependent serotonin transporter0202
Delta-type opioid receptor0101
Cytochrome P450 2C190101
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Carbonic anhydrase 5A, mitochondrial0417
Carbonic anhydrase0101
Kappa-type opioid receptor0202
Carbonic anhydrase 70315
Carbonic anhydrase0101
D(1A) dopamine receptor1203
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0101
D(2) dopamine receptor0303
Gamma-aminobutyric acid receptor subunit alpha-15106
Gamma-aminobutyric acid receptor subunit beta-35106
Gamma-aminobutyric acid receptor subunit beta-25106
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Fatty-acid amide hydrolase 10101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0202
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 90529
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase 30101
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10202
Renin0101
Carbonic anhydrase 0101
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130214
GABA theta subunit5106
Canalicular multispecific organic anion transporter 10808
Carbonic anhydrase 40202
Carbonic anhydrase 150203
Acidic mammalian chitinase0101
Carbonic anhydrase 130304
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon5106
Carbonic anhydrase 0101
Carbonic anhydrase 140316
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0417
SMAD family member 23003
SMAD family member 33003
caspase 7, apoptosis-related cysteine protease3003
caspase-33003
interleukin 81001
TDP1 protein8008
EWS/FLI fusion protein7007
farnesoid X nuclear receptor6006
pregnane X nuclear receptor110011
G7007
cytochrome P450 2D65005
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
aryl hydrocarbon receptor5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
thyroid hormone receptor beta isoform 27007
DNA polymerase iota isoform a (long)3003
streptokinase A precursor0011
lethal factor (plasmid)2002
Dihydroxyacetone phosphate acyltransferase0001
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 7007
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Cellular tumor antigen p539009
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Inositol hexakisphosphate kinase 17007
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial7007
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Thromboxane A2 receptor 0112
Prostaglandin E2 receptor EP1 subtype0112
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin F2-alpha receptor0213
Prostaglandin E2 receptor EP3 subtype0112
Prostaglandin E2 receptor EP2 subtype0101
Prostacyclin receptor0101
Prostaglandin D2 receptor0101
Chain A, BCL-2-RELATED PROTEIN A10011
acetylcholinesterase3003
apical membrane antigen 1, AMA12002
unnamed protein product0101
chromobox protein homolog 14004
transcriptional regulator ERG isoform 31001
heat shock protein HSP 90-alpha isoform 20002
cytochrome P450 3A4 isoform 15005
bcl-2-like protein 11 isoform 10011
Histone deacetylase 30101
Rap guanine nucleotide exchange factor 33003
Chymotrypsinogen A0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Heme oxygenase 1 0101
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10304
Lanosterol 14-alpha demethylase0112
Aromatase0303
Cytochrome P450 11B1, mitochondrial0202
Cytochrome P450 11B2, mitochondrial0202
ATP-dependent translocase ABCB10101
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0101
Histone deacetylase 40101
Cytochrome P450 1440022
Steroid C26-monooxygenase0022
Steroid C26-monooxygenase0022
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
TAR DNA-binding protein 435005
Histone deacetylase 10101
Lanosterol 14-alpha demethylase0112
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
14-alpha sterol demethylase 0011
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
heat shock protein 90, putative0002
likely tRNA 2'-phosphotransferase0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
progesterone receptor6006
nuclear receptor subfamily 1, group I, member 22002
lysosomal alpha-glucosidase preproprotein2002
huntingtin isoform 21001
flap endonuclease 12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
nuclear receptor ROR-gamma isoform 14004
DNA polymerase kappa isoform 12002
Nuclear receptor subfamily 1 group I member 20022
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
glp-1 receptor, partial4004
15-lipoxygenase, partial2002
ATAD5 protein, partial1001
Fumarate hydratase4004
NFKB1 protein, partial1001
Thrombopoietin1001
thyroid stimulating hormone receptor2002
regulator of G-protein signaling 42002
nonstructural protein 12002
polyprotein4004
glucocerebrosidase2002
Adenylate cyclase type 1 0101
thyroid stimulating hormone receptor3003
cytochrome P450 2D6 isoform 11001
peripheral myelin protein 22 isoform 11001
cytochrome P450 2C9 precursor2002
D(1A) dopamine receptor1001
potassium voltage-gated channel subfamily H member 2 isoform d2002
serine/threonine-protein kinase mTOR isoform 11001
transient receptor potential cation channel subfamily V member 11001
muscarinic acetylcholine receptor M11001
Cocaine esterase0101
Solute carrier family 22 member 1 0101
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
UDP-glucuronosyltransferase 1A90102
Voltage-dependent L-type calcium channel subunit alpha-1F0101
5-hydroxytryptamine receptor 40202
Potassium channel subfamily K member 20101
Albumin0011
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10101
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20213
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M10405
Muscarinic acetylcholine receptor M30405
Muscarinic acetylcholine receptor M40405
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M50405
Muscarinic acetylcholine receptor M50303
Alpha-2A adrenergic receptor0202
Beta-2 adrenergic receptor0202
Muscarinic acetylcholine receptor M20405
Muscarinic acetylcholine receptor M10325
Angiotensin-converting enzyme0101
Integrin alpha-40101
D(2) dopamine receptor0215
Alpha-1B adrenergic receptor0202
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70102
Alpha-2B adrenergic receptor0202
Beta-1 adrenergic receptor0101
Alpha-2C adrenergic receptor0202
D0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0202
Alpha-2B adrenergic receptor0101
D(2) dopamine receptor0202
Muscarinic acetylcholine receptor M30101
D(1A) dopamine receptor0203
D(4) dopamine receptor0215
D(1B) dopamine receptor0203
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0101
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0202
Sodium-dependent noradrenaline transporter 0202
Sodium-dependent dopamine transporter0101
5-hydroxytryptamine receptor 3A0101
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 1F0101
Histamine H1 receptor0202
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 7 0101
C-8 sterol isomerase0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0101
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
Alpha-1B adrenergic receptor0101
Mu-type opioid receptor0213
Glutamate receptor ionotropic, NMDA 1 0101
D(3) dopamine receptor0215
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80101
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0202
Histamine H2 receptor3004
5-hydroxytryptamine receptor 2A0101
5-hydroxytryptamine receptor 60101
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20202
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
Spike glycoprotein5005
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
Potassium voltage-gated channel subfamily H member 20202
5-hydroxytryptamine receptor 40101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sodium channel protein type 9 subunit alpha0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Zinc finger protein 6640101
Glutamate receptor ionotropic, NMDA 2D0101
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0202
Adenylyl cyclase 7 0101
Glutamate receptor ionotropic, NMDA 3B0101
D0101
ATPase family AAA domain-containing protein 54004
Sodium channel protein type 2 subunit alpha0101
Ataxin-24004
Sigma non-opioid intracellular receptor 10202
Transient receptor potential cation channel subfamily V member 40101
Sodium channel protein type 3 subunit alpha0101
Sigma non-opioid intracellular receptor 10202
Glutamate receptor ionotropic, NMDA 3A0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Transient receptor potential cation channel subfamily V member 20101
Sodium channel protein type 10 subunit alpha0101
ATP-dependent phosphofructokinase2002
estrogen receptor 2 (ER beta)5005
cellular tumor antigen p53 isoform a1001
Integrin beta-31001
Integrin alpha-IIb1001
Chain A, 2-oxoglutarate Oxygenase3003
Microtubule-associated protein tau1001
beta-2 adrenergic receptor2002
mitogen-activated protein kinase 11001
Solute carrier organic anion transporter family member 2A10101
USP1 protein, partial3003
cytochrome P450 2C19 precursor2002
runt-related transcription factor 1 isoform AML1b1001
vitamin D3 receptor isoform VDRA3003
core-binding factor subunit beta isoform 21001
Estrogen receptor0303
Amine oxidase [flavin-containing] A 0101
phosphopantetheinyl transferase2002
GLS protein2002
thioredoxin glutathione reductase2002
Smad31001
Caspase-71001
caspase-31001
importin subunit beta-1 isoform 11001
snurportin-11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Nuclear receptor ROR-gamma2002
Large neutral amino acids transporter small subunit 1 0101
IDH11001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
luciferase0001
nuclear factor erythroid 2-related factor 2 isoform 22002
Fatty acid-binding protein, liver0101
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
pregnane X receptor2002
Chain A, Ferritin light chain1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
Guanine nucleotide-binding protein G1001
chaperonin-containing TCP-1 beta subunit homolog1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
histone acetyltransferase KAT2A isoform 11001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Bile salt export pump0101
Albumin0101
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10001
NPYLR7B0011
tyrosine-protein kinase Yes1001
Solute carrier family 22 member 20101
DNA topoisomerase 10124
DNA topoisomerase 2-alpha0101
DNA topoisomerase 2-beta0101
DNA topoisomerase 10101
Hypoxia-inducible factor 1-alpha0112
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10101
Endothelial PAS domain-containing protein 10011
Broad substrate specificity ATP-binding cassette transporter ABCG20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]