Seroma

Tumor-like sterile accumulation of serum in a tissue, organ, or cavity. It results from a tissue insult and is the product of tissue inflammation. It most commonly occurs following MASTECTOMY.

Synonym
Seroma

Excerpt	Reference
"Seroma is a common complication after mastectomy."	( Askegard-Giesmann, J; Bjarnason, H; Boughey, JC; Degnim, AC; Donohue, JH; Hoskin, TL; Throckmorton, AD, 2008)
"Seroma is a common postoperative complication that arises when serous fluid collects in the space generated following surgeries that require extensive dissection and that create large empty spaces."	( Putnam, D; Zawaneh, PN, 2008)
"Auricular seroma is a cystic swelling filled with serous fluid."	( Naik, CS; Nemade, SV, 2014)
"However, donor site seroma is the most common complication of LD flap reconstruction."	( Chen, Y; Pan, Y; Qu, J; Yang, Y; Zhang, X, 2015)
"Donor-site seroma is the most common complication following latissimus dorsi flap breast reconstruction."	( Duggal, C; Hart, AM; Losken, A; Pinell-White, X, 2017)
"Seroma is a recognized complication encountered at the reconstructed breast and donor site after abdominal-based breast reconstruction."	( Eom, JS; Han, HH; Kim, EK; Lee, YH; Oh, TM; Suh, YC, 2020)
"Postoperative seroma is the most common minor complication after inguinal hernia repair surgery and can have negative consequences."	( Cheng, G; Ge, Y; Gu, H; Liu, J; Shen, W; Zhou, Y, 2023)

Excerpt	Reference
"Successful treatment of the seroma remains a challenge because this disease has a high propensity for recurrence."	( Naik, CS; Nemade, SV, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	18 (15.65)	18.1394
2010's	70 (60.87)	28.8240
2020's	27 (23.48)	9.53

Drug	Relationship Strength	Studies	Trials
citric acid, anhydrous	low	1	0
salicylic acid	low	2	0
lactic acid	low	1	0
dihydroxyacetone	low	1	0
dalteparin	low	1	0
phenytoin	low	1	0
azelastine	low	1	0
baclofen	low	2	0
diclofenac	low	1	0
fluorouracil	low	1	0
gentamicin	low	1	0
hydrochlorothiazide	medium	1	1
lidocaine	low	2	0
nitroglycerin	low	1	0
tranexamic acid	low	6	0
urethane	medium	4	4
methylprednisolone acetate	medium	3	3
lysine	medium	3	3
cephalothin	low	1	0
triamcinolone acetonide	medium	3	1
methylprednisolone	medium	3	3
diatrizoate meglumine	low	1	0
pyrazines	low	2	0
caprolactone	medium	1	1
hematoxylin	low	1	0
eosine yellowish-(ys)	low	1	0
c.i. 42510	medium	1	1
erythromycin	low	1	0
durapatite	low	1	0
vancomycin	medium	1	1
methylprednisolone hemisuccinate	medium	1	1
octyl 2-cyanoacrylate	low	1	0
palladium	medium	1	1
titanium	medium	11	2
argon	low	1	0
chromium	low	1	0
gadolinium	low	1	0
gold	medium	3	1
vanadium	low	1	0
calcium sulfate	low	1	0
trolamine salicylate	low	2	0
titanium dioxide	low	3	0
triamcinolone	medium	4	4
iso-sulfan blue	medium	1	1
fibrinogen	medium	5	2
cobalt	low	1	0
ropivacaine	low	1	0
tetraethylpyrazine	low	2	0
povidone-iodine	low	1	0
fibrin	medium	1	1
epiglucan	medium	1	1
zithromax	low	1	0
picibanil	medium	4	3
polidocanol	low	1	0
morphine	low	2	0
aluminum	low	1	0
chlorhexidine	medium	1	1
indocyanine green	low	3	0
cellulose	medium	1	1
interleukin-8	low	1	0
oxytetracycline, anhydrous	low	1	0
transforming growth factor beta	low	18	0
orabase	low	1	0

Protein Targets (643)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Fumarate hydratase	2	0	0	2
EWS/FLI fusion protein	4	0	0	4
polyprotein	2	0	0	2
ATP-dependent translocase ABCB1	0	4	0	4
Cytochrome P450 3A4	0	6	1	7
Cytochrome P450 2D6	0	3	0	3
Muscarinic acetylcholine receptor M1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Histamine H1 receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Alpha-1A adrenergic receptor	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Histamine H3 receptor	0	1	0	1
thioredoxin reductase	10	0	0	10
phosphopantetheinyl transferase	6	0	0	6
ATAD5 protein, partial	5	0	0	5
NFKB1 protein, partial	2	0	0	2
GLI family zinc finger 3	15	0	0	15
AR protein	14	0	0	14
regulator of G-protein signaling 4	4	0	0	4
67.9K protein	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	11	0	0	11
activating transcription factor 6	2	0	0	2
Bloom syndrome protein isoform 1	3	0	0	3
D(1A) dopamine receptor	1	0	0	1
cytochrome P450 3A4 isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	5	0	0	5
lamin isoform A-delta10	11	0	0	11
Gamma-aminobutyric acid receptor subunit pi	7	1	0	9
ATP-binding cassette sub-family C member 3	0	9	0	9
Multidrug resistance-associated protein 4	0	9	0	9
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Bile salt export pump	0	14	0	14
Gamma-aminobutyric acid receptor subunit beta-1	7	1	0	9
Gamma-aminobutyric acid receptor subunit delta	7	1	0	9
Gamma-aminobutyric acid receptor subunit gamma-2	7	1	1	10
Gamma-aminobutyric acid receptor subunit alpha-5	7	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-3	7	1	0	9
Gamma-aminobutyric acid receptor subunit gamma-1	7	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-2	7	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-4	7	1	0	9
Gamma-aminobutyric acid receptor subunit gamma-3	7	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-6	7	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	7	1	1	10
Gamma-aminobutyric acid receptor subunit beta-3	7	1	0	9
Gamma-aminobutyric acid receptor subunit beta-2	7	1	1	10
GABA theta subunit	7	1	0	9
Canalicular multispecific organic anion transporter 1	0	9	0	9
Gamma-aminobutyric acid receptor subunit epsilon	7	1	0	9
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
ATP-dependent phosphofructokinase	5	0	0	5
TDP1 protein	11	0	0	11
progesterone receptor	7	0	0	7
glucocorticoid receptor [Homo sapiens]	13	0	0	13
retinoid X nuclear receptor alpha	12	0	0	12
estrogen-related nuclear receptor alpha	14	0	0	14
estrogen nuclear receptor alpha	18	0	0	18
peroxisome proliferator activated receptor gamma	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
thyroid hormone receptor beta isoform 2	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	10	0	0	10
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Cellular tumor antigen p53	7	0	0	7
Glutamate receptor 2	6	0	0	6
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	7	0	0	7
Cytochrome P450 1A2	0	3	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
endonuclease IV	3	0	0	3
WRN	3	0	0	3
GLS protein	4	0	0	4
Microtubule-associated protein tau	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	10	0	0	10
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
vitamin D3 receptor isoform VDRA	3	0	0	3
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
heat shock protein beta-1	5	0	0	5
importin subunit beta-1 isoform 1	5	0	0	5
flap endonuclease 1	7	0	0	7
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	5	0	0	5
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	3	0	0	3
DNA polymerase kappa isoform 1	4	0	0	4
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-1	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	2	0	3
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	4	0	0	4
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	1	0	2
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	2	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase VIM-1	0	0	0	1
Solute carrier family 22 member 7	0	1	0	2
phosphoglycerate kinase	3	0	0	3
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
Chain A, Cruzipain	1	0	0	1
Luciferase	5	0	0	5
acid sphingomyelinase	2	0	0	2
interleukin 8	3	0	0	3
acetylcholinesterase	5	0	0	5
PAX8	0	0	0	1
glp-1 receptor, partial	5	0	0	5
15-lipoxygenase, partial	3	0	0	3
pregnane X receptor	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
RAR-related orphan receptor gamma	9	0	0	9
SMAD family member 2	4	0	0	4
USP1 protein, partial	6	0	0	6
SMAD family member 3	4	0	0	4
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
PINK1	1	0	0	1
thyroid stimulating hormone receptor	3	0	0	3
estrogen receptor 2 (ER beta)	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
farnesoid X nuclear receptor	4	0	0	4
pregnane X nuclear receptor	8	0	0	8
G	8	0	0	8
cytochrome P450 2D6	7	0	0	7
glucocerebrosidase	2	0	0	2
Parkin	1	0	0	1
peroxisome proliferator-activated receptor delta	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
heat shock protein 90	0	0	1	1
caspase-3	2	0	0	2
IDH1	7	0	0	7
calcineurin A1, putative	0	0	1	1
aryl hydrocarbon receptor	4	0	0	4
thyroid stimulating hormone receptor	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
Histone H2A.x	5	0	0	5
cytochrome P450 2D6 isoform 1	2	0	0	2
hepatocyte nuclear factor 4-alpha isoform 2	0	2	0	2
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C19 precursor	2	0	0	2
cytochrome P450 2C9 precursor	3	0	0	3
perilipin-5	0	2	0	2
thyroid hormone receptor beta isoform a	6	0	0	6
perilipin-1	0	2	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
transcriptional regulator ERG isoform 3	3	0	0	3
huntingtin isoform 2	3	0	0	3
mitogen-activated protein kinase 1	4	0	0	4
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
protein AF-9 isoform a	0	0	0	1
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
bcl-2-related protein A1	0	1	0	1
urokinase plasminogen activator surface receptor precursor	3	0	0	3
nuclear receptor ROR-gamma isoform 1	5	0	0	5
geminin	16	0	0	16
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	2	0	2
peripheral myelin protein 22	4	0	0	4
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
lethal factor (plasmid)	1	0	0	1
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Interferon beta	10	0	0	10
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
Integrin beta-3	3	0	0	3
72 kDa type IV collagenase	0	2	0	2
Integrin alpha-IIb	3	0	0	3
Matrix metalloproteinase-9	0	1	0	1
Trypanothione reductase	0	1	0	1
Alpha-synuclein	1	1	0	2
Histamine H2 receptor	4	0	0	4
Nuclear receptor ROR-gamma	2	0	0	2
TAR DNA-binding protein 43	3	0	0	3
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Inositol hexakisphosphate kinase 1	8	0	0	8
Multidrug and toxin extrusion protein 1	0	4	0	4
Spermine oxidase	0	1	0	1
cytochrome P450 2C9, partial	8	0	0	8
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
aldehyde dehydrogenase 1 family, member A1	8	0	0	8
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Hsf1 protein	0	0	2	2
chromobox protein homolog 1	10	0	0	10
survival motor neuron protein isoform d	6	0	0	6
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Carbonic anhydrase 1	0	4	0	4
Carbonic anhydrase 2	0	5	0	5
Fatty acid-binding protein, liver	0	1	0	1
Transthyretin	0	0	1	3
Albumin	0	3	3	6
Prostaglandin G/H synthase 1	0	1	0	1
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	6	0	7
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Cytochrome P450 2J2	0	4	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 9	0	3	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
streptokinase A precursor	0	0	2	2
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	3	0	0	3
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
ATP-dependent translocase ABCB1	0	3	0	3
60 kDa chaperonin	0	1	0	1
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
60 kDa heat shock protein, mitochondrial	0	2	0	2
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
10 kDa heat shock protein, mitochondrial	0	2	0	2
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
Cytochrome P450 1B1	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
Lanosterol 14-alpha demethylase	0	1	0	1
50S ribosomal protein L36 2	0	3	1	4
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Thrombopoietin	1	0	0	1
nonstructural protein 1	2	0	0	2
arylsulfatase A	4	0	0	4
peripheral myelin protein 22 isoform 1	4	0	0	4
hemoglobin subunit beta	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Vpr	1	0	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
Epidermal growth factor receptor	0	1	0	1
Amyloid-beta precursor protein	1	0	0	1
Thymidylate synthase	0	1	0	1
Aromatase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
PPM1D protein	3	0	0	3
alkaline phosphatase, intestinal	0	0	1	1
thioredoxin glutathione reductase	3	0	0	3
apical membrane antigen 1, AMA1	2	0	0	2
hypothetical protein, conserved	1	0	0	1
luciferase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
pyruvate kinase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
intestinal alkaline phosphatase precursor	0	0	1	1
DNA polymerase beta	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Vif	0	1	0	1
Tat	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Pyruvate kinase PKM	0	1	0	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Inositol monophosphatase 1	2	0	0	2
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 12	0	2	0	2
Carbonic anhydrase 3	0	2	0	2
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 6	0	2	0	2
Delta-type opioid receptor	0	2	0	3
Delta-type opioid receptor	0	3	1	5
Mu-type opioid receptor	0	3	1	7
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Carbonic anhydrase 7	0	2	0	2
Guanine nucleotide-binding protein G	1	0	0	1
Mu-type opioid receptor	0	3	0	3
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
Carbonic anhydrase 14	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
histone deacetylase 9 isoform 3	1	0	0	1
GALC protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 2C19	0	1	0	1
muscarinic acetylcholine receptor M1	2	0	0	2
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cationic amino acid transporter 3	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucocorticoid receptor	0	6	0	6
Glycine receptor subunit alpha-1	0	6	0	6
Androgen receptor	0	2	0	2
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	1	1	2
Muscarinic acetylcholine receptor M2	0	1	0	1
Translocator protein	0	0	1	1
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Kappa-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Bile salt export pump	0	1	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Alpha-1B adrenergic receptor	0	2	0	2
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Smad3	1	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (115)

Protein Targets (643)

Seroma

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (115)

Drugs Studied (72)

Protein Targets (643)