Hydroa Vacciniforme

A vesicular and bullous eruption having a tendency to recur in summer during childhood and commonly appearing on sun-exposed skin. The lesions are surrounded by an erythematous zone and resemble a vaccination. (From Dorland, 27th ed)

Synonym
Hydroa Vacciniforme

Excerpt	Reference
"Hydroa vacciniforme is a rare, chronic photodermatosis with onset in childhood."	( Goldgeier, MH; Lucky, AW; McCarthy, MJ; McGuire, J; Nordlund, JJ; Sibrack, LA, 1982)
"Hydroa vacciniforme is a very rare photodermatosis, commencing in childhood and belonging to the category of idiopathic burns."	( André, J; Bruderer, P; Christoffersen, S; Ledoux, M; Shahabpour, M, 1995)
"Hydroa vacciniforme is a troublesome and scarring photosensitivity disorder for which treatment is unsatisfactory."	( Rhodes, LE; White, SI, 1998)
"Hydroa vacciniforme is an exceptional photodermatosis of uncertain etiology."	( Balguerie, X; Cordel, N; Joly, P; Lauret, P; Leroy, D; Modeste, AB, 2001)
"Hydroa vacciniforme is a rare, usually quite severe, photo-dermatosis."	( Andersson, J; Carlsson, G; Linde, A; Lysell, J; Malmros-Svennilson, J; Wahlgren, CF; Westermark, A; Wiegleb Edström, D, 2009)
"Hydroa vacciniforme is one of the rarest forms of photosensitivity disorders of the skin."	( Bygum, A; Clemmensen, O; Fisker, N; Pahlow Mose, A, 2014)

Excerpt	Reference
"Lately, hydroa vacciniforme has been associated with Epstein-Barr virus infection."	( Bygum, A; Clemmensen, O; Fisker, N; Pahlow Mose, A, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	13 (31.71)	23.3326
1990's	7 (17.07)	12.5806
2000's	9 (21.95)	18.1394
2010's	11 (26.83)	28.8240
2020's	1 (2.44)	9.53

Drug	Relationship Strength	Studies	Trials
kynurenine	low	1	0
niacin	low	2	0
4-aminobenzoic acid	low	1	0
pyridoxine	low	1	0
amiodarone	medium	1	1
chloroquine	low	2	0
hydroxychloroquine	low	3	0
khellin	low	1	0
kynurenic acid	low	1	0
procarbazine	low	1	0
thalidomide	low	3	0
xanthurenic acid	low	1	0
prednisolone	low	2	0
prednisone	low	5	0
cloxacillin	low	1	0
desoxycorticosterone	low	1	0
histidine	low	2	0
valine	low	3	0
tryptophan	low	1	0
methylprednisolone	low	1	0
tacrolimus	low	1	0
eicosapentaenoic acid	medium	3	1
riboflavin	low	1	0
urocanic acid	low	1	0
fusidic acid	low	1	0
dinoprostone	medium	1	1
beta carotene	low	1	0
canthaxanthin	low	1	0
phenylephrine hydrochloride	low	1	0
minocycline	low	1	0
cyclosporine	low	1	0
promega	medium	3	1
acyclovir	low	4	0
ganciclovir	low	1	0
valacyclovir	low	3	0
eye	low	2	0

Protein Targets (544)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Genome polyprotein	0	0	1	1
USP1 protein, partial	8	0	0	8
AR protein	15	0	0	15
thyroid stimulating hormone receptor	5	0	0	5
glucocorticoid receptor [Homo sapiens]	11	0	0	11
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
estrogen nuclear receptor alpha	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	6	0	0	6
Histone H2A.x	3	0	0	3
chromobox protein homolog 1	7	0	0	7
transcriptional regulator ERG isoform 3	1	0	0	1
geminin	12	0	0	12
Polyphenol oxidase 2	0	2	0	2
Cellular tumor antigen p53	10	0	0	10
Thiopurine S-methyltransferase	0	1	0	1
Succinate-semialdehyde dehydrogenase, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Cytochrome P450 1B1	0	2	0	2
Dihydropteroate synthase	0	0	1	1
Chain A, Toluene-4-monooxygenase system protein A	0	1	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Ferritin light chain	3	0	0	3
Thymidine kinase	0	2	0	2
thioredoxin reductase	5	0	0	5
phosphopantetheinyl transferase	7	0	0	7
GLS protein	6	0	0	6
TDP1 protein	18	0	0	18
Smad3	1	0	0	1
EWS/FLI fusion protein	8	0	0	8
arylsulfatase A	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	13	0	0	13
activating transcription factor 6	4	0	0	4
Bloom syndrome protein isoform 1	6	0	0	6
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
lamin isoform A-delta10	8	0	0	8
Solute carrier family 22 member 1	0	0	0	3
ATP-binding cassette sub-family C member 3	0	8	0	8
Multidrug resistance-associated protein 4	0	8	0	9
Solute carrier family 22 member 6	0	0	0	1
Bile salt export pump	0	5	0	5
Bile salt export pump	0	14	0	14
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	5	1	6
Cytochrome P450 2J2	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	0	0	3
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	3
Canalicular multispecific organic anion transporter 1	0	8	0	8
Thymidine kinase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
acetylcholinesterase	4	0	0	4
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
RAR-related orphan receptor gamma	7	0	0	7
SMAD family member 2	4	0	0	4
ATAD5 protein, partial	2	0	0	2
Fumarate hydratase	2	0	0	2
NFKB1 protein, partial	2	0	0	2
PPM1D protein	3	0	0	3
SMAD family member 3	4	0	0	4
Thrombopoietin	1	0	0	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	13	0	0	13
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
estrogen receptor 2 (ER beta)	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
progesterone receptor	6	0	0	6
retinoid X nuclear receptor alpha	6	0	0	6
estrogen-related nuclear receptor alpha	11	0	0	11
farnesoid X nuclear receptor	4	0	0	4
pregnane X nuclear receptor	7	0	0	7
G	3	0	0	3
cytochrome P450 2D6	4	0	0	4
polyprotein	2	0	0	2
peroxisome proliferator-activated receptor delta	3	0	0	3
peroxisome proliferator activated receptor gamma	7	0	0	7
caspase-3	1	0	0	1
thyroid stimulating hormone receptor	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
cytochrome P450 2D6 isoform 1	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
D(1A) dopamine receptor	1	0	0	1
thyroid hormone receptor beta isoform a	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
thyroid hormone receptor beta isoform 2	8	0	0	8
heat shock protein beta-1	2	0	0	2
huntingtin isoform 2	1	0	0	1
mitogen-activated protein kinase 1	6	0	0	6
flap endonuclease 1	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	5	0	0	5
peripheral myelin protein 22	6	0	0	6
survival motor neuron protein isoform d	4	0	0	4
cytochrome P450 3A4 isoform 1	5	0	0	5
muscarinic acetylcholine receptor M1	2	0	0	2
lethal factor (plasmid)	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	5	0	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Lysine-specific demethylase PHF2	0	1	0	1
Interferon beta	6	0	0	6
HLA class I histocompatibility antigen, B alpha chain	3	0	0	3
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Integrin beta-3	1	0	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	5	0	5
Muscarinic acetylcholine receptor M4	0	4	0	4
ATP-dependent translocase ABCB1	0	2	1	3
Integrin alpha-IIb	1	0	0	1
Beta-1 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M5	0	4	0	4
Alpha-2A adrenergic receptor	0	4	0	4
Adenosine receptor A3	0	2	0	2
Cytochrome P450 2C8	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	0	4
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Androgen receptor	0	5	0	5
Gamma-aminobutyric acid receptor subunit beta-1	5	0	0	5
Alpha-1B adrenergic receptor	0	2	0	2
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	4	0	4
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	5	0	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-5	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	5	0	0	5
Muscarinic acetylcholine receptor M3	0	4	0	4
ATP-dependent translocase ABCB1	0	1	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	5	0	0	5
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Histamine H2 receptor	0	2	0	2
Endothelin-1 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	5	0	0	5
Gamma-aminobutyric acid receptor subunit gamma-3	5	0	0	5
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	5	0	0	5
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Histamine H2 receptor	1	0	0	1
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	4	1	2	7
Gamma-aminobutyric acid receptor subunit alpha-1	5	0	0	5
Gamma-aminobutyric acid receptor subunit beta-3	5	0	0	5
Gamma-aminobutyric acid receptor subunit beta-2	5	0	0	5
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Lysine-specific demethylase 7A	0	1	0	1
GABA theta subunit	5	0	0	5
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Inositol hexakisphosphate kinase 1	3	0	0	3
Sodium channel protein type 2 subunit alpha	0	1	0	1
Ataxin-2	5	0	0	5
Sigma non-opioid intracellular receptor 1	0	4	0	4
Gamma-aminobutyric acid receptor subunit epsilon	5	0	0	5
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
cytochrome P450 2C9, partial	3	0	0	3
ATP-dependent phosphofructokinase	5	0	0	5
core protein, partial	0	1	0	1
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	3	0	3
Chain A, Cruzipain	2	0	0	2
15-lipoxygenase, partial	3	0	0	3
Microtubule-associated protein tau	4	0	0	4
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	1	0	1
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	2	0	2
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	1	2	3
Cytochrome P450 3A4	0	3	1	4
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	2	2	4
Spike glycoprotein	0	1	0	1
Replicase polyprotein 1ab	0	2	2	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	2	0	2
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Beta-lactamase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	3	0	4
Beta-lactamase TEM	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Efflux transporter	0	1	0	1
Beta-lactamase	0	1	0	1
Solute carrier family 15 member 2	0	2	0	2
Metallo-b-lactamase	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
GALC protein	3	0	0	3
GLI family zinc finger 3	9	0	0	9
cytochrome P450 family 3 subfamily A polypeptide 4	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	3	0	0	3
IDH1	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
Solute carrier family 22 member 3	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	2	0	0	2
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Glutamate receptor 2	2	1	0	4
TAR DNA-binding protein 43	1	0	0	1
Solute carrier family 22 member 2	0	1	0	1
regulator of G-protein signaling 4	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
prostaglandin E2 receptor EP2 subtype	1	0	0	1
vitamin D3 receptor isoform VDRA	4	0	0	4
Solute carrier family 22 member 2	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
DNA polymerase kappa isoform 1	3	0	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Trypsin	0	1	0	1
Cytochrome P450 1A2	0	3	0	3
Coagulation factor VII	0	1	0	1
Aromatase	0	1	0	1
Tissue factor	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Oxoeicosanoid receptor 1	0	1	0	1
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
thioredoxin glutathione reductase	4	0	0	4
streptokinase A precursor	0	0	1	1
Albumin	0	0	2	2
Estrogen receptor	0	0	1	1
Guanine nucleotide-binding protein G	1	0	0	1
Estrogen receptor beta	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
large T antigen	0	1	0	1
endonuclease IV	1	0	0	1
ClpP	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Carbonic anhydrase 12	0	0	0	2
Carbonic anhydrase 1	0	0	0	3
Carbonic anhydrase 2	0	0	0	3
Plasma kallikrein	0	0	0	2
Carbonic anhydrase 3	0	0	0	2
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase 4	0	0	0	2
Carbonic anhydrase 6	0	0	0	2
Adenosine receptor A1	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	0	5
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 7	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2A	0	1	0	4
Glutamate receptor ionotropic, NMDA 2B	0	1	0	4
Glutamate receptor ionotropic, NMDA 2C	0	1	0	4
Large neutral amino acids transporter small subunit 1	0	3	0	3
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	4
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	4
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 15	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	4
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	0	0	2
Genome polyprotein	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
glp-1 receptor, partial	3	0	0	3
aryl hydrocarbon receptor	4	0	0	4
cytochrome P450 2C19 precursor	3	0	0	3
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 2D6	0	1	0	1
Cytochrome P450 2C19	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
alpha-galactosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Mitogen-activated protein kinase 13	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Glutamate receptor 1	0	1	0	2
Glutamate receptor 3	0	1	0	2
Glutamate receptor 4	0	1	0	2
Glutamate receptor ionotropic, kainate 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Aryl hydrocarbon receptor	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	0	2
Glutamate receptor ionotropic, kainate 3	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	1	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Mitogen-activated protein kinase 11	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
Glutamate receptor ionotropic, kainate 5	0	1	0	2
Vesicular glutamate transporter 3	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
G-protein coupled receptor 35	0	2	1	3
Histamine H3 receptor	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
nonstructural protein 1	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
ATPase family AAA domain-containing protein 5	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
thyrotropin-releasing hormone receptor	2	0	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Cholesteryl ester transfer protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
Multidrug and toxin extrusion protein 1	0	1	0	1
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Macrophage migration inhibitory factor	0	1	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
pregnane X receptor	1	0	0	1
Nuclear receptor ROR-gamma	1	0	0	1
Pyridoxal kinase	0	0	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
tumor necrosis factor	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Caspase-7	1	0	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Inositol monophosphatase 1	1	0	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Cereblon isoform 4	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
peripheral myelin protein 22 isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
Dihydrofolate reductase	0	2	0	2
Myeloperoxidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
neuropeptide S receptor isoform A	1	0	0	1
Chain A, Beta-lactamase	1	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (41)

Protein Targets (544)

Hydroa Vacciniforme

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (41)

Drugs Studied (47)

Protein Targets (544)