Exanthema Subitum

An acute, short-lived, viral disease of infants and young children characterized by a high fever at onset that drops to normal after 3-4 days and the concomitant appearance of a macular or maculopapular rash that appears first on the trunk and then spreads to other areas. It is the sixth of the classical exanthematous diseases and is caused by HHV-6; (HERPESVIRUS 6, HUMAN). (From Dorland, 27th ed)

Synonyms(3)

Synonym
Exanthema Subitum
Sixth Disease
Roseola Infantum

Research

Studies (34)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	9 (26.47)	23.3326
1990's	8 (23.53)	12.5806
2000's	10 (29.41)	18.1394
2010's	7 (20.59)	28.8240
2020's	0 (0.00)	9.53

Drug	Relationship Strength	Studies
mercaptoethanol	low	1
phenytoin	low	3
aspirin	low	2
carbamazepine	low	2
valproic acid	low	1
foscarnet	low	2
phenobarbital	low	4
propranolol	low	1
sulfasalazine	low	4
prednisolone	low	2
prednisone	low	1
cycloheximide	low	1
cytarabine	low	1
acridines	low	1
pyrazines	low	1
idarubicin	low	1
metaperiodate	low	1
bortezomib	low	1
dactinomycin	low	1
melphalan	low	1
zinc oxide	low	1
technetium tc 99m exametazime	low	1
cyclosporine	low	2
exudates	low	2
acyclovir	low	1
ganciclovir	low	3
allopurinol	low	2

Protein Targets (591)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Ferritin light chain	4	0	0	4
thioredoxin reductase	10	0	0	10
TDP1 protein	16	0	0	16
Microtubule-associated protein tau	6	0	0	6
Smad3	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	11	0	0	11
alpha-galactosidase	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
flap endonuclease 1	5	0	0	5
DNA polymerase iota isoform a (long)	5	0	0	5
DNA topoisomerase 2-alpha	0	0	0	1
Acetylcholinesterase	0	1	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Thymidine kinase	0	2	0	2
phosphopantetheinyl transferase	3	0	0	3
GLS protein	6	0	0	6
thyroid stimulating hormone receptor	5	0	0	5
EWS/FLI fusion protein	7	0	0	7
arylsulfatase A	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	14	0	0	14
activating transcription factor 6	3	0	0	3
Histone H2A.x	7	0	0	7
Bloom syndrome protein isoform 1	7	0	0	7
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
lamin isoform A-delta10	10	0	0	10
Solute carrier family 22 member 1	0	1	0	3
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	12
Solute carrier family 22 member 6	0	1	0	2
Bile salt export pump	0	4	0	4
Bile salt export pump	0	15	0	15
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	6	0	6
Cytochrome P450 2J2	0	5	0	5
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	0	0	2
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	11	0	11
Thymidine kinase	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	11	0	0	11
AR protein	15	0	0	15
nuclear receptor subfamily 1, group I, member 3	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	7	0	0	7
glucocorticoid receptor [Homo sapiens]	11	0	0	11
estrogen-related nuclear receptor alpha	15	0	0	15
pregnane X nuclear receptor	8	0	0	8
estrogen nuclear receptor alpha	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
heat shock protein beta-1	2	0	0	2
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	9	0	0	9
Xanthine dehydrogenase/oxidase	0	3	0	3
TAR DNA-binding protein 43	4	0	0	4
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	10	0	0	10
interleukin 8	4	0	0	4
estrogen receptor 2 (ER beta)	6	0	0	6
progesterone receptor	7	0	0	7
IDH1	6	0	0	6
transcriptional regulator ERG isoform 3	2	0	0	2
thyroid hormone receptor beta isoform 2	7	0	0	7
ras-related protein Rab-9A	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
geminin	11	0	0	11
survival motor neuron protein isoform d	6	0	0	6
Polyphenol oxidase 2	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Cellular tumor antigen p53	10	0	0	10
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	1	2	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
Carbonic anhydrase 1	0	6	0	10
Carbonic anhydrase 2	0	7	0	10
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Amino acid transporter	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
cytochrome P450 2D6	3	0	0	3
glucocerebrosidase	2	0	0	2
peroxisome proliferator-activated receptor delta	5	0	0	5
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
DNA polymerase kappa isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	3	0	0	3
lethal factor (plasmid)	2	0	0	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	0	1	0	1
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	6	0	0	6
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	6	3	1	10
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
Fumarate hydratase	4	0	0	4
PPM1D protein	3	0	0	3
caspase 7, apoptosis-related cysteine protease	3	0	0	3
retinoid X nuclear receptor alpha	5	0	0	5
farnesoid X nuclear receptor	6	0	0	6
polyprotein	4	0	0	4
peroxisome proliferator activated receptor gamma	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
caspase-3	3	0	0	3
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Histone deacetylase 3	0	3	0	3
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	1	0	2
Prothrombin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Interferon beta	9	0	0	9
Carbonic anhydrase 3	0	1	0	2
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	3	0	4
Carbonic anhydrase 6	0	1	0	2
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
Carbonic anhydrase 5A, mitochondrial	0	3	0	4
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	1	0	2
26S proteasome regulatory subunit 6B	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	3	0	3
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	3	0	4
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Histone deacetylase 2	0	3	0	3
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	2
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Carbonic anhydrase 14	0	1	0	2
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
Chain A, Beta-lactamase	2	0	0	2
acetylcholinesterase	2	0	0	2
USP1 protein, partial	7	0	0	7
thyroid hormone receptor beta isoform a	7	0	0	7
mitogen-activated protein kinase 1	3	0	0	3
Vpr	1	0	0	1
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	3
Cytochrome P450 2B6	0	0	1	1
Sodium channel protein type 4 subunit alpha	0	3	0	5
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Sodium channel protein type 9 subunit alpha	0	4	0	4
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
glp-1 receptor, partial	3	0	0	3
pregnane X receptor	3	0	0	3
ATAD5 protein, partial	4	0	0	4
GLI family zinc finger 3	7	0	0	7
67.9K protein	2	0	0	2
P53	1	0	0	1
RPL19A	0	0	1	1
aryl hydrocarbon receptor	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	2	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
chromobox protein homolog 1	6	0	0	6
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	5	0	0	5
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
cytochrome P450 3A4 isoform 1	6	0	0	6
COUP transcription factor 2 isoform a	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	6	2	1	9
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	6	2	1	9
Gamma-aminobutyric acid receptor subunit delta	6	2	1	9
Gamma-aminobutyric acid receptor subunit gamma-2	6	2	1	9
Gamma-aminobutyric acid receptor subunit alpha-5	6	2	1	9
Gamma-aminobutyric acid receptor subunit alpha-3	6	2	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	6	2	1	9
Gamma-aminobutyric acid receptor subunit alpha-2	6	2	1	9
Gamma-aminobutyric acid receptor subunit alpha-4	6	2	1	9
Gamma-aminobutyric acid receptor subunit gamma-3	6	2	1	9
Gamma-aminobutyric acid receptor subunit alpha-6	6	2	1	9
Alpha-synuclein	1	0	0	1
Spike glycoprotein	2	0	1	3
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	6	2	1	9
Gamma-aminobutyric acid receptor subunit beta-2	6	2	1	9
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
GABA theta subunit	6	2	1	9
Endothelial PAS domain-containing protein 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	6	2	1	9
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	1
endonuclease IV	4	0	0	4
G	4	0	0	4
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
peripheral myelin protein 22	4	0	0	4
nuclear receptor coactivator 3 isoform a	0	1	0	1
Thymidine kinase 2, mitochondrial	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	0	0	1
Cytochrome P450 3A4	0	2	0	2
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	2	0	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Inositol hexakisphosphate kinase 1	4	0	0	4
Deoxynucleoside kinase	0	1	0	1
cytochrome P450 2C9, partial	4	0	0	4
ATP-dependent phosphofructokinase	2	0	0	2
Deoxycytidine kinase	0	0	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, Cruzipain	1	0	0	1
15-lipoxygenase, partial	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
RAD51	0	1	0	1
vitamin D3 receptor isoform VDRA	3	0	0	3
huntingtin isoform 2	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
caspase-1 isoform alpha precursor	1	0	0	1
ATP-dependent translocase ABCB1	0	2	1	4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	1	0	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	2	1	3
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
DNA polymerase delta catalytic subunit	0	1	0	1
ClpP	1	0	0	1
NFKB1 protein, partial	1	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
Plasma kallikrein	0	0	0	1
Histidine-binding periplasmic protein	0	0	1	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
DNA polymerase III, partial	1	0	0	1
regulator of G-protein signaling 4	2	0	0	2
nonstructural protein 1	1	0	0	1
NPYLR7B	0	0	1	1
Parkin	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
D(1A) dopamine receptor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
glucokinase regulatory protein	1	0	0	1
DNA polymerase beta	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Amyloid-beta precursor protein	1	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Inositol monophosphatase 1	2	0	0	2
Single-stranded DNA cytosine deaminase	1	0	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
thioredoxin glutathione reductase	2	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Gamma-aminobutyric acid	0	1	0	1
cytochrome P450 2C9 precursor	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
5-hydroxytryptamine receptor 1A	0	3	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Histamine H2 receptor	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	4	2	11
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	3	0	3
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Beta-1 adrenergic receptor	0	1	1	3
5-hydroxytryptamine receptor 4	0	2	0	2
Albumin	0	0	1	1
Cytochrome P450 1A2	0	1	0	1
Beta-2 adrenergic receptor	0	2	1	3
Muscarinic acetylcholine receptor M2	0	1	1	2
Beta-1 adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-2A adrenergic receptor	0	1	2	4
Adenosine receptor A3	0	1	1	2
Beta-2 adrenergic receptor	0	2	0	3
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2D6	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	1	2
Beta-3 adrenergic receptor	0	2	1	3
D(2) dopamine receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
Alpha-2B adrenergic receptor	0	0	1	2
Beta-1 adrenergic receptor	0	2	1	4
Alpha-2C adrenergic receptor	0	1	2	4
D(3) dopamine receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	1	1
Muscarinic acetylcholine receptor M3	0	1	1	2
D(1A) dopamine receptor	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Alpha-1D adrenergic receptor	0	1	1	2
Alpha-1D adrenergic receptor	0	0	1	2
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	2	1	3
5-hydroxytryptamine receptor 2C	0	2	1	3
5-hydroxytryptamine receptor 1B	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	1	2
Cytochrome P450 2C19	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	4
Alpha-1B adrenergic receptor	0	0	1	2
Mu-type opioid receptor	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Delta-type opioid receptor	0	1	1	2
Kappa-type opioid receptor	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	1	3
Alpha-1A adrenergic receptor	0	1	1	2
5-hydroxytryptamine receptor 6	0	2	1	3
5-hydroxytryptamine receptor 7	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Beta-2 adrenergic receptor	0	1	1	3
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, Glutathione S-transferase	0	1	0	1
Luciferase	2	0	0	2
thyroid stimulating hormone receptor	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Tumor necrosis factor	0	0	1	1
Interstitial collagenase	0	1	0	1
Fibroblast growth factor 1	0	0	1	1
Thromboxane-A synthase	0	1	0	1
Mitogen-activated protein kinase 1	0	1	0	1
Caspase-1	0	1	0	1
Flavin reductase (NADPH)	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Histone deacetylase 7	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Exanthema Subitum

Synonyms(3)

Research

Studies (34)

Drugs Studied (33)

Protein Targets (591)