Page last updated: 2024-12-09

Methyl Haematommate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID591773
CHEMBL ID470649
CHEBI ID144173

Synonyms (19)

Synonym
methyl haematomate
smr000470887
MLS000697753
methyl haematommate
bdbm50241521
methyl 3-formyl-2,4-dihydroxy-6-methylbenzoate
methyl beta-orcinol carboxylate
CHEMBL470649 ,
CHEBI:144173
34874-90-3
benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, methyl ester
methyl 2,4-dihydroxy-3-formyl-6-methylbenzoate
methyl hematommate
PXFMUVDLJWXOQM-UHFFFAOYSA-N
methyl 3-formyl-2,4-dihydroxy-6-methylbenzoate #
DTXSID60343723
methyl 3-formyl-2,4-dihydroxy-6-methyl-benzoate
Q63398814
2,4-dihydroxy-3-formyl-6-methylbenzoic acid methyl ester
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
4-hydroxybenzoate esterA benzoate ester that is an ester of 4-hydroxybenzoic acid.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (7)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
TDP1 proteinHomo sapiens (human)Potency5.17350.000811.382244.6684AID686979
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency3.16230.707912.194339.8107AID720542
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency50.11873.548119.542744.6684AID743266
flap endonuclease 1Homo sapiens (human)Potency22.38720.133725.412989.1251AID588795
gemininHomo sapiens (human)Potency0.65130.004611.374133.4983AID624296
VprHuman immunodeficiency virus 1Potency31.62281.584919.626463.0957AID651644
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)IC50 (µMol)200.00000.00053.49849.7600AID424242
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (27)

Processvia Protein(s)Taxonomy
positive regulation of JUN kinase activityTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
protein dephosphorylationTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
insulin receptor signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
regulation of signal transductionTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of signal transductionTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
actin cytoskeleton organizationTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
regulation of endocytosisTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of vascular endothelial growth factor receptor signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
endoplasmic reticulum unfolded protein responseTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
regulation of intracellular protein transportTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
cellular response to unfolded proteinTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
peptidyl-tyrosine dephosphorylationTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
IRE1-mediated unfolded protein responseTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
insulin receptor recyclingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of MAP kinase activityTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of insulin receptor signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
regulation of type I interferon-mediated signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STATTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
positive regulation of protein tyrosine kinase activityTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascadeTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
regulation of hepatocyte growth factor receptor signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathwayTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
positive regulation of IRE1-mediated unfolded protein responseTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
negative regulation of PERK-mediated unfolded protein responseTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activityTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
positive regulation of receptor catabolic processTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (12)

Processvia Protein(s)Taxonomy
RNA bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
protein tyrosine phosphatase activityTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
insulin receptor bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
protein bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
zinc ion bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
enzyme bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
protein kinase bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
receptor tyrosine kinase bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
cadherin bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
ephrin receptor bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
protein phosphatase 2A bindingTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
non-membrane spanning protein tyrosine phosphatase activityTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (11)

Processvia Protein(s)Taxonomy
plasma membraneTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
cytoplasmTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
mitochondrial matrixTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
early endosomeTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
endoplasmic reticulumTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
cytosolTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
mitochondrial cristaTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
endosome lumenTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
sorting endosomeTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
cytoplasmic side of endoplasmic reticulum membraneTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
protein-containing complexTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
endoplasmic reticulumTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
cytoplasmTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
early endosomeTyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (63)

Assay IDTitleYearJournalArticle
AID1419091Antiinflammatory activity in PMA-differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha secretion at 20 uM preincubated for 2 hrs followed by LPS stimulation and measured after 24 hrs post LPS challenge by ELISA relative to control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1081971Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081968Antifungal activity against Fusarium udum assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081982Antifungal activity against Athelia rolfsii assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081966Antifungal activity against Pythium aphanidermatum assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081962Antifungal activity against Pythium debaryanum assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID424242Inhibition of PTP1B2009Bioorganic & medicinal chemistry letters, May-15, Volume: 19, Issue:10
Protein tyrosine phosphatase 1B inhibitory effects of depsidone and pseudodepsidone metabolites from the Antarctic lichen Stereocaulon alpinum.
AID1081959Antifungal activity against Pythium debaryanum assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081978Antifungal activity against Rhizoctonia solani assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081975Antifungal activity against Rhizoctonia solani assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1419085Inhibition of TLR4 in human U937-3xkappaB-LUC cells assessed as inhibition of Aggregatibacter actinomycetemcomitans LPS-induced NF-kappaB activation at 20 uM preincubated for 30 mins followed by LPS stimulation and measured after 6 hrs post LPS challenge 2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1081967Antifungal activity against Fusarium udum assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1419084Inhibition of TLR4 in human U937-3xkappaB-LUC cells assessed as inhibition of Aggregatibacter actinomycetemcomitans LPS-induced NF-kappaB activation at 50 uM preincubated for 30 mins followed by LPS stimulation and measured after 6 hrs post LPS challenge 2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1437929Antibacterial activity against Streptococcus mutans ATCC 25175 after 24 hrs2017Journal of natural products, 01-27, Volume: 80, Issue:1
Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.
AID1081964Antifungal activity against Pythium aphanidermatum assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID377856Phytogrowth-inhibitory activity against Echinochloa crusgalli assessed as inhibition of seedling growth2000Journal of natural products, Oct, Volume: 63, Issue:10
Effect of lichen metabolites on thylakoid electron transport and photophosphorylation in isolated spinach chloroplasts.
AID1081974Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1419082Cytotoxicity against PMA-differentiated human U937 macrophages assessed as cell viability at 20 uM after 24 hrs by MTT assay relative to untreated control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID377853Phytogrowth-inhibitory activity against Amaranthus hypochondriacus assessed as inhibition of seedling growth2000Journal of natural products, Oct, Volume: 63, Issue:10
Effect of lichen metabolites on thylakoid electron transport and photophosphorylation in isolated spinach chloroplasts.
AID1081961Antifungal activity against Pythium debaryanum assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081972Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081969Antifungal activity against Fusarium udum assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1419080Cytotoxicity against PMA-differentiated human U937 macrophages assessed as cell viability at 80 uM after 24 hrs by MTT assay relative to untreated control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1419087Inhibition of TLR4 in human U937-3xkappaB-LUC cells assessed as inhibition of Aggregatibacter actinomycetemcomitans LPS-induced NF-kappaB activation at 5 uM preincubated for 30 mins followed by LPS stimulation and measured after 6 hrs post LPS challenge b2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1437931Bactericidal activity against Streptococcus mutans ATCC 25175 after 24 hrs2017Journal of natural products, 01-27, Volume: 80, Issue:1
Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.
AID1081980Antifungal activity against Athelia rolfsii assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081981Antifungal activity against Athelia rolfsii assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1419081Cytotoxicity against PMA-differentiated human U937 macrophages assessed as cell viability at 40 uM after 24 hrs by MTT assay relative to untreated control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1081963Antifungal activity against Pythium aphanidermatum assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1437930Bactericidal activity against Porphyromonas gingivalis ATCC 33277 after 24 hrs2017Journal of natural products, 01-27, Volume: 80, Issue:1
Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.
AID1081965Antifungal activity against Pythium aphanidermatum assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID468209Cytotoxicity against human HaCaT cells after 72 hrs by MTT assay2009Journal of natural products, Dec, Volume: 72, Issue:12
Cytotoxic constituents of the lichen Diploicia canescens.
AID377854Phytogrowth-inhibitory activity against Echinochloa crusgalli assessed as inhibition of seedling germination2000Journal of natural products, Oct, Volume: 63, Issue:10
Effect of lichen metabolites on thylakoid electron transport and photophosphorylation in isolated spinach chloroplasts.
AID1419099Antiinflammatory activity in human U937 cells assessed as inhibition of LPS-induced IL-8 production preincubated for 2 hrs followed by LPS stimulation and measured after 24 hrs post LPS challenge by ELISA2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1419092Antiinflammatory activity in PMA-differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha secretion at 10 uM preincubated for 2 hrs followed by LPS stimulation and measured after 24 hrs post LPS challenge by ELISA relative to control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1419090Antiinflammatory activity in PMA-differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha secretion at 40 uM preincubated for 2 hrs followed by LPS stimulation and measured after 24 hrs post LPS challenge by ELISA relative to control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1081979Antifungal activity against Athelia rolfsii assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081976Antifungal activity against Rhizoctonia solani assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1419086Inhibition of TLR4 in human U937-3xkappaB-LUC cells assessed as inhibition of Aggregatibacter actinomycetemcomitans LPS-induced NF-kappaB activation at 10 uM preincubated for 30 mins followed by LPS stimulation and measured after 6 hrs post LPS challenge 2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID468207Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay2009Journal of natural products, Dec, Volume: 72, Issue:12
Cytotoxic constituents of the lichen Diploicia canescens.
AID1081973Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1437932Antifungal activity against Candida albicans ATCC 28366 assessed as growth inhibition at 80 uM after 24 hrs2017Journal of natural products, 01-27, Volume: 80, Issue:1
Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.
AID1437928Antibacterial activity against Porphyromonas gingivalis ATCC 33277 after 24 hrs2017Journal of natural products, 01-27, Volume: 80, Issue:1
Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.
AID1419083Cytotoxicity against PMA-differentiated human U937 macrophages assessed as cell viability at 10 uM after 24 hrs by MTT assay relative to untreated control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID377855Phytogrowth-inhibitory activity against Amaranthus hypochondriacus assessed as inhibition of seedling germination2000Journal of natural products, Oct, Volume: 63, Issue:10
Effect of lichen metabolites on thylakoid electron transport and photophosphorylation in isolated spinach chloroplasts.
AID1419089Antiinflammatory activity in PMA-differentiated human U937 cells assessed as inhibition of LPS-induced TNFalpha secretion at 80 uM preincubated for 2 hrs followed by LPS stimulation and measured after 24 hrs post LPS challenge by ELISA relative to control2018Bioorganic & medicinal chemistry, 12-01, Volume: 26, Issue:22
Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ.
AID1081977Antifungal activity against Rhizoctonia solani assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081970Antifungal activity against Fusarium udum assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081960Antifungal activity against Pythium debaryanum assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.99 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]