Compounds > salazinic acid
Page last updated: 2024-08-01 16:16:22

salazinic acid

Description

salazinic acid: lichen metabolite; structure in first source [MeSH]

Cross-References

ID SourceID
PubMed CID5320418
CHEMBL ID172439
SCHEMBL ID3801772
MeSH IDM0299874

Synonyms (30)

Synonym
NCI60_041934
salazic acid
salazinic acid
521-39-1
NSC87509 ,
trihydroxy-(hydroxymethyl)-methyl-dioxo-[?]carbaldehyde
7h-isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde,1,3-dihydro-1,4,10-trihydroxy-5-(hydroxymethyl)-8-methyl-3,7-dioxo-
nsc-87509
smr000386938
MLS001049106
CHEMBL172439 ,
NCGC00241204-01
nsc 87509
1,3-dihydro-1,4,10-trihydroxy-5-(hydroxymethyl)-8-methyl-3,7-dioxo-7h-isobenzofuro(4,5-b)(1,4)benzodioxepin-11-carbaldehyde
einecs 208-312-0
SCHEMBL3801772
1,4,10-trihydroxy-5-hydroxymethyl-8-methyl-3,7-dioxo-1,3-dihydro-7h-benzo[e]furo[3'''''''',4'''''''':3,4]benzo[b][1,4]dioxepine-11-carbaldehyde
cid_5320418
bdbm29673
salazinic acid, 2
AKOS030493208
Q3604555
1,4,10-trihydroxy-5-(hydroxymethyl)-8-methyl-3,7-dioxo-1,3-dihydro-7h-benzo[6,7][1,4]dioxepino[2,3-e]isobenzofuran-11-carbaldehyde
1,3-dihydro-1,4,10-trihydroxy-5-(hydroxymethyl)-8-methyl-3,7-dioxo-7h-isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde
1,4,10-trihydroxy-5-(hydroxymethyl)-8-methyl-3,7-dioxo-1,3-dihydro-7h-2,6,12-trioxabenzo[5,6]cyclohepta[1,2-e]indene-11-carbaldehyde
STL564799
5,13,17-trihydroxy-12-(hydroxymethyl)-7-methyl-9,15-dioxo-2,10,16-trioxatetracyclo[9.7.0.03,8.014,18]octadeca-1(11),3(8),4,6,12,14(18)-hexaene-4-carbaldehyde
salacinic acid
DTXSID001317270
salacinicacid

Protein Targets (48)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency1.2589AID2517
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency4.8022AID485290; AID489007
Chain A, Beta-lactamaseEscherichia coli K-12Potency50.1187AID485294
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency17.7407AID2451
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency3.1623AID504339
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency19.9526AID2147
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency3.9811AID2549
Chain A, Ferritin light chainEquus caballus (horse)Potency31.6228AID485281
LuciferasePhotinus pyralis (common eastern firefly)Potency37.9330AID588342
thioredoxin reductaseRattus norvegicus (Norway rat)Potency50.1187AID588453
WRNHomo sapiens (human)Potency3.5481AID651768
phosphopantetheinyl transferaseBacillus subtilisPotency14.1254AID1490
USP1 protein, partialHomo sapiens (human)Potency50.1187AID743255
Microtubule-associated protein tauHomo sapiens (human)Potency19.1180AID1460; AID1468
thioredoxin glutathione reductaseSchistosoma mansoniPotency14.1254AID485364
Smad3Homo sapiens (human)Potency14.1254AID588855
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency1.1220AID720542
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency14.1254AID1030
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency19.9526AID504333
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency3.5481AID504332
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency35.4813AID2100
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency17.7828AID504847
chromobox protein homolog 1Homo sapiens (human)Potency7.0795AID540317
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency25.5154AID1469; AID1479
importin subunit beta-1 isoform 1Homo sapiens (human)Potency112.2020AID540263
DNA polymerase betaHomo sapiens (human)Potency2.2387AID485314
flap endonuclease 1Homo sapiens (human)Potency3.5481AID588795
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency25.1189AID463254
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency7.5193AID720504
snurportin-1Homo sapiens (human)Potency112.2020AID540263
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency70.7946AID2662
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency3.1623AID504891
DNA polymerase eta isoform 1Homo sapiens (human)Potency2.8184AID588591
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency1.1220AID588590
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency2.8184AID485360
gemininHomo sapiens (human)Potency0.1158AID624297
DNA polymerase kappa isoform 1Homo sapiens (human)Potency0.7943AID588579
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency50.1187AID2675
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency15.8489AID504327
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency31.6228AID720709
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency15.8489AID602233
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency23.9341AID485367

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)
RAD51Homo sapiens (human)IC5046.5085AID1435; AID1436
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)IC5014.8000AID2073
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)IC5014.8000AID2073
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)IC5042.0000AID1799757
Integrase Human immunodeficiency virus 1IC5013.4500AID93700; AID93702; AID93705; AID93707
large T antigenBetapolyomavirus macacaeIC5017.4900AID1903

Bioassays (38)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13ISSN: 1934-9300Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
ISSN: 1552-4922		Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
ISSN: 1557-8127		High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression2022The Journal of biological chemistry, 08, Volume: 298, Issue:8
ISSN: 1083-351X
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
ISSN: 1945-7170		A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID1799757Fluorescence Polarization (FP) Assay from Article 10.1016/j.chembiol.2012.05.013: \\Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening.\\2012Chemistry & biology, Jul-27, Volume: 19, Issue:7
ISSN: 1879-1301		Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening.
AID1081968Antifungal activity against Fusarium udum assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081970Antifungal activity against Fusarium udum assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081980Antifungal activity against Athelia rolfsii assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081978Antifungal activity against Rhizoctonia solani assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081977Antifungal activity against Rhizoctonia solani assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081961Antifungal activity against Pythium debaryanum assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081969Antifungal activity against Fusarium udum assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081963Antifungal activity against Pythium aphanidermatum assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081975Antifungal activity against Rhizoctonia solani assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID93702Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 21997Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
ISSN: 0022-2623		Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
AID1081982Antifungal activity against Athelia rolfsii assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081974Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081976Antifungal activity against Rhizoctonia solani assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID91562Percentage inhibition against strand transfer of HIV-1 integrase at 100 ug/mL1997Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
ISSN: 0022-2623		Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
AID1081966Antifungal activity against Pythium aphanidermatum assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081965Antifungal activity against Pythium aphanidermatum assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081962Antifungal activity against Pythium debaryanum assessed as growth inhibition at 250 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID93700Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 11997Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
ISSN: 0022-2623		Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
AID93705Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 11997Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
ISSN: 0022-2623		Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
AID1081959Antifungal activity against Pythium debaryanum assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081960Antifungal activity against Pythium debaryanum assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID93707Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 21997Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
ISSN: 0022-2623		Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
AID1081981Antifungal activity against Athelia rolfsii assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081971Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081967Antifungal activity against Fusarium udum assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081964Antifungal activity against Pythium aphanidermatum assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081973Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition at 125 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID1081979Antifungal activity against Athelia rolfsii assessed as growth inhibition by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.
AID91561Percentage inhibition of compound against 3'-processing of HIV-1 integrase at 100 ug/mL1997Journal of medicinal chemistry, Mar-14, Volume: 40, Issue:6
ISSN: 0022-2623		Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
AID1081972Antifungal activity against Rhizoctonia bataticola assessed as growth inhibition at 62.5 ug/ml by poisoned food technique2011Journal of agricultural and food chemistry, Mar-23, Volume: 59, Issue:6
ISSN: 1520-5118		Isolation, characterization and antifungal activity of major constituents of the Himalayan lichen Parmelia reticulata Tayl.

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (10.00)18.2507
2000's2 (10.00)29.6817
2010's11 (55.00)24.3611
2020's5 (25.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (4.55%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other21 (95.45%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
digallic acid
1
benzoate ester;
gallate ester		1997199727.0low001000
3,4-dihydroxybenzohydroxamic acid
1
benzoic acids1997199727.0low001000
psoromic acid
2
carbonyl compound1997201219.5medium001010
1,4,5,8-naphthalenetetracarboxylic acid
1
1997199727.0medium001000
physodic acid
2
carbonyl compound1997201219.5medium001010
hexaconazole
1
dichlorobenzene;
tertiary alcohol;
triazoles		chelator2011201113.0low000010
5,5'-methylenedisalicylic acid
1
1997199727.0low001000
atranorin
2
carbonyl compound1997201120.0low001010
methyl fluorone black
1
1997199727.0low001000
stictic acid
2
aromatic ether1997201219.5medium001010
2,4-dihydroxy-6-methylbenzoic acid ethyl ester
1
4-hydroxybenzoate ester2011201113.0medium000010
methyl 2,4-dihydroxy-3,6-dimethyl benzoate
1
4-hydroxybenzoate ester2011201113.0low000010
diffractaic acid
1
carbonyl compound1997199727.0low001000
3,4,5-trihydroxybenzohydroxamic acid
1
1997199727.0medium001000
pannarin
1
aldehyde;
aromatic ether;
depsidones;
organic heterotricyclic compound;
organochlorine compound;
phenols		antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
lichen metabolite		1997199727.0medium001000
(+)-usnic acid
1
usnic acid1997199727.0low001000
Methyl Haematommate
1
4-hydroxybenzoate ester2011201113.0medium000010
chlorogenic acid
1
cinnamate ester;
tannin		food component;
plant metabolite		1997199727.0low001000
fumarprotocetraric acid
1
carbonyl compound1997199727.0medium001000
baeomycesic acid
1
carbonyl compound2011201113.0medium000010
lichexanthone
1
aromatic ether;
phenols;
xanthones		plant metabolite2011201113.0medium000010
4,5-di-O-caffeoylquinic acid
1
quinic acid1997199727.0low001000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
fluorouracil
2
nucleobase analogue;
organofluorine compound		antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic		202320231.0low000002
usnic acid
7
benzofurans1998201514.0medium001240
4-butyrolactone
2
butan-4-olidemetabolite;
neurotoxin		1998201517.5low001010
orcinol
1
5-alkylresorcinol;
dihydroxytoluene		Aspergillus metabolite2013201311.0low000010
evernic acid
3
carbonyl compound2009202010.0medium000120
protolichesterinic acid
2
1998201517.5medium001010
depsidone
1
depsidones;
organic heterotricyclic compound		202020204.0low000010
atranorin
2
carbonyl compound1998201617.0low001010
lobaric acid
2
carbonyl compound1998202015.0low001010
stictic acid
1
aromatic ether2010201014.0low000100
lecanoric acid
1
benzoate ester2013201311.0low000010
gyrophoric acid
2
carbonyl compound2009201313.0medium000110
benzofurans
7
1998201514.0low001240
fumarprotocetraric acid
1
carbonyl compound2013201311.0medium000010
norstictic acid
2
201520206.5medium000020
fumarates
1
butenedioate;
C4-dicarboxylate		human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite		2013201311.0low000010
protocetraric acid
1
carbonyl compound2012201212.0high000010
oxepins
1
2010201014.0low000100
salicylates
11
monohydroxybenzoateplant metabolite1998202310.5medium001271
vulpinic acid
1
butenolide2009200915.0low000100
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Benign Neoplasms0
1
2009200915.0medium000100
Fatty Liver0
1
202320231.0medium000001
Inflammation0
1
2010201014.0medium000100
Innate Inflammatory Response0
1
2010201014.0medium000100
Liver Steatosis0
1
202320231.0medium000001
Neoplasms0
1
2009200915.0medium000100
Sarcoma0
2
202320231.0medium000002
Sarcoma, Epithelioid0
2
202320231.0medium000002