Flexor Tendon Entrapment

A painful disability in the hand affecting the finger or thumb. It is caused by mechanical impingement of the digital flexor tendons as they pass through a narrowed retinacular pulley at the level of the metacarpal head. Thickening of the sheath and fibrocartilaginous metaplasia can occur, and nodules can form. (From Green's Operative Hand Surgery, 5th ed, p2137-58).

Synonym
Trigger Digits
Flexor Tendon Entrapment
Trigger Finger Disorder
Trigger Thumb
Snapping Finger

Excerpt	Reference
"Trigger thumb is a common hand disability in children and is primarily treated with open surgery."	( Liu, J; Liu, W; Tan, X; Wang, S, 2018)

Excerpt	Reference
"Surgical release of pediatric trigger thumbs has been recommended as definitive treatment, although controversy exists over the natural history of pediatric trigger thumb."	( Hutchinson, DT; Montanez, A; Rane, AA, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	3 (2.07)	23.3326
1990's	0 (0.00)	12.5806
2000's	17 (11.72)	18.1394
2010's	78 (53.79)	28.8240
2020's	47 (32.41)	9.53

Drug	Relationship Strength	Studies	Trials
acetaminophen	medium	3	2
anastrozole	low	1	0
bupivacaine	medium	2	1
celecoxib	low	1	0
diclofenac	low	2	0
ibuprofen	medium	2	2
lidocaine	medium	20	9
ketamine	low	1	0
ketorolac	low	2	0
khellin	low	1	0
letrozole	low	1	0
apnea	low	1	0
prilocaine	medium	2	2
sevoflurane	low	1	0
phentolamine	low	1	0
penicillamine	low	1	0
methylprednisolone acetate	medium	5	5
methicillin	low	1	0
methylene blue	low	1	0
valine	low	1	0
isoleucine	low	1	0
triamcinolone acetonide	medium	19	9
methylprednisolone	medium	9	7
betamethasone	medium	5	4
triamcinolone hexacetonide	medium	1	1
trolamine salicylate	low	9	0
triamcinolone	medium	13	4
remifentanil	low	1	0
betamethasone sodium phosphate	medium	1	1
fibrinogen	low	2	0
betamethasone acetate phosphate	medium	1	1
betamethasone-17,21-dipropionate	medium	1	1
ropivacaine	medium	3	1
cortisone	low	1	0
epinastine	low	1	0
sodium bicarbonate	medium	1	1
etomidate	low	1	0
tranilast	low	1	0
hydrocodone	medium	2	1
oxycodone	medium	1	1
piperidines	low	1	0
warfarin	low	1	0
exudates	low	1	0

Protein Targets (503)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	8	0	0	8
ATAD5 protein, partial	7	0	0	7
GLS protein	5	0	0	5
Microtubule-associated protein tau	5	0	0	5
Smad3	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
thyroid stimulating hormone receptor	3	0	0	3
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
progesterone receptor	10	0	0	10
EWS/FLI fusion protein	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
retinoid X nuclear receptor alpha	8	0	0	8
estrogen-related nuclear receptor alpha	12	0	0	12
estrogen nuclear receptor alpha	17	0	0	17
peroxisome proliferator activated receptor gamma	7	0	0	7
aryl hydrocarbon receptor	8	0	0	8
chromobox protein homolog 1	11	0	0	11
thyroid hormone receptor beta isoform 2	9	0	0	9
peripheral myelin protein 22	5	0	0	5
cytochrome P450 3A4 isoform 1	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	9	0	0	9
ATP-binding cassette sub-family C member 3	0	9	0	9
Multidrug resistance-associated protein 4	0	9	0	9
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Bile salt export pump	0	18	0	18
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	5	0	5
Carbonic anhydrase 2	0	6	0	6
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	2	0	3
Prostaglandin G/H synthase 1	0	5	0	5
Carbonic anhydrase 3	0	2	0	2
Cytochrome P450 3A4	0	3	0	3
Cytochrome P450 2D6	0	4	0	4
Cytochrome P450 2C9	0	9	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	9	0	0	9
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	9	0	0	9
Gamma-aminobutyric acid receptor subunit gamma-2	9	0	0	9
UDP-glucuronosyltransferase 1-6	0	2	0	3
Glutamate receptor 2	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-3	9	0	0	9
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	3
Carbonic anhydrase 4	0	3	0	3
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-2	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-4	9	0	0	9
Gamma-aminobutyric acid receptor subunit gamma-3	9	0	0	9
Gamma-aminobutyric acid receptor subunit alpha-6	9	0	0	9
Carbonic anhydrase 5A, mitochondrial	0	3	0	3
Prostaglandin G/H synthase 2	0	5	1	8
Carbonic anhydrase 7	0	2	0	2
Nuclear receptor ROR-gamma	2	0	0	2
Cytochrome P450 2J2	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	9	1	0	10
Gamma-aminobutyric acid receptor subunit beta-3	9	0	0	9
Gamma-aminobutyric acid receptor subunit beta-2	9	0	0	9
Carbonic anhydrase 9	0	5	0	5
GABA theta subunit	9	0	0	9
Canalicular multispecific organic anion transporter 1	0	9	0	9
Carbonic anhydrase 15	0	2	0	2
Carbonic anhydrase 13	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	9	0	0	9
Carbonic anhydrase 14	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	3	0	3
toxin B	0	0	0	1
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	0	1	1
Tyrosine-protein kinase Fyn	0	0	1	1
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	9	0	0	9
AR protein	16	0	0	16
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
glucocorticoid receptor [Homo sapiens]	16	0	0	16
G	7	0	0	7
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
Interferon beta	9	0	0	9
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
Aromatase	0	4	0	4
Amine oxidase [flavin-containing] A	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	2	0	2
Spike glycoprotein	5	0	0	5
Inositol hexakisphosphate kinase 1	7	0	0	7
cytochrome P450 2C9, partial	7	0	0	7
thioredoxin reductase	5	0	0	5
TDP1 protein	9	0	0	9
arylsulfatase A	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	12	0	0	12
Bloom syndrome protein isoform 1	3	0	0	3
D(1A) dopamine receptor	2	0	0	2
lamin isoform A-delta10	10	0	0	10
neuropeptide S receptor isoform A	3	0	0	3
pregnane X receptor	3	0	0	3
GLI family zinc finger 3	12	0	0	12
farnesoid X nuclear receptor	3	0	0	3
pregnane X nuclear receptor	10	0	0	10
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
IDH1	8	0	0	8
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
thyroid hormone receptor beta isoform a	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	7	0	0	7
Glucocorticoid receptor	0	10	0	10
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	1	2
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Cruzipain	1	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	2	0	2
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
glp-1 receptor, partial	5	0	0	5
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
SMAD family member 2	4	0	0	4
USP1 protein, partial	6	0	0	6
PPM1D protein	4	0	0	4
SMAD family member 3	4	0	0	4
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	2	0	0	2
cytochrome P450 2D6	6	0	0	6
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
67.9K protein	2	0	0	2
peroxisome proliferator-activated receptor delta	4	0	0	4
Carbonic anhydrase	0	1	0	1
Rac1 protein	0	0	1	1
caspase-3	2	0	0	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
thyroid stimulating hormone receptor	2	0	0	2
activating transcription factor 6	3	0	0	3
thyrotropin-releasing hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
v-jun sarcoma virus 17 oncogene homolog (avian)	3	0	0	3
Histone H2A.x	2	0	0	2
Caspase-7	1	0	0	1
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
caspase-3	1	0	0	1
heat shock protein beta-1	5	0	0	5
geminin	12	0	0	12
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	2	0	2
Cellular tumor antigen p53	7	0	0	7
Procathepsin L	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Adenosine receptor A3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Beta-3 adrenergic receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	5	2	7
Calpain-2 catalytic subunit	0	1	0	1
Alpha-2B adrenergic receptor	0	4	1	6
5-hydroxytryptamine receptor 1A	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Sodium-dependent noradrenaline transporter	0	2	1	3
Adenosine receptor A1	0	2	0	2
Cruzipain	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	0	1	1
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	4	0	4
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	3	0	4
Carbonic anhydrase	0	2	0	2
Alpha-1A adrenergic receptor	0	5	2	7
Urotensin-2 receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
D(2) dopamine receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	5	0	5
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	3	0	3
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Histone deacetylase 1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	4
Carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Histone deacetylase 2	0	1	0	1
Carbonic anhydrase 4	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	9	0	0	9
Histone deacetylase 8	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
endonuclease IV	1	0	0	1
dopamine D1 receptor	2	0	0	2
regulator of G-protein signaling 4	2	0	0	2
peripheral myelin protein 22 isoform 1	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
flap endonuclease 1	3	0	0	3
survival motor neuron protein isoform d	5	0	0	5
M-phase phosphoprotein 8	2	0	0	2
muscarinic acetylcholine receptor M1	3	0	0	3
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	4	0	0	4
Multidrug and toxin extrusion protein 1	0	3	0	3
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Dihydrofolate reductase	0	2	0	2
Fatty acid-binding protein, liver	0	3	0	3
Transthyretin	0	0	1	3
Albumin	0	3	3	6
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	3	1	4
Aldo-keto reductase family 1 member B1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
lethal factor (plasmid)	1	0	0	1
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Acetylcholine receptor subunit delta	0	1	0	1
Acetylcholine receptor subunit alpha	0	1	0	1
Acetylcholine receptor subunit gamma	0	1	0	1
Acetylcholine receptor subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Cytochrome P450 11B2, mitochondrial	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Transporter	0	1	0	1
phosphopantetheinyl transferase	4	0	0	4
Solute carrier family 22 member 1	0	2	0	2
Mu-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	1	1	2
Mas-related G-protein coupled receptor member X2	0	0	1	1
Luciferase	4	0	0	4
NFKB1 protein, partial	3	0	0	3
nonstructural protein 1	3	0	0	3
transcriptional regulator ERG isoform 3	1	0	0	1
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
DNA polymerase kappa isoform 1	1	0	0	1
muscleblind-like protein 1 isoform 1	5	0	0	5
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Albumin	0	1	0	2
Albumin	0	0	2	2
Cholinesterase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Acetylcholinesterase	0	1	0	1
Caspase-1	0	2	0	2
Adenosine receptor A2a	0	1	1	2
Substance-P receptor	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
acetylcholinesterase	3	0	0	3
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Acetylcholinesterase	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	2	0	2
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
ras-related protein Rab-9A	2	0	0	2
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
GALC protein	1	0	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
cytochrome P450 2C19 precursor	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
mitogen-activated protein kinase 1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	1	0	0	1
Cytochrome P450 2C19	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
vitamin D3 receptor isoform VDRA	2	0	0	2
core-binding factor subunit beta isoform 2	1	0	0	1
Estrogen receptor	0	1	0	1
Steryl-sulfatase	0	1	0	1
Chain A, Beta-lactamase	3	0	0	3
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Ferritin light chain	1	0	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Fumarate hydratase	1	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
polyprotein	1	0	0	1
luciferase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
DNA polymerase beta	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
Vpr	1	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	3	2	6
Alpha-synuclein	1	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Inositol monophosphatase 1	1	0	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
ATP-dependent phosphofructokinase	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Androgen receptor	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Kappa-type opioid receptor	0	0	1	1
Kappa-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	0	1	1
Kappa-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
ClpP	1	0	0	1
Hsf1 protein	0	0	1	1
estrogen receptor beta isoform 1	0	1	0	1
Alpha-1A adrenergic receptor	0	0	1	1
5-hydroxytryptamine receptor 4	0	2	0	2
Alpha-2A adrenergic receptor	0	2	1	4
Angiotensin-converting enzyme	0	2	0	2
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	2	1	4
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	2	2	4
Alpha-2C adrenergic receptor	0	2	2	4
Alpha-2A adrenergic receptor	0	2	2	4
Alpha-1D adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-1A adrenergic receptor	0	2	1	3
Histamine H1 receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 2B	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Nischarin	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
MSH	0	0	0	1
Thrombopoietin	1	0	0	1
Parkin	1	0	0	1
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
nuclear receptor ROR-gamma isoform 1	2	0	0	2
pyruvate kinase PKM isoform b	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Ornithine decarboxylase	1	0	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (145)

Protein Targets (503)

Flexor Tendon Entrapment

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (145)

Drugs Studied (49)

Protein Targets (503)