| Assay ID | Title | Year | Journal | Article |
|---|
| AID737826 | Downregulation of iNOS expression in LPS-treated mouse BV2 cells at 1 to 10 uM incubated for 30 mins prior to LPS challenge measured after 6 hrs by Western blot analysis | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID737830 | Cytotoxicity against mouse BV2 cells assessed as cell viability at 20 uM by MTT assay | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID737831 | Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 10 mins by Griess assay relative to control | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID639582 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decrease TNFalpha levels at 0.5 mg/ear measured at 24 hrs by ELISA relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID737829 | Anti-neuroinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID639585 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decrease IL2 levels at 0.5 mg/ear measured after 72 hrs by ELISA relative to 24 hrs | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID639630 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced MMP9 expression at 25 uM by Western blotting relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1176142 | Cytotoxicity against mouse RAW264.7 cells at 50 uM by MTT assay | 2015 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 25, Issue:2
| Anti-inflammatory components of Chrysanthemum indicum flowers. |
| AID639589 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decreased COX2 expression at 0.5 mg/ear after at 72 hrs by Western blotting relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID639581 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decrease IL1-beta levels at 0.5 mg/ear measured at 24 hrs by ELISA relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1374929 | Inhibition of PTP1B (unknown origin) | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Identification of caffeoylquinic acid derivatives as natural protein tyrosine phosphatase 1B inhibitors from Artemisia princeps. |
| AID639530 | Antihypersensitivity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as inhibition of edema at 0.5 mg/ear applied tropically after 30 mins, 24 hrs and 48 hrs of TNCB challenge measured after 24 hrs relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID639632 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced MMP9 expression at 100 uM by Western blotting relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1176144 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production at 0.4 to 10 uM after 24 hrs by Griess assay | 2015 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 25, Issue:2
| Anti-inflammatory components of Chrysanthemum indicum flowers. |
| AID737822 | Reduction of SNP-induced nitrite accumulation at 1 to 10 uM after 180 mins by Griess assay | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID1293877 | Competitive inhibition of HDAC in human HeLa nuclear cells at 10 to 25 uM using Boc-acetyl-lysine-AMC as substrate after 30 mins by Lineweaver-Burk plot analysis | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9
| Identification of new quinic acid derivatives as histone deacetylase inhibitors by fluorescence-based cellular assay. |
| AID1293878 | Inhibition of HDAC in human HeLa nuclear extract assessed as accumulation of acetylated histone H3 at 0.1 to 100 uM after 24 hrs by western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9
| Identification of new quinic acid derivatives as histone deacetylase inhibitors by fluorescence-based cellular assay. |
| AID402013 | Inhibition of collagenase type 5 | 2005 | Journal of natural products, May, Volume: 68, Issue:5
| Collagenase inhibitory quinic acid esters from Ipomoea pes-caprae. |
| AID639588 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decreased COX2 expression at 0.5 mg/ear after at 24 hrs by Western blotting relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1293875 | Inhibition of HDAC in human HeLa cells using Boc-Lys(AC)-AMC as substrate after 24 to 48 hrs by spectrofluorometry | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9
| Identification of new quinic acid derivatives as histone deacetylase inhibitors by fluorescence-based cellular assay. |
| AID639629 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced MMP9 expression by Western blotting | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID639628 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as inhibition of MMP9 production at 0.5 mg/ear measured at 24 hrs by Western blot analysis relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1176145 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNFalpha production at 0.4 to 10 uM by ELISA | 2015 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 25, Issue:2
| Anti-inflammatory components of Chrysanthemum indicum flowers. |
| AID1293873 | Inhibition of HDAC in mouse C127-LT cells assessed as activation of EGFP expression at 10 uM after 24 hrs by fluorescence microscopy | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9
| Identification of new quinic acid derivatives as histone deacetylase inhibitors by fluorescence-based cellular assay. |
| AID737827 | Cytotoxicity against mouse RAW264.7 cells assessed as decrease in cell viability at 20 uM | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID639583 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decrease IL1-beta levels at 0.5 mg/ear measured at 72 hrs by ELISA relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID639586 | Antihypersensitivity activity against TNCB-induced contact hypersensitivity in BALB/c mouse ear assessed as decrease IL4 levels at 0.5 mg/ear measured after 24 to 72 hrs by ELISA | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1293874 | Inhibition of HDAC in human HeLa nuclear extract using fluor de lys as substrate after 10 to 15 mins by spectrofluorometry | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9
| Identification of new quinic acid derivatives as histone deacetylase inhibitors by fluorescence-based cellular assay. |
| AID737824 | Inhibition of iNOS in LPS-treated mouse BV2 cells assessed as decrease in nitrite level at 1 to 5 uM after 12 hrs by Griess assay | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. |
| AID639631 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced MMP9 expression at 50 uM by Western blotting relative to control | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5
| Phenolic substances from Phagnalon rupestre protect against 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity. |
| AID1495179 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM assessed as downregulation of Ctsk mRNA expression at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495187 | Inhibition of RANKL-induced AKT phosphorylation in ICR mouse BMDM at 5 uM preincubated for 1 hr followed by RANKL stimulation measured after 30 mins by Western blot method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495178 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM assessed as downregulation of Acp5 mRNA expression at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495175 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM at 1 uM after 4 days by TRAP staining method relative to control | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495177 | Growth inhibition of ICR mouse BMDM up to 10 uM after 3 days by MTT assay | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495188 | Inhibition of RANKL-mediated decrease in Irf8 mRNA expression in ICR mouse BMDM at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495189 | Inhibition of RANKL-mediated decrease in Bcl6 mRNA expression in ICR mouse BMDM at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495185 | Inhibition of RANKL-induced p38 phosphorylation in ICR mouse BMDM at 5 uM preincubated for 1 hr followed by RANKL stimulation measured after 5 to 30 mins by Western blot method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495176 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM at 5 to 10 uM after 4 days by TRAP staining method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495182 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM assessed as downregulation of Nfatc1 expression at 5 uM after 3 days by Western blot method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495183 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM assessed as decrease in number of cells with nuclear Nfatc1 at 5 uM by rhodamine-conjugated phalloidin/DAPI staining-based immunofluorescence method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495186 | Inhibition of RANKL-induced ERK phosphorylation in ICR mouse BMDM at 5 uM preincubated for 1 hr followed by RANKL stimulation measured after 5 to 30 mins by Western blot method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495184 | Effect on bone-resorbing function of osteoclast derived from M-CSF/RANKL-induced ICR mouse BMDM assessed as change in size of resorption pit area at 5 uM after 2 days by hematoxylin staining-based assay | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495181 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM assessed as downregulation of Nfatc1 mRNA expression at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495180 | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in ICR mouse BMDM assessed as downregulation of Dcstamp mRNA expression at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| AID1495190 | Inhibition of RANKL-mediated decrease in Mafb mRNA expression in ICR mouse BMDM at 5 uM by qRT-PCR method | 2018 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 28, Issue:10
| Inhibitory effects of methyl-3,5-di-O-caffeoyl-epi-quinate on RANKL-induced osteoclast differentiation. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |