Compounds > albocycline
Page last updated: 2024-12-11

albocycline

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Description

albocycline: macrolide antibiotic isolated from Streptomyces bruneogriseus nov. sp. MCRL-0129; specifically anti-staphylococcal, including antibiotic-resistant strains; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6440973
CHEMBL ID4128170
CHEBI ID182469
MeSH IDM0049024

Synonyms (22)

Synonym
albocyclin
ingramycin
cineromycin-b-methylaether
ta-2407
albocycline
(3e,5r,6e,8s,9e,13s,14r)-5-hydroxy-8-methoxy-5,9,13,14-tetramethyl-1-oxacyclotetradeca-3,6,9-trien-2-one
25129-91-3
CHEBI:182469
ACON1_001110
MEGXM0_000381
ACON0_000812
HB3748
albocycline, >=95% (lc/ms-elsd)
J-015824
NCGC00385282-01
chembl4128170 ,
bdbm50274417
DTXSID601113147
(3e,5r,6e,8s,9e,13s,14r)-5-hydroxy-8-methoxy-5,9,13,14-tetramethyloxacyclotetradeca-3,6,9-trien-2-one
nsc-815335
nsc815335
AKOS040746522

Research Excerpts

Overview

Albocycline (ALB) is a macrolactone natural product with potent activity against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant S.

ExcerptReferenceRelevance
"Albocycline (ALB) is a unique macrolactone natural product with potent, narrow-spectrum activity against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate (VISA), and vancomycin-resistant S. "( Synthesis and biological evaluation of semi-synthetic albocycline analogs.
Andrade, RB; Daher, SS; Dunman, PM; Franklin, KP; Scherzi, T, 2020)		2.25
"Albocycline (ALB) is a macrolactone natural product with potent activity against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant S."( Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
Andrade, RB; D'Ambrosio, EA; Daher, SS; Dunman, PM; Grimes, CL; Scherzi, T, 2021)		1.62

Bioavailability

ExcerptReferenceRelevance
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019)		0.51
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
macrolideA macrocyclic lactone with a ring of twelve or more members derived from a polyketide.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (56)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
30S ribosomal protein S6Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S7Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L15Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L10Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L11Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L7/L12Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L19Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L1Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L20Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L27Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L28Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L29Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L31Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L31 type BEscherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L32Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L33Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L34Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L35Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L36Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S10Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S11Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S12Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S13Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S16Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S18Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S19Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S20Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S2Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S3Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S4Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S5Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S8Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S9Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L13Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L14Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L16Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L23Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S15Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L17Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L21Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L30Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L6Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S14Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S17Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S1Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L18Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L2Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L3Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L24Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L4Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L22Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L5Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
30S ribosomal protein S21Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L25Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
50S ribosomal protein L36 2Escherichia coli K-12Kd0.00240.00060.02310.0840AID1694436
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (37)

Processvia Protein(s)Taxonomy
cytoplasmic translation30S ribosomal protein S6Escherichia coli K-12
translation30S ribosomal protein S6Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S7Escherichia coli K-12
negative regulation of translation30S ribosomal protein S7Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S7Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S7Escherichia coli K-12
translation30S ribosomal protein S7Escherichia coli K-12
negative regulation of translation30S ribosomal protein S7Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L15Escherichia coli K-12
translation50S ribosomal protein L15Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L10Escherichia coli K-12
translation50S ribosomal protein L10Escherichia coli K-12
regulation of translation50S ribosomal protein L10Escherichia coli K-12
negative regulation of translation50S ribosomal protein L10Escherichia coli K-12
translation50S ribosomal protein L11Escherichia coli K-12
translational termination50S ribosomal protein L11Escherichia coli K-12
stringent response50S ribosomal protein L11Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L11Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L11Escherichia coli K-12
translation50S ribosomal protein L11Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L7/L12Escherichia coli K-12
translation50S ribosomal protein L7/L12Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L19Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L19Escherichia coli K-12
translation50S ribosomal protein L19Escherichia coli K-12
negative regulation of translational initiation50S ribosomal protein L1Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L1Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L1Escherichia coli K-12
translation50S ribosomal protein L1Escherichia coli K-12
regulation of translation50S ribosomal protein L1Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L20Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L20Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L20Escherichia coli K-12
translation50S ribosomal protein L20Escherichia coli K-12
negative regulation of translation50S ribosomal protein L20Escherichia coli K-12
cytosolic ribosome assembly50S ribosomal protein L27Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L27Escherichia coli K-12
regulation of cell growth50S ribosomal protein L27Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L27Escherichia coli K-12
translation50S ribosomal protein L27Escherichia coli K-12
positive regulation of ribosome biogenesis50S ribosomal protein L27Escherichia coli K-12
assembly of large subunit precursor of preribosome50S ribosomal protein L27Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L28Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L28Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L28Escherichia coli K-12
translation50S ribosomal protein L28Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L29Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L29Escherichia coli K-12
translation50S ribosomal protein L29Escherichia coli K-12
translation50S ribosomal protein L31Escherichia coli K-12
translational initiation50S ribosomal protein L31Escherichia coli K-12
negative regulation of cytoplasmic translational initiation50S ribosomal protein L31Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L31Escherichia coli K-12
translation50S ribosomal protein L31Escherichia coli K-12
cellular response to zinc ion starvation50S ribosomal protein L31 type BEscherichia coli K-12
cytoplasmic translation50S ribosomal protein L31 type BEscherichia coli K-12
translation50S ribosomal protein L31 type BEscherichia coli K-12
response to reactive oxygen species50S ribosomal protein L32Escherichia coli K-12
response to radiation50S ribosomal protein L32Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L32Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L32Escherichia coli K-12
translation50S ribosomal protein L32Escherichia coli K-12
response to antibiotic50S ribosomal protein L33Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L33Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L33Escherichia coli K-12
translation50S ribosomal protein L33Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L34Escherichia coli K-12
translation50S ribosomal protein L34Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L35Escherichia coli K-12
translation50S ribosomal protein L35Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L36Escherichia coli K-12
translation50S ribosomal protein L36Escherichia coli K-12
transcription antitermination30S ribosomal protein S10Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S10Escherichia coli K-12
translation30S ribosomal protein S10Escherichia coli K-12
transcription antitermination30S ribosomal protein S10Escherichia coli K-12
regulation of DNA-templated transcription elongation30S ribosomal protein S10Escherichia coli K-12
ribosome biogenesis30S ribosomal protein S10Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S11Escherichia coli K-12
translation30S ribosomal protein S11Escherichia coli K-12
Group I intron splicing30S ribosomal protein S12Escherichia coli K-12
positive regulation of RNA splicing30S ribosomal protein S12Escherichia coli K-12
RNA folding30S ribosomal protein S12Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S12Escherichia coli K-12
translation30S ribosomal protein S12Escherichia coli K-12
response to antibiotic30S ribosomal protein S12Escherichia coli K-12
maintenance of translational fidelity30S ribosomal protein S12Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S13Escherichia coli K-12
translation30S ribosomal protein S13Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S16Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S16Escherichia coli K-12
DNA metabolic process30S ribosomal protein S16Escherichia coli K-12
translation30S ribosomal protein S16Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S18Escherichia coli K-12
translation30S ribosomal protein S18Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S19Escherichia coli K-12
translation30S ribosomal protein S19Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S19Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S20Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S20Escherichia coli K-12
translation30S ribosomal protein S20Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S2Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S2Escherichia coli K-12
translation30S ribosomal protein S2Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S3Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S3Escherichia coli K-12
translation30S ribosomal protein S3Escherichia coli K-12
transcription antitermination30S ribosomal protein S4Escherichia coli K-12
negative regulation of translational initiation30S ribosomal protein S4Escherichia coli K-12
maintenance of translational fidelity30S ribosomal protein S4Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S4Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S4Escherichia coli K-12
DNA-templated transcription termination30S ribosomal protein S4Escherichia coli K-12
translation30S ribosomal protein S4Escherichia coli K-12
regulation of translation30S ribosomal protein S4Escherichia coli K-12
transcription antitermination30S ribosomal protein S4Escherichia coli K-12
ribosome biogenesis30S ribosomal protein S4Escherichia coli K-12
response to antibiotic30S ribosomal protein S4Escherichia coli K-12
ribosomal small subunit biogenesis30S ribosomal protein S4Escherichia coli K-12
maintenance of translational fidelity30S ribosomal protein S5Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S5Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S5Escherichia coli K-12
translation30S ribosomal protein S5Escherichia coli K-12
response to antibiotic30S ribosomal protein S5Escherichia coli K-12
regulation of mRNA stability30S ribosomal protein S8Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S8Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S8Escherichia coli K-12
translation30S ribosomal protein S8Escherichia coli K-12
regulation of translation30S ribosomal protein S8Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S9Escherichia coli K-12
translation30S ribosomal protein S9Escherichia coli K-12
negative regulation of translation50S ribosomal protein L13Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L13Escherichia coli K-12
translation50S ribosomal protein L13Escherichia coli K-12
negative regulation of translation50S ribosomal protein L13Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L14Escherichia coli K-12
translation50S ribosomal protein L14Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L16Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L16Escherichia coli K-12
translation50S ribosomal protein L16Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L23Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L23Escherichia coli K-12
translation50S ribosomal protein L23Escherichia coli K-12
translation30S ribosomal protein S15Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S15Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S15Escherichia coli K-12
translation30S ribosomal protein S15Escherichia coli K-12
regulation of translation30S ribosomal protein S15Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L17Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L17Escherichia coli K-12
translation50S ribosomal protein L17Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L21Escherichia coli K-12
translation50S ribosomal protein L21Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L30Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L30Escherichia coli K-12
translation50S ribosomal protein L30Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L6Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L6Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L6Escherichia coli K-12
translation50S ribosomal protein L6Escherichia coli K-12
response to antibiotic50S ribosomal protein L6Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S14Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S14Escherichia coli K-12
translation30S ribosomal protein S14Escherichia coli K-12
response to antibiotic30S ribosomal protein S17Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S17Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S17Escherichia coli K-12
translation30S ribosomal protein S17Escherichia coli K-12
response to antibiotic30S ribosomal protein S17Escherichia coli K-12
translation30S ribosomal protein S1Escherichia coli K-12
RNA secondary structure unwinding30S ribosomal protein S1Escherichia coli K-12
negative regulation of cytoplasmic translation30S ribosomal protein S1Escherichia coli K-12
positive regulation of cytoplasmic translation30S ribosomal protein S1Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S1Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S1Escherichia coli K-12
translation30S ribosomal protein S1Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L18Escherichia coli K-12
translation50S ribosomal protein L18Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L2Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L2Escherichia coli K-12
translation50S ribosomal protein L2Escherichia coli K-12
negative regulation of DNA-templated DNA replication initiation50S ribosomal protein L2Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L3Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L3Escherichia coli K-12
translation50S ribosomal protein L3Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L24Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L24Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L24Escherichia coli K-12
translation50S ribosomal protein L24Escherichia coli K-12
transcriptional attenuation50S ribosomal protein L4Escherichia coli K-12
negative regulation of cytoplasmic translation50S ribosomal protein L4Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L4Escherichia coli K-12
DNA-templated transcription termination50S ribosomal protein L4Escherichia coli K-12
translation50S ribosomal protein L4Escherichia coli K-12
regulation of translation50S ribosomal protein L4Escherichia coli K-12
negative regulation of translation50S ribosomal protein L4Escherichia coli K-12
ribosome assembly50S ribosomal protein L4Escherichia coli K-12
negative regulation of DNA-templated transcription50S ribosomal protein L4Escherichia coli K-12
response to antibiotic50S ribosomal protein L4Escherichia coli K-12
translation50S ribosomal protein L22Escherichia coli K-12
cytosolic ribosome assembly50S ribosomal protein L22Escherichia coli K-12
assembly of large subunit precursor of preribosome50S ribosomal protein L22Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L22Escherichia coli K-12
translation50S ribosomal protein L22Escherichia coli K-12
ribosome assembly50S ribosomal protein L22Escherichia coli K-12
response to antibiotic50S ribosomal protein L22Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L5Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L5Escherichia coli K-12
translation50S ribosomal protein L5Escherichia coli K-12
ribosomal small subunit assembly30S ribosomal protein S21Escherichia coli K-12
cytoplasmic translation30S ribosomal protein S21Escherichia coli K-12
translation30S ribosomal protein S21Escherichia coli K-12
translation50S ribosomal protein L25Escherichia coli K-12
response to radiation50S ribosomal protein L25Escherichia coli K-12
negative regulation of translation50S ribosomal protein L25Escherichia coli K-12
ribosomal large subunit assembly50S ribosomal protein L25Escherichia coli K-12
cytoplasmic translation50S ribosomal protein L25Escherichia coli K-12
translation50S ribosomal protein L25Escherichia coli K-12
translation50S ribosomal protein L36 2Escherichia coli K-12
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (29)

Processvia Protein(s)Taxonomy
structural constituent of ribosome30S ribosomal protein S6Escherichia coli K-12
protein binding30S ribosomal protein S6Escherichia coli K-12
rRNA binding30S ribosomal protein S6Escherichia coli K-12
mRNA 5'-UTR binding30S ribosomal protein S6Escherichia coli K-12
small ribosomal subunit rRNA binding30S ribosomal protein S6Escherichia coli K-12
tRNA binding30S ribosomal protein S7Escherichia coli K-12
RNA binding30S ribosomal protein S7Escherichia coli K-12
mRNA binding30S ribosomal protein S7Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S7Escherichia coli K-12
protein binding30S ribosomal protein S7Escherichia coli K-12
rRNA binding30S ribosomal protein S7Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L15Escherichia coli K-12
protein binding50S ribosomal protein L15Escherichia coli K-12
rRNA binding50S ribosomal protein L15Escherichia coli K-12
GTPase activity50S ribosomal protein L10Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L10Escherichia coli K-12
protein binding50S ribosomal protein L10Escherichia coli K-12
rRNA binding50S ribosomal protein L10Escherichia coli K-12
ribosome binding50S ribosomal protein L10Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L10Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L11Escherichia coli K-12
protein binding50S ribosomal protein L11Escherichia coli K-12
rRNA binding50S ribosomal protein L11Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L11Escherichia coli K-12
GTPase activity50S ribosomal protein L7/L12Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L7/L12Escherichia coli K-12
protein binding50S ribosomal protein L7/L12Escherichia coli K-12
protein homodimerization activity50S ribosomal protein L7/L12Escherichia coli K-12
ribosome binding50S ribosomal protein L7/L12Escherichia coli K-12
mRNA binding50S ribosomal protein L7/L12Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L19Escherichia coli K-12
rRNA binding50S ribosomal protein L19Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L19Escherichia coli K-12
tRNA binding50S ribosomal protein L1Escherichia coli K-12
RNA binding50S ribosomal protein L1Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L1Escherichia coli K-12
protein binding50S ribosomal protein L1Escherichia coli K-12
rRNA binding50S ribosomal protein L1Escherichia coli K-12
mRNA regulatory element binding translation repressor activity50S ribosomal protein L20Escherichia coli K-12
mRNA binding50S ribosomal protein L20Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L20Escherichia coli K-12
rRNA binding50S ribosomal protein L20Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L20Escherichia coli K-12
tRNA binding50S ribosomal protein L27Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L27Escherichia coli K-12
protein binding50S ribosomal protein L27Escherichia coli K-12
rRNA binding50S ribosomal protein L27Escherichia coli K-12
ribosome binding50S ribosomal protein L27Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L28Escherichia coli K-12
protein binding50S ribosomal protein L28Escherichia coli K-12
rRNA binding50S ribosomal protein L28Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L29Escherichia coli K-12
rRNA binding50S ribosomal protein L29Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L31Escherichia coli K-12
zinc ion binding50S ribosomal protein L31Escherichia coli K-12
rRNA binding50S ribosomal protein L31Escherichia coli K-12
metal ion binding50S ribosomal protein L31Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L31 type BEscherichia coli K-12
structural constituent of ribosome50S ribosomal protein L32Escherichia coli K-12
protein binding50S ribosomal protein L32Escherichia coli K-12
tRNA binding50S ribosomal protein L33Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L33Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L34Escherichia coli K-12
protein binding50S ribosomal protein L34Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L35Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L36Escherichia coli K-12
tRNA binding30S ribosomal protein S10Escherichia coli K-12
transcription antitermination factor activity, RNA binding30S ribosomal protein S10Escherichia coli K-12
RNA binding30S ribosomal protein S10Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S10Escherichia coli K-12
protein binding30S ribosomal protein S10Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S11Escherichia coli K-12
protein binding30S ribosomal protein S11Escherichia coli K-12
rRNA binding30S ribosomal protein S11Escherichia coli K-12
small ribosomal subunit rRNA binding30S ribosomal protein S11Escherichia coli K-12
tRNA binding30S ribosomal protein S12Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S12Escherichia coli K-12
protein binding30S ribosomal protein S12Escherichia coli K-12
rRNA binding30S ribosomal protein S12Escherichia coli K-12
misfolded RNA binding30S ribosomal protein S12Escherichia coli K-12
tRNA binding30S ribosomal protein S13Escherichia coli K-12
RNA binding30S ribosomal protein S13Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S13Escherichia coli K-12
protein binding30S ribosomal protein S13Escherichia coli K-12
rRNA binding30S ribosomal protein S13Escherichia coli K-12
four-way junction DNA binding30S ribosomal protein S16Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S16Escherichia coli K-12
endonuclease activity30S ribosomal protein S16Escherichia coli K-12
DNA endonuclease activity30S ribosomal protein S16Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S18Escherichia coli K-12
protein binding30S ribosomal protein S18Escherichia coli K-12
rRNA binding30S ribosomal protein S18Escherichia coli K-12
mRNA 5'-UTR binding30S ribosomal protein S18Escherichia coli K-12
small ribosomal subunit rRNA binding30S ribosomal protein S18Escherichia coli K-12
tRNA binding30S ribosomal protein S19Escherichia coli K-12
RNA binding30S ribosomal protein S19Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S19Escherichia coli K-12
rRNA binding30S ribosomal protein S19Escherichia coli K-12
RNA binding30S ribosomal protein S20Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S20Escherichia coli K-12
ornithine decarboxylase inhibitor activity30S ribosomal protein S20Escherichia coli K-12
rRNA binding30S ribosomal protein S20Escherichia coli K-12
small ribosomal subunit rRNA binding30S ribosomal protein S20Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S2Escherichia coli K-12
protein binding30S ribosomal protein S2Escherichia coli K-12
zinc ion binding30S ribosomal protein S2Escherichia coli K-12
RNA binding30S ribosomal protein S3Escherichia coli K-12
mRNA binding30S ribosomal protein S3Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S3Escherichia coli K-12
rRNA binding30S ribosomal protein S3Escherichia coli K-12
mRNA regulatory element binding translation repressor activity30S ribosomal protein S4Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S4Escherichia coli K-12
protein binding30S ribosomal protein S4Escherichia coli K-12
rRNA binding30S ribosomal protein S4Escherichia coli K-12
mRNA 5'-UTR binding30S ribosomal protein S4Escherichia coli K-12
RNA binding30S ribosomal protein S5Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S5Escherichia coli K-12
protein binding30S ribosomal protein S5Escherichia coli K-12
rRNA binding30S ribosomal protein S5Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S8Escherichia coli K-12
rRNA binding30S ribosomal protein S8Escherichia coli K-12
tRNA binding30S ribosomal protein S9Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S9Escherichia coli K-12
RNA binding30S ribosomal protein S9Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L13Escherichia coli K-12
zinc ion binding50S ribosomal protein L13Escherichia coli K-12
mRNA 5'-UTR binding50S ribosomal protein L13Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L13Escherichia coli K-12
mRNA binding50S ribosomal protein L13Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L14Escherichia coli K-12
protein binding50S ribosomal protein L14Escherichia coli K-12
rRNA binding50S ribosomal protein L14Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L14Escherichia coli K-12
tRNA binding50S ribosomal protein L16Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L16Escherichia coli K-12
rRNA binding50S ribosomal protein L16Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L23Escherichia coli K-12
protein binding50S ribosomal protein L23Escherichia coli K-12
rRNA binding50S ribosomal protein L23Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S15Escherichia coli K-12
rRNA binding30S ribosomal protein S15Escherichia coli K-12
small ribosomal subunit rRNA binding30S ribosomal protein S15Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L17Escherichia coli K-12
protein binding50S ribosomal protein L17Escherichia coli K-12
RNA binding50S ribosomal protein L21Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L21Escherichia coli K-12
rRNA binding50S ribosomal protein L21Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L30Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L6Escherichia coli K-12
rRNA binding50S ribosomal protein L6Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L6Escherichia coli K-12
tRNA binding30S ribosomal protein S14Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S14Escherichia coli K-12
rRNA binding30S ribosomal protein S14Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S17Escherichia coli K-12
zinc ion binding30S ribosomal protein S17Escherichia coli K-12
rRNA binding30S ribosomal protein S17Escherichia coli K-12
molecular adaptor activity30S ribosomal protein S17Escherichia coli K-12
small ribosomal subunit rRNA binding30S ribosomal protein S17Escherichia coli K-12
RNA binding30S ribosomal protein S1Escherichia coli K-12
single-stranded RNA binding30S ribosomal protein S1Escherichia coli K-12
mRNA binding30S ribosomal protein S1Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S1Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L18Escherichia coli K-12
5S rRNA binding50S ribosomal protein L18Escherichia coli K-12
rRNA binding50S ribosomal protein L18Escherichia coli K-12
RNA binding50S ribosomal protein L2Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L2Escherichia coli K-12
protein binding50S ribosomal protein L2Escherichia coli K-12
zinc ion binding50S ribosomal protein L2Escherichia coli K-12
transferase activity50S ribosomal protein L2Escherichia coli K-12
rRNA binding50S ribosomal protein L2Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L3Escherichia coli K-12
protein binding50S ribosomal protein L3Escherichia coli K-12
rRNA binding50S ribosomal protein L3Escherichia coli K-12
RNA binding50S ribosomal protein L24Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L24Escherichia coli K-12
protein binding50S ribosomal protein L24Escherichia coli K-12
rRNA binding50S ribosomal protein L24Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L24Escherichia coli K-12
RNA-binding transcription regulator activity50S ribosomal protein L4Escherichia coli K-12
DNA binding50S ribosomal protein L4Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L4Escherichia coli K-12
protein binding50S ribosomal protein L4Escherichia coli K-12
rRNA binding50S ribosomal protein L4Escherichia coli K-12
translation repressor activity50S ribosomal protein L4Escherichia coli K-12
mRNA 5'-UTR binding50S ribosomal protein L4Escherichia coli K-12
endoribonuclease inhibitor activity50S ribosomal protein L4Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L22Escherichia coli K-12
protein binding50S ribosomal protein L22Escherichia coli K-12
rRNA binding50S ribosomal protein L22Escherichia coli K-12
large ribosomal subunit rRNA binding50S ribosomal protein L22Escherichia coli K-12
tRNA binding50S ribosomal protein L5Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L5Escherichia coli K-12
5S rRNA binding50S ribosomal protein L5Escherichia coli K-12
rRNA binding50S ribosomal protein L5Escherichia coli K-12
RNA binding50S ribosomal protein L5Escherichia coli K-12
structural constituent of ribosome30S ribosomal protein S21Escherichia coli K-12
rRNA binding30S ribosomal protein S21Escherichia coli K-12
RNA binding50S ribosomal protein L25Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L25Escherichia coli K-12
5S rRNA binding50S ribosomal protein L25Escherichia coli K-12
rRNA binding50S ribosomal protein L25Escherichia coli K-12
structural constituent of ribosome50S ribosomal protein L36 2Escherichia coli K-12
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (12)

Processvia Protein(s)Taxonomy
cytoplasm30S ribosomal protein S6Escherichia coli K-12
cytosol30S ribosomal protein S6Escherichia coli K-12
ribosome30S ribosomal protein S6Escherichia coli K-12
intracellular organelle30S ribosomal protein S6Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S6Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S6Escherichia coli K-12
cytosol30S ribosomal protein S7Escherichia coli K-12
ribosome30S ribosomal protein S7Escherichia coli K-12
membrane30S ribosomal protein S7Escherichia coli K-12
cytoplasm30S ribosomal protein S7Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S7Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S7Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S7Escherichia coli K-12
ribosome30S ribosomal protein S7Escherichia coli K-12
ribosome50S ribosomal protein L15Escherichia coli K-12
cytoplasm50S ribosomal protein L15Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L15Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L15Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L15Escherichia coli K-12
cytosol50S ribosomal protein L10Escherichia coli K-12
ribosome50S ribosomal protein L10Escherichia coli K-12
cytoplasm50S ribosomal protein L10Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L10Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L10Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L10Escherichia coli K-12
cytosol50S ribosomal protein L11Escherichia coli K-12
ribosome50S ribosomal protein L11Escherichia coli K-12
cytoplasm50S ribosomal protein L11Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L11Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L11Escherichia coli K-12
cytoplasm50S ribosomal protein L7/L12Escherichia coli K-12
cytosol50S ribosomal protein L7/L12Escherichia coli K-12
ribosome50S ribosomal protein L7/L12Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L7/L12Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L7/L12Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L7/L12Escherichia coli K-12
cytosol50S ribosomal protein L19Escherichia coli K-12
ribosome50S ribosomal protein L19Escherichia coli K-12
cytoplasm50S ribosomal protein L19Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L19Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L19Escherichia coli K-12
cytosol50S ribosomal protein L1Escherichia coli K-12
ribosome50S ribosomal protein L1Escherichia coli K-12
cytoplasm50S ribosomal protein L1Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L1Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L1Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L1Escherichia coli K-12
cytosol50S ribosomal protein L20Escherichia coli K-12
ribosome50S ribosomal protein L20Escherichia coli K-12
cytoplasm50S ribosomal protein L20Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L20Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L20Escherichia coli K-12
ribosome50S ribosomal protein L27Escherichia coli K-12
cytoplasm50S ribosomal protein L27Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L27Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L27Escherichia coli K-12
cytosol50S ribosomal protein L28Escherichia coli K-12
ribosome50S ribosomal protein L28Escherichia coli K-12
cytoplasm50S ribosomal protein L28Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L28Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L28Escherichia coli K-12
ribosome50S ribosomal protein L29Escherichia coli K-12
cytoplasm50S ribosomal protein L29Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L29Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L29Escherichia coli K-12
cytosol50S ribosomal protein L31Escherichia coli K-12
ribosome50S ribosomal protein L31Escherichia coli K-12
cytoplasm50S ribosomal protein L31Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L31Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L31Escherichia coli K-12
ribosome50S ribosomal protein L31 type BEscherichia coli K-12
cytoplasm50S ribosomal protein L31 type BEscherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L31 type BEscherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L31 type BEscherichia coli K-12
cytosol50S ribosomal protein L32Escherichia coli K-12
ribosome50S ribosomal protein L32Escherichia coli K-12
cytoplasm50S ribosomal protein L32Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L32Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L32Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L32Escherichia coli K-12
cytoplasm50S ribosomal protein L33Escherichia coli K-12
cytosol50S ribosomal protein L33Escherichia coli K-12
ribosome50S ribosomal protein L33Escherichia coli K-12
intracellular organelle50S ribosomal protein L33Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L33Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L33Escherichia coli K-12
ribosome50S ribosomal protein L34Escherichia coli K-12
cytoplasm50S ribosomal protein L34Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L34Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L34Escherichia coli K-12
ribosome50S ribosomal protein L35Escherichia coli K-12
cytoplasm50S ribosomal protein L35Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L35Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L35Escherichia coli K-12
cytoplasm50S ribosomal protein L36Escherichia coli K-12
ribosome50S ribosomal protein L36Escherichia coli K-12
intracellular organelle50S ribosomal protein L36Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L36Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L36Escherichia coli K-12
cytosol30S ribosomal protein S10Escherichia coli K-12
ribosome30S ribosomal protein S10Escherichia coli K-12
cytoplasm30S ribosomal protein S10Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S10Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S10Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S10Escherichia coli K-12
cytosol30S ribosomal protein S11Escherichia coli K-12
ribosome30S ribosomal protein S11Escherichia coli K-12
cytoplasm30S ribosomal protein S11Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S11Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S11Escherichia coli K-12
cytosol30S ribosomal protein S12Escherichia coli K-12
ribosome30S ribosomal protein S12Escherichia coli K-12
cytoplasm30S ribosomal protein S12Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S12Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S12Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S12Escherichia coli K-12
ribosome30S ribosomal protein S12Escherichia coli K-12
cytosol30S ribosomal protein S13Escherichia coli K-12
ribosome30S ribosomal protein S13Escherichia coli K-12
cytoplasm30S ribosomal protein S13Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S13Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S13Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S13Escherichia coli K-12
cytosol30S ribosomal protein S13Escherichia coli K-12
cytoplasm30S ribosomal protein S16Escherichia coli K-12
ribosome30S ribosomal protein S16Escherichia coli K-12
intracellular organelle30S ribosomal protein S16Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S16Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S16Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S16Escherichia coli K-12
cytosol30S ribosomal protein S18Escherichia coli K-12
ribosome30S ribosomal protein S18Escherichia coli K-12
cytoplasm30S ribosomal protein S18Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S18Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S18Escherichia coli K-12
cytoplasm30S ribosomal protein S19Escherichia coli K-12
cytosol30S ribosomal protein S19Escherichia coli K-12
ribosome30S ribosomal protein S19Escherichia coli K-12
intracellular organelle30S ribosomal protein S19Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S19Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S19Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S19Escherichia coli K-12
cytosol30S ribosomal protein S20Escherichia coli K-12
ribosome30S ribosomal protein S20Escherichia coli K-12
cytoplasm30S ribosomal protein S20Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S20Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S20Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S20Escherichia coli K-12
cytosol30S ribosomal protein S20Escherichia coli K-12
ribosome30S ribosomal protein S2Escherichia coli K-12
cytoplasm30S ribosomal protein S2Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S2Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S2Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S2Escherichia coli K-12
cytosol30S ribosomal protein S3Escherichia coli K-12
ribosome30S ribosomal protein S3Escherichia coli K-12
cytoplasm30S ribosomal protein S3Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S3Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S3Escherichia coli K-12
cytosol30S ribosomal protein S4Escherichia coli K-12
ribosome30S ribosomal protein S4Escherichia coli K-12
cytoplasm30S ribosomal protein S4Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S4Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S4Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S4Escherichia coli K-12
cytoplasm30S ribosomal protein S5Escherichia coli K-12
cytosol30S ribosomal protein S5Escherichia coli K-12
ribosome30S ribosomal protein S5Escherichia coli K-12
intracellular organelle30S ribosomal protein S5Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S5Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S5Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S5Escherichia coli K-12
cytoplasm30S ribosomal protein S8Escherichia coli K-12
cytosol30S ribosomal protein S8Escherichia coli K-12
ribosome30S ribosomal protein S8Escherichia coli K-12
intracellular organelle30S ribosomal protein S8Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S8Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S8Escherichia coli K-12
cytosol30S ribosomal protein S9Escherichia coli K-12
ribosome30S ribosomal protein S9Escherichia coli K-12
intracellular organelle30S ribosomal protein S9Escherichia coli K-12
cytoplasm30S ribosomal protein S9Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S9Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S9Escherichia coli K-12
cytoplasm50S ribosomal protein L13Escherichia coli K-12
cytosol50S ribosomal protein L13Escherichia coli K-12
ribosome50S ribosomal protein L13Escherichia coli K-12
intracellular organelle50S ribosomal protein L13Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L13Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L13Escherichia coli K-12
ribosome50S ribosomal protein L13Escherichia coli K-12
cytosol50S ribosomal protein L14Escherichia coli K-12
ribosome50S ribosomal protein L14Escherichia coli K-12
cytoplasm50S ribosomal protein L14Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L14Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L14Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L14Escherichia coli K-12
ribosome50S ribosomal protein L16Escherichia coli K-12
cytoplasm50S ribosomal protein L16Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L16Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L16Escherichia coli K-12
ribosome50S ribosomal protein L23Escherichia coli K-12
cytoplasm50S ribosomal protein L23Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L23Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L23Escherichia coli K-12
cytoplasm30S ribosomal protein S15Escherichia coli K-12
cytosol30S ribosomal protein S15Escherichia coli K-12
ribosome30S ribosomal protein S15Escherichia coli K-12
intracellular organelle30S ribosomal protein S15Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S15Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S15Escherichia coli K-12
cytosol50S ribosomal protein L17Escherichia coli K-12
ribosome50S ribosomal protein L17Escherichia coli K-12
cytoplasm50S ribosomal protein L17Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L17Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L17Escherichia coli K-12
cytoplasm50S ribosomal protein L21Escherichia coli K-12
cytosol50S ribosomal protein L21Escherichia coli K-12
ribosome50S ribosomal protein L21Escherichia coli K-12
intracellular organelle50S ribosomal protein L21Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L21Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L21Escherichia coli K-12
ribosome50S ribosomal protein L30Escherichia coli K-12
cytoplasm50S ribosomal protein L30Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L30Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L30Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L30Escherichia coli K-12
cytosol50S ribosomal protein L6Escherichia coli K-12
ribosome50S ribosomal protein L6Escherichia coli K-12
cytoplasm50S ribosomal protein L6Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L6Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L6Escherichia coli K-12
cytoplasm30S ribosomal protein S14Escherichia coli K-12
ribosome30S ribosomal protein S14Escherichia coli K-12
intracellular organelle30S ribosomal protein S14Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S14Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S14Escherichia coli K-12
small ribosomal subunit30S ribosomal protein S14Escherichia coli K-12
ribosome30S ribosomal protein S17Escherichia coli K-12
cytoplasm30S ribosomal protein S17Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S17Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S17Escherichia coli K-12
cytoplasm30S ribosomal protein S1Escherichia coli K-12
ribosome30S ribosomal protein S1Escherichia coli K-12
membrane30S ribosomal protein S1Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S1Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S1Escherichia coli K-12
cytoplasm50S ribosomal protein L18Escherichia coli K-12
cytosol50S ribosomal protein L18Escherichia coli K-12
ribosome50S ribosomal protein L18Escherichia coli K-12
intracellular organelle50S ribosomal protein L18Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L18Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L18Escherichia coli K-12
cytosol50S ribosomal protein L2Escherichia coli K-12
ribosome50S ribosomal protein L2Escherichia coli K-12
cytoplasm50S ribosomal protein L2Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L2Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L2Escherichia coli K-12
DnaA-L2 complex50S ribosomal protein L2Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L2Escherichia coli K-12
cytosol50S ribosomal protein L3Escherichia coli K-12
ribosome50S ribosomal protein L3Escherichia coli K-12
cytoplasm50S ribosomal protein L3Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L3Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L3Escherichia coli K-12
cytosol50S ribosomal protein L24Escherichia coli K-12
ribosome50S ribosomal protein L24Escherichia coli K-12
cytoplasm50S ribosomal protein L24Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L24Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L24Escherichia coli K-12
cytosol50S ribosomal protein L4Escherichia coli K-12
ribosome50S ribosomal protein L4Escherichia coli K-12
cytoplasm50S ribosomal protein L4Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L4Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L4Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L4Escherichia coli K-12
cytosol50S ribosomal protein L22Escherichia coli K-12
ribosome50S ribosomal protein L22Escherichia coli K-12
cytoplasm50S ribosomal protein L22Escherichia coli K-12
large ribosomal subunit50S ribosomal protein L22Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L22Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L22Escherichia coli K-12
cytosol50S ribosomal protein L5Escherichia coli K-12
ribosome50S ribosomal protein L5Escherichia coli K-12
cytoplasm50S ribosomal protein L5Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L5Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L5Escherichia coli K-12
cytosol30S ribosomal protein S21Escherichia coli K-12
ribosome30S ribosomal protein S21Escherichia coli K-12
cytoplasm30S ribosomal protein S21Escherichia coli K-12
cytosolic small ribosomal subunit30S ribosomal protein S21Escherichia coli K-12
ribonucleoprotein complex30S ribosomal protein S21Escherichia coli K-12
cytosol50S ribosomal protein L25Escherichia coli K-12
ribosome50S ribosomal protein L25Escherichia coli K-12
cytoplasm50S ribosomal protein L25Escherichia coli K-12
cytosolic large ribosomal subunit50S ribosomal protein L25Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L25Escherichia coli K-12
ribosome50S ribosomal protein L36 2Escherichia coli K-12
cytosolic ribosome50S ribosomal protein L36 2Escherichia coli K-12
ribonucleoprotein complex50S ribosomal protein L36 2Escherichia coli K-12
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (46)

Assay IDTitleYearJournalArticle
AID1346987P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347160Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1296008Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening2020SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1347159Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay2020Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1346986P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen2019Molecular pharmacology, 11, Volume: 96, Issue:5
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1497310Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 1 after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694451Antibacterial activity against Staphylococcus aureus NE1416 Tn mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694436Binding affinity to Staphylococcus aureus 70S ribosome assessed as dissociation constant by measuring reduction in BODIPY-Erythromycin A binding incubated for 1.5 hr by fluorescence polarization assay2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1497307Antibacterial activity against methicillin-sensitive Staphylococcus aureus UAMS-1 after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694450Antibacterial activity against Staphylococcus aureus NE939 Tn mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694439Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as Vmax for DP-G1cNAc to EU- DP-G1cNAc conversion at 100 uM preincubated for 15 mins by HPLC method (Rvb = 0.235 +/- 0.049 uM/min)2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1675618Antibacterial activity against vancomycin-resistant Staphylococcus aureus2020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
Synthesis and biological evaluation of semi-synthetic albocycline analogs.
AID1497315Inhibition of GST-tagged Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) cells preincubated with PEP and enzyme for 10 mins followed by UDP-GlcNAc addition measured after 3 hrs by HPLC analysis2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1675625Antibacterial activity against methicillin sensitive Staphylococcus aureus UAMS12020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
Synthesis and biological evaluation of semi-synthetic albocycline analogs.
AID1694456Synergistic antibacterial activity against Staphylococcus aureus UAMS-1 AlbR D resistant mutant assessed as fractional inhibitory concentration index in presence of fosfomycin by broth microdilution assay2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694440Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as Vmax for DP-G1cNAc to EU- DP-G1cNAc conversion at 150 uM preincubated for 15 mins by HPLC method (Rvb = 0.235 +/- 0.049 uM/min)2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1497312Cytotoxicity against human HepG2 cells at <= 64 ug/ml by MTT assay2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1497311Antibacterial activity against vancomycin-resistant Staphylococcus aureus isolate 10 after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1497317Inhibition of GST-tagged Escherichia coli MurA expressed in Escherichia coli BL21(DE3) cells preincubated with PEP and enzyme for 10 mins followed by UDP-GlcNAc addition measured after 3 hrs by HPLC analysis2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1497309Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694455Synergistic antibacterial activity against Staphylococcus aureus UAMS-1 AlbR C resistant mutant assessed as fractional inhibitory concentration index in presence of fosfomycin by broth microdilution assay2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694442Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as Kcat for DP-G1cNAc to EU- DP-G1cNAc conversion at 100 uM preincubated for 15 mins by HPLC method (Rvb = 0.471 +/- 0.994 /min)2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1497305Antibacterial activity against Staphylococcus aureus ATCC 25923 after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1497316Inhibition of GST-tagged Staphylococcus aureus MurZ expressed in Escherichia coli BL21(DE3) cells preincubated with PEP and enzyme for 10 mins followed by UDP-GlcNAc addition measured after 3 hrs by HPLC analysis2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694453Synergistic antibacterial activity against Staphylococcus aureus UAMS-1 AlbR A resistant mutant assessed as fractional inhibitory concentration index in presence of fosfomycin by broth microdilution assay2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1497313Inhibition of GST-tagged Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) cells assessed as reduction in EP-UDP-GlcNAc production at 650 uM preincubated with UDP-GlcNAc and enzyme for 10 mins followed by PEP addition measured after 3 hrs2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694448Antibacterial activity against Staphylococcus aureus UAMS-1 AlbR D resistant mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1675624Antibacterial activity against methicillin resistant Staphylococcus aureus USA3002020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
Synthesis and biological evaluation of semi-synthetic albocycline analogs.
AID1497314Inhibition of GST-tagged Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) cells assessed as reduction in EP-UDP-GlcNAc production at 650 uM preincubated with PEP and enzyme for 10 mins followed by UDP-GlcNAc addition measured after 3 hrs2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694449Antibacterial activity against Staphylococcus aureus USA300 Tn mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694438Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as Vmax for DP-G1cNAc to EU- DP-G1cNAc conversion at 50 uM preincubated for 15 mins by HPLC method (Rvb = 0.235 +/- 0.049 uM/min)2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694441Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as Kcat for DP-G1cNAc to EU- DP-G1cNAc conversion at 50 uM preincubated for 15 mins by HPLC method (Rvb = 0.471 +/- 0.994 /min)2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1675619Antibacterial activity against vancomycin-intermediate Staphylococcus aureus2020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
Synthesis and biological evaluation of semi-synthetic albocycline analogs.
AID1497306Antibacterial activity against Escherichia coli RFM795 harboring lptD gene mutant after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1497318Antibacterial activity against methicillin-resistant Staphylococcus aureus2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694446Antibacterial activity against Staphylococcus aureus UAMS-1 AlbR B resistant mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694457Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as using DP-G1cNAc as substrate preincubated for 15 mins by HPLC method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694452Synergistic antibacterial activity against Staphylococcus aureus UAMS-1 assessed as fractional inhibitory concentration index in presence of fosfomycin by broth microdilution assay2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1497308Antibacterial activity against methicillin-resistant Staphylococcus aureus LAC JE2 after 16 hrs by broth micro dilution method2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1497319Inhibition of Staphylococcus aureus MurA assessed as reduction in [3H]GlcNAc uptake2018Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus.
AID1694445Antibacterial activity against Staphylococcus aureus UAMS-1 AlbR A resistant mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1675620Antibacterial activity against methicillin resistant Staphylococcus aureus2020Bioorganic & medicinal chemistry letters, 11-01, Volume: 30, Issue:21
Synthesis and biological evaluation of semi-synthetic albocycline analogs.
AID1694443Inhibition of Staphylococcus aureus MurA expressed in Escherichia coli BL21(DE3) assessed as Kcat for DP-G1cNAc to EU- DP-G1cNAc conversion at 150 uM preincubated for 15 mins by HPLC method (Rvb = 0.471 +/- 0.994 /min)2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694444Antibacterial activity against Staphylococcus aureus UAMS-1 assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694454Synergistic antibacterial activity against Staphylococcus aureus UAMS-1 AlbR B resistant mutant assessed as fractional inhibitory concentration index in presence of fosfomycin by broth microdilution assay2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
AID1694447Antibacterial activity against Staphylococcus aureus UAMS-1 AlbR C resistant mutant assessed as growth inhibition incubated at 16 to 24 hrs by CLSI method2021Bioorganic & medicinal chemistry, 02-15, Volume: 32Staphylococcus aureus resistance to albocycline can be achieved by mutations that alter cellular NAD/PH pools.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (14.29)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's5 (35.71)24.3611
2020's4 (28.57)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.05 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.46 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
vancomycin
Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.		2.1710glycopeptideantibacterial drug;
antimicrobial agent;
bacterial metabolite
glycidyl nitrate
glycidyl nitrate: a nitric oxide donor; structure in first source. peptidoglycan : A peptidoglycosaminoglycan formed by alternating residues of beta-(1->4)-linked N-acetylglucosamine and N-acetylmuramic acid {2-amino-3-O-[(S)-1-carboxyethyl]-2-deoxy-D-glucose} residues. Attached to the carboxy group of the muramic acid is a peptide chain of three to five amino acids.		2.1710
fosfomycin
Fosfomycin: An antibiotic produced by Streptomyces fradiae.. fosfomycin : A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus.		2.6320epoxide;
phosphonic acids		antimicrobial agent;
EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor
nadp
[no description available]		2.3110
carbomycin
carbomycin: from Streptomyces halstedii		6.9910
cem 101
solithromycin: an antibacterial fluoroketolide; structure in first source		2.3110
ConditionIndicatedRelationship StrengthStudiesTrials
Congenital Zika Syndrome
[description not available]		02.2510
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		02.2510
Zika Virus Infection
A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.		02.2510
B16 Melanoma
[description not available]		01.9910