| Assay ID | Title | Year | Journal | Article |
|---|
| AID4876 | The binding affinity was measured on 5-hydroxytryptamine 1D receptor using [3H]- serotonin as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID4767 | The binding affinity was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID221935 | The binding affinity was measured on glycine receptor using [3H]- strychnine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID219805 | The binding affinity was measured on alpha-2-adrenergic receptor using [3H]- clonidine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID50508 | The binding affinity was measured on cholecystokinin type A receptor using [3H]- CCK-8 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID61649 | The binding affinity was measured on dopamine receptor D1 using [3H]- dopamine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID221936 | The binding affinity was measured on glycine strych. ins receptor using [3H]- 5,7-diClkyn.acid as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID146872 | The binding affinity was measured on Na+2(BTX)brain receptor using [3H]- batrachotox as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID6424 | The binding affinity was measured on 5-hydroxytryptamine receptor uptake receptor using [3H]- paroxetine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID5304 | The binding affinity was measured on 5-hydroxytryptamine 2 receptor using [3H]- spiperone as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID47563 | Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of rat brain | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID143098 | The binding affinity was measured on NMDA receptor using [3H]- CGS-19755 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID197156 | The pA2 is the negative logarithm of the molar concentration of an antagonist which necessitates the doubling of the agonist dose to couteract the effect of that antagonist and restore the original response was measured in rat isolated vagus nerve test. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID3202 | The binding affinity was measured on 5-hydroxytryptamine 4 receptor using [3H]- GR-113808 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID222169 | The binding affinity was measured on melatonin receptor using [3H]- 2-iodo-melat as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID51469 | The binding affinity was measured on cholecystokinin type B receptor using [3H]- CCK-8 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID210172 | The binding affinity was measured on TRH receptor using [3H]- MeTRH as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID221171 | The binding affinity was measured on leukotriene-D4 receptor using [3H]- LTD4 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID5902 | Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID225226 | The binding affinity was measured on muscarine M3 receptor using [3H]- N-Me-SCOPOL as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID228446 | The binding affinity was measured on tryptamine receptor using [3H]- tryptamine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID87533 | The binding affinity was measured on histamine H1 receptor using [3H]- mepyramine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID221170 | The binding affinity was measured on leukotriene-6 receptor using [3H]- IL-6 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID104027 | The binding affinity was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID218722 | The binding affinity was measured on beta-1,2-adrenergic receptor using [3H]- DHA as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID152095 | The binding affinity was measured on substance P as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID229206 | The binding affinity was measured on sigma receptor using [3H]- (+)-3-PPP as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID173594 | Dose of antagonist which inhibits the by the 2-Me-5-HT induced slowing of the heart rate by 10 beats/5 s. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID5908 | The binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID65752 | The binding affinity was measured on dopamine receptor D3 using [3H]- dopamine as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID223592 | The binding affinity was measured on kappa-opiate receptor using [3H]- EKC as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID224719 | The binding affinity was measured on mu-opiate receptor using [3H]- naloxone as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID101705 | The binding affinity was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID65903 | The binding affinity was measured on dopamine receptor D2 using [3H]- spiperone as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID72139 | Displacement of [3H]DH-muscimol from rat GABA-A receptor | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID220521 | The binding affinity was measured on delta-opiate receptor using [3H]- dadle as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID197155 | The pA2 is the negative logarithm of the molar concentration of an antagonist which necessitates the doubling of the agonist dose to couteract the effect of that antagonist and restore the original response was measured in guinea pig isolated ileu m test. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID47564 | Inhibition of [3H]D-888 binding to L-type calcium channel verapamil site of rat brain | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID4352 | The binding affinity was measured on 5-hydroxytryptamine 1A receptor using [3H]- 8-OH-DPAT as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID91719 | The binding affinity was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID184810 | Lowest effective dose affecting behavioral parameter in at least half of the animals. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID40505 | Displacement of [3H]- Diazepam from rat GABA-A benzodiazepine receptor | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID4703 | The binding affinity was measured on 5-hydroxytryptamine 1B receptor using [3H]- serotonin as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| AID89720 | The binding affinity was measured on histamine H3 receptor using [3H]- N-Me-histam as radioligand. | 1993 | Journal of medicinal chemistry, Nov-12, Volume: 36, Issue:23
| Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |