| Assay ID | Title | Year | Journal | Article |
|---|
| AID730431 | Agonist activity at CMX-GAL4 tagged human VDR expressed in HEK293 cells assessed as increase in transcriptional activity by luciferase reporter gene assay | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID1266902 | Toxicity in rat assessed as hypercalcemic activity at 30 mg/kg/day administered for 7 days | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID255943 | Androgen antagonistic activity as inhibitory concentration against testosterone-induced SC-3 cell proliferation | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19
| Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities. |
| AID1266895 | Antipoliferative activity against human PC3 cells after 48 hrs by MTT assay | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID1266899 | Cytotoxicity against human L02 cells after 48 hrs by MTT assay | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID1266898 | Antipoliferative activity against human HepG2 cells after 48 hrs by MTT assay | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID256061 | Activity ratio of effective dose against vitamin D3 and inhibitory activity against androgen antagonistic activity | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19
| Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities. |
| AID730421 | Agonist activity at human androgen receptor expressed in HEK293 cells assessed as increase in transcriptional activity in presence of 0.3 nM testosterone by luciferase and beta-galactosidase reporter gene assay | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID730430 | Agonist activity at VDR (unknown origin) by reporter gene assay | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID730425 | Selectivity index, ratio of agonist PC50 for CMX-GAL4 tagged human VDR to antagonist IC50 for human androgen receptor | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID254447 | Binding affinity to androgen receptor by incubation with GST-hARLBD and [3H]testosterone; ND = not detected | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19
| Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities. |
| AID255683 | Vitamin D3 agonistic activity as effective dose for HL-60 monocytic cell differentiation | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19
| Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities. |
| AID730429 | Growth inhibition of human LNCAP cells | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID730428 | Induction of monocytic cell differentiation in human HL60 cells | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID730426 | Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity at 10 uM by luciferase and beta-galactosidase reporter gene assay | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID1266896 | Antipoliferative activity against human MCF7 cells after 48 hrs by MTT assay | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID1266897 | Antipoliferative activity against human Caco2 cells after 48 hrs by MTT assay | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID1266894 | Agonist activity at vitamin D3 receptor in human HL-60 cells assessed as induction of cell differentiation after 96 hrs by NBT dye-based microscopic analysis | 2016 | European journal of medicinal chemistry, Jan-01, Volume: 107 | Novel nonsecosteroidal VDR ligands with phenyl-pyrrolyl pentane skeleton for cancer therapy. |
| AID730427 | Antagonist activity at human androgen receptor expressed in HEK293 cells assessed as inhibition of transcriptional activity by luciferase and beta-galactosidase reporter gene assay | 2013 | Bioorganic & medicinal chemistry, Apr-01, Volume: 21, Issue:7
| Development of silicon-containing bis-phenol derivatives as androgen receptor antagonists: selectivity switching by C/Si exchange. |
| AID1799452 | VDR Ligand-Binding Assay from Article 10.1016/S1074-5521(99)80072-6: \\Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3.\\ | 1999 | Chemistry & biology, May, Volume: 6, Issue:5
| Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3. |
| AID1799453 | DBP Binding Assay from Article 10.1016/S1074-5521(99)80072-6: \\Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3.\\ | 1999 | Chemistry & biology, May, Volume: 6, Issue:5
| Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |