| Assay ID | Title | Year | Journal | Article |
|---|
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID293967 | Antiinflammatory activity against carrageenan-induced paw edema in Wistar rat at 300 umol/kg, po after 3 hrs | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| AID436513 | Inhibition of PDE4B up to 30 uM | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10
| Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives. |
| AID565895 | Activity of human recombinant CYP1A2 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID436503 | Vasorelaxant activity in endothelium-intact Wistar rat thoracic aortic ring assessed as inhibition of phenylephrine-induced contraction | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10
| Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives. |
| AID565900 | Activity of human recombinant CYP2D6 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID565897 | Activity of human recombinant CYP2C8 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID565902 | Activity of human recombinant CYP3A5 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID293969 | Antiinflammatory activity against TPA-induced ear edema in Swiss mouse at 300 umol/kg, po after 6 hrs | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| AID293971 | Antihyperalgesic effect against formalin-induced pain in mouse at 100 umol/kg, po assessed as licking activity in neurogenic phase | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| AID565898 | Activity of human recombinant CYP2C9 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID436508 | Vasorelaxant activity in endothelium-denuded Wistar rat thoracic aortic ring assessed as inhibition of phenylephrine-induced contraction at 100 uM | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10
| Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives. |
| AID565899 | Activity of human recombinant CYP2C19 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID1397215 | Vasodilatory activity in Wistar rat thoracic aortic rings assessed as inhibition of noradrenaline-induced contraction | 2018 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 28, Issue:17
| N-Acylhydrazones as drugs. |
| AID436506 | Vasorelaxant activity in endothelium-denuded Wistar rat thoracic aortic ring assessed as inhibition of phenylephrine-induced contraction | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10
| Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives. |
| AID436514 | Inhibition of PDE5 up to 30 uM | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10
| Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives. |
| AID293974 | Displacement of [3H]SR141716A from CB1 cannabinoid receptor in Swiss mouse brain homogenate | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| AID293972 | Antihyperalgesic effect against formalin-induced pain in mouse at 100 umol/kg, po assessed as licking activity in inflammatory phase | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| AID565901 | Activity of human recombinant CYP3A4 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID436512 | Inhibition of PDE2A up to 30 uM | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10
| Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives. |
| AID293970 | Antiinflammatory activity against AA-induced ear edema in Swiss mouse at 300 umol/kg, po after 1 hr | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| AID565896 | Activity of human recombinant CYP2B6 assessed as compound remaining | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1
| CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. |
| AID368205 | Antiinflammatory activity in Wistar rat assessed as inhibition of carrageenan-induced paw edema volume at 300 umol/kg, po administered 1 hrs prior to carrageenan challenge measured after 3 hrs | 2009 | Bioorganic & medicinal chemistry, Feb-01, Volume: 17, Issue:3
| Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates. |
| AID293968 | Antiinflammatory activity against carrageenan-induced paw edema in Wistar rat | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6
| Synthesis, pharmacological evaluation and electrochemical studies of novel 6-nitro-3,4-methylenedioxyphenyl-N-acylhydrazone derivatives: Discovery of LASSBio-881, a new ligand of cannabinoid receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |