| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| choline | [no description available] | medium | 1 | 0 | cholines | allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite |
| dibenzofuran | [no description available] | medium | 1 | 0 | dibenzofurans;
mancude organic heterotricyclic parent;
polycyclic heteroarene | xenobiotic |
| imidazole | [no description available] | medium | 1 | 0 | imidazole | |
| bw 284 c 51 | [no description available] | medium | 1 | 0 | | |
| 1-methylimidazole | [no description available] | medium | 1 | 0 | imidazoles | |
| tacrine | [no description available] | medium | 1 | 0 | acridines;
aromatic amine | EC 3.1.1.7 (acetylcholinesterase) inhibitor |
| pentamidine | [no description available] | medium | 1 | 0 | aromatic ether;
carboxamidine;
diether | anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic |
| physostigmine | [no description available] | medium | 1 | 0 | carbamate ester;
indole alkaloid | antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic |
| neostigmine bromide | [no description available] | medium | 1 | 0 | bromide salt | |
| edrophonium bromide | [no description available] | medium | 1 | 0 | | |
| azomycin | [no description available] | medium | 1 | 0 | C-nitro compound;
imidazoles | antitubercular agent |
| 2-methylimidazole | [no description available] | medium | 1 | 0 | | |
| chlormequat | [no description available] | medium | 1 | 0 | quaternary ammonium ion | plant growth retardant |
| 3-hydroxyphenyltrimethylammonium | [no description available] | medium | 1 | 0 | | |
| 1-methyl-2-nitroimidazole | [no description available] | medium | 1 | 0 | | |
| 2,3,7,8-tetrachlorodibenzodioxine | [no description available] | medium | 1 | 0 | polychlorinated dibenzodioxine | |
| butyrylcholine | [no description available] | medium | 1 | 0 | acylcholine | |
| octachlorodibenzo-4-dioxin | [no description available] | medium | 1 | 0 | polychlorinated dibenzodioxine | |
| butyrylthiocholine | [no description available] | medium | 1 | 0 | quaternary ammonium ion | |
| 2-chlorodibenzofuran | [no description available] | medium | 1 | 0 | | |
| 1,2,3,4-tetrachlorodibenzodioxin | [no description available] | medium | 1 | 0 | polychlorinated dibenzodioxine | |
| pcb 118 | [no description available] | medium | 1 | 0 | dichlorobenzene;
pentachlorobiphenyl;
trichlorobenzene | |
| 3,4,3',4'-tetrachlorobiphenyl | [no description available] | medium | 20 | 0 | dichlorobenzene;
tetrachlorobiphenyl | |
| 2,3,3',4,4'-pentachlorobiphenyl | [no description available] | medium | 1 | 0 | dichlorobenzene;
pentachlorobiphenyl;
trichlorobenzene | |
| 2,3,4,5-tetrachlorobiphenyl | [no description available] | medium | 1 | 0 | tetrachlorobenzene;
tetrachlorobiphenyl | |
| 1,2,7,8-tetrachlorodibenzo-p-dioxin | [no description available] | medium | 1 | 0 | | |
| 2,4,5,2',4',5'-hexachlorobiphenyl | [no description available] | medium | 3 | 0 | hexachlorobiphenyl | |
| thiocholine | [no description available] | medium | 1 | 0 | | |
| 2,3,3',4,4',5-hexachlorobiphenyl | [no description available] | medium | 1 | 0 | dichlorobenzene;
hexachlorobiphenyl;
tetrachlorobenzene | |
| 2,8-dichlorodibenzo-4-dioxin | [no description available] | medium | 1 | 0 | | |
| 1,2,3,4,7,8-hexachlorodibenzodioxin | [no description available] | medium | 1 | 0 | polychlorinated dibenzodioxine | |
| 1,2,4-trichlorodibenzo-1,4-dioxin | [no description available] | medium | 1 | 0 | | |
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin | [no description available] | medium | 1 | 0 | polychlorinated dibenzodioxine | |
| 2,3,7,8-tetrabromodibenzo-4-dioxin | [no description available] | medium | 1 | 0 | dibenzodioxine;
organobromine compound | |
| 2,3,7,8-tetrachlorodibenzofuran | [no description available] | medium | 1 | 0 | polychlorinated dibenzofuran | |
| 2,3,4,7,8-pentachlorodibenzofuran | [no description available] | medium | 1 | 0 | polychlorinated dibenzofuran | |
| 1,2,3,7,8-pentachlorodibenzofuran | [no description available] | medium | 1 | 0 | polychlorinated dibenzofuran | |
| 1,2,3,4,7,8-hexachlorodibenzofuran | [no description available] | medium | 1 | 0 | polychlorinated dibenzofuran | |
| 2,3,4,4'5-pentachlorobiphenyl | [no description available] | medium | 1 | 0 | monochlorobenzenes;
pentachlorobiphenyl;
tetrachlorobenzene | |
| 1,3-di-(4-imidazolino-2-methoxyphenoxy)propane | [no description available] | medium | 1 | 0 | | |
| 3,4,5,3',4'-pentachlorobiphenyl | [no description available] | medium | 4 | 0 | pentachlorobiphenyl;
trichlorobenzene | |
| propamidine | [no description available] | medium | 1 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
| norharman | [no description available] | medium | 1 | 0 | beta-carbolines;
mancude organic heterotricyclic parent | fungal metabolite;
marine metabolite |
| hexamidine | [no description available] | medium | 1 | 0 | aromatic ether;
guanidines;
polyether | antimicrobial agent;
antiseptic drug |
| 2-ethylimidazole | [no description available] | medium | 1 | 0 | | |
| 2-phenylimidazole | [no description available] | medium | 1 | 0 | | |
| 2-aminoimidazole | [no description available] | medium | 1 | 0 | | |
| hexyltrimethylammonium | [no description available] | medium | 1 | 0 | | |
| trimethyl(4-oxopentyl)ammonium | [no description available] | medium | 1 | 0 | quaternary ammonium ion | |
| 2,5-dihydro-2-(4-methoxyphenyl)-3h-pyrazolo(4,3-c)quinolin-3-one | [no description available] | medium | 1 | 0 | | |
| beta-carboline-3-carboxylic acid ethyl ester | [no description available] | medium | 1 | 0 | beta-carbolines | |
| beta-carboline-3-carboxylic acid methyl ester | [no description available] | medium | 1 | 0 | beta-carbolines | |
| 1,3-di(4-imidazolinophenoxyl)propane | [no description available] | medium | 1 | 0 | | |
| 3-ethoxy-beta-carboline | [no description available] | medium | 1 | 0 | | |
| tert-butyl beta-carboline-3-carboxylate | [no description available] | medium | 1 | 0 | | |
| butamidine | [no description available] | medium | 1 | 0 | | |
| 3-chlorodibenzofuran | [no description available] | medium | 1 | 0 | | |
| 1-(4-hydroxybenzyl)imidazole-2-thiol | [no description available] | medium | 1 | 0 | | |
| 3-propoxy-beta-carboline | [no description available] | medium | 1 | 0 | | |
| harman | [no description available] | medium | 1 | 0 | harmala alkaloid;
indole alkaloid fundamental parent;
indole alkaloid | anti-HIV agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
plant metabolite |
| 1-Ethyl-9H-pyrido[3,4-b]indole | [no description available] | medium | 1 | 0 | harmala alkaloid | |
| sk&f 102698 | [no description available] | medium | 1 | 0 | | |
| chlordecone | [no description available] | medium | 1 | 0 | cyclic ketone;
organochlorine compound | insecticide;
persistent organic pollutant |
| hexachlorocyclohexane | [no description available] | medium | 1 | 0 | chlorocyclohexane | |
| vanillin | [no description available] | medium | 1 | 0 | benzaldehydes;
monomethoxybenzene;
phenols | anti-inflammatory agent;
anticonvulsant;
antioxidant;
flavouring agent;
plant metabolite |
| 2,4,5-trichlorophenoxyacetic acid | [no description available] | medium | 1 | 0 | chlorophenoxyacetic acid;
trichlorobenzene | defoliant;
phenoxy herbicide;
synthetic auxin |
| 4-nonylphenol | [no description available] | medium | 1 | 0 | phenols | environmental contaminant |
| clomiphene | [no description available] | medium | 1 | 0 | tertiary amine | estrogen antagonist;
estrogen receptor modulator |
| dichlorodiphenyl dichloroethylene | [no description available] | medium | 1 | 0 | chlorophenylethylene;
monochlorobenzenes | human xenobiotic metabolite;
persistent organic pollutant |
| ddt | [no description available] | medium | 1 | 0 | benzenoid aromatic compound;
chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide | bridged diphenyl acaricide;
carcinogenic agent;
endocrine disruptor;
persistent organic pollutant |
| benzophenone | [no description available] | medium | 1 | 0 | benzophenones | photosensitizing agent;
plant metabolite |
| endosulfan | [no description available] | medium | 1 | 0 | cyclic sulfite ester;
cyclodiene organochlorine insecticide | acaricide;
agrochemical;
GABA-gated chloride channel antagonist;
persistent organic pollutant |
| heptachlor | [no description available] | medium | 1 | 0 | cyclodiene organochlorine insecticide | agrochemical;
antibacterial agent;
antifungal agent;
GABA-gated chloride channel antagonist;
persistent organic pollutant |
| methoxychlor | [no description available] | medium | 1 | 0 | organochlorine insecticide | |
| nafoxidine | [no description available] | medium | 1 | 0 | benzenes;
naphthalenes;
ring assembly | |
| corticosterone | [no description available] | medium | 1 | 0 | 11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite |
| prednisolone | [no description available] | medium | 1 | 0 | 11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic |
| estriol | [no description available] | medium | 1 | 0 | 16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid | estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite |
| spironolactone | [no description available] | medium | 1 | 0 | 3-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester | aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic |
| aldosterone | [no description available] | medium | 1 | 0 | 11beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde | human metabolite;
mouse metabolite |
| androsterone | [no description available] | medium | 1 | 0 | 17-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid | androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone |
| 17-desoxyestradiol | [no description available] | medium | 1 | 0 | 3-hydroxy steroid;
phenolic steroid;
phenols | estrogen |
| ethinyl estradiol | [no description available] | medium | 1 | 0 | 17-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound | xenoestrogen |
| chlordan | [no description available] | medium | 1 | 0 | cyclodiene organochlorine insecticide | GABA-gated chloride channel antagonist;
persistent organic pollutant |
| testosterone propionate | [no description available] | medium | 1 | 0 | steroid ester | |
| methyltestosterone | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
enone | anabolic agent;
androgen;
antineoplastic agent |
| androstenedione | [no description available] | medium | 1 | 0 | 17-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid | androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite |
| norethindrone | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound;
tertiary alcohol | progestin;
synthetic oral contraceptive |
| norethynodrel | [no description available] | medium | 1 | 0 | oxo steroid | |
| medroxyprogesterone acetate | [no description available] | medium | 1 | 0 | 20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester | adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive |
| dichlorodiphenyldichloroethane | [no description available] | medium | 1 | 0 | chlorophenylethane;
monochlorobenzenes;
organochlorine insecticide | xenobiotic metabolite |
| bisphenol a | [no description available] | medium | 1 | 0 | bisphenol | endocrine disruptor;
environmental contaminant;
xenobiotic;
xenoestrogen |
| p-tert-amylphenol | [no description available] | medium | 1 | 0 | alkylbenzene | |
| 2-sec-butylphenol | [no description available] | medium | 1 | 0 | phenols | |
| 4-phenylphenol | [no description available] | medium | 1 | 0 | hydroxybiphenyls | |
| propylparaben | [no description available] | medium | 1 | 0 | benzoate ester;
paraben;
phenols | antifungal agent;
antimicrobial agent |
| butylphen | [no description available] | medium | 1 | 0 | phenols | allergen |
| methylparaben | [no description available] | medium | 1 | 0 | paraben | antifungal agent;
antimicrobial food preservative;
neuroprotective agent;
plant metabolite |
| monobenzone | [no description available] | medium | 1 | 0 | benzyl ether | allergen;
dermatologic drug;
melanin synthesis inhibitor |
| 3-chlorophenol | [no description available] | medium | 1 | 0 | monochlorophenol | |
| 2,4-dihydroxybenzophenone | [no description available] | medium | 1 | 0 | benzophenones | |
| cyproterone acetate | [no description available] | medium | 1 | 0 | 20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester | androgen antagonist;
geroprotector;
progestin |
| epitestosterone | [no description available] | medium | 1 | 0 | 17alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid | androgen antagonist;
human metabolite |
| flavanone | [no description available] | medium | 1 | 0 | flavanones | |
| androstenediol | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid | androgen;
human metabolite;
mouse metabolite;
radiation protective agent |
| dihydrotestosterone | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid | androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite |
| flavone | [no description available] | medium | 1 | 0 | flavones | metabolite;
nematicide |
| 4-cumylphenol | [no description available] | medium | 1 | 0 | diarylmethane | |
| o,p'-ddt | [no description available] | medium | 1 | 0 | diarylmethane | |
| 4-hydroxybenzophenone | [no description available] | medium | 1 | 0 | benzophenones | |
| 4-chloro-2-cresol | [no description available] | medium | 1 | 0 | monochlorobenzenes;
phenols | |
| 4-octylphenol | [no description available] | medium | 1 | 0 | phenols | metabolite;
surfactant;
xenoestrogen |
| ac 45594 | [no description available] | medium | 1 | 0 | aromatic ether | |
| promegestone | [no description available] | medium | 1 | 0 | 20-oxo steroid;
3-oxo-Delta(4) steroid | antineoplastic agent;
progesterone receptor agonist;
progestin |
| 2,4'-dichlorobiphenyl | [no description available] | medium | 1 | 0 | dichlorobiphenyl;
monochlorobenzenes | |
| 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol | [no description available] | medium | 1 | 0 | stilbenoid | |
| taleranol | [no description available] | medium | 1 | 0 | macrolide | |
| bisphenol b | [no description available] | medium | 1 | 0 | bisphenol | |
| alfatradiol | [no description available] | medium | 1 | 0 | 17alpha-hydroxy steroid;
3-hydroxy steroid;
estradiol | estrogen;
geroprotector |
| 4,4'-Dihydroxybenzophenone | [no description available] | medium | 1 | 0 | benzophenones | |
| 6-hydroxyflavone | [no description available] | medium | 1 | 0 | hydroxyflavonoid | |
| 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane | [no description available] | medium | 1 | 0 | bisphenol | |
| 1,1-Dichloro-2,2-bis(4-hydroxyphenyl)ethylene | [no description available] | medium | 1 | 0 | diarylmethane | |
| equol | [no description available] | medium | 1 | 0 | hydroxyisoflavans | |
| androstan-3-ol | [no description available] | medium | 1 | 0 | 3-hydroxy steroid | androgen |
| 3,3',5,5'-tetrachlorobiphenyl-4,4'-diol | [no description available] | medium | 1 | 0 | dichlorobenzene;
hydroxybiphenyls | |
| 3,3'-Dihydroxyhexestrol | [no description available] | medium | 1 | 0 | stilbenoid | |
| 4-hydroxy-2',3',4'-5'-tetrachlorobiphenyl | [no description available] | medium | 1 | 0 | biphenyls;
tetrachlorobenzene | |
| Zearalanone | [no description available] | medium | 1 | 0 | macrolide;
resorcinols | |
| 4-androstene-3,17-diol | [no description available] | medium | 1 | 0 | 3-hydroxy steroid | androgen |
| 4'-hydroxyflavanone | [no description available] | medium | 1 | 0 | 4'-hydroxyflavanones;
monohydroxyflavanone | |
| 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene | [no description available] | medium | 1 | 0 | diarylmethane | |
| 2-hydroxyestradiol | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
2-hydroxy steroid | carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug |
| mibolerone | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid | anabolic agent;
androgen |
| metribolone | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
3-oxo steroid;
anabolic androgenic steroid | androgen |
| diethylstilbestrol | [no description available] | medium | 1 | 0 | olefinic compound;
polyphenol | antifungal agent;
antineoplastic agent;
autophagy inducer;
calcium channel blocker;
carcinogenic agent;
EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
endocrine disruptor;
xenoestrogen |
| chalcone | [no description available] | medium | 1 | 0 | chalcone | EC 3.2.1.1 (alpha-amylase) inhibitor |
| isoeugenol | [no description available] | medium | 1 | 0 | isoeugenol | |
| tamoxifen | [no description available] | medium | 1 | 0 | stilbenoid;
tertiary amino compound | angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator |
| 6-hydroxyflavanone | [no description available] | medium | 1 | 0 | monohydroxyflavanone | fungal xenobiotic metabolite |
| dimethylstilbestrol | [no description available] | medium | 1 | 0 | stilbenoid | |
| genistein | [no description available] | medium | 1 | 0 | 7-hydroxyisoflavones | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor |
| coumestrol | [no description available] | medium | 1 | 0 | coumestans;
delta-lactone;
polyphenol | anti-inflammatory agent;
antioxidant;
plant metabolite |
| 7-hydroxyflavone | [no description available] | medium | 1 | 0 | hydroxyflavonoid | |
| 4-hydroxyestradiol | [no description available] | medium | 1 | 0 | 4-hydroxy steroid | metabolite |
| 4-hydroxychalcone | [no description available] | medium | 1 | 0 | chalcones;
phenols | antihypertensive agent;
plant metabolite |
| 4'-hydroxychalcone | [no description available] | medium | 1 | 0 | chalcones;
phenols | anti-inflammatory agent;
antineoplastic agent |
| 4,4'-dihydroxystilbene | [no description available] | medium | 1 | 0 | stilbene-4,4'-diol | |
| 4-hydroxystilbene | [no description available] | medium | 1 | 0 | stilben-4-ol | |
| hydroxyl radical | [no description available] | medium | 3 | 0 | oxygen hydride;
oxygen radical;
reactive oxygen species | |
| 2,4,4'-trichlorobiphenyl | [no description available] | medium | 1 | 0 | | |
| chlorine | [no description available] | medium | 3 | 0 | diatomic chlorine;
gas molecular entity | bleaching agent |
| goethite | [no description available] | medium | 1 | 0 | | |
| 4-chlorobiphenyl | [no description available] | medium | 1 | 0 | monochlorobiphenyl | |
| 4,4'-dichlorobiphenyl | [no description available] | medium | 2 | 0 | dichlorobiphenyl;
monochlorobenzenes | |
| fenton's reagent | [no description available] | medium | 1 | 0 | | |
| 3,4,5,3',4',5'-hexachlorobiphenyl | [no description available] | medium | 2 | 0 | hexachlorobiphenyl;
trichlorobenzene | |
| 2,3,4,5,3',4',5'-heptachlorobiphenyl | [no description available] | medium | 1 | 0 | heptachlorobiphenyl;
tetrachlorobenzene;
trichlorobenzene | |
| 2,4',5-trichlorobiphenyl | [no description available] | medium | 1 | 0 | | |
| thyroxine | [no description available] | medium | 2 | 0 | 2-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine | antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone |
| triiodothyronine | [no description available] | medium | 1 | 0 | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine | human metabolite;
mouse metabolite;
thyroid hormone |
| mocetinostat | [no description available] | medium | 1 | 0 | aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline | antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent |
| arachidonic acid | [no description available] | medium | 3 | 0 | icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid | Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite |
| 2,4,6,2',4',6'-hexachlorobiphenyl | [no description available] | medium | 1 | 0 | hexachlorobiphenyl;
trichlorobenzene | |
| sodium dodecyl sulfate | [no description available] | medium | 1 | 0 | organic sodium salt | detergent;
protein denaturant |
| isosafrole | [no description available] | medium | 1 | 0 | benzodioxoles | |
| safrole | [no description available] | medium | 1 | 0 | benzodioxoles | flavouring agent;
insecticide;
metabolite;
plant metabolite |
| beta-naphthoflavone | [no description available] | medium | 1 | 0 | extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound | aryl hydrocarbon receptor agonist |
| acetone | [no description available] | medium | 1 | 0 | ketone body;
methyl ketone;
propanones;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent |
| cytochalasin b | [no description available] | medium | 1 | 0 | cytochalasin;
lactam;
lactone;
organic heterotricyclic compound | actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor |
| n-formylmethionine leucyl-phenylalanine | [no description available] | medium | 2 | 0 | tripeptide | |
| tetradecanoylphorbol acetate | [no description available] | medium | 2 | 0 | acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester | antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator |
| 2,4,6-trichlorobiphenyl | [no description available] | medium | 1 | 0 | | |
| clay | [no description available] | medium | 1 | 0 | | |
| 3,4-dihydroxyphenylacetic acid | [no description available] | medium | 1 | 0 | catechols;
dihydroxyphenylacetic acid | human metabolite |
| homovanillic acid | [no description available] | medium | 1 | 0 | guaiacols;
monocarboxylic acid | human metabolite;
mouse metabolite |
| bromodeoxyuridine | [no description available] | medium | 1 | 0 | pyrimidine 2'-deoxyribonucleoside | antimetabolite;
antineoplastic agent |
| pregnenolone carbonitrile | [no description available] | medium | 1 | 0 | aliphatic nitrile | |
| phenobarbital | [no description available] | medium | 1 | 0 | barbiturates | anticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative |
| clofibric acid | [no description available] | medium | 1 | 0 | aromatic ether;
monocarboxylic acid;
monochlorobenzenes | anticholesteremic drug;
antilipemic drug;
antineoplastic agent;
herbicide;
marine xenobiotic metabolite;
PPARalpha agonist |
| ciprofibrate | [no description available] | medium | 1 | 0 | cyclopropanes;
monocarboxylic acid;
organochlorine compound | antilipemic drug |
| wortmannin | [no description available] | medium | 1 | 0 | acetate ester;
cyclic ketone;
delta-lactone;
organic heteropentacyclic compound | anticoronaviral agent;
antineoplastic agent;
autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector;
Penicillium metabolite;
radiosensitizing agent |
| luminol | [no description available] | medium | 1 | 0 | | |
| 2,2'-dichlorobiphenyl | [no description available] | medium | 1 | 0 | | |
| hexachlorobenzene | [no description available] | medium | 1 | 0 | aromatic fungicide;
chlorobenzenes | antifungal agrochemical;
carcinogenic agent;
persistent organic pollutant |
| estradiol 3-benzoate | [no description available] | medium | 1 | 0 | 17beta-hydroxy steroid;
benzoate ester | estrogen receptor agonist;
xenoestrogen |
| benz(a)anthracene | [no description available] | medium | 1 | 0 | ortho-fused polycyclic arene;
tetraphenes | |
| 2,5,2',5'-tetrachlorobiphenyl | [no description available] | medium | 1 | 0 | dichlorobenzene;
tetrachlorobiphenyl | |
| aminolevulinic acid | [no description available] | medium | 1 | 0 | 4-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid | antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite |
| deferoxamine | [no description available] | medium | 1 | 0 | acyclic desferrioxamine | bacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore |
| uroporphyrinogen iii | [no description available] | medium | 1 | 0 | uroporphyrinogen | Escherichia coli metabolite;
mouse metabolite |
| alpha-naphthoflavone | [no description available] | medium | 1 | 0 | extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound | aryl hydrocarbon receptor agonist;
aryl hydrocarbon receptor antagonist;
EC 1.14.14.14 (aromatase) inhibitor |
| kc 400 | [no description available] | low | 0 | 0 | dichlorobenzene;
tetrachlorobiphenyl | |
| 2,3,5,6-tetrachlorobiphenyl | [no description available] | low | 0 | 0 | tetrachlorobenzene;
tetrachlorobiphenyl | |
| 2,4-dichlorophenoxyacetic acid | [no description available] | low | 0 | 0 | chlorophenoxyacetic acid;
dichlorobenzene | agrochemical;
defoliant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
environmental contaminant;
phenoxy herbicide;
synthetic auxin |
| am 251 | [no description available] | low | 0 | 0 | amidopiperidine;
carbohydrazide;
dichlorobenzene;
organoiodine compound;
pyrazoles | antidepressant;
antineoplastic agent;
apoptosis inducer;
CB1 receptor antagonist |
| apraclonidine | [no description available] | low | 0 | 0 | dichlorobenzene;
guanidines;
imidazolines | alpha-adrenergic agonist;
antiglaucoma drug;
beta-adrenergic agonist;
diagnostic agent;
ophthalmology drug |
| bithionol | [no description available] | low | 0 | 0 | aryl sulfide;
bridged diphenyl antifungal drug;
bridged diphenyl fungicide;
dichlorobenzene;
organochlorine pesticide;
polyphenol | antifungal agrochemical;
antiplatyhelmintic drug |
| clenbuterol | [no description available] | low | 0 | 0 | amino alcohol;
dichlorobenzene;
ethanolamines;
primary arylamine;
secondary amino compound;
substituted aniline | beta-adrenergic agonist;
bronchodilator agent;
sympathomimetic agent |
| dicamba | [no description available] | low | 0 | 0 | dichlorobenzene;
methoxybenzoic acid | agrochemical;
environmental contaminant;
herbicide;
synthetic auxin;
xenobiotic |
| dichlobanil | [no description available] | low | 0 | 0 | dichlorobenzene;
nitrile | agrochemical;
cellulose synthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic |
| diclofenac | [no description available] | low | 0 | 0 | amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound | antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic |
| dichlorphenamide | [no description available] | low | 0 | 0 | dichlorobenzene;
sulfonamide | antiglaucoma drug;
EC 4.2.1.1 (carbonic anhydrase) inhibitor;
ophthalmology drug |
| diuron | [no description available] | low | 0 | 0 | 3-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene | environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic |
| econazole | [no description available] | low | 0 | 0 | dichlorobenzene;
ether;
imidazoles;
monochlorobenzenes | |
| ethacrynic acid | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid | EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic |
| felodipine | [no description available] | low | 0 | 0 | dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester | anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent |
| fipronil | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
dichlorobenzene;
nitrile;
primary amino compound;
pyrazoles;
sulfoxide | |
| liquid crystal polymer | [no description available] | low | 0 | 0 | conazole fungicide;
dichlorobenzene;
organobromine compound;
oxolanes;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| irsogladine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| isoconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
ether;
imidazoles | |
| ketoconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine | |
| lamotrigine | [no description available] | low | 0 | 0 | 1,2,4-triazines;
dichlorobenzene;
primary arylamine | anticonvulsant;
antidepressant;
antimanic drug;
calcium channel blocker;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
excitatory amino acid antagonist;
geroprotector;
non-narcotic analgesic;
xenobiotic |
| lorglumide | [no description available] | low | 0 | 0 | benzamides;
dicarboxylic acid monoamide;
dichlorobenzene;
glutamic acid derivative | |
| miconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
ether;
imidazoles | |
| clorgyline | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
terminal acetylenic compound;
tertiary amino compound | antidepressant;
EC 1.4.3.4 (monoamine oxidase) inhibitor |
| 4-dichlorobenzene | [no description available] | low | 0 | 0 | dichlorobenzene | insecticide |
| methazole | [no description available] | low | 0 | 0 | dichlorobenzene | |
| propanil | [no description available] | low | 0 | 0 | anilide;
dichlorobenzene | herbicide |
| sulconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
imidazoles;
monochlorobenzenes;
organic sulfide | |
| tioconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
ether;
imidazoles;
thiophenes | |
| triclosan | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols | antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic |
| 2,6-dichlorobenzoic acid | [no description available] | low | 0 | 0 | chlorobenzoic acid;
dichlorobenzene | bacterial xenobiotic metabolite |
| 2,5-dichlorobenzoic acid | [no description available] | low | 0 | 0 | chlorobenzoic acid;
dichlorobenzene | |
| 2,4-dichlorobenzoic acid | [no description available] | low | 0 | 0 | chlorobenzoic acid;
dichlorobenzene | bacterial metabolite |
| 2-dichlorobenzene | [no description available] | low | 0 | 0 | dichlorobenzene | hepatotoxic agent;
metabolite |
| 2,4-dichlorotoluene | [no description available] | low | 0 | 0 | dichlorobenzene | |
| dicloran | [no description available] | low | 0 | 0 | aromatic fungicide;
dichlorobenzene;
nitroaniline | antifungal agrochemical |
| triclocarban | [no description available] | low | 0 | 0 | dichlorobenzene;
monochlorobenzenes;
phenylureas | antimicrobial agent;
antiseptic drug;
disinfectant;
environmental contaminant;
xenobiotic |
| dichlorprop | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
monocarboxylic acid | |
| linuron | [no description available] | low | 0 | 0 | dichlorobenzene;
phenylureas | agrochemical;
environmental contaminant;
herbicide;
xenobiotic |
| chlorfenvinphos | [no description available] | low | 0 | 0 | dichlorobenzene;
organic phosphate;
organochlorine acaricide;
organochlorine insecticide;
organophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
| 1,3-dichlorobenzene | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2,6-dichloroindophenol | [no description available] | low | 0 | 0 | dichlorobenzene;
quinone imine | |
| 3,3',4',5-tetrachlorosalicylanilide | [no description available] | low | 0 | 0 | dichlorobenzene;
salicylanilides | drug allergen |
| dichlorobenzyl alcohol | [no description available] | low | 0 | 0 | benzyl alcohols;
dichlorobenzene | antiseptic drug |
| 2,6-dichlorobenzamide | [no description available] | low | 0 | 0 | benzamides;
dichlorobenzene | herbicide;
marine xenobiotic metabolite |
| 3,4-dichlorophenylurea | [no description available] | low | 0 | 0 | dichlorobenzene;
phenylureas | marine xenobiotic metabolite |
| chloroneb | [no description available] | low | 0 | 0 | aromatic fungicide;
dichlorobenzene;
dimethoxybenzene | antifungal agrochemical |
| dicloxacillin | [no description available] | low | 0 | 0 | dichlorobenzene;
penicillin | antibacterial drug |
| clonidine hydrochloride | [no description available] | low | 0 | 0 | dichlorobenzene | |
| lofexidine | [no description available] | low | 0 | 0 | aromatic ether;
carboxamidine;
dichlorobenzene;
imidazoles | alpha-adrenergic agonist;
antihypertensive agent |
| leptophos | [no description available] | low | 0 | 0 | bromobenzenes;
dichlorobenzene;
organic phosphonate;
phosphonic ester | |
| pronamide | [no description available] | low | 0 | 0 | benzamides;
dichlorobenzene;
terminal acetylenic compound | agrochemical;
herbicide |
| prothiophos | [no description available] | low | 0 | 0 | dichlorobenzene;
organic thiophosphate;
organosulfur compound | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
| 2,5-dichlorobiphenyl | [no description available] | low | 0 | 0 | dichlorobenzene;
dichlorobiphenyl | |
| 3,5-dichlorobiphenyl | [no description available] | low | 0 | 0 | dichlorobenzene;
dichlorobiphenyl | |
| enilconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
ether;
imidazoles | |
| ticrynafen | [no description available] | low | 0 | 0 | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes | antihypertensive agent;
hepatotoxic agent;
loop diuretic |
| 2-(4-(2,4-dichlorophenoxy)phenoxy)propionic acid | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
diether;
monocarboxylic acid | |
| lonidamine | [no description available] | low | 0 | 0 | dichlorobenzene;
indazoles;
monocarboxylic acid | antineoplastic agent;
antispermatogenic agent;
EC 2.7.1.1 (hexokinase) inhibitor;
geroprotector |
| vinclozolin | [no description available] | low | 0 | 0 | dicarboximide;
dichlorobenzene;
olefinic compound;
oxazolidinone | |
| dichlorfop-methyl | [no description available] | low | 0 | 0 | aromatic ether;
dichlorobenzene;
diether;
methyl ester | |
| muzolimine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| azaconazole | [no description available] | low | 0 | 0 | conazole fungicide;
cyclic ketal;
dichlorobenzene;
dioxolane;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| propiconazole | [no description available] | low | 0 | 0 | conazole fungicide;
cyclic ketal;
dichlorobenzene;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor;
environmental contaminant;
xenobiotic |
| butoconazole | [no description available] | low | 0 | 0 | aryl sulfide;
conazole antifungal drug;
dichlorobenzene;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes | |
| dichlozolinate | [no description available] | low | 0 | 0 | dicarboximide;
dichlorobenzene;
ethyl ester;
oxazolidinone | |
| fenticonazole | [no description available] | low | 0 | 0 | aryl sulfide;
dichlorobenzene;
ether;
imidazoles | |
| itraconazole | [no description available] | low | 0 | 0 | aromatic ether;
conazole antifungal drug;
cyclic ketal;
dichlorobenzene;
dioxolane;
N-arylpiperazine;
triazole antifungal drug;
triazoles | EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
Hedgehog signaling pathway inhibitor;
P450 inhibitor |
| aripiprazole | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactam;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
quinolone | drug metabolite;
H1-receptor antagonist;
second generation antipsychotic;
serotonergic agonist |
| tobanum | [no description available] | low | 0 | 0 | dichlorobenzene | |
| sertaconazole | [no description available] | low | 0 | 0 | 1-benzothiophenes;
dichlorobenzene;
ether;
imidazoles | |
| hexaconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
tertiary alcohol;
triazoles | chelator |
| sertraline | [no description available] | low | 0 | 0 | dichlorobenzene;
secondary amino compound;
tetralins | antidepressant;
serotonin uptake inhibitor |
| aceclofenac | [no description available] | low | 0 | 0 | amino acid;
carboxylic ester;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug |
| fluphenacur | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organofluorine compound | |
| guanoclor | [no description available] | low | 0 | 0 | dichlorobenzene | |
| tridiphane | [no description available] | low | 0 | 0 | dichlorobenzene | |
| tetraconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
ether;
organofluorine compound;
triazoles | |
| n-(2,4-dichloro-5-(4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl)phenyl)methanesulfonamide | [no description available] | low | 0 | 0 | dichlorobenzene;
organofluorine compound;
sulfonamide;
triazoles | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide |
| fluquinconazole | [no description available] | low | 0 | 0 | conazole fungicide;
dichlorobenzene;
organofluorine compound;
quinazolines;
triazole fungicide;
triazoles | antifungal agrochemical;
EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor |
| tolclofos-methyl | [no description available] | low | 0 | 0 | dichlorobenzene;
organic thiophosphate | antifungal agrochemical |
| penconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
triazoles | |
| chlorfluazuron | [no description available] | low | 0 | 0 | benzoylurea insecticide;
dichlorobenzene;
organochlorine insecticide;
organofluorine insecticide | |
| fenpiclonil | [no description available] | low | 0 | 0 | dichlorobenzene;
nitrile;
pyrroles | antifungal agrochemical |
| teflubenzuron | [no description available] | low | 0 | 0 | dichlorobenzene;
difluorobenzene;
N-acylurea | environmental contaminant;
insecticide;
xenobiotic |
| hexafluoron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
N-acylurea;
organochlorine insecticide;
organofluorine insecticide | |
| sr141716 | [no description available] | low | 0 | 0 | amidopiperidine;
carbohydrazide;
dichlorobenzene;
monochlorobenzenes;
pyrazoles | anti-obesity agent;
appetite depressant;
CB1 receptor antagonist |
| 4,4'-bis(methylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl | [no description available] | low | 0 | 0 | biphenyls;
dichlorobenzene;
sulfone | |
| 4'-hydroxydiclofenac | [no description available] | low | 0 | 0 | dichlorobenzene;
monocarboxylic acid;
phenols;
secondary amino compound | allergen;
drug metabolite |
| zoxamide | [no description available] | low | 0 | 0 | alpha-chloroketone;
benzamides;
dichlorobenzene | |
| 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone | [no description available] | low | 0 | 0 | dichlorobenzene;
differentiation-inducing factor;
monomethoxybenzene;
resorcinols | eukaryotic metabolite;
signalling molecule |
| 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone | [no description available] | low | 0 | 0 | dichlorobenzene;
differentiation-inducing factor;
monomethoxybenzene;
resorcinols | eukaryotic metabolite;
signalling molecule |
| cgp 52432 | [no description available] | low | 0 | 0 | dichlorobenzene | |
| spirodiclofen | [no description available] | low | 0 | 0 | dichlorobenzene;
gamma-lactone;
organochlorine acaricide;
oxaspiro compound | |
| n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide | [no description available] | low | 0 | 0 | anilide fungicide;
aromatic amide;
dichlorobenzene;
monocarboxylic acid amide;
phenols | antifungal agrochemical;
EC 1.14.13.72 (methylsterol monooxygenase) inhibitor;
sterol biosynthesis inhibitor |
| 2-(2,4-dichlorophenoxy)-N-(3-pyridinyl)acetamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 3,5-dichlorotyrosine | [no description available] | low | 0 | 0 | chloroamino acid;
dichlorobenzene;
dihalogenated L-tyrosine;
non-proteinogenic L-alpha-amino acid | |
| pd 173955 | [no description available] | low | 0 | 0 | aryl sulfide;
dichlorobenzene;
methyl sulfide;
pyridopyrimidine | tyrosine kinase inhibitor |
| mln 4760 | [no description available] | low | 0 | 0 | dichlorobenzene;
L-histidine derivative;
L-leucine derivative | anti-inflammatory agent;
EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor |
| olanexidine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-(2,4-dichlorophenoxy)-N-(2-furanylmethyl)acetamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-[[5-(2,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]thio]acetic acid butyl ester | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-[[5-(2,4-dichlorophenyl)-1,3,4-oxadiazol-2-yl]thio]acetic acid ethyl ester | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 5,6-dichloro-1-ethyl-1,3-dihydro-2h-benzimidazol-2-one | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 3-[(2,6-dichlorophenyl)methylthio]-4-methyl-5-thiophen-2-yl-1,2,4-triazole | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)ethanol | [no description available] | low | 0 | 0 | dichlorobenzene | |
| N-[2-[5-[(2,4-dichlorophenyl)methylsulfonyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamic acid tert-butyl ester | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 6-(2,4-dichlorophenyl)-1,5-diazabicyclo[3.1.0]hexane | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 3-[(2,4-dichlorophenyl)methylthio]-1,2,4-thiadiazol-5-amine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-(2,4-dichlorophenyl)-3,5-dihydro-1H-pyrazolo[3,4-d]triazol-6-amine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 5-[(2,4-dichlorophenoxy)methyl]-N-[1-[(2-fluorophenyl)methyl]-3-pyrazolyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 1-[[2-(2,4-dichlorophenoxy)-1-oxoethyl]amino]-3-(4-fluorophenyl)thiourea | [no description available] | low | 0 | 0 | dichlorobenzene | |
| [4-[[5-(2,4-dichlorophenyl)-3-isoxazolyl]-oxomethyl]-1-piperazinyl]-(2-furanyl)methanone | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 5-(2,4-dichlorophenyl)-N-(4-methyl-2-thiazolyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 5-(2,5-dichlorophenyl)-N-(2-propyl-5-tetrazolyl)-2-furancarboxamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 4-[2-[(3,4-dichlorophenyl)methylthio]-6-[(methylthio)methyl]-4-pyrimidinyl]morpholine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 3-[5-[(3,4-dichlorophenyl)methylthio]-4-ethyl-1,2,4-triazol-3-yl]-1-phenyl-4-pyridazinone | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 5-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-1,2-dihydro-1,2,4-triazole-3-thione | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-(2,4-dichlorophenyl)-5-[2-(methylthio)phenyl]-1,3,4-oxadiazole | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 4-[2-[(2,4-dichlorophenyl)methylthio]-6-methyl-4-pyrimidinyl]morpholine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 4-(2,4-dichlorophenoxy)-N-(3-pyridinyl)butanamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 4-(2,4-dichlorophenoxy)butanoic acid [2-oxo-2-[(phenylmethyl)amino]ethyl] ester | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-((3-(2,3-dichlorophenoxy)propyl)amino)ethanol | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 2-(2,4-dichloro-6-methylphenoxy)-N-(2-furanylmethyl)acetamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 4-[3-(2,4-dichlorophenyl)-5-isoxazolyl]-2-pyrimidinamine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| yoda 1 | [no description available] | low | 0 | 0 | aromatic compound;
dichlorobenzene;
organic sulfide;
pyrazines;
thiadiazoles | glycine transporter 2 inhibitor;
piezo1 agonist |
| 3-[[(2,4-dichlorophenyl)methylthio]methyl]-4-propan-2-yl-1H-1,2,4-triazole-5-thione | [no description available] | low | 0 | 0 | dichlorobenzene | |
| N-[amino(1-pyrrolidinyl)methylidene]-3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| N-[2-(2,4-dichlorophenyl)ethyl]-2-[[5-[1-(dimethylamino)propyl]-1,3,4-oxadiazol-2-yl]thio]acetamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| nnd 502 | [no description available] | low | 0 | 0 | dichlorobenzene | |
| fenchlorazole-ethyl | [no description available] | low | 0 | 0 | dichlorobenzene | |
| omoconazole | [no description available] | low | 0 | 0 | dichlorobenzene | |
| u-50488 | [no description available] | low | 0 | 0 | dichlorobenzene;
monocarboxylic acid amide;
N-alkylpyrrolidine | analgesic;
antitussive;
calcium channel blocker;
diuretic;
kappa-opioid receptor agonist |
| vx-745 | [no description available] | low | 0 | 0 | aryl sulfide;
dichlorobenzene;
difluorobenzene;
pyrimidopyridazine | anti-inflammatory drug;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor |
| 5-hydroxydiclofenac | [no description available] | low | 0 | 0 | dichlorobenzene;
monocarboxylic acid;
phenols;
secondary amino compound | allergen;
drug metabolite |
| fipronil sulfone | [no description available] | low | 0 | 0 | (trifluoromethyl)benzenes;
dichlorobenzene;
nitrile;
pyrazoles;
sulfone | marine xenobiotic metabolite |
| 3-(2-chlorophenyl)-N-[5-(2,4-dichlorophenyl)-1,3,4-thiadiazol-2-yl]-5-methyl-4-isoxazolecarboxamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 3-[2-(2,4-dichlorophenoxy)ethoxy]-6-methyl-2-nitropyridine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| 5-[(2,4-dichlorophenoxy)methyl]-N-[3,5-dimethyl-1-[(2,3,4,5,6-pentafluorophenyl)methyl]-4-pyrazolyl]-2-furancarboxamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| (3,5-dichloroanilino)thiourea | [no description available] | low | 0 | 0 | dichlorobenzene | |
| N(2)-carbamimidoyl-N-{2-[4-(3-{4-[(5-carboxyfuran-2-yl)methoxy]-2,3-dichlorophenyl}-1-methyl-1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoethyl}-D-leucinamide | [no description available] | low | 0 | 0 | D-leucine derivative;
dichlorobenzene;
furoic acid;
glycine derivative;
guanidines;
pyrazolylpiperidine | |
| bosutinib | [no description available] | low | 0 | 0 | aminoquinoline;
aromatic ether;
dichlorobenzene;
N-methylpiperazine;
nitrile;
tertiary amino compound | antineoplastic agent;
tyrosine kinase inhibitor |
| oxiconazole | [no description available] | low | 0 | 0 | conazole antifungal drug;
dichlorobenzene;
imidazole antifungal drug;
imidazoles;
oxime O-ether | antiinfective agent |
| guanabenz acetate | [no description available] | low | 0 | 0 | dichlorobenzene | geroprotector |
| guanabenz | [no description available] | low | 0 | 0 | dichlorobenzene | |
| N-(3,4-dichlorophenyl)-6-(1-imidazolyl)-3-pyridazinamine | [no description available] | low | 0 | 0 | dichlorobenzene | |
| diniconazole | [no description available] | low | 0 | 0 | dichlorobenzene;
olefinic compound;
secondary alcohol;
triazoles | |
| chlorproguanil | [no description available] | low | 0 | 0 | dichlorobenzene | |
| noviflumuron | [no description available] | low | 0 | 0 | aromatic ether;
benzoylurea insecticide;
dichlorobenzene;
organofluorine compound | |
| chir 99021 | [no description available] | low | 0 | 0 | aminopyridine;
aminopyrimidine;
cyanopyridine;
diamine;
dichlorobenzene;
imidazoles;
secondary amino compound | EC 2.7.11.26 (tau-protein kinase) inhibitor |
| vilanterol | [no description available] | low | 0 | 0 | benzyl alcohols;
dichlorobenzene;
ether;
phenols;
secondary amino compound | beta-adrenergic agonist;
bronchodilator agent |
| gw 842166x | [no description available] | low | 0 | 0 | dichlorobenzene | |
| pha 665752 | [no description available] | low | 0 | 0 | dichlorobenzene;
enamide;
indolones;
N-acylpyrrolidine;
pyrrolecarboxamide;
secondary carboxamide;
sulfone;
tertiary carboxamide | antineoplastic agent;
c-Met tyrosine kinase inhibitor |
| tafamidis | [no description available] | low | 0 | 0 | 1,3-benzoxazoles;
dichlorobenzene;
monocarboxylic acid | central nervous system drug |
| fluopicolide | [no description available] | low | 0 | 0 | benzamide fungicide;
benzamides;
dichlorobenzene;
monochloropyridine;
organofluorine compound | antifungal agrochemical |
| gamendazole | [no description available] | low | 0 | 0 | alpha,beta-unsaturated monocarboxylic acid;
dichlorobenzene;
indazoles;
olefinic compound;
organofluorine compound | antispermatogenic agent;
eukaryotic translation elongation factor 1alpha 1 inhibitor;
Hsp90 inhibitor;
synthetic oral contraceptive |
| at 7519 | [no description available] | low | 0 | 0 | dichlorobenzene;
piperidines;
pyrazoles;
secondary carboxamide | antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor |
| s 1812 | [no description available] | low | 0 | 0 | dichlorobenzene;
organochlorine insecticide;
organofluorine insecticide | |
| 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine | [no description available] | low | 0 | 0 | aminopyridine;
aromatic ether;
dichlorobenzene;
organofluorine compound;
pyrazolylpiperidine;
racemate | antineoplastic agent;
biomarker;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor |
| 2-[(2,4-dichlorophenyl)methylthio]-1-methylimidazole | [no description available] | low | 0 | 0 | dichlorobenzene | |
| avilamycin a | [no description available] | low | 0 | 0 | benzoate ester;
cyclic acetal;
dichlorobenzene;
oligosaccharide derivative;
ortho ester;
oxaspiro compound;
phenols;
tertiary alpha-hydroxy ketone | antimicrobial agent;
bacterial metabolite |
| gsk 1016790a | [no description available] | low | 0 | 0 | 1-benzothiophenes;
aromatic primary alcohol;
dichlorobenzene;
N-acylpiperazine;
sulfonamide;
tertiary carboxamide | TRPV4 agonist |
| poziotinib | [no description available] | low | 0 | 0 | acrylamides;
aromatic ether;
dichlorobenzene;
diether;
monofluorobenzenes;
N-acylpiperidine;
quinazolines;
secondary amino compound;
substituted aniline | antineoplastic agent;
apoptosis inducer;
epidermal growth factor receptor antagonist |
| ixazomib | [no description available] | low | 0 | 0 | benzamides;
boronic acids;
dichlorobenzene;
glycine derivative | antineoplastic agent;
apoptosis inducer;
drug metabolite;
orphan drug;
proteasome inhibitor |
| N-[(2S,3S)-2-[[(3,4-dichlorophenyl)methyl-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-2-(1-tetrazolyl)acetamide | [no description available] | low | 0 | 0 | dichlorobenzene | |
| aripiprazole lauroxil | [no description available] | low | 0 | 0 | aromatic ether;
delta-lactam;
dichlorobenzene;
dodecanoate ester;
N-alkylpiperazine;
N-arylpiperazine;
quinolone | H1-receptor antagonist;
prodrug;
second generation antipsychotic;
serotonergic agonist |
| 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)-phenylamino)pyrimidin-4-yl)-1-methylurea | [no description available] | low | 0 | 0 | aminopyrimidine;
dichlorobenzene;
N-alkylpiperazine;
N-arylpiperazine;
phenylureas | antineoplastic agent;
fibroblast growth factor receptor antagonist |
| chir 98014 | [no description available] | low | 0 | 0 | aminopyrimidine;
C-nitro compound;
diaminopyridine;
dichlorobenzene;
imidazoles;
secondary amino compound | antineoplastic agent;
apoptosis inducer;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
hypoglycemic agent;
tau aggregation inhibitor;
Wnt signalling activator |
| LimKi 3 | [no description available] | low | 0 | 0 | 1,3-thiazoles;
dichlorobenzene;
organofluorine compound;
pyrazoles;
secondary carboxamide | LIM kinase inhibitor |
| 2-(4-chloroanilino)-5-[(2,3-dichlorophenyl)methyl]-4-thiazolone | [no description available] | low | 0 | 0 | dichlorobenzene | |