2,4,6,2',4',6'-hexachlorobiphenyl

Description

2,4,6,2',4',6'-hexachlorobiphenyl (PCB 153) is a highly chlorinated polychlorinated biphenyl (PCB) congener. It is a persistent organic pollutant (POP) and is known for its resistance to environmental degradation. PCBs were widely used in industrial applications due to their fire-retardant and insulating properties, but their production and use were phased out due to their toxicity and environmental persistence. PCB 153, like other PCBs, is a known endocrine disruptor, meaning it can interfere with the hormone systems of living organisms. It has been linked to reproductive problems, developmental defects, and immune system suppression. PCB 153 is bioaccumulative, meaning it can build up in the food chain, reaching high concentrations in top predators. Due to its widespread environmental contamination and potential health risks, PCB 153 is extensively studied to understand its fate and transport in the environment, its effects on wildlife and human health, and to develop strategies for remediation and risk management.'

2,2',4,4',6,6'-hexachlorobiphenyl : A hexachlorobiphenyl that is biphenyl in which both of the phenyl rings are substituted at positons 2, 4, and 6 by chlorines. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]