Page last updated: 2024-12-06

1,3-di-(4-imidazolino-2-methoxyphenoxy)propane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

You're asking about a compound with a very specific chemical structure, **1,3-di-(4-imidazolino-2-methoxyphenoxy)propane**. While I can analyze chemical structures, I don't have access to a database that stores detailed information about the specific properties and research uses of every possible compound.

**Here's what we can break down:**

* **The Structure:** The compound name reveals a lot about its structure.
* **1,3-di:** This indicates that there are two identical parts of the molecule attached to a propane chain (three carbons with single bonds).
* **(4-imidazolino-2-methoxyphenoxy):** This describes a complex ring system.
* **Phenoxy:** This means there's a benzene ring (a six-membered ring with alternating double bonds) with an oxygen atom attached.
* **2-methoxy:** This indicates a methoxy group (CH3O-) attached to the second position of the benzene ring.
* **4-imidazolino:** This means an imidazoline ring (a five-membered ring containing nitrogen atoms) is attached to the fourth position of the benzene ring.

* **Potential Research Applications:**
* **Pharmacological Activity:** The combination of a benzene ring, an imidazoline ring, and methoxy group often points towards compounds with potential pharmacological activity. These structures are frequently found in molecules that interact with biological systems, such as:
* **Anti-inflammatory agents:** The imidazoline ring is common in antihistamines and other anti-inflammatory drugs.
* **Cardiovascular agents:** The methoxy group can influence the way a molecule interacts with receptors involved in heart function.
* **Materials Science:** The compound might have interesting properties for use in materials science. Its rigid structure could contribute to its potential as a:
* **Polymer component:** The long chain could be incorporated into polymers, influencing their properties like flexibility or strength.
* **Ligand for metal complexation:** The nitrogen atoms in the imidazoline ring could bind to metal ions, forming complexes with specific applications.

**Finding More Information:**

* **Chemical Databases:** To find specific information about this compound, you'll need to use chemical databases like PubChem, SciFinder, or Reaxys. These databases often contain experimental data, synthesis methods, and potential biological activity.
* **Academic Literature:** Searching for the compound name or similar structures in scientific publications through databases like Google Scholar or PubMed can reveal research papers discussing its properties and applications.

**Important Note:** Without further information, it's impossible to say definitively why this specific compound might be important for research. The importance of a compound is often determined by its unique properties and how it interacts with biological systems or materials.

1,3-di-(4-imidazolino-2-methoxyphenoxy)propane: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID60323
CHEMBL ID1161187
SCHEMBL ID14599544
MeSH IDM0179492

Synonyms (23)

Synonym
1,3-bis[4-(imidazolin-2-yl)-2-methoxyphenoxy]propane
2-[4-[3-[4-(4,5-dihydro-1h-imidazol-2-yl)-2-methoxy-phenoxy]propoxy]-3-methoxy-phenyl]-4,5-dihydro-1h-imidazole
129051-03-2
2-[4-[3-[4-(4,5-dihydro-1h-imidazol-2-yl)-2-methoxyphenoxy]propoxy]-3-methoxyphenyl]-4,5-dihydro-1h-imidazole
CHEMBL1161187
1,3-bis(4-(imidazolin-2-yl)-2-methoxyphenoxy)propane
119014-74-3
dmp lactate
9jbo5f5llm ,
109444-03-3
1,3-dimpp
1h-imidazole, 2,2'-(1,3-propanediylbis(oxy(3-methoxy-4,1-phenylene))bis(4,5-dihydro-
unii-9jbo5f5llm
2,2'-(1,3-propanediylbis(oxy(3-methoxy-4,1-phenylene)))bis(4,5-dihydro-1h-imidazole
1,3-di-(4-imidazolino-2-methoxyphenoxy)propane lactate
1,3-di-(4-imidazolino-2-methoxyphenoxy)propane
SCHEMBL14599544
1,3-di(4-imidazolino-2-methoxyphenoxy) propane
o,o'-bis(4-(imidazolin-2-yl)-(2-methoxy)phenyl)-1,3-propanediol
1h-imidazole, 2,2'-(1,3-propanediylbis(oxy(3-methoxy-4,1-phenylene)))bis(4,5-dihydro-
DTXSID60911168
2,2'-{propane-1,3-diylbis[oxy(3-methoxy-4,1-phenylene)]}di(4,5-dihydro-1h-imidazole)
2-[4-[3-[4-(4,5-dihydro-1h-imidazol-2-yl)-2-methoxy-phenoxy]propoxy]-3-methoxy-phenyl]-4,5-dihydro-1

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The terminal elimination half-life was 37."( The pharmacokinetics of 1,3-di(4-imidazolino-2-methoxyphenoxy) propane.lactate (DMP.lactate), a new agent against opportunistic infections, in male beagle dogs.
Bekersky, I; Hanson, G; Mong, S; Puhl, RJ,
)
0.13

Bioavailability

ExcerptReferenceRelevance
"The pharmacokinetics and oral bioavailability of 1,3-di(4-imidazolino-2-methoxyphenoxy) propane."( The pharmacokinetics of 1,3-di(4-imidazolino-2-methoxyphenoxy) propane.lactate (DMP.lactate), a new agent against opportunistic infections, in male beagle dogs.
Bekersky, I; Hanson, G; Mong, S; Puhl, RJ,
)
0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID101036Inhibition on leishmania mexicana amazonensis.1997Journal of medicinal chemistry, Dec-19, Volume: 40, Issue:26
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (3)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]