Syringoma

A benign tumor of the sweat glands which is usually multiple and results from malformation of sweat ducts. It is uncommon and more common in females than in males. It is most likely to appear at adolescence, and further lesions may develop during adult life. It does not appear to be hereditary. (Rook et al., Textbook of Dermatology, 4th ed, pp2407-8)

Synonym
Syringoma

Excerpt	Reference
"Milium-like syringoma is an unusual clinical variant of the tumor, and this is, to our knowledge, the first reported case occurring perianally."	( Higaki, Y; Kawashima, M; Nogita, T, 1995)
"Although syringoma is a common adnexal tumor, acral presentation is very rare."	( Clark, RE; Garcia, C; Grichnik, J; Krunic, AL; Viehman, G, 1997)
"Eruptive syringomas are uncommon benign adnexal neoplasms."	( Camacho, AP; Cockerell, CJ; Frazier, CC, 2001)
"Syringomas are benign lesions most commonly appearing around the eyelids and in malar areas, but they have also been described on other body sites."	( Cerroni, L; Kopera, D; Soyer, HP, 1999)
"Vulvar syringoma is not very rare and should be considered in the differential diagnosis of vulvar pruritus."	( Chuang, YH; Hong, HS; Huang, YH; Kuo, TT; Yang, LC, 2003)
"Malignant syringoma is a rare differential diagnosis of face skin tumors."	( Bewer, F; Förster, C; Welkoborsky, HJ, 2004)
"Milium-like syringoma is a variant of syringoma first described in 1987."	( Chu, JS; Hu, CH; Lee, WR; Lin, YH; Wang, KH, 2004)
"Syringomas are relatively common benign adnexal tumors, predominantly developing in middle-aged women."	( Kim, WS; Lee, DY; Lee, ES; Lee, JH; Park, HJ; Yang, JM, 2007)
"Syringomas are common benign eccrine ductal adnexial tumors, commonly found in periorbital area."	( Farias, MM; Hasson, A; Navarrete, C; Nicklas, C, 2012)
"Syringomas are benign tumours that develop predominantly in the periorbital areas of women."	( Kitano, Y, 2016)
"Although syringoma is a common benign tumour of the sudoriferous gland, there is also an extremely rare malignant form known as syringoid eccrine carcinoma (SEC)."	( Dvořák, Z; Heinz, P; Krsička, P; Michálek, J; Pink, R, 2022)
"Syringomas are benign adnexal neoplasms that may induce psychological stress when they are large or disfiguring or present in delicate regions such as the periorbital area."	( Alsaidan, MS, 2022)
"Syringoma is a common but refractory benign skin tumor."	( Chen, W; Feng, W; Gu, Q; Wu, S; Yao, B, 2023)

Excerpt	Reference
"This is the first report of argon laser treatment of syringoma in a patient with multiple vulvar syringomas in association with pruritus vulvae and carcinophobia."	( Cerroni, L; Kopera, D; Soyer, HP, 1999)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (1.43)	23.3326
1990's	15 (21.43)	12.5806
2000's	27 (38.57)	18.1394
2010's	22 (31.43)	28.8240
2020's	5 (7.14)	9.53

Drug	Relationship Strength	Studies
salicylic acid	low	9
iodine	low	1
carbamazepine	low	1
khellin	low	1
oxonic acid	low	1
tegafur	low	1
tyrosine	low	1
trichloroacetic acid	low	2
pyrroles	low	1
betamethasone	low	1
argon	low	1
erbium	low	1
yttrium	low	1
tridemorph	low	1
benoxaprofen	low	1
propiconazole	low	6
atropine	low	1
adelmidrol	low	1
inositol 3-phosphate	low	1
tretinoin	low	1
bromochloroacetic acid	low	16
tranilast	low	2
isotretinoin	low	2
phenylephrine hydrochloride	low	1
acitretin	low	1
su 11248	low	1
aluminum	low	1
gadolinium dtpa	low	1
plx4032	low	1

Protein Targets (859)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Luciferase	5	0	0	5
USP1 protein, partial	6	0	0	6
TDP1 protein	8	0	0	8
Microtubule-associated protein tau	4	0	0	4
AR protein	12	0	0	12
aldehyde dehydrogenase 1 family, member A1	8	0	0	8
glucocorticoid receptor [Homo sapiens]	10	0	0	10
estrogen nuclear receptor alpha	14	0	0	14
peroxisome proliferator activated receptor gamma	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	8	0	0	8
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	10	0	0	10
vitamin D3 receptor isoform VDRA	4	0	0	4
thyroid hormone receptor beta isoform 2	5	0	0	5
flap endonuclease 1	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
geminin	8	0	0	8
peripheral myelin protein 22	5	0	0	5
survival motor neuron protein isoform d	5	0	0	5
histone acetyltransferase KAT2A isoform 1	4	0	0	4
ATP-binding cassette sub-family C member 3	0	7	0	7
Multidrug resistance-associated protein 4	0	7	0	7
Bile salt export pump	0	4	0	4
Bile salt export pump	0	10	0	10
Rap guanine nucleotide exchange factor 3	1	0	0	1
Cellular tumor antigen p53	8	0	0	8
Rap guanine nucleotide exchange factor 4	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
GLI family zinc finger 3	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
retinoid X nuclear receptor alpha	8	0	0	8
pregnane X nuclear receptor	9	0	0	9
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	1	0	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	1	6
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M1	0	2	1	5
Muscarinic acetylcholine receptor M3	0	2	1	5
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M2	0	2	1	6
Muscarinic acetylcholine receptor M1	0	2	1	6
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	2	1	5
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	1	0	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	6	0	6
pregnane X receptor	3	0	0	3
progesterone receptor	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	3	0	0	3
estrogen-related nuclear receptor alpha	9	0	0	9
farnesoid X nuclear receptor	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	3	0	0	3
IDH1	3	0	0	3
aryl hydrocarbon receptor	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
thyroid hormone receptor beta isoform a	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
Voltage-dependent calcium channel gamma-2 subunit	5	0	0	5
Glucocorticoid receptor	0	4	0	4
Glycine receptor subunit alpha-1	0	4	0	4
Glutamate receptor 2	5	0	0	5
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
ORF73	0	0	1	1
RAR-related orphan receptor gamma	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
thyroid stimulating hormone receptor	4	0	0	4
Nuclear receptor ROR-gamma	1	1	1	3
Chain A, Beta-lactamase	4	0	0	4
acetylcholinesterase	2	0	0	2
thyroid stimulating hormone receptor	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
Vpr	2	0	0	2
lamin isoform A-delta10	5	0	0	5
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	3	1	4
UDP-glucuronosyltransferase 2B7	0	0	0	1
Cytochrome P450 2B6	0	0	1	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Cytochrome P450 2J2	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
activating transcription factor 6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Chain A, Ferritin light chain	3	0	0	3
Chain A, Cruzipain	2	0	0	2
thioredoxin reductase	6	0	0	6
ATAD5 protein, partial	3	0	0	3
estrogen receptor 2 (ER beta)	3	0	0	3
regulator of G-protein signaling 4	2	0	0	2
67.9K protein	1	0	0	1
Parkin	3	0	0	3
peroxisome proliferator-activated receptor delta	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
Caspase-7	2	0	0	2
Bloom syndrome protein isoform 1	4	0	0	4
peripheral myelin protein 22 isoform 1	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
caspase-3	2	0	0	2
heat shock protein beta-1	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
Ornithine decarboxylase	0	0	0	2
Adenosine receptor A3	0	4	0	4
Retinoic acid receptor alpha	0	2	2	4
Alpha-1B adrenergic receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	2	0	2
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Mitogen-activated protein kinase 1	0	2	2	4
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	4	0	4
Cellular retinoic acid-binding protein 1	0	0	2	2
Mitogen-activated protein kinase 14	0	1	2	3
Olfactory receptor 51E2	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
glp-1 receptor, partial	5	0	0	5
GALC protein	2	0	0	2
G	2	0	0	2
cytochrome P450 2D6	1	0	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
cytochrome P450 3A4 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	4	0	0	4
Interferon beta	4	0	0	4
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1A2	0	2	1	3
Cytochrome P450 3A4	0	2	1	3
Cytochrome P450 2D6	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit delta	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	4	0	0	4
Cytochrome P450 2C19	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	4	0	0	4
Cytochrome P450 1B1	0	1	0	1
GABA theta subunit	4	0	0	4
Inositol hexakisphosphate kinase 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit epsilon	4	0	0	4
cytochrome P450 2C9, partial	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
chromobox protein homolog 1	7	0	0	7
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Spike glycoprotein	3	0	0	3
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
EWS/FLI fusion protein	1	0	0	1
tyrosine-protein kinase Yes	2	0	0	2
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	2	2
Serine/threonine-protein kinase PLK4	0	1	2	3
ATP-dependent RNA helicase DDX3X	0	0	2	2
Pirin	0	1	0	1
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase Chk1	0	1	2	3
Aurora kinase A	0	1	2	3
Cyclin-G-associated kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	2	2
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	2	2	4
Tyrosine-protein kinase ABL1	0	1	3	4
Epidermal growth factor receptor	0	2	2	4
GTPase KRas	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	2	5
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	2	2
Protein kinase C beta type	0	0	2	2
Insulin receptor	0	1	2	3
Tyrosine-protein kinase Lck	0	1	2	3
Tyrosine-protein kinase Fyn	0	0	2	2
Cyclin-dependent kinase 1	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	2	2
Tyrosine-protein kinase Lyn	0	0	2	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	2	3
Insulin-like growth factor 1 receptor	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	1	2	3
Tyrosine-protein kinase HCK	0	1	2	3
Platelet-derived growth factor receptor beta	0	3	2	5
Tyrosine-protein kinase Fgr	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	1	2	3
Glycogen phosphorylase, brain form	0	0	2	2
Breakpoint cluster region protein	0	0	3	3
Serine/threonine-protein kinase pim-1	0	0	2	2
Fibroblast growth factor receptor 1	0	1	2	3
DNA topoisomerase 2-alpha	0	0	2	2
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
Proto-oncogene tyrosine-protein kinase Src	0	1	2	3
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Serine/threonine-protein kinase B-raf	0	1	3	5
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	2	2
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	0	2	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	3	3
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Cyclin-dependent kinase 2	0	1	2	3
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	2
Serine/threonine-protein kinase B-raf	0	1	0	1
Ephrin type-A receptor 2	0	0	2	2
Ephrin type-B receptor 2	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	1	2	3
RAC-beta serine/threonine-protein kinase	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Myosin-10	0	0	2	2
Vascular endothelial growth factor receptor 2	0	4	1	5
Dual specificity mitogen-activated protein kinase kinase 2	0	1	2	3
Receptor-type tyrosine-protein kinase FLT3	0	1	2	4
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	2	2
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Tyrosine-protein kinase Tec	0	0	2	2
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase SYK	0	0	2	2
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	2	2
Casein kinase I isoform alpha	0	1	2	3
Casein kinase I isoform delta	0	0	2	2
MAP kinase-activated protein kinase 2	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Ribosomal protein S6 kinase alpha-3	0	1	2	3
Serine/threonine-protein kinase Nek2	0	1	2	3
Serine/threonine-protein kinase Nek3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	2	2	4
LIM domain kinase 1	0	0	2	2
LIM domain kinase 2	0	0	2	2
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	3
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	1	2	3
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
Heat shock factor protein 1	0	1	0	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	1	2	3
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	1	2	3
Protein kinase C delta type	0	0	2	2
Tyrosine-protein kinase BTK	0	0	2	2
Activated CDC42 kinase 1	0	0	2	2
Epithelial discoidin domain-containing receptor 1	0	0	2	2
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	2	4
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Serine/threonine-protein kinase ATR	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	0	2	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Cyclin-dependent kinase 10	0	0	2	2
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	1	2	3
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	0	2	2
Serine/threonine-protein kinase STK11	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
Discoidin domain-containing receptor 2	0	0	2	2
AP2-associated protein kinase 1	0	1	2	3
Myosin light chain kinase 3	0	0	2	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Rab-like protein 3	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	2	2
Serine/threonine-protein kinase ULK3	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Aurora kinase B	0	1	2	3
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	1	2	3
Cyclin-dependent kinase 12	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase 26	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	3
Serine/threonine-protein kinase TBK1	0	1	2	3
Septin-9	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase 38-like	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
phosphopantetheinyl transferase	2	0	0	2
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
nonstructural protein 1	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
nuclear receptor ROR-gamma isoform 1	4	0	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
TAR DNA-binding protein 43	1	0	0	1
ATPase family AAA domain-containing protein 5	4	0	0	4
Ataxin-2	4	0	0	4
heat shock protein 90, putative	0	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
Solute carrier family 22 member 6	0	1	0	1
Polyphenol oxidase 2	0	1	0	3
Carbonic anhydrase 12	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 2	0	2	0	3
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	2
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	2	0	2
Carbonic anhydrase 4	0	1	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 6	0	1	0	2
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Prostaglandin G/H synthase 2	0	1	1	2
Carbonic anhydrase 7	0	1	0	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	1	3
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase 9	0	1	0	2
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	2
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Leukotriene C4 synthase	0	0	1	1
GLS protein	2	0	0	2
PPM1D protein	1	0	0	1
huntingtin isoform 2	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
DNA polymerase kappa isoform 1	2	0	0	2
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
NUAK family SNF1-like kinase 1	0	1	1	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	1	1	2
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Signal recognition particle receptor subunit alpha	0	0	1	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	3	1	4
Aromatase	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Platelet-derived growth factor receptor alpha	0	2	1	3
Translocator protein	0	1	0	1
Vascular endothelial growth factor receptor 1	0	2	1	3
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
Protein kinase C eta type	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	0	1
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	1	1	2
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
Bifunctional epoxide hydrolase 2	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	2	1	3
Serine/threonine-protein kinase receptor R3	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Serine/threonine-protein kinase mTOR	0	1	1	2
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
Cyclin-dependent kinase 8	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Protein delta homolog 1	0	1	1	2
Mu-type opioid receptor	0	1	0	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Protein kinase C epsilon type	0	0	1	1
Angiopoietin-1 receptor	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	1	2
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	1	1	2
Bromodomain-containing protein 9	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	1	1	2
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	1	1	2
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	1	1	2
eIF-2-alpha kinase GCN2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
dopamine D1 receptor	1	0	0	1
MSH	0	0	0	1
NFKB1 protein, partial	2	0	0	2
Thrombopoietin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
arylsulfatase A	2	0	0	2
pyruvate kinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
M-phase phosphoprotein 8	2	0	0	2
muscleblind-like protein 1 isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
Ornithine decarboxylase	1	0	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
ATP-dependent phosphofructokinase	2	0	0	2
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
thioredoxin glutathione reductase	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
60 kDa chaperonin	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
60 kDa heat shock protein, mitochondrial	0	1	0	1
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	2	4
Alpha-1D adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Alpha-synuclein	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
10 kDa heat shock protein, mitochondrial	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, HADH2 protein	1	0	0	1
Chain B, HADH2 protein	1	0	0	1
Smad3	1	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Delta	0	1	0	1
Cycloeucalenol cycloisomerase	0	1	0	1
Sterol-8,7-isomerase	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Plasma kallikrein	0	0	0	1
Adenosine receptor A1	0	0	0	1
Adenosine receptor A2a	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Carbonic anhydrase	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (70)

Protein Targets (859)

Syringoma

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (70)

Drugs Studied (36)

Protein Targets (859)