Allergic Bronchopulmonary Mycosis

Lung infections with the invasive forms of ASPERGILLUS, usually after surgery, transplantation, prolonged NEUTROPENIA or treatment with high-doses of CORTICOSTEROIDS. Invasive pulmonary aspergillosis can progress to CHRONIC NECROTIZING PULMONARY ASPERGILLOSIS or hematogenous spread to other organs.

Synonym
Pulmonary Aspergillosis - Invasive
Invasive Pulmonary Aspergillosis
Allergic Bronchopulmonary Mycosis
Chronic Necrotizing Pulmonary Aspergillosis

Excerpt	Reference
"Invasive pulmonary aspergillosis is a life-threatening infection in lung transplant recipients; however, no studies of the pharmacokinetics and pharmacodynamics (PKPD) of echinocandins in transplanted lungs have been reported."	( Conte, JE; DeVoe, C; Golden, JA; Goutelle, S; Hayes, M; Jelliffe, RW; Little, EA; Mickiene, D; Walsh, TJ, 2010)
"Acute invasive pulmonary aspergillosis is a rapidly progressive and frequently lethal infection."	( Aghamolla, T; Bacher, J; Hope, WW; Petraitiene, R; Petraitis, V; Walsh, TJ, 2010)
"Invasive pulmonary aspergillosis is a severe complication after solid organ transplant, with a high mortality rate."	( Beiras-Fernandez, A; Bigdeli, AK; Kaczmarek, I; Michel, S; Nickel, T; Reichart, B; Ueberfuhr, P, 2011)
"Invasive pulmonary aspergillosis is a rare and fatal complication in patients with cystic fibrosis (CF) who lack concomitant risk factors."	( Clements, RM; Estrada, L; Jon, CK; Mosquera, RA, 2013)
"Invasive pulmonary aspergillosis is an opportunistic mycosis, difficult to diagnose, due to the environmental fungi of the genus Aspergillus."	( Bailly, É; Chandenier, J; Desoubeaux, G, 2014)
"Invasive pulmonary aspergillosis is the most common invasive mycosis in heart transplant recipients."	( Bayram Akkurt, S; Küpeli, E; Öner Eyüboğlu, F; Sezgin, A; Ulubay, G, 2015)
"The diagnosis of invasive pulmonary aspergillosis is challenging."	( Gilliam, BL; Kleinberg, ME; Ryscavage, PA; Taremi, M; Wang, EW, 2015)
"Invasive pulmonary aspergillosis is associated with significant morbidity and mortality in patients with liver failure."	( Chen, J; Hu, J; Liu, X; Su, H; Tong, J; Xiao, L; Yang, H; Zhang, L, 2017)
"Subacute invasive pulmonary aspergillosis is now considered a type of CPA, yet it is still diagnosed and treated similarly to invasive pulmonary aspergillosis (IPA)."	( Abdallah, N; Kanj, A; Soubani, AO, 2018)
"Invasive pulmonary aspergillosis is one of the rarest opportunistic infections in HIV-infected patients."	( Hakkouni, AE; Mansouri, N, 2018)
"Invasive pulmonary aspergillosis is a deadly fungal infection with a high mortality rate, particularly in patients having undergone transplant surgery."	( Lu, X; Moon, C; Su, Y; Watts, AB; Williams, RO, 2019)
"Invasive pulmonary aspergillosis is a life-threatening disease, particularly in immunocompromised patients, despite currently available therapy."	( Cao, J; Chen, D; Gong, Y; Liu, S; Luo, Q; Yin, Y, 2020)
"Though invasive pulmonary aspergillosis is a well known complication of COVID-19 pneumonia, indolent forms of aspergillosis have been rarely described."	( Jorwal, P; Khanna, P; Kodan, P; Ray, A; Sarda, R; Singh, G; Sinha, S; Swain, S; Trikha, A; Vyas, S; Wig, N; Xess, I, 2022)
"Invasive pulmonary aspergillosis is also an uncommon fungal; these two fungal infections reported concomitantly are unprecedented."	( Bai, LH; Gan, RJ; Kuang, YK; Li, HX; Li, ZM; Tang, KJ; Wang, JY; Xie, CM; Xu, PH; Zheng, YF, 2022)
"Invasive pulmonary aspergillosis is also an uncommon fungal; these two fungal infections reported concomitantly are unprecedented."	( Bai, LH; Gan, RJ; Kuang, YK; Li, HX; Li, ZM; Tang, KJ; Wang, JY; Xie, CM; Xu, PH; Zheng, YF, 2022)

Excerpt	Reference
"Invasive pulmonary aspergillosis has been increasingly reported in nonneutropenic patients, including those with underlying respiratory diseases."	( Buzina, W; Eigl, S; Flick, H; Hoenigl, M; Koidl, C; Krause, R; Palfner, M; Prattes, J; Prüller, F; Raggam, RB; Thornton, CR; Zollner-Schwetz, I, 2014)

Excerpt	Reference
"Early diagnosis and treatment of invasive pulmonary aspergillosis (IPA) improves outcome."	( Clancy, CJ; Crespo, M; Grantham, KJ; Kleiboeker, SB; Kwak, EJ; Luong, ML; Nguyen, MH; Pakstis, D; Pilewski, J; Reddy, SK; Shields, RK; Silveira, FP; Toyoda, Y; Vadnerkar, A; Walsh, TJ; Wissel, MC, 2011)
"Five cases (of 8) of allergic bronchopulmonary mycosis that were treated with itraconazole had no recrudescence after 6 to 24 months of follow-up."	( Agarwal, K; Chowdhary, A; Gaur, SN; Kathuria, S; Meis, JF; Randhawa, HS; Roy, P; Singh, PK, 2013)
"We present a case of invasive pulmonary Aspergillosis due to corticosteroid therapy in the context of a severe Ulcerative Colitis flare."	( Ballester, MP; Bosca Watts, MM; Marti Aguado, D, 2017)
"The diagnosis and treatment of invasive pulmonary aspergillosis (IPA) are ongoing challenges in clinical practice."	( McCarthy, MW; Walsh, TJ, 2017)
"Subacute invasive pulmonary aspergillosis is now considered a type of CPA, yet it is still diagnosed and treated similarly to invasive pulmonary aspergillosis (IPA)."	( Abdallah, N; Kanj, A; Soubani, AO, 2018)
"Key messages Invasive pulmonary aspergillosis should be considered in patients with solid tumours, particularly those with underlying lung disease, lung cancer and those who received chest radiotherapy."	( Chaftari, AM; Dandachi, D; Fernández-Cruz, A; Hachem, R; Jiang, Y; Raad, I; Wilson Dib, R, 2018)
"Fast diagnosis of invasive pulmonary aspergillosis (IPA) is essential as early adequate therapy improves survival."	( Blijlevens, NMA; de Kort, E; Dunbar, A; Guldentops, E; Lagrou, K; Maertens, J; Mercier, T; Reynders, M; Rijnders, B; Schauwvlieghe, A; Verweij, PE; Vonk, AG, 2020)
"In a murine invasive pulmonary aspergillosis model, fosmanogepix or posaconazole treatment resulted in an ∼6- to 7-log reduction in conidial equivalents (CE)/g lung tissue after 96 h versus placebo."	( Alkhazraji, S; Alqarihi, A; Gebremariam, T; Gu, Y; Ibrahim, AS; Shaw, KJ; Singh, S, 2019)
"During voriconazole treatment for his invasive pulmonary aspergillosis, the patient was diagnosed with colon perforation at splenic flexure and suspected perforation of left diaphragm with communication with left pleural space."	( Bae, NY; Byun, JM; Choe, PG; Kang, CK; Kim, MS; Kim, NJ; Park, KJ; Yoon, SS, 2022)
"We present a case of probable invasive pulmonary aspergillosis due to Aspergillus flavus, in a female patient treated for an acute myeloid leukemia."	( Bellanger, AP; Berceanu, A; Caillet, A; Daguindau, E; Millon, L; Navellou, JC; Rocchi, S; Scherer, E, 2023)
"A 56-year-old woman who had allergic bronchopulmonary mycosis (ABPM) with nontuberculous mycobacteriosis (NTM) was treated with prednisone."	( Fukunishi, Y; Kajiwara, K; Kikuchi, T; Makino, H; Nagai, A; Yamamoto, H, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	25 (4.36)	18.1394
2010's	424 (74.00)	28.8240
2020's	124 (21.64)	9.53

Drug	Relationship Strength	Studies	Trials
acetone	low	1	0
adenine	low	1	0
dimethyl sulfoxide	low	1	0
formaldehyde	low	1	0
ambroxol	low	1	0
azathioprine	low	2	0
ciprofloxacin	low	1	0
diphenyleneiodonium	low	1	0
fluconazole	low	5	0
flucytosine	low	1	0
fluorouracil	low	2	0
guaifenesin	low	3	0
hydroxychloroquine	low	2	0
mesalamine	low	1	0
methenamine	low	1	0
ofloxacin	low	1	0
pentoxifylline	low	1	0
temozolomide	low	1	0
tranexamic acid	low	1	0
prednisolone	low	4	0
sorbitol	low	1	0
prednisone	low	10	0
alanine	low	2	0
galactose	medium	207	8
adenosine monophosphate	low	1	0
egtazic acid	low	2	0
gliotoxin	low	3	0
mannitol	low	2	0
cytarabine	medium	3	1
cyclopropane	low	1	0
methylprednisolone	low	10	0
penicillanic acid	medium	2	1
trehalose	low	3	0
pyrroles	low	2	0
thiazoles	low	1	0
azacitidine	low	1	0
fusarium	low	1	0
indoline	low	1	0
azomycin	low	1	0
malondialdehyde	low	1	0
gentian violet	low	1	0
acetylcysteine	low	1	0
paraquat	low	1	0
fluorescein-5-isothiocyanate	low	2	0
2-pentylfuran	low	1	0
gold	low	1	0
camptothecin	low	1	0
clodronic acid	low	1	0
daunorubicin	low	1	0
triamcinolone	low	1	0
calcium oxalate	low	1	0
ribavirin	low	1	0
propiconazole	low	1	0
piperacillin	medium	2	1
pimonidazole	low	1	0
itraconazole	medium	35	3
irinotecan	low	1	0
oseltamivir	low	3	0
triazoles	medium	120	7
voriconazole	medium	146	6
fibrinogen	low	1	0
hydroxyitraconazole	medium	1	1
tazobactam	medium	1	1
gefitinib	low	1	0
methotrexate	low	2	0
carbapenems	low	1	0
beta-lactams	low	2	0
anidulafungin	medium	5	2
desferri-ferricrocin	low	1	0
bisdethiobis(methylthio)gliotoxin	low	1	0
deferasirox	low	2	0
deoxycholic acid	low	4	0
cortisone	low	1	0
elastin	low	1	0
epiglucan	medium	53	2
laminaran	low	8	0
ergosterol	low	1	0
tretinoin	low	1	0
tacrolimus	low	5	0
mycophenolic acid	low	1	0
zithromax	low	2	0
ravuconazole	low	1	0
posaconazole	medium	34	3
l 743,872	medium	36	2
micafungin	medium	22	2
bromochloroacetic acid	low	1	0
sesquiterpenes	low	2	0
latoconazole	low	1	0
nnd 502	low	1	0
galactomannan	medium	214	8
epinephrine	low	1	0
bilirubin	low	1	0
amphotericin b	medium	72	4
pulmicort	low	1	0
humulene	low	3	0
coenzyme q10	low	1	0
sirolimus	low	1	0
c.i. fluorescent brightening agent 28	low	1	0
n,n',n''-triacetylfusarinine c	low	2	0
tanespimycin	low	1	0
fumagillin	low	2	0
isavuconazole	medium	18	3
nikkomycin	low	1	0
pseurotin	low	1	0
nystatin a1	low	1	0
ubiquinone	low	1	0
chitosan	low	3	0
amphotericin b, deoxycholate drug combination	low	4	0
ro13-9904	low	1	0
piperacillin, tazobactam drug combination	low	4	0
pci 32765	low	1	0
incb-018424	low	2	0
mannans	medium	245	8
plx4032	low	1	0
piperidines	low	1	0
interleukin-8	low	3	0
calca protein, human	low	2	0
ferricrocin	low	1	0
s 8932	low	1	0
cyclosporine	low	1	0
silybin	low	1	0
echinocandin b	low	1	0
folic acid	low	1	0
ganciclovir	low	1	0

Protein Targets (1,376)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
GLI family zinc finger 3	26	0	0	26
AR protein	34	0	0	34
estrogen receptor 2 (ER beta)	17	0	0	17
nuclear receptor subfamily 1, group I, member 3	23	0	0	23
glucocorticoid receptor [Homo sapiens]	29	0	0	29
retinoic acid nuclear receptor alpha variant 1	28	0	0	28
retinoid X nuclear receptor alpha	28	0	0	28
pregnane X nuclear receptor	23	0	0	23
estrogen nuclear receptor alpha	38	0	0	38
peroxisome proliferator activated receptor gamma	20	0	0	20
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	21	0	0	21
activating transcription factor 6	12	0	0	12
thyroid hormone receptor beta isoform 2	26	0	0	26
heat shock protein beta-1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 1	28	0	0	28
Cellular tumor antigen p53	29	0	0	29
RAR-related orphan receptor gamma	27	0	0	27
ATAD5 protein, partial	9	0	0	9
GLS protein	7	0	0	7
Microtubule-associated protein tau	11	0	0	12
Smad3	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	19	0	0	19
thyroid stimulating hormone receptor	9	0	0	9
progesterone receptor	20	0	0	20
EWS/FLI fusion protein	22	0	0	22
estrogen-related nuclear receptor alpha	30	0	0	30
aryl hydrocarbon receptor	13	0	0	13
chromobox protein homolog 1	17	0	0	17
peripheral myelin protein 22	18	0	0	18
cytochrome P450 3A4 isoform 1	16	0	0	16
Gamma-aminobutyric acid receptor subunit pi	16	2	1	19
ATP-binding cassette sub-family C member 3	0	25	0	25
Multidrug resistance-associated protein 4	0	25	0	27
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	2
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	21	0	0	21
Bile salt export pump	0	32	0	32
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 2	0	2	1	4
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	6	1	8
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Cytochrome P450 3A4	0	16	1	18
Cytochrome P450 2D6	0	7	1	8
Cytochrome P450 2C9	0	12	1	14
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	16	2	1	19
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	16	2	1	19
Gamma-aminobutyric acid receptor subunit gamma-2	16	2	1	19
UDP-glucuronosyltransferase 1-6	0	0	0	1
Glutamate receptor 2	21	1	0	22
Gamma-aminobutyric acid receptor subunit alpha-5	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-3	16	2	1	19
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	2
Carbonic anhydrase 4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-2	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-4	16	2	1	19
Gamma-aminobutyric acid receptor subunit gamma-3	16	2	1	19
Gamma-aminobutyric acid receptor subunit alpha-6	16	2	1	19
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Prostaglandin G/H synthase 2	0	2	2	5
Carbonic anhydrase 7	0	1	0	1
Nuclear receptor ROR-gamma	9	1	1	11
Cytochrome P450 2J2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	16	2	1	19
Gamma-aminobutyric acid receptor subunit beta-3	16	2	1	19
Gamma-aminobutyric acid receptor subunit beta-2	16	2	1	19
Carbonic anhydrase 9	0	2	0	2
GABA theta subunit	16	2	1	19
Canalicular multispecific organic anion transporter 1	0	25	0	25
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	16	2	1	19
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
toxin B	0	0	0	1
TDP1 protein	34	0	0	34
lamin isoform A-delta10	27	0	0	27
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
acetylcholinesterase	10	0	0	10
dopamine D1 receptor	4	0	0	4
15-lipoxygenase, partial	4	0	0	4
pregnane X receptor	8	0	0	8
phosphopantetheinyl transferase	13	0	0	13
USP1 protein, partial	14	0	0	14
NFKB1 protein, partial	7	0	0	7
Thrombopoietin	7	0	0	7
regulator of G-protein signaling 4	8	0	0	8
farnesoid X nuclear receptor	18	0	0	18
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
arylsulfatase A	10	0	0	10
euchromatic histone-lysine N-methyltransferase 2	22	0	0	22
Bloom syndrome protein isoform 1	11	0	0	11
D(1A) dopamine receptor	2	0	0	2
thyroid hormone receptor beta isoform a	7	0	0	7
flap endonuclease 1	8	0	0	8
geminin	29	0	0	29
survival motor neuron protein isoform d	15	0	0	15
muscarinic acetylcholine receptor M1	7	0	0	7
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	4	0	4
Guanine nucleotide-binding protein G	2	0	0	2
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
Ataxin-2	20	0	0	20
Histone deacetylase 8	0	5	0	5
Histone deacetylase 6	0	6	0	6
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
ATP-dependent phosphofructokinase	11	0	0	11
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	18	0	0	18
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	18	0	0	18
nuclear factor erythroid 2-related factor 2 isoform 2	15	0	0	15
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Cyclin-dependent kinase 1	0	1	5	6
Heat shock protein HSP 90-beta	0	3	2	7
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	10	0	0	10
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	2	4
ATPase family AAA domain-containing protein 5	16	0	0	16
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	3	3
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	3	5	8
Amine oxidase [flavin-containing] B	0	1	0	1
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	2	1	3
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	7	7
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	3	3
Adenylate kinase 2, mitochondrial	0	0	5	6
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	7	7
Adenosine deaminase-like protein	0	0	0	1
Protease	0	1	1	2
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	6	6
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
cytochrome P450 2D6	8	0	0	8
glucocerebrosidase	5	0	0	5
cytochrome P450 2D6 isoform 1	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Rap guanine nucleotide exchange factor 3	5	0	0	5
Lysosomal acid glucosylceramidase	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Chain A, HADH2 protein	15	0	0	15
Chain B, HADH2 protein	15	0	0	15
Chain A, Cruzipain	6	0	0	6
interleukin 8	6	0	0	6
peroxisome proliferator-activated receptor delta	18	0	0	18
tumor necrosis factor	2	0	0	2
vitamin D3 receptor isoform VDRA	12	0	0	12
Cytochrome P450 2C19	0	7	1	9
Potassium voltage-gated channel subfamily H member 2	0	10	0	11
Aurora kinase B	0	1	5	6
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	1	10
Replicase polyprotein 1ab	0	3	3	6
Cytochrome P450 2C8	0	3	0	4
Cytochrome P450 2B6	0	4	0	5
Chain A, Beta-lactamase	4	0	0	4
glp-1 receptor, partial	10	0	0	10
Fumarate hydratase	11	0	0	11
PPM1D protein	8	0	0	8
polyprotein	11	0	0	11
67.9K protein	10	0	0	10
Parkin	2	0	0	2
IDH1	7	0	0	7
thyroid stimulating hormone receptor	11	0	0	11
peripheral myelin protein 22 isoform 1	9	0	0	9
hemoglobin subunit beta	4	0	0	4
cellular tumor antigen p53 isoform a	7	0	0	7
huntingtin isoform 2	5	0	0	5
ras-related protein Rab-9A	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Interferon beta	21	0	0	21
Integrin beta-3	6	0	0	6
Integrin alpha-IIb	6	0	0	6
Adenosine receptor A3	0	6	0	6
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Adenosine receptor A2a	0	4	0	4
D(1A) dopamine receptor	4	0	0	4
Spike glycoprotein	16	0	3	19
Multidrug and toxin extrusion protein 1	0	3	0	3
Histone-lysine N-methyltransferase EHMT2	0	3	0	3
Chain A, Ferritin light chain	10	0	0	10
thioredoxin reductase	14	0	0	14
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
thioredoxin glutathione reductase	4	0	0	4
G	12	0	0	12
P53	1	0	0	1
Histone H2A.x	12	0	0	12
DNA polymerase iota isoform a (long)	9	0	0	9
M-phase phosphoprotein 8	5	0	0	5
muscleblind-like protein 1 isoform 1	7	0	0	7
HLA class I histocompatibility antigen, B alpha chain	12	0	0	12
Inositol hexakisphosphate kinase 1	12	0	0	12
Protein-arginine deiminase type-4	0	4	0	4
cytochrome P450 2C9, partial	12	0	0	12
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
DNA polymerase kappa isoform 1	9	0	0	9
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	3	0	0	3
Inositol monophosphatase 1	5	0	0	5
Solute carrier organic anion transporter family member 1B3	0	2	0	5
Solute carrier organic anion transporter family member 1B1	0	4	0	6
Farnesyl pyrophosphate synthase	0	1	0	1
Cysteine protease	0	2	0	2
DNA topoisomerase	0	1	0	1
putative alpha-glucosidase	1	0	0	1
alpha-galactosidase	4	0	0	4
lysosomal alpha-glucosidase preproprotein	2	0	0	2
cytochrome P450 2C19 precursor	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
nuclear receptor ROR-gamma isoform 1	11	0	0	11
relaxin receptor 1 isoform 1	2	0	0	2
lethal factor (plasmid)	5	0	0	5
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	0	6	6
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	0	0	1
DNA ligase	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	1	1	7
DNA topoisomerase 2-alpha	0	2	4	10
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Type-2 restriction enzyme HindIII	0	1	0	1
Ribonuclease pancreatic	0	1	0	1
DNA topoisomerase 2-beta	0	0	5	6
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Integrase	0	2	0	2
DNA topoisomerase type IB small subunit	0	0	1	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
cytochrome P450 2C9 precursor	3	0	0	3
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	5
DNA gyrase subunit B	0	2	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	7	0	0	7
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Macrophage metalloelastase	0	1	0	1
endonuclease IV	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Glucocorticoid receptor	0	12	3	20
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	12	0	12
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	4	0	5
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	5	6
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Luciferase	7	0	0	7
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
caspase 7, apoptosis-related cysteine protease	4	0	0	4
caspase-3	4	0	0	4
Caspase-7	4	0	0	4
runt-related transcription factor 1 isoform AML1b	1	0	0	1
caspase-3	4	0	0	4
core-binding factor subunit beta isoform 2	1	0	0	1
mitogen-activated protein kinase 1	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Transthyretin	0	1	0	1
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
ATP-dependent translocase ABCB1	0	5	1	8
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	1	0	2
Glutamate receptor 3	1	1	0	2
Glutamate receptor 4	1	1	0	2
Platelet-activating factor receptor	2	0	0	2
Multidrug resistance-associated protein 1	0	2	0	4
Reverse transcriptase/RNaseH	0	1	0	1
Lysine-specific demethylase 6B	0	2	0	2
Lysine-specific demethylase 4A	0	1	1	2
Lysine-specific demethylase 5A	0	2	0	2
Flavin reductase (NADPH)	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Ileal sodium/bile acid cotransporter	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Bile acid receptor	0	0	1	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Nitric oxide synthase, inducible	0	1	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	1	0	0	1
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	3	4
Aromatase	0	3	0	3
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B2, mitochondrial	0	2	0	2
ATP-dependent translocase ABCB1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	1	1	2
Sterol 14-alpha demethylase	0	0	3	3
Sterol 14-alpha demethylase	0	2	2	4
14-alpha sterol demethylase	0	0	3	3
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
Skn7p	0	0	0	2
nonstructural protein 1	5	0	0	5
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
serine/threonine-protein kinase PLK1	1	0	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
thyrotropin-releasing hormone receptor	3	0	0	3
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Vpr	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Epidermal growth factor receptor	0	7	7	14
Amyloid-beta precursor protein	1	1	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
acid sphingomyelinase	2	0	0	2
DNA polymerase beta	2	0	0	2
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	1	0	1
Alpha-synuclein	3	1	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Methionine aminopeptidase	0	1	0	1
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Thymidine kinase	0	1	0	1
ClpP	2	0	0	2
Solute carrier family 22 member 1	0	1	0	3
POU domain, class 2, transcription factor 2	0	0	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	0	0	2
Leukotriene C4 synthase	0	0	2	2
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
epidermal growth factor receptor isoform a precursor	1	1	0	2
tyrosine-protein kinase Yes	4	0	0	4
Bone morphogenetic protein receptor type-1B	0	0	5	5
Cell division cycle 7-related protein kinase	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	2	3
Serine/threonine-protein kinase PLK4	0	0	5	5
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	5	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Pyridoxal kinase	0	0	5	5
Citron Rho-interacting kinase	0	0	5	5
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	2
Peripheral plasma membrane protein CASK	0	0	2	2
Aurora kinase A	0	0	5	5
Cyclin-G-associated kinase	0	2	5	7
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	2	2
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 3	0	0	5	5
Mitogen-activated protein kinase 13	0	0	2	2
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	0	5	5
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	5	5
NUAK family SNF1-like kinase 1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	5	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Tyrosine-protein kinase JAK2	0	4	5	9
Rho-associated protein kinase 2	0	0	5	5
Serine/threonine-protein kinase ULK1	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	5	5
Ribosomal protein S6 kinase alpha-5	0	0	5	5
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	5	5
Ribosomal protein S6 kinase alpha-4	0	0	5	5
Serine/threonine-protein kinase 16	0	0	5	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	3	3
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	5	5
Serine/threonine-protein kinase D3	0	0	5	5
Cyclin-dependent kinase 14	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 6	0	0	5	5
Serine/threonine-protein kinase OSR1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	5	5
Serine/threonine-protein kinase LATS1	0	0	5	5
Serine/threonine-protein kinase PAK 4	0	0	5	5
Serine/threonine-protein kinase Chk2	0	0	2	2
Tyrosine-protein kinase ABL1	0	3	6	9
RAF proto-oncogene serine/threonine-protein kinase	0	1	3	5
Receptor tyrosine-protein kinase erbB-2	0	3	3	6
High affinity nerve growth factor receptor	0	0	5	5
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	5	5
Cytochrome P450 2E1	0	1	0	1
Protein kinase C beta type	0	0	5	5
Insulin receptor	0	1	5	6
Tyrosine-protein kinase Lck	0	1	5	6
Tyrosine-protein kinase Fyn	0	2	5	7
Glycogen phosphorylase, liver form	0	0	5	5
Tyrosine-protein kinase Fes/Fps	0	0	5	5
Macrophage colony-stimulating factor 1 receptor	0	1	2	3
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	1	5	6
Tyrosine-protein kinase Lyn	0	1	5	6
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	5	7
Insulin-like growth factor 1 receptor	0	0	5	5
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	5	5
Hepatocyte growth factor receptor	0	0	5	5
Tyrosine-protein kinase HCK	0	2	5	7
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Platelet-derived growth factor receptor beta	0	1	5	6
Tyrosine-protein kinase Fgr	0	1	4	5
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	1	5	6
Mast/stem cell growth factor receptor Kit	0	0	2	2
Glycogen phosphorylase, brain form	0	0	5	5
Breakpoint cluster region protein	0	1	5	6
Serine/threonine-protein kinase pim-1	0	0	5	5
Fibroblast growth factor receptor 1	0	0	5	5
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	0	5	5
ADP/ATP translocase 3	0	0	5	5
Inosine-5'-monophosphate dehydrogenase 2	0	2	5	7
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	5	5
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	2	6	9
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	5	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	5	5
Platelet-derived growth factor receptor alpha	0	0	2	2
Tyrosine-protein kinase Fer	0	0	5	5
Protein kinase C alpha type	0	0	5	5
cAMP-dependent protein kinase catalytic subunit alpha	0	0	5	5
Vascular endothelial growth factor receptor 1	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	5	5
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Casein kinase II subunit alpha'	0	0	5	5
Ras-related protein Rab-6A	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	5	5
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	2	2	4
Multifunctional protein ADE2	0	0	5	5
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	5	5
Ferrochelatase, mitochondrial	0	0	6	6
Ribosomal protein S6 kinase beta-1	0	0	5	5
Tyrosine-protein kinase JAK1	0	4	6	10
Sodium-dependent dopamine transporter	0	1	0	1
Protein kinase C eta type	0	0	2	2
Cyclin-dependent kinase 2	0	1	6	7
Beta-adrenergic receptor kinase 1	0	0	5	5
Cruzipain	0	1	0	1
Probable ATP-dependent RNA helicase DDX6	0	0	5	5
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	0	5	5
MAP/microtubule affinity-regulating kinase 3	0	0	5	5
Mitogen-activated protein kinase 1	0	1	5	6
Ephrin type-A receptor 2	0	1	5	6
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	0	5	5
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	2	6	8
UMP-CMP kinase	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	5	5
Wee1-like protein kinase	0	0	5	5
Heme oxygenase 2	0	0	5	5
Tyrosine-protein kinase receptor UFO	0	0	2	2
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	5	5
DnaJ homolog subfamily A member 1	0	0	5	5
RAC-alpha serine/threonine-protein kinase	0	0	5	5
RAC-beta serine/threonine-protein kinase	0	0	5	5
G protein-coupled receptor kinase 4	0	0	2	2
Dual specificity protein kinase TTK	0	0	4	4
DNA replication licensing factor MCM4	0	0	5	5
Type-1 angiotensin II receptor	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	0	2	2
Vascular endothelial growth factor receptor 2	0	2	2	4
Dual specificity mitogen-activated protein kinase kinase 2	0	2	5	7
Receptor-type tyrosine-protein kinase FLT3	0	2	5	7
Bone morphogenetic protein receptor type-1A	0	0	5	5
Activin receptor type-1B	0	0	5	5
TGF-beta receptor type-1	0	0	5	5
Serine/threonine-protein kinase receptor R3	0	0	3	3
TGF-beta receptor type-2	0	0	5	5
Electron transfer flavoprotein subunit beta	0	0	4	4
Tyrosine-protein kinase CSK	0	1	5	6
Glycine--tRNA ligase	0	0	5	5
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Protein kinase C iota type	0	0	5	5
Exosome RNA helicase MTR4	0	0	5	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	2	3
Serine/threonine-protein kinase mTOR	0	3	3	6
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase Tec	0	1	5	6
Tyrosine-protein kinase TXK	0	1	3	4
Tyrosine-protein kinase ABL2	0	1	5	6
Tyrosine-protein kinase FRK	0	1	5	6
G protein-coupled receptor kinase 6	0	0	4	4
Tyrosine-protein kinase ZAP-70	0	0	2	2
Tyrosine-protein kinase SYK	0	1	5	6
26S proteasome regulatory subunit 6B	0	0	5	5
Mitogen-activated protein kinase 8	0	0	5	5
Mitogen-activated protein kinase 9	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	5	5
Casein kinase I isoform alpha	0	1	4	5
Casein kinase I isoform delta	0	0	5	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	2	3
MAP kinase-activated protein kinase 2	0	0	5	5
Cyclin-dependent kinase 8	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	5	5
Cysteine--tRNA ligase, cytoplasmic	0	0	4	4
Casein kinase I isoform epsilon	0	0	5	5
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	5	5
Dual specificity protein kinase CLK1	0	0	5	5
Dual specificity protein kinase CLK2	0	0	5	5
Dual specificity protein kinase CLK3	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	5	5
Glycogen synthase kinase-3 beta	0	0	5	5
Cyclin-dependent kinase 7	0	0	5	5
Cyclin-dependent kinase 9	0	0	5	5
Ras-related protein Rab-27A	0	0	5	5
Tyrosine-protein kinase Blk	0	1	3	4
Interleukin-1 receptor-associated kinase 1	0	0	5	5
Ribosomal protein S6 kinase alpha-3	0	0	5	5
Cytoplasmic tyrosine-protein kinase BMX	0	2	3	5
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	3	3
Serine/threonine-protein kinase Nek2	0	0	5	5
Serine/threonine-protein kinase Nek3	0	0	5	5
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	4	3	7
Dual specificity mitogen-activated protein kinase kinase 6	0	0	5	5
Serine/threonine-protein kinase PLK1	0	0	5	5
Death-associated protein kinase 1	0	0	2	2
LIM domain kinase 1	0	0	5	5
LIM domain kinase 2	0	0	5	5
Mitogen-activated protein kinase 12	0	0	2	2
Mitogen-activated protein kinase 10	0	0	5	5
Tyrosine--tRNA ligase, cytoplasmic	0	0	5	5
Ephrin type-B receptor 3	0	0	5	5
Ephrin type-A receptor 5	0	0	5	5
Ephrin type-B receptor 4	0	1	5	6
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	5	5
Adenosine kinase	0	0	5	5
Beta-secretase 1	0	1	0	1
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Ras-related protein Rab-10	0	0	5	5
Cell division control protein 2 homolog	0	0	2	2
Actin-related protein 3	0	0	5	5
Actin-related protein 2	0	0	5	5
Calcium-dependent protein kinase 1	0	0	2	2
GTP-binding nuclear protein Ran	0	0	5	5
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	5	5
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	2	2
Cyclin-dependent kinase 6	0	0	5	5
Cyclin-dependent-like kinase 5	0	0	5	5
Cyclin-dependent kinase 16	0	0	5	5
Cyclin-dependent kinase 17	0	0	5	5
ATP-dependent 6-phosphofructokinase, platelet type	0	0	5	5
Synaptic vesicular amine transporter	0	1	0	1
Protein kinase C epsilon type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	1	5	6
Angiopoietin-1 receptor	0	0	2	2
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
Transcription factor p65	0	1	0	1
Protein kinase C theta type	0	0	5	5
Activin receptor type-1	0	0	5	5
Macrophage-stimulating protein receptor	0	0	5	5
Focal adhesion kinase 1	0	0	5	5
Protein kinase C zeta type	0	0	2	2
Protein kinase C delta type	0	0	5	5
Tyrosine-protein kinase BTK	0	2	6	8
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	3	3
Activated CDC42 kinase 1	0	0	5	5
Epithelial discoidin domain-containing receptor 1	0	0	5	5
Tyrosine-protein kinase ITK/TSK	0	1	3	4
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	0	5	5
Serine/threonine-protein kinase 4	0	0	5	5
Serine/threonine-protein kinase PAK 1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	5	5
Mitogen-activated protein kinase 7	0	0	5	5
Serine/threonine-protein kinase PAK 2	0	0	5	5
Serine/threonine-protein kinase 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 1	0	0	5	5
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	5	5
Rho-associated protein kinase 1	0	0	5	5
Non-receptor tyrosine-protein kinase TNK1	0	0	5	5
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	5	5
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	5	5
Activin receptor type-2B	0	0	5	5
Bone morphogenetic protein receptor type-2	0	0	5	5
Protein-tyrosine kinase 6	0	1	5	6
cGMP-dependent protein kinase 1	0	0	5	5
Cyclin-dependent kinase 13	0	0	5	5
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	5	5
Protein-tyrosine kinase 2-beta	0	0	5	5
Maternal embryonic leucine zipper kinase	0	0	5	5
Structural maintenance of chromosomes protein 1A	0	0	5	5
Chromodomain-helicase-DNA-binding protein 4	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 1	0	0	4	4
Serine/threonine-protein kinase D1	0	0	2	2
Serine/threonine-protein kinase 38	0	0	3	3
Receptor tyrosine-protein kinase erbB-4	0	2	3	5
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	3	3
Delta(24)-sterol reductase	0	0	5	5
Ribosomal protein S6 kinase alpha-1	0	1	5	6
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	5	5
Mitogen-activated protein kinase 11	0	0	5	5
Serine/threonine-protein kinase STK11	0	0	5	5
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	0	5	5
Serine/threonine-protein kinase N2	0	0	5	5
Mitogen-activated protein kinase 14	0	0	5	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	5	5
Mitogen-activated protein kinase kinase kinase 11	0	0	5	5
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	0	5	5
AP2-associated protein kinase 1	0	1	5	6
Myosin light chain kinase 3	0	0	5	5
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	5	5
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	5	5
Serine/threonine-protein kinase MRCK gamma	0	0	5	5
Acyl-CoA dehydrogenase family member 10	0	0	5	5
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	4	4
Serine/threonine-protein kinase ULK3	0	0	5	5
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Uncharacterized protein FLJ45252	0	0	5	5
Acyl-CoA dehydrogenase family member 11	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	5	5
Serine/threonine-protein kinase MARK2	0	0	5	5
Serine/threonine-protein kinase TAO1	0	0	5	5
STE20-related kinase adapter protein alpha	0	0	5	5
Myosin-14	0	0	5	5
AarF domain-containing protein kinase 1	0	0	5	5
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	3	3
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	5	5
Cyclin-dependent kinase-like 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	5	5
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Serine/threonine-protein kinase ULK2	0	0	2	2
Misshapen-like kinase 1	0	0	4	4
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	5	5
Mitogen-activated protein kinase 15	0	0	5	5
Serine/threonine-protein kinase Nek9	0	0	5	5
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	4	4
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	5	5
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	5	5
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
Calcium/calmodulin-dependent protein kinase type 1G	0	0	4	4
Serine/threonine-protein kinase Nek1	0	0	5	5
Cyclin-dependent kinase 15	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	5	5
EKC/KEOPS complex subunit TP53RK	0	0	5	5
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	5	5
Mitogen-activated protein kinase kinase kinase 5	0	0	5	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	5	5
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	5	5
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	5	5
Serine/threonine-protein kinase D2	0	0	5	5
Serine/threonine-protein kinase DCLK3	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	5	5
Serine/threonine-protein kinase SIK2	0	0	5	5
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase TAO3	0	0	5	5
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	0	2	2
dCTP pyrophosphatase 1	0	0	5	5
Dual specificity protein kinase CLK4	0	0	5	5
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
Casein kinase I isoform gamma-1	0	0	5	5
Serine/threonine-protein kinase PAK 6	0	0	3	3
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	5	5
Isoleucine--tRNA ligase, mitochondrial	0	0	3	3
BMP-2-inducible protein kinase	0	0	5	5
Obg-like ATPase 1	0	0	4	4
Midasin	0	0	5	5
Interleukin-1 receptor-associated kinase 4	0	0	5	5
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	1	5	6
Cyclin-dependent kinase 12	0	0	5	5
Serine/threonine-protein kinase PLK2	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	5	5
eIF-2-alpha kinase GCN2	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	5	5
Serine/threonine-protein kinase NLK	0	0	5	5
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	5	5
Septin-9	0	0	5	5
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	5	5
TRAF2 and NCK-interacting protein kinase	0	0	5	5
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	5	5
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
ALK tyrosine kinase receptor	0	0	2	2
SRSF protein kinase 3	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	5	5
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 2	0	0	5	5
Thyroid hormone receptor-associated protein 3	0	0	5	5
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 3	0	0	5	5
Serine/threonine-protein kinase MRCK beta	0	0	5	5
Interleukin-1 receptor-associated kinase 3	0	0	5	5
Serine/threonine-protein kinase 24	0	0	4	4
Casein kinase I isoform gamma-3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 4	0	0	5	5
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
alpha synuclein, partial	1	0	0	1
hypothetical protein, conserved	1	0	0	1
luciferase	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
histone deacetylase 9 isoform 3	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M5	0	3	0	3
Alpha-2A adrenergic receptor	0	3	0	3
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Muscarinic acetylcholine receptor M1	0	3	0	3
D(2) dopamine receptor	0	2	0	2
Androgen receptor	0	7	0	7
Alpha-1B adrenergic receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	5	0	5
Muscarinic acetylcholine receptor M3	0	3	0	3
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
Acetylcholinesterase	0	4	0	4
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 2A	0	2	0	2
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
Alpha-1A adrenergic receptor	0	4	0	4
10 kDa heat shock protein, mitochondrial	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Fatty-acid amide hydrolase 1	1	0	0	1
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Leukotriene B4 receptor 1	1	0	0	1
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
Glutamate receptor ionotropic, kainate 5	1	0	0	1
10 kDa chaperonin	0	3	0	3
Leukotriene B4 receptor 2	1	0	0	1
Histone-lysine N-methyltransferase SUV39H1	0	1	0	1
Acetolactate synthase catalytic subunit, mitochondrial	0	1	0	1
Pyruvate kinase PKM	0	1	0	1
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	1	0	1
Mycothiol S-conjugate amidase	0	1	0	1
E3 ubiquitin-protein ligase RNF31	0	1	0	1
RanBP-type and C3HC4-type zinc finger-containing protein 1	0	1	0	1
Sharpin	0	1	0	1
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	3	3
Replicase polyprotein 1ab	0	0	3	3
Transmembrane protease serine 2	0	0	3	3
Procathepsin L	0	0	3	3
Replicase polyprotein 1a	0	0	3	3
Replicase polyprotein 1ab	0	0	3	3
Replicase polyprotein 1ab	0	1	3	4
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	3	3
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Eukaryotic translation initiation factor 5B	0	0	2	2
Myosin-10	0	0	4	4
Oxysterols receptor LXR-beta	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Trp operon repressor	0	0	1	1
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 3	0	2	0	2
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Liver carboxylesterase 1	0	0	0	2
Multidrug and toxin extrusion protein 2	0	1	0	1
GALC protein	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	0	0	1
Tumor necrosis factor	0	2	0	2
Neuraminidase	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Hydroxyacid oxidase 1	0	1	0	1
large T antigen	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
DNA polymerase eta isoform 1	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
streptokinase A precursor	0	0	2	2
Trypsin	0	0	0	1
Albumin	0	0	1	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Photosystem I iron-sulfur center	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Putative nucleoside diphosphate kinase	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
G1/S-specific cyclin-E1	0	1	0	1
Choline-phosphate cytidylyltransferase A	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	1	1
Rab-like protein 3	0	0	2	2
Sigma intracellular receptor 2	0	1	0	1
ATP-dependent RNA helicase DHX30	0	0	2	2
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Peroxiredoxin-like 2A	0	1	0	1
Platelet glycoprotein VI	0	1	0	1
vasopressin V1b receptor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cholinesterase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A2b	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chitotriosidase-1	0	2	1	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Endochitinase B1	0	2	1	3
Beta-lactamase	0	1	0	2
Beta-lactamase	0	2	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Beta-lactamase SHV-1	0	1	0	2
Beta-lactamase SHV-1	0	2	0	3
Beta-lactamase	0	1	0	2
Beta-lactamase OXA-7	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	2
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	3
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	0	0	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Pirin	0	1	0	1
GTPase KRas	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Heat shock factor protein 1	0	1	0	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Serine/threonine-protein kinase ATR	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	2	2
Sterol 14-alpha-demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	3	0	3
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	2	1	3
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	3	2	5
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	3	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
NS5	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Corticotropin releasing hormone receptor 2	0	1	0	1
Lysine-specific demethylase 4B	0	1	0	1
ATP-dependent molecular chaperone HSP82	0	1	0	1
Heat shock protein HSP 90-alpha	0	3	2	5
Cholesteryl ester transfer protein	0	0	1	1
ATP-dependent molecular chaperone HSC82	0	1	0	1
Endoplasmin	0	1	1	2
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
Heat-shock protein	0	1	0	1
Putative heat shock protein HSP 90-alpha A4	0	1	0	1
Lysine-specific demethylase 4C	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	2	0	3
Beta-lactamase OXA-1	0	1	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase L1 type 3	0	1	0	1
Beta-lactamase TEM	0	2	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose	0	1	0	1
Trehalose-phosphatase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Alpha-1D adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Allergic Bronchopulmonary Mycosis

Synonyms(4)

Research Excerpts

Overview

Context

Treatment

Research

Studies (573)

Protein Targets (1,376)

Allergic Bronchopulmonary Mycosis

Synonyms(4)

Research Excerpts

Overview

Context

Treatment

Research

Studies (573)

Drugs Studied (142)

Protein Targets (1,376)