Coxa Plana

A particular type of FEMUR HEAD NECROSIS occurring in children, mainly male, with a course of four years or so.

Synonym
Perthes Disease
Legg-Calve-Perthes Disease
Osteochondritis Deformans
Coxa Plana
Legg-Calvu00E9-Perthes Disease
Legg-Calvu00E9-Perthes Syndrome
Legg-Perthes Disease
Legg-Calve-Perthes Syndrome

Excerpt	Reference
"Legg-Perthes disease is a pediatric hip disorder characterized by avascular necrosis of the femoral head."	( Austin, H; Dilley, A; Eldridge, J; Evatt, B; Hooper, WC; Jamil, M; Miller, C; Stokes, M, 2003)
"Legg-Calvé-Perthes disease is a juvenile form of idiopathic osteonecrosis of the femoral head that can lead to permanent femoral head deformity and premature osteoarthritis."	( Kim, HK, 2012)
"Legg-Calve-Perthes disease is a paediatric condition encompassing idiopathic osteonecrosis of the femoral head (ONFH)."	( Cantrill, LC; Carpenter, C; Cheng, TL; Little, DG; Mikulec, K; Murphy, CM; Schindeler, A, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	68 (46.58)	23.3326
1990's	23 (15.75)	12.5806
2000's	22 (15.07)	18.1394
2010's	28 (19.18)	28.8240
2020's	5 (3.42)	9.53

Drug	Relationship Strength	Studies	Trials
iodine	low	1	0
methanol	low	1	0
acetaminophen	low	1	0
diclofenac	low	1	0
fentanyl	low	1	0
midazolam	low	1	0
pamidronate	low	1	0
prednisolone	low	1	0
thyroxine	low	1	0
prednisone	low	1	0
penicillin g	low	1	0
sucrose	low	1	0
levodopa	low	1	0
methylprednisolone	low	1	0
diatrizoate meglumine	low	1	0
meglumine	low	3	0
iodinated glycerol	low	1	0
manganese	medium	2	1
technetium	low	32	0
gadolinium	low	7	0
trolamine salicylate	low	27	0
atracurium	low	1	0
ibandronic acid	low	1	0
caloreen	medium	1	1
iopamidol	low	1	0
fluorodeoxyglucose f18	low	1	0
zoledronic acid	low	4	0
nsc-172755	low	1	0
fibrinogen	low	2	0
homocysteine	low	1	0
deoxypyridinoline	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	3	0
technetium tc 99m (sn)methylenediphosphonate	low	1	0
technetium tc 99m n-(methylamino)methylene diphosphonate	low	1	0
atropine	low	1	0
organophosphonates	low	2	0
cortisone	low	2	0
glucosamine	low	1	0
pyrophosphate	low	4	0
thiopental	low	1	0
osteoprotegerin	low	1	0
phenylephrine hydrochloride	low	4	0
iloprost	low	1	0
aluminum	low	1	0
cefotaxime	low	1	0
technetium tc 99m pyrophosphate	low	3	0
gadolinium dtpa	low	5	0
amoxicillin-potassium clavulanate combination	low	1	0
technetium tc 99m diphosphonate	low	5	0
aluminum oxide	low	1	0
sodium pertechnetate tc 99m	low	1	0
chlortetracycline	low	1	0
transforming growth factor beta	low	1	0
technetium tc 99m medronate	low	17	0
thromboplastin	low	1	0
chondroitin sulfates	low	1	0
rifampin	low	1	0
alcian blue	low	1	0
leptin	low	1	0

Protein Targets (507)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	8	0	0	8
ATAD5 protein, partial	1	0	0	1
GLS protein	4	0	0	4
Microtubule-associated protein tau	2	0	0	2
Smad3	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
thyroid stimulating hormone receptor	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	4	0	0	4
progesterone receptor	7	0	0	7
EWS/FLI fusion protein	5	0	0	5
retinoic acid nuclear receptor alpha variant 1	7	0	0	7
retinoid X nuclear receptor alpha	8	0	0	8
estrogen-related nuclear receptor alpha	9	0	0	9
estrogen nuclear receptor alpha	18	0	0	18
peroxisome proliferator activated receptor gamma	7	0	0	7
aryl hydrocarbon receptor	5	0	0	5
chromobox protein homolog 1	6	0	0	6
thyroid hormone receptor beta isoform 2	6	0	0	6
peripheral myelin protein 22	7	0	0	7
cytochrome P450 3A4 isoform 1	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	2	2	1	5
ATP-binding cassette sub-family C member 3	0	8	0	8
Multidrug resistance-associated protein 4	0	8	0	8
Solute carrier family 22 member 6	0	4	0	4
Carbonic anhydrase 12	0	2	0	3
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	3	0	0	3
Bile salt export pump	0	13	0	13
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	6	0	7
Carbonic anhydrase 2	0	7	1	9
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	0	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Carbonic anhydrase 3	0	1	0	2
Cytochrome P450 3A4	0	3	0	3
Cytochrome P450 2D6	0	1	0	1
Cytochrome P450 2C9	0	3	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	2	2	1	5
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	2	2	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	2	2	1	5
UDP-glucuronosyltransferase 1-6	0	3	0	4
Glutamate receptor 2	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	2	2	1	5
Gamma-aminobutyric acid receptor subunit alpha-3	2	2	1	5
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	4	0	5
Carbonic anhydrase 4	0	1	0	2
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	1	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	2	2	1	5
Gamma-aminobutyric acid receptor subunit alpha-2	2	2	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	2	2	1	5
Gamma-aminobutyric acid receptor subunit gamma-3	2	2	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	2	2	1	5
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Prostaglandin G/H synthase 2	0	4	0	5
Carbonic anhydrase 7	0	1	0	2
Nuclear receptor ROR-gamma	3	0	0	3
Cytochrome P450 2J2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	2	3	1	6
Gamma-aminobutyric acid receptor subunit beta-3	2	2	1	5
Gamma-aminobutyric acid receptor subunit beta-2	2	2	1	5
Carbonic anhydrase 9	0	4	1	6
GABA theta subunit	2	2	1	5
Canalicular multispecific organic anion transporter 1	0	8	0	8
Carbonic anhydrase 15	0	1	0	2
Carbonic anhydrase 13	0	1	0	2
Gamma-aminobutyric acid receptor subunit epsilon	2	2	1	5
Carbonic anhydrase 14	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
toxin B	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	2	0	0	2
thioredoxin reductase	6	0	0	6
AR protein	13	0	0	13
hypothetical protein, conserved	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
glucocorticoid receptor [Homo sapiens]	14	0	0	14
cytochrome P450 2D6	1	0	0	1
glucocerebrosidase	2	0	0	2
peroxisome proliferator-activated receptor delta	5	0	0	5
Rac1 protein	0	0	1	1
IDH1	3	0	0	3
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
euchromatic histone-lysine N-methyltransferase 2	9	0	0	9
Bloom syndrome protein isoform 1	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
DNA polymerase kappa isoform 1	3	0	0	3
muscarinic acetylcholine receptor M1	3	0	0	3
lethal factor (plasmid)	1	0	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Fatty acid-binding protein, liver	0	3	0	3
Integrin beta-3	0	1	0	1
Myeloperoxidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	1	0	1
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	1	1	2
NPYLR7B	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
GLI family zinc finger 3	7	0	0	7
pregnane X nuclear receptor	11	0	0	11
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	1	0	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	1	6
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M1	0	2	1	5
Muscarinic acetylcholine receptor M3	0	2	1	5
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M2	0	2	1	6
Muscarinic acetylcholine receptor M1	0	2	1	6
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	2	1	5
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	1	0	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
Albumin	0	1	3	4
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
Kappa-type opioid receptor	0	2	0	4
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Metallo-beta-lactamase VIM-13	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	1	0	1
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	2
Solute carrier family 22 member 11	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Beta-lactamase VIM-1	0	0	0	2
Solute carrier family 22 member 7	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
endonuclease IV	1	0	0	1
dopamine D1 receptor	2	0	0	2
pregnane X receptor	2	0	0	2
TDP1 protein	7	0	0	7
regulator of G-protein signaling 4	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	2	0	0	2
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
peripheral myelin protein 22 isoform 1	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
heat shock protein beta-1	1	0	0	1
flap endonuclease 1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
geminin	8	0	0	8
survival motor neuron protein isoform d	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
Glucocorticoid receptor	0	8	2	15
Sex hormone-binding globulin	0	0	1	1
Glycine receptor subunit alpha-1	0	8	0	8
Corticosteroid-binding globulin	0	2	0	2
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	1	0	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Hsf1 protein	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Transthyretin	0	1	1	6
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Luciferase	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
ATP-dependent translocase ABCB1	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	2	1	3
D(3) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
activating transcription factor 6	3	0	0	3
thyroid hormone receptor beta isoform a	3	0	0	3
lamin isoform A-delta10	8	0	0	8
Cellular tumor antigen p53	6	0	0	6
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	4	0	5
Farnesyl pyrophosphate synthase	0	6	0	6
Prostaglandin E2 receptor EP1 subtype	0	0	1	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	0	1	1
Prostacyclin receptor	0	2	1	3
Prostacyclin receptor	0	1	1	2
Spike glycoprotein	3	0	0	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Prostaglandin D2 receptor	0	0	1	1
acetylcholinesterase	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
histone deacetylase 9 isoform 3	1	0	0	1
USP1 protein, partial	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
15-lipoxygenase, partial	2	0	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
phosphopantetheinyl transferase	1	0	0	1
apical membrane antigen 1, AMA1	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
arylsulfatase A	1	0	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
importin subunit beta-1 isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
snurportin-1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
Polyphenol oxidase 2	0	0	0	1
Plasma kallikrein	0	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Tyrosinase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Carbonic anhydrase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
phosphoglycerate kinase	1	0	0	1
ATP-dependent phosphofructokinase	2	0	0	2
PPM1D protein	1	0	0	1
nonstructural protein 1	1	0	0	1
G	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
muscleblind-like protein 1 isoform 1	2	0	0	2
Interferon beta	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Androgen receptor	0	3	0	3
Inositol hexakisphosphate kinase 1	2	0	0	2
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
cytochrome P450 2C9, partial	2	0	0	2
ATP-dependent translocase ABCB1	0	1	0	1
Translocator protein	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	3	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
streptokinase A precursor	0	0	1	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Guanine nucleotide-binding protein G	1	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
glp-1 receptor, partial	2	0	0	2
GALC protein	1	0	0	1
thyroid stimulating hormone receptor	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	3	0	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
thioredoxin glutathione reductase	1	0	0	1
estrogen receptor 2 (ER beta)	1	0	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
nuclear receptor ROR-gamma isoform 1	1	0	0	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Chain A, Cruzipain	1	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	3
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	5
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Chain A, Ferritin light chain	1	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
serine/threonine-protein kinase PLK1	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
farnesoid X nuclear receptor	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Prothrombin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Adenosine receptor A1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Fumarate hydratase	1	0	0	1
polyprotein	1	0	0	1
Butyrophilin subfamily 3 member A1	0	0	1	2
72 kDa type IV collagenase	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(8)

Research Excerpts

Overview

Research

Studies (146)

Protein Targets (507)

Coxa Plana

Synonyms(8)

Research Excerpts

Overview

Research

Studies (146)

Drugs Studied (73)

Protein Targets (507)