Fasciitis, Plantar

Inflammation of the plantar fascia (APONEUROSIS) on the bottom of the foot causing heel pain. The etiology of plantar fasciitis remains controversial but is likely to involve a biomechanical imbalance. Though often presenting along with HEEL SPUR, they do not appear to be causally related.

Synonym
Fasciitis, Plantar

Excerpt	Reference
"Plantar fasciitis is a relatively common disorder of the foot, yet little is known about its prevalence, what types of physicians see patients with the disorder, or how, on a national scale, patients are typically managed."	( Riddle, DL; Schappert, SM, 2004)
"Plantar fasciitis is a common cause of foot pain and may be disabling."	( Emmett, L; Fogelman, I; Frater, C; Halasz, P; Perera, C; Van der Wall, H; Vu, D, 2006)
"Plantar fasciitis is the most common cause of plantar heel pain."	( Atkins, KL; Chin, KF; Nairn, DS; Noorani, AM, 2010)
"Plantar fasciitis is commonly treated with corticosteroid injections to decrease pain and inflammation."	( Cashdollar, MR; Catanzariti, AR; Fuge, L; Kim, C; Mendicino, RW, 2010)
"Plantar fasciitis is a common cause of heel pain."	( Ball, EM; Benson, C; Burns, J; Foo, J; McKeeman, HM; Moore, OA; Patterson, C; Taggart, AJ; Wright, GD; Yau, WH, 2013)
"Plantar fasciitis is one of the most common causes of foot pain in adults."	( Ceylan, MF; Gökalp, MA; Guner, S; Guner, SI; Keskin, S; Onder, H, 2013)
"Chronic plantar fasciitis is a common orthopedic condition that can prove difficult to successfully treat."	( Monto, RR, 2014)
"Plantar fasciitis is one of the commonest, and most frustrating, foot ailments seen in a regular orthopaedic clinic."	( Dhillon, M; Hegde, C; Jagtap, P; Shetty, S; Shetty, VD, 2014)
"Plantar fasciitis is a common cause of heel pain."	( Badiei, S; Baradaran Mahdavi, S; Hoseinzadeh, B; Rastegar, S, 2018)
"Plantar fasciitis is one of the most common causes of heel pain."	( Jain, SK; Kearns, SR; Kumar, S; Suprashant, K; Yadav, A, 2018)
"Plantar fasciitis is one of the most common clinical presentations seen by podiatric clinicians today."	( Boumendjel, Y; Grady, J; LaViolette, K; Smolinski, T, 2019)
"Plantar fasciitis is a frequent and painful condition with a lifetime incidence of 10%."	( Herzog, R; Johannsen, F; Konradsen, L; Krogsgaard, MR, 2020)
"Plantar fasciitis is a common cause of heel pain that affects the quality of life of many people."	( Chen, HC; Chiang, MT; Chin, YPH; Hong, YH; Lai, WF; Song, W; Yoon, CH, 2021)
"Plantar fasciitis is a recurrent cause of heel pain and is often treated by corticosteroid infections (CSI)."	( Bedi, H; Bulloch, G; Gibson, D; Lower, K; Rastogi, A; Rodwell, A; Seth, I; Seth, N, 2023)

Excerpt	Reference
"The treatment of plantar fasciitis has dramatically improved in the past decade with minimally invasive techniques becoming increasingly available."	( Al-Boloushi, Z; Arian, M; Gómez-Trullén, EM; Herrero, P; López-Royo, MP, 2019)

Excerpt	Reference
"Frequently, the initial treatment for plantar fasciitis is targeted at increasing dorsiflexion range of motion by stretching the gastroc-soleus musculature."	( Garrett, TR; Neibert, PJ, 2013)
"Specialized treatment of plantar fasciitis that can reduce inflammation and promote healing may be a possible alternative prior to surgical intervention."	( Andrews, J; Poka, A; Zelen, CM, 2013)
"We found that the treatment of plantar fasciitis with steroid or PRP injection was equally effective."	( Jain, SK; Kearns, SR; Kumar, S; Suprashant, K; Yadav, A, 2018)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	20 (22.99)	18.1394
2010's	46 (52.87)	28.8240
2020's	21 (24.14)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	medium	1	1
salicylic acid	low	1	0
celecoxib	medium	2	2
diclofenac	medium	1	1
flufenamic acid	low	1	0
lidocaine	medium	10	3
khellin	low	1	0
midazolam	low	1	0
prilocaine	medium	1	1
procaine	low	1	0
hydrocortisone acetate	low	1	0
prednisolone	medium	1	1
methylprednisolone acetate	medium	3	3
glutamine	low	1	0
leucine	low	1	0
methionine	low	1	0
arginine	low	1	0
triamcinolone acetonide	low	3	0
thiazoles	low	1	0
dexamethasone 21-phosphate	medium	2	1
betamethasone	medium	2	1
evernic acid	medium	1	1
dexamethasone isonicotinate	medium	2	1
triamcinolone hexacetonide	low	1	0
tantalum	low	1	0
calcium pyrophosphate	low	1	0
ozone	medium	3	1
trolamine salicylate	low	1	0
triamcinolone	medium	4	2
trazodone hydrochloride	medium	1	1
betamethasone sodium phosphate	medium	1	1
delphinidin	medium	1	1
levobupivacaine	low	1	0
betamethasone-17,21-dipropionate	medium	1	1
cortisone	medium	2	1
microlenin	medium	1	1
zithromax	low	2	0
sesquiterpenes	medium	1	1
piroxicam	medium	2	1
mobic	low	1	0
mobiflex	medium	2	1
technetium tc 99m medronate	low	1	0

Protein Targets (505)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
estrogen nuclear receptor alpha	17	0	0	17
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	0	1	1
Tyrosine-protein kinase Fyn	0	0	1	1
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
thioredoxin reductase	10	0	0	10
phosphopantetheinyl transferase	3	0	0	3
NFKB1 protein, partial	3	0	0	3
GLS protein	7	0	0	7
thyroid stimulating hormone receptor	6	0	0	6
alpha-galactosidase	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	13	0	0	13
cytochrome P450 2C19 precursor	3	0	0	3
chromobox protein homolog 1	10	0	0	10
flap endonuclease 1	5	0	0	5
DNA polymerase iota isoform a (long)	1	0	0	1
muscarinic acetylcholine receptor M1	5	0	0	5
lethal factor (plasmid)	1	0	0	1
Cytochrome P450 3A4	0	5	0	6
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	4	0	0	4
pregnane X receptor	3	0	0	3
GLI family zinc finger 3	13	0	0	13
AR protein	15	0	0	15
progesterone receptor	11	0	0	11
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
glucocorticoid receptor [Homo sapiens]	13	0	0	13
estrogen-related nuclear receptor alpha	11	0	0	11
farnesoid X nuclear receptor	4	0	0	4
pregnane X nuclear receptor	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
IDH1	7	0	0	7
aryl hydrocarbon receptor	7	0	0	7
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
thyroid hormone receptor beta isoform a	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
ATP-binding cassette sub-family C member 3	0	11	0	11
Multidrug resistance-associated protein 4	0	11	0	11
Voltage-dependent calcium channel gamma-2 subunit	5	0	0	5
Bile salt export pump	0	16	0	16
Glucocorticoid receptor	0	12	1	18
Glycine receptor subunit alpha-1	0	12	0	12
Glutamate receptor 2	5	0	0	5
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Canalicular multispecific organic anion transporter 1	0	9	0	9
ORF73	0	0	1	1
peroxisome proliferator activated receptor gamma	5	0	0	5
thyroid hormone receptor beta isoform 2	5	0	0	5
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	2	3
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Cruzipain	1	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
glp-1 receptor, partial	4	0	0	4
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
RAR-related orphan receptor gamma	11	0	0	11
SMAD family member 2	4	0	0	4
USP1 protein, partial	3	0	0	3
PPM1D protein	3	0	0	3
SMAD family member 3	4	0	0	4
TDP1 protein	13	0	0	13
Smad3	2	0	0	2
caspase 7, apoptosis-related cysteine protease	1	0	0	1
estrogen receptor 2 (ER beta)	3	0	0	3
EWS/FLI fusion protein	3	0	0	3
retinoic acid nuclear receptor alpha variant 1	8	0	0	8
retinoid X nuclear receptor alpha	9	0	0	9
G	7	0	0	7
cytochrome P450 2D6	6	0	0	6
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
67.9K protein	3	0	0	3
peroxisome proliferator-activated receptor delta	6	0	0	6
Carbonic anhydrase	0	1	0	1
Rac1 protein	0	0	1	1
caspase-3	1	0	0	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
thyroid stimulating hormone receptor	2	0	0	2
activating transcription factor 6	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
Histone H2A.x	2	0	0	2
Caspase-7	1	0	0	1
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
caspase-3	1	0	0	1
heat shock protein beta-1	5	0	0	5
geminin	17	0	0	17
peripheral myelin protein 22	5	0	0	5
cytochrome P450 3A4 isoform 1	8	0	0	8
lamin isoform A-delta10	8	0	0	8
Gamma-aminobutyric acid receptor subunit pi	8	1	0	9
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	1	0	1
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Carbonic anhydrase 12	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	3	0	3
Carbonic anhydrase 1	0	5	0	6
Carbonic anhydrase 2	0	5	0	6
Interferon beta	10	0	0	10
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
Cellular tumor antigen p53	5	0	0	5
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 3	0	2	0	2
Procathepsin L	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Adenosine receptor A3	0	2	0	2
Cytochrome P450 2D6	0	3	0	3
Cytochrome P450 2C9	0	8	0	9
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Beta-3 adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	8	1	0	9
Alpha-1B adrenergic receptor	0	3	0	3
Calpain-2 catalytic subunit	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	8	1	0	9
Gamma-aminobutyric acid receptor subunit gamma-2	8	1	0	9
5-hydroxytryptamine receptor 1A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	8	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-3	8	1	0	9
D(1A) dopamine receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 4	0	2	0	2
Prostaglandin G/H synthase 1	0	7	0	8
Carbonic anhydrase 6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	8	1	0	9
Gamma-aminobutyric acid receptor subunit alpha-2	8	1	0	9
Sodium-dependent noradrenaline transporter	0	2	0	2
Adenosine receptor A1	0	1	0	1
Cruzipain	0	1	0	1
Sodium/hydrogen exchanger 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	8	1	0	9
Gamma-aminobutyric acid receptor subunit gamma-3	8	1	0	9
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	8	1	0	9
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	1	1	2
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	8	1	10
Prostaglandin G/H synthase 2	0	3	0	3
Carbonic anhydrase	0	1	0	1
Alpha-1A adrenergic receptor	0	3	0	3
Carbonic anhydrase 7	0	2	0	2
Urotensin-2 receptor	0	1	0	1
Nuclear receptor ROR-gamma	2	0	0	2
Carbonic anhydrase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
D(2) dopamine receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	8	2	0	10
Gamma-aminobutyric acid receptor subunit beta-3	8	1	0	9
Gamma-aminobutyric acid receptor subunit beta-2	8	1	0	9
Prostaglandin G/H synthase 2	0	3	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Histone deacetylase 1	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Carbonic anhydrase 9	0	4	0	4
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Rap guanine nucleotide exchange factor 4	2	0	0	2
GABA theta subunit	8	1	0	9
Inositol hexakisphosphate kinase 1	7	0	0	7
Histone deacetylase 2	0	1	0	1
Carbonic anhydrase 4	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	6	0	0	6
Carbonic anhydrase 15	0	2	0	2
Histone deacetylase 8	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	8	1	0	9
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Carbonic anhydrase 14	0	2	0	2
Histone deacetylase 5	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
cytochrome P450 2C9, partial	7	0	0	7
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
endonuclease IV	1	0	0	1
dopamine D1 receptor	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
regulator of G-protein signaling 4	1	0	0	1
peripheral myelin protein 22 isoform 1	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
survival motor neuron protein isoform d	4	0	0	4
M-phase phosphoprotein 8	1	0	0	1
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	3	0	3
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	7	0	0	7
Multidrug and toxin extrusion protein 1	0	3	0	3
Epidermal growth factor receptor	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Alpha-synuclein	3	1	0	4
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
Aldo-keto reductase family 1 member B10	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Transthyretin	0	1	2	5
Albumin	0	2	2	4
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	2	0	2
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1-6	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Cytochrome P450 2J2	0	5	0	5
Solute carrier family 22 member 6	0	4	0	4
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Luciferase	6	0	0	6
nonstructural protein 1	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
DNA polymerase beta	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Chain A, PROTEIN (TRANSTHYRETIN)	0	0	1	1
Chain B, PROTEIN (TRANSTHYRETIN)	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, Ferritin light chain	2	0	0	2
thioredoxin glutathione reductase	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
glucocerebrosidase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cytochrome P450 2C9 precursor	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
vitamin D3 receptor isoform VDRA	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
nuclear receptor ROR-gamma isoform 1	3	0	0	3
muscleblind-like protein 1 isoform 1	4	0	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Androgen receptor	0	3	1	4
Aldo-keto reductase family 1 member C4	0	1	0	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Transcription factor SOX-18	0	1	0	1
Histamine H2 receptor	3	0	0	3
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
Transcriptional enhancer factor TEF-3	0	1	1	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Potassium channel subfamily K member 18	0	1	1	2
Acid-sensing ion channel 5	0	0	1	1
Chain A, Glutamine Binding Protein	0	0	1	1
15-lipoxygenase, partial	2	0	0	2
arylsulfatase A	4	0	0	4
Bloom syndrome protein isoform 1	3	0	0	3
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Amino acid transporter	0	1	0	1
Chain A, Beta-lactamase	4	0	0	4
ATAD5 protein, partial	5	0	0	5
transcriptional regulator ERG isoform 3	1	0	0	1
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
GALC protein	1	0	0	1
cytochrome P450 2D6 isoform 1	4	0	0	4
mitogen-activated protein kinase 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1A2	0	2	0	2
Cytochrome P450 2C19	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	1	0	1
Inositol monophosphatase 1	1	0	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Microtubule-associated protein tau	1	0	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
acetylcholinesterase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Solute carrier family 22 member 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Translocator protein	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Glutathione reductase, mitochondrial	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
lysosomal alpha-glucosidase preproprotein	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Spike glycoprotein	1	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Parkin	1	0	0	1
Solute carrier family 22 member 6	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Solute carrier family 22 member 11	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Bile salt export pump	0	1	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
acid sphingomyelinase	1	0	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Transporter	0	1	0	1
interleukin 8	1	0	0	1
streptokinase A precursor	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein-arginine deiminase type-4	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (87)

Protein Targets (505)

Fasciitis, Plantar

Synonyms(1)

Research Excerpts

Overview

Context

Treatment

Research

Studies (87)

Drugs Studied (53)

Protein Targets (505)