Page last updated: 2024-09-27

Atypical Hemolytic Uremic Syndrome

An hereditary hemolytic uremic syndrome associated with variations in the gene that encodes COMPLEMENT FACTOR H, or the related proteins CFHR1 and CFHR3. Disease often progresses to CHRONIC KIDNEY FAILURE without the prodromal symptoms of ENTEROCOLITIS and DIARRHEA that characterize typical hemolytic uremic syndrome.

Synonyms(1)

Synonym
Atypical Hemolytic Uremic Syndrome

Research Excerpts

Treatment

ExcerptReference
"New agents for the treatment of the atypical hemolytic uremic syndrome are also in development."( Francis, JM; Reddy, YN; Siedlecki, AM, 2017)

Research

Studies (80)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's53 (66.25)28.8240
2020's27 (33.75)9.53
DrugIndicatedRelationship StrengthStudiesTrials
benzoic acid0low10
methylmalonic acid0low20
creatine0low10
fluorouracil0low10
midazolam0low10
prednisolone0low30
prednisone0low40
methylprednisolone0low30
hexylamine0low10
pyrazines0low10
calcium gluconate0low10
malondialdehyde0low10
adenosine diphosphate ribose0medium11
amoxicillin0low10
pirfenidone0low10
glucose, (beta-d)-isomer0low30
oseltamivir0low10
fibrinogen0low70
homocysteine0low20
glycerophosphoinositol 4,5-bisphosphate0low10
proline0low10
docetaxel anhydrous0low10
bortezomib0low10
n-acetylneuraminic acid0low20
fibrin0low10
tacrolimus0low60
mycophenolic acid0low80
sodium bicarbonate0low10
dinoprostone0low10
sirolimus0low10
carfilzomib0low20
indocyanine green0low10
cardiovascular agents0low10
compstatin0low10
hydroxocobalamin0low10
heme0low30
heparitin sulfate0low20
vitamin b 120low50
cyclosporine0low10
eye0low30

Protein Targets (697)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
TDP1 protein110011
Transient receptor potential cation channel subfamily M member 20011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, Beta-lactamase2002
Chain A, 2-oxoglutarate Oxygenase3003
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
AR protein120012
apical membrane antigen 1, AMA11001
estrogen nuclear receptor alpha130013
Beta-lactamase 0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)1001
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
DNA polymerase kappa isoform 12002
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40708
Bile salt export pump0101
Bile salt export pump010010
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Cytochrome P450 2C9 0303
Beta-lactamase0001
Kappa-type opioid receptor0102
Solute carrier family 15 member 10101
Solute carrier family 15 member 10101
Cytochrome P450 2J20202
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Canalicular multispecific organic anion transporter 10707
Chain A, Oxygen-insensitive Nad(p)h Nitroreductase0101
Chain B, Oxygen-insensitive Nad(p)h Nitroreductase0101
Luciferase2002
acetylcholinesterase5005
GLI family zinc finger 3100010
thyroid stimulating hormone receptor3003
estrogen receptor 2 (ER beta)6006
nuclear receptor subfamily 1, group I, member 37007
estrogen-related nuclear receptor alpha110011
lethal factor (plasmid)3003
Polyphenol oxidase 20101
D-amino-acid oxidase0011
Cellular tumor antigen p53100010
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit beta-20101
Tyrosinase0101
D-amino-acid oxidase0213
Metabotropic glutamate receptor 50011
Alpha-glucosidase MAL120101
Monocarboxylate transporter 10001
Beta-lactamase 0112
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
D-aspartate oxidase0101
Serine racemase0101
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110202
RAR-related orphan receptor gamma5005
Fumarate hydratase2002
PPM1D protein4004
caspase 7, apoptosis-related cysteine protease3003
progesterone receptor7007
cytochrome P450 family 3 subfamily A polypeptide 44004
EWS/FLI fusion protein4004
glucocorticoid receptor [Homo sapiens]110011
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha6006
farnesoid X nuclear receptor6006
pregnane X nuclear receptor7007
polyprotein2002
peroxisome proliferator-activated receptor delta4004
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
caspase-33003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
nuclear receptor subfamily 1, group I, member 24004
Histone H2A.x3003
Caspase-72002
caspase-32002
thyroid hormone receptor beta isoform 28008
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 17007
26S proteasome non-ATPase regulatory subunit 110202
26S proteasome non-ATPase regulatory subunit 120202
26S proteasome non-ATPase regulatory subunit 140202
Proteasome subunit alpha type-70202
Histone deacetylase 30101
26S proteasome non-ATPase regulatory subunit 30202
Carbonic anhydrase 120101
Voltage-dependent calcium channel gamma-2 subunit5005
Prothrombin0101
Chymotrypsinogen A0101
Carbonic anhydrase 10202
Carbonic anhydrase 20202
Interferon beta5005
Carbonic anhydrase 30101
Cathepsin B0202
Neutrophil elastase0101
Cathepsin G0303
Lysosomal protective protein0202
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0202
Glutamate receptor 25106
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10203
Carbonic anhydrase 40202
Carbonic anhydrase 60101
Chymase0101
Proteasome subunit alpha type-10202
Proteasome subunit alpha type-20202
Proteasome subunit alpha type-30202
Proteasome subunit alpha type-40202
Proteasome subunit beta type-80202
Proteasome subunit beta type-80101
Proteasome subunit beta type-90202
Proteasome subunit alpha type-50202
Proteasome subunit beta type-40202
Proteasome subunit beta type-60202
Proteasome subunit beta type-50304
Carbonic anhydrase 5A, mitochondrial0202
26S proteasome regulatory subunit 70202
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100202
Carbonic anhydrase 70101
26S proteasome regulatory subunit 6B0213
26S proteasome non-ATPase regulatory subunit 80202
Proteasome subunit beta type-30202
Proteasome subunit beta type-20203
26S proteasome non-ATPase regulatory subunit 70202
26S proteasome non-ATPase regulatory subunit 40202
26S proteasome complex subunit SEM10202
Proteasome subunit alpha type-60202
26S proteasome regulatory subunit 40202
26S proteasome regulatory subunit 80202
26S proteasome regulatory subunit 10B0202
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20202
Histone deacetylase 10101
26S proteasome non-ATPase regulatory subunit 60202
Proteasomal ubiquitin receptor ADRM10202
Carbonic anhydrase 90202
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80202
Histone deacetylase 20101
ATPase family AAA domain-containing protein 58008
Proteasome subunit beta type-70202
26S proteasome non-ATPase regulatory subunit 10202
Ataxin-28008
Carbonic anhydrase 150101
Histone deacetylase 80101
Histone deacetylase 60101
Carbonic anhydrase 140101
26S proteasome non-ATPase regulatory subunit 130202
Carbonic anhydrase 5B, mitochondrial0202
Proteasome subunit beta type-20101
Proteasome subunit beta type-10101
Spike glycoprotein4004
Glutathione S-transferase omega-10101
Potassium voltage-gated channel subfamily H member 20101
Complement factor B0101
Complement C30101
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10202
Chain A, Cruzipain1001
SMAD family member 22002
SMAD family member 32002
regulator of G-protein signaling 42002
thyroid stimulating hormone receptor2002
activating transcription factor 62002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
prostaglandin E2 receptor EP2 subtype1001
vitamin D3 receptor isoform VDRA2002
mitogen-activated protein kinase 11001
geminin9009
peripheral myelin protein 225005
Solute carrier family 22 member 20001
Solute carrier family 22 member 1 0203
Solute carrier organic anion transporter family member 1A50001
Cytochrome P450 3A40314
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 60001
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 80001
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110001
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70001
67.9K protein4004
Serum paraoxonase/arylesterase 10101
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20101
Chain A, Uracil Phosphoribosyltransferase0101
interleukin 82002
endonuclease IV1001
glp-1 receptor, partial2002
Skn7p0001
thioredoxin reductase2002
pregnane X receptor2002
hypoxia-inducible factor 1 alpha subunit4004
ATAD5 protein, partial1001
Microtubule-associated protein tau1001
Thrombopoietin1001
aldehyde dehydrogenase 1 family, member A14004
nonstructural protein 12002
arylsulfatase A2002
IDH12002
euchromatic histone-lysine N-methyltransferase 25005
v-jun sarcoma virus 17 oncogene homolog (avian)4004
peripheral myelin protein 22 isoform 11001
hemoglobin subunit beta1001
chromobox protein homolog 11001
nuclear factor erythroid 2-related factor 2 isoform 25005
huntingtin isoform 21001
flap endonuclease 12002
serine/threonine-protein kinase mTOR isoform 11001
Vpr1001
survival motor neuron protein isoform d2002
muscleblind-like protein 1 isoform 12002
lamin isoform A-delta103003
Solute carrier family 22 member 80001
Epidermal growth factor receptor0112
Amyloid-beta precursor protein1001
Thymidylate synthase0101
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
ATP-dependent phosphofructokinase2002
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
importin subunit beta-1 isoform 11001
snurportin-11001
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
Guanine nucleotide-binding protein G1001
Serine racemase0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
G1001
bromodomain adjacent to zinc finger domain 2B1001
Nuclear receptor subfamily 1 group I member 20033
HLA class I histocompatibility antigen, B alpha chain 1001
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Androgen receptor0303
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Inositol hexakisphosphate kinase 11001
Nuclear receptor subfamily 1 group I member 20011
cytochrome P450 2C9, partial1001
Gamma-aminobutyric acid receptor subunit pi1102
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10304
Gamma-aminobutyric acid receptor subunit beta-11102
Translocator protein0101
UDP-glucuronosyltransferase 2B70102
Gamma-aminobutyric acid receptor subunit delta1102
Gamma-aminobutyric acid receptor subunit gamma-21102
UDP-glucuronosyltransferase 1-60101
Gamma-aminobutyric acid receptor subunit alpha-51102
Gamma-aminobutyric acid receptor subunit alpha-31102
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0102
UDP-glucuronosyltransferase 1A40102
Gamma-aminobutyric acid receptor subunit gamma-11102
Gamma-aminobutyric acid receptor subunit alpha-21102
Gamma-aminobutyric acid receptor subunit alpha-41102
Gamma-aminobutyric acid receptor subunit gamma-31102
Gamma-aminobutyric acid receptor subunit alpha-61102
UDP-glucuronosyltransferase 2B10 0101
Gamma-aminobutyric acid receptor subunit alpha-11102
Gamma-aminobutyric acid receptor subunit beta-31102
Gamma-aminobutyric acid receptor subunit beta-21102
GABA theta subunit1102
Gamma-aminobutyric acid receptor subunit epsilon1102
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
aryl hydrocarbon receptor2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
cytochrome P450 3A4 isoform 11001
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20213
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0011
Alpha-synuclein2002
TAR DNA-binding protein 431001
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Sialidase-40202
Sialidase-10202
Sialidase-30202
Sialidase-20202
Neuraminidase 0202
Neuraminidase 0202
Neuraminidase 0202
Neuraminidase0202
Neuraminidase0101
Neuraminidase0202
Sialidase0101
Acyl-CoA desaturase 10101
Liver carboxylesterase 10001
Neuraminidase 0202
Neuraminidase 0202
Neuraminidase0101
Neuraminidase0101
Histidine decarboxylase0011
Delta-type opioid receptor0101
Delta-type opioid receptor0112
Mu-type opioid receptor0213
Kappa-type opioid receptor0112
Mu-type opioid receptor0112
Delta-type opioid receptor0101
Kappa-type opioid receptor0101
Mu-type opioid receptor0101
Mu-type opioid receptor0101
ClpP1001
GALC protein1001
Bloom syndrome protein isoform 11001
Transforming growth factor beta-1 proprotein0101
Mitogen-activated protein kinase 140112
Mothers against decapentaplegic homolog 3 0101
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
thioredoxin glutathione reductase1001
nuclear receptor ROR-gamma isoform 13003
Nuclear receptor ROR-gamma1001
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
Glutamate receptor ionotropic, NMDA 1 0101
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
USP1 protein, partial2002
Smad31001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Cytochrome P450 2C190101
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0213
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Solute carrier organic anion transporter family member 1B10202
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Chain A, Ferritin light chain1001
Cytochrome P450 3A50101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]