Compounds > para red
Page last updated: 2024-12-06

para red

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Para red, also known as 1-amino-2-naphthol, is a bright red azo dye that was historically used for coloring textiles and paints. Its synthesis involves the diazotization of aniline followed by coupling with 2-naphthol. Para red has been studied due to its potential toxicity and environmental impact, as it can be persistent in the environment. Additionally, its use in some cosmetics has raised concerns due to its potential allergic reactions in sensitive individuals. Its importance lies in its historical use as a colorant, although its application has been largely replaced by newer, safer alternatives.'

para red: a dye; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID22917
CHEMBL ID1967257
SCHEMBL ID18769
SCHEMBL ID2863152
MeSH IDM0550946

Synonyms (110)

Synonym
NCI60_001772
NCI60_038346
nsc 210792
nsc 70812
einecs 229-093-8
brn 0680469
1-((4-nitrobenzene)azo)-2-naphthol
1-((4-nitrophenyl)azo)-2-naphthol
1-((p-nitrophenyl)azo)-2-naphthol
1-(p-nitrophenylazo)-2-naphthol
2-naphthalenol, 1-((4-nitrophenyl)azo)-
2-naphthol, 1-((4-nitrophenyl)azo)-
para toner b
para red toner rpt-52
lake brown bra
carnelio para red bs
nsc70812
para red light 10333
kromon para red bs
para red
c.i. 12070
isol para red b
para red dark
monolite fast red b
carnelio para red ys
no. 7 conc. deep red
para toner y-20-1150
para toner light a-4329
para toner
1-[(4-nitrophenyl)azo]-2-naphthol
para toner red
label red
nsc-70812
lutetia red n
para toner deep a-1757
siloton red g
sanyo signal red pure
duplex para red xd 20-2900
2-naphthalenol, 1-[(4-nitrophenyl)azo]-
recolite para red g
para red ys
para toner d
para toner dark 5065
para red dark ra-1280
para red toner
lake red 2r
dainichi para red toner
conc. para red ys
para red bs
c.p. para toner light rp-2
lacal red gn
para red light
eljon para red
lake red pn
para nitraniline red
tolyl red ll
conc. para red
1-[(p-nitrophenyl)azo]-2-naphthol
tolyl red d
para red light ra-1210
para red b 20-2080
kromon para red ys
siloton red b
symuler fast para red
lutetia red b
monolite fast red ba
c.p. britelite toner rp-9
6410-10-2
federal red
recolite para red b
tolyl red m
para toner light rt-370
p-nitraniline red
nsc-210792
nsc210792
para red, dye content 95 %
P0586
1-(4-nitrophenylazo)-2-naphthol
AKOS003581970
1-[(4-nitrophenyl)diazenyl]naphthalen-2-ol
d54q24k2ei ,
unii-d54q24k2ei
2-naphthalenol, 1-(2-(4-nitrophenyl)diazenyl)-
FT-0673515
pararot
FT-0636140
ci 12070
1-(2-hydroxynaphthyl)-4'-nitroazobenzene
SCHEMBL18769
SCHEMBL2863152
DTXSID1052325
1-((4-nitrophenyl)diazenyl)naphthalen-2-ol
1-[(4-nitrophenyl)diazenyl]-2-naphthol #
c. p. britelite toner rp-9
2-naphthalenol, 1-[2-(4-nitrophenyl)diazenyl]-
c.p.para toner light rp-2
WOTPFVNWMLFMFW-ISLYRVAYSA-N
2-naphthol, 1-(p-nitrophenylazo)-
CHEMBL1967257
mfcd00003908
pararot, analytical standard
AKOS030228107
99366-04-8
para red 100 microg/ml in acetonitrile
Q906600
(e)-1-((4-nitrophenyl)diazenyl)naphthalen-2-ol
D83346
BS-50927
CS-0013963
(z)-1-(2-(4-nitrophenyl)hydrazineylidene)naphthalen-2(1h)-one

Research Excerpts

Overview

Para red is a synthetic dye and a potential genotoxic carcinogen.

ExcerptReferenceRelevance
"Para red is a synthetic dye and a potential genotoxic carcinogen. "( A sensitive and selective enzyme-linked immunosorbent assay for the analysis of Para red in foods.
Li, H; Li, J; Li, QX; Wang, J; Wei, K; Xu, T, 2012)		2.05

Effects

ExcerptReferenceRelevance
"Para Red (PR) has been isolated from food additives, and shown to be toxic to humans. "( Fluorescence resonance energy transfer for investigation of the interaction of Para Red with serum albumins.
Zeng, X; Zhang, F; Zhu, L, 2016)		2.1

Dosage Studied

ExcerptRelevanceReference
" Sudan-1 induced a non-linear dose-response curve for gene mutation and chromosomal damage in AHH-1 cells."( Metabolic influences for mutation induction curves after exposure to Sudan-1 and para red.
Johnson, GE; Parry, EM; Parry, JM; Quick, EL, 2010)		0.59
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 38.77

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index38.77 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index5.21 (4.65)
Search Engine Demand Index61.96 (26.88)
Search Engine Supply Index2.59 (0.95)

This Compound (38.77)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2-naphthol
2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.		3.3560naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
methyl red
methyl red: RN given refers to parent cpd; structure. methyl red : An azo dye consisting of benzoic acid substituted at position 2 by a 4-[(dimethylamino)phenyl]diazenyl group.		2.110
1-phenylazo-2-naphthol
1-phenylazo-2-naphthol: RN given refers to cpd without isomeric designation		2.7830
1-amino-2-naphthol
[no description available]		2.0710
orange g
orange G : An organic sodium salt that is the disodium salt of 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid. It is often combined with other yellow dyes in alcoholic solution to stain erythrocytes in trichrome methods, and is used for demonstrating cells in the pancreas and pituitary.		2.110
sudan red
[no description available]		2.4920
fat red 7b
fat red 7B: lipophilic dye		2.110
scarlet red
Scarlet Red: structure. Sudan IV : A bis(azo) compound that is 2-naphthol substituted at position 1 by a {2-methyl-4-[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound lipids in paraffin sections.		2.110azobenzenes;
bis(azo) compound;
naphthols		carcinogenic agent;
fluorochrome;
histological dye
sudan iii
sudan III: structure in first source. Sudan III : A bis(azo) compound that is 2-naphthol substituted at position 1 by a 4-{[(2-methylphenyl)diazenyl]phenyl}diazenyl group. A fat-soluble dye predominantly used for demonstrating triglycerides in frozen sections, but which may also stain some protein bound lipids in paraffin sections.		2.0710azobenzenes;
bis(azo) compound;
naphthols		carcinogenic agent;
fluorochrome;
histological dye
direct black 3
[no description available]		2.2110
ConditionIndicatedRelationship StrengthStudiesTrials
Chromosomal Breakage
[description not available]		02.0510