Page last updated: 2024-09-27

Alternariosis

Opportunistic fungal infection by a member of ALTERNARIA genus.

Synonyms(4)

Synonym
Alternariosis
Subcutaneous Alternariosis
Cutaneous Alternariosis
Dermal Alternariosis

Research Excerpts

Context

ExcerptReference
"Alternariosis has been previously shown to possess morphologic characteristics that can simulate other fungal infections."( Osmond, GW; Puri, PK; Walters, RW, 2011)

Research

Studies (40)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's32 (80.00)28.8240
2020's8 (20.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
carbamates0low10
methanol0low10
nickel0low10
econazole0low10
fluconazole0low30
flurbiprofen0low10
indomethacin0low10
ketoconazole0low10
prednisolone0low20
prednisolone acetate0low10
prednisone0low10
mannitol0low10
fusarium0low30
potassium hydroxide0low10
zinc oxide0low10
carboxin0low10
carbendazim0low10
enilconazole0low10
propiconazole0low10
itraconazole0low30
triazoles0low60
voriconazole0low80
cobalt0low10
levofloxacin0low10
epiglucan0low10
mometasone furoate0low10
posaconazole0low20
l 743,8720low10
terbinafine0low20
nabam0low10
zineb0low10
maneb0low10
amphotericin b0low60
cicaprost0low10
cyclosporine0low10
acyclovir0low10
cyclic gmp0low10
bis(3',5')-cyclic diguanylic acid0low10

Protein Targets (502)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Ferritin light chain3003
Thymidine kinase 0101
thioredoxin reductase4004
phosphopantetheinyl transferase3003
GLS protein2002
TDP1 protein130013
Smad31001
thyroid stimulating hormone receptor4004
EWS/FLI fusion protein8008
arylsulfatase A2002
euchromatic histone-lysine N-methyltransferase 27007
activating transcription factor 66006
Histone H2A.x3003
Bloom syndrome protein isoform 13003
hemoglobin subunit beta1001
atrial natriuretic peptide receptor 1 precursor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
lamin isoform A-delta109009
Solute carrier family 22 member 1 0102
ATP-binding cassette sub-family C member 30909
Multidrug resistance-associated protein 409010
Solute carrier family 22 member 60102
Bile salt export pump0303
Bile salt export pump011011
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0718
Cytochrome P450 2J20202
Disintegrin and metalloproteinase domain-containing protein 171001
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60203
Thymidine kinase 0101
Solute carrier family 22 member 80102
Canalicular multispecific organic anion transporter 10909
Thymidine kinase0101
Chain A, Beta-lactamase4004
bromodomain adjacent to zinc finger domain 2B3003
geminin110011
Gamma-aminobutyric acid receptor subunit rho-10123
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10101
Glutamate receptor 40101
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Chain A, Cruzipain2002
interleukin 83003
glucocorticoid receptor [Homo sapiens]170017
farnesoid X nuclear receptor110011
peroxisome proliferator-activated receptor delta9009
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA5005
nuclear factor erythroid 2-related factor 2 isoform 1150015
peripheral myelin protein 225005
Cytochrome P450 1A20202
Cytochrome P450 3A40809
Cytochrome P450 2D60303
Cytochrome P450 2C190303
Nuclear receptor ROR-gamma3003
Potassium voltage-gated channel subfamily H member 20606
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Stimulator of interferon genes protein0011
Stimulator of interferon genes protein0022
RocR0101
Luciferase5005
pregnane X receptor5005
GLI family zinc finger 3140014
AR protein150015
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 39009
retinoic acid nuclear receptor alpha variant 1130013
estrogen-related nuclear receptor alpha150015
pregnane X nuclear receptor140014
estrogen nuclear receptor alpha170017
67.9K protein3003
peroxisome proliferator activated receptor gamma7007
caspase-34004
IDH15005
aryl hydrocarbon receptor7007
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
v-jun sarcoma virus 17 oncogene homolog (avian)5005
thyroid hormone receptor beta isoform a5005
thyroid hormone receptor beta isoform 2110011
histone deacetylase 9 isoform 33003
Cellular tumor antigen p53130013
Methionine aminopeptidase0101
Fatty-acid amide hydrolase 10202
ATPase family AAA domain-containing protein 56006
Ataxin-26006
RAR-related orphan receptor gamma110011
progesterone receptor110011
chromobox protein homolog 16006
nuclear factor erythroid 2-related factor 2 isoform 25005
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
mitogen-activated protein kinase 12002
Voltage-dependent calcium channel gamma-2 subunit7007
Rap guanine nucleotide exchange factor 32002
Glutamate receptor 27007
Phosphodiesterase 0101
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Fumarate hydratase4004
USP1 protein, partial5005
PPM1D protein3003
polyprotein4004
Acetylcholinesterase0101
5-hydroxytryptamine receptor 40202
Transient receptor potential cation channel subfamily M member 20101
Epidermal growth factor receptor0202
Chymotrypsinogen A0303
Beta-lactamase0303
Interferon beta110011
Receptor tyrosine-protein kinase erbB-20101
Steroid 17-alpha-hydroxylase/17,20 lyase0505
Tyrosine-protein kinase Fyn0101
Heme oxygenase 1 0202
Aldo-keto reductase family 1 member B10606
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M40202
Beta-1 adrenergic receptor0202
Alpha-2A adrenergic receptor0606
Adenosine receptor A30202
Muscarinic acetylcholine receptor M10202
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Matrix metalloproteinase-90101
Indoleamine 2,3-dioxygenase 10303
Androgen receptor0303
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0404
5-hydroxytryptamine receptor 1A0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0404
Cannabinoid receptor 10202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Acetylcholinesterase0101
Heme oxygenase 20202
Sodium-dependent noradrenaline transporter 0606
Thromboxane-A synthase 0303
Histamine H2 receptor0404
Alpha-1D adrenergic receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0202
Indoleamine 2,3-dioxygenase 10202
Adenosine receptor A2a0202
Nitric oxide synthase, brain 0202
Adenosine receptor A10202
Sodium-dependent serotonin transporter0404
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Malate dehydrogenase, cytoplasmic0303
Delta-type opioid receptor0404
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0202
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0202
Neuropeptide Y receptor type 20202
5-hydroxytryptamine receptor 60202
Cholinesterase0101
Cytochrome P450 1440044
Steroid C26-monooxygenase0044
Cytochrome P450 1300011
Cytochrome P450 1300011
Steroid C26-monooxygenase0044
Mycocyclosin synthase0022
Lanosterol 14-alpha demethylase0022
Sodium-dependent dopamine transporter 0404
Lanosterol 14-alpha demethylase0426
Indoleamine 2,3-dioxygenase 20101
Calcium release-activated calcium channel protein 10101
Sigma non-opioid intracellular receptor 10404
acetylcholinesterase3003
glp-1 receptor, partial5005
hypoxia-inducible factor 1 alpha subunit6006
SMAD family member 26006
SMAD family member 36006
retinoid X nuclear receptor alpha120012
thyroid stimulating hormone receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
heat shock protein beta-15005
Alpha-synuclein1001
TAR DNA-binding protein 437007
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, BCL-2-RELATED PROTEIN A10011
apical membrane antigen 1, AMA11001
cytochrome P450 family 3 subfamily A polypeptide 49009
G7007
cytochrome P450 2D65005
unnamed protein product0101
transcriptional regulator ERG isoform 33003
heat shock protein HSP 90-alpha isoform 20002
DNA polymerase iota isoform a (long)5005
cytochrome P450 3A4 isoform 11001
bcl-2-like protein 11 isoform 10011
Gamma-aminobutyric acid receptor subunit pi1203
Histone deacetylase 30202
HLA class I histocompatibility antigen, B alpha chain 7007
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10405
Lanosterol 14-alpha demethylase0134
Aromatase0404
Gamma-aminobutyric acid receptor subunit beta-11203
Cytochrome P450 11B1, mitochondrial0303
Gamma-aminobutyric acid receptor subunit delta1203
Gamma-aminobutyric acid receptor subunit gamma-21214
Cytochrome P450 11B2, mitochondrial0303
Gamma-aminobutyric acid receptor subunit alpha-51203
Gamma-aminobutyric acid receptor subunit alpha-31203
ATP-dependent translocase ABCB10303
Gamma-aminobutyric acid receptor subunit gamma-11203
Gamma-aminobutyric acid receptor subunit alpha-21203
Gamma-aminobutyric acid receptor subunit alpha-41203
Gamma-aminobutyric acid receptor subunit gamma-31203
Gamma-aminobutyric acid receptor subunit alpha-61203
Histone deacetylase 40202
Gamma-aminobutyric acid receptor subunit alpha-11214
Gamma-aminobutyric acid receptor subunit beta-31203
Gamma-aminobutyric acid receptor subunit beta-21214
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10202
Sterol 14-alpha demethylase0033
Sterol 14-alpha demethylase0224
Histone deacetylase 70202
GABA theta subunit1203
Inositol hexakisphosphate kinase 17007
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
14-alpha sterol demethylase 0033
Histone deacetylase 80202
Gamma-aminobutyric acid receptor subunit epsilon1203
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
cytochrome P450 2C9, partial7007
heat shock protein 90, putative0002
likely tRNA 2'-phosphotransferase0101
Acid-sensing ion channel 30101
Fatty acid-binding protein, liver0202
Albumin0213
Amyloid-beta precursor protein0101
Prostaglandin G/H synthase 10405
Fatty acid-binding protein, intestinal0101
UDP-glucuronosyltransferase 2B70001
Aldo-keto reductase family 1 member C40202
Prostaglandin G/H synthase 10202
Prostaglandin G/H synthase 20415
UDP-glucuronosyltransferase 1A30001
Aldo-keto reductase family 1 member C30303
Aldo-keto reductase family 1 member C2 0202
Acid-sensing ion channel 10101
Aldo-keto reductase family 1 member C10202
Prostaglandin G/H synthase 20203
Prostaglandin G/H synthase 1 0202
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
ATAD5 protein, partial2002
Hsf1 protein0011
regulator of G-protein signaling 41001
D(1A) dopamine receptor1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
histone acetyltransferase KAT2A isoform 12002
neuropeptide S receptor isoform A2002
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10202
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Sodium- and chloride-dependent betaine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Gamma-aminobutyric acid receptor subunit alpha-60112
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase3003
Microtubule-associated protein tau1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
glucocerebrosidase1001
Parkin1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
cytochrome P450 2D6 isoform 11001
peripheral myelin protein 22 isoform 11001
cytochrome P450 2C9 precursor1001
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 11001
nuclear receptor ROR-gamma isoform 15005
DNA polymerase kappa isoform 11001
M-phase phosphoprotein 81001
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 1 0203
Prostaglandin G/H synthase 2 0203
3',5'-cyclic-AMP phosphodiesterase 0202
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Phospholipase A2, major isoenzyme0202
Procathepsin L0101
Neuronal acetylcholine receptor subunit alpha-41102
Interleukin-80101
Androgen receptor0213
Neuronal acetylcholine receptor subunit beta-21102
Polyunsaturated fatty acid 5-lipoxygenase0203
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member B10101
Prostaglandin G/H synthase 10101
Sodium-dependent dopamine transporter0101
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10101
Caspase-10001
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Histamine H2 receptor3003
C-X-C chemokine receptor type 30101
Spike glycoprotein6006
Guanine nucleotide-binding protein G3003
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Prostaglandin G/H synthase 20202
Lactoylglutathione lyase0101
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 70001
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Multidrug and toxin extrusion protein 10202
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30404
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10404
GALC protein2002
Estrogen receptor beta0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Camphor 5-monooxygenase0001
Epoxide hydrolase 10001
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Cytochrome P450 2C80101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Translocator protein0101
Cytochrome P450 7A1 0101
Estrogen receptor0101
UDP-glucuronosyltransferase 1A1 0101
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
DNA polymerase beta1001
streptokinase A precursor0011
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
DNA gyrase subunit A0101
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
potassium voltage-gated channel subfamily H member 2 isoform d3003
lethal(3)malignant brain tumor-like protein 1 isoform I1001
isocitrate dehydrogenase 1, partial1001
nuclear receptor subfamily 1, group I, member 24004
Caspase-71001
caspase-31001
flap endonuclease 11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Glucocorticoid receptor07214
Progesterone receptor0214
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Sterol 14-alpha-demethylase0022
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
luciferase0001
Estrogen receptor0202
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10606
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
thioredoxin glutathione reductase1001
aldehyde dehydrogenase 1 family, member A11001
nonstructural protein 11001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
cystic fibrosis transmembrane conductance regulator0101
C-8 sterol isomerase0101
Squalene monooxygenase 0101
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cytochrome P450 2B60101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Cholesterol 24-hydroxylase0213
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]