Page last updated: 2024-09-27

Marburg Virus Disease

An RNA virus infection of rhesus, vervet, and squirrel monkeys transmissible to man.

Synonyms(1)

Synonym
Marburg Virus Disease

Research

Studies (39)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (2.56)23.3326
1990's2 (5.13)12.5806
2000's9 (23.08)18.1394
2010's22 (56.41)28.8240
2020's5 (12.82)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low20
coumarin0low10
formaldehyde0low10
bepridil0low10
cyproheptadine0low10
oxamniquine0low10
alanine0low20
adenosine monophosphate0low20
penicillanic acid0low10
pyrazines0low40
citrulline0low10
mannose0low10
gold0low20
ammonium chloride0low10
4-methoxyamphetamine0low10
zidovudine0low10
ticarcillin0low10
amikacin0low10
adenosine0low20
sertraline0low10
fibrinogen0low10
proline0low10
benzofurans0low10
fibrin0low10
fosfomycin0low10
favipiravir0low40
benztropine0low10
toremifene0low10
myelin basic protein0low10
bafilomycin a10low10
eritoran0low10
warfarin0low10
transforming growth factor beta0low10
ihvr-110290low10
s 89320low20
ridostin0low10
eye0low10

Protein Targets (486)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 2A0314
5-hydroxytryptamine receptor 1A0314
5-hydroxytryptamine receptor 1B0314
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0213
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0426
Sodium-dependent serotonin transporter0303
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma5005
TDP1 protein8008
AR protein7007
nuclear receptor subfamily 1, group I, member 35005
cytochrome P450 family 3 subfamily A polypeptide 44004
glucocorticoid receptor [Homo sapiens]6006
estrogen-related nuclear receptor alpha8008
pregnane X nuclear receptor6006
estrogen nuclear receptor alpha9009
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
nuclear factor erythroid 2-related factor 2 isoform 23003
heat shock protein beta-12002
importin subunit beta-1 isoform 11001
snurportin-11001
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
lamin isoform A-delta107007
Voltage-dependent calcium channel gamma-2 subunit5005
Bile salt export pump0909
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Glutamate receptor 25005
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 431001
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 52002
Ataxin-25005
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 45005
retinoid X nuclear receptor alpha4004
NPYLR7B0011
arylsulfatase A3003
IDH14004
Histone H2A.x3003
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 11001
flap endonuclease 11001
nuclear receptor ROR-gamma isoform 11001
peripheral myelin protein 228008
survival motor neuron protein isoform d3003
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70022
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 33003
Purine nucleoside phosphorylase0202
Epidermal growth factor receptor0101
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0303
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30427
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0003
Adenosine receptor A10112
Adenosine receptor A30101
Adenosine receptor A2a0225
Adenosine receptor A2b0012
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0203
Adenosine receptor A10337
Adenosine receptor A2a0112
Adenylate kinase isoenzyme 1 0203
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
euchromatic histone-lysine N-methyltransferase 25005
v-jun sarcoma virus 17 oncogene homolog (avian)3003
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0001
Fructose-1,6-bisphosphatase 10101
2-dehydropantoate 2-reductase0112
Inosine-5'-monophosphate dehydrogenase0101
Cytochrome P450 2C9 0404
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0202
5'-nucleotidase0001
Choline O-acetyltransferase0101
GTP:AMP phosphotransferase AK3, mitochondrial0001
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 0325
P2Y purinoceptor 110011
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
ATP-dependent phosphofructokinase4004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Carbonic anhydrase 10103
Carbonic anhydrase 20103
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0202
Proton-coupled amino acid transporter 10202
Adenosine deaminase0001
Carbonic anhydrase 40001
histone acetyltransferase KAT2A isoform 12002
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40303
Canalicular multispecific organic anion transporter 10303
Aminoglycoside 3'-phosphotransferase 0001
P2X purinoceptor 30101
V-type proton ATPase subunit S10101
Vacuolar proton pump subunit B 0101
Spike glycoprotein0044
Replicase polyprotein 1ab0044
potassium voltage-gated channel subfamily H member 2 isoform d3003
thyroid hormone receptor beta isoform 26006
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Transmembrane protease serine 20044
5-hydroxytryptamine receptor 40606
Cellular tumor antigen p535005
Procathepsin L0044
Aldo-keto reductase family 1 member B10606
Muscarinic acetylcholine receptor M20606
Muscarinic acetylcholine receptor M40606
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor0606
Replicase polyprotein 1a0044
Replicase polyprotein 1ab0044
Replicase polyprotein 1ab0044
Replicase polyprotein 1ab0246
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10606
Alpha-2B adrenergic receptor0606
Alpha-2C adrenergic receptor0606
Muscarinic acetylcholine receptor M30404
Sodium-dependent noradrenaline transporter 0617
Sodium-dependent dopamine transporter0202
Histamine H2 receptor0404
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2A0606
5-hydroxytryptamine receptor 2C0606
Histamine H1 receptor0415
D(3) dopamine receptor0404
5-hydroxytryptamine receptor 2B0606
Histamine H2 receptor2002
5-hydroxytryptamine receptor 60505
Spike glycoprotein5049
Sodium-dependent dopamine transporter 0415
Sigma non-opioid intracellular receptor 10404
Angiotensin-converting enzyme 2 0044
acetylcholinesterase1001
hypoxia-inducible factor 1 alpha subunit1001
SMAD family member 22002
ATAD5 protein, partial3003
Fumarate hydratase3003
GLS protein2002
PPM1D protein5005
SMAD family member 32002
GLI family zinc finger 34004
Microtubule-associated protein tau1001
caspase 7, apoptosis-related cysteine protease2002
aldehyde dehydrogenase 1 family, member A14004
estrogen receptor 2 (ER beta)1001
progesterone receptor2002
retinoic acid nuclear receptor alpha variant 15005
G1001
cytochrome P450 2D62002
polyprotein3003
67.9K protein3003
glucocerebrosidase1001
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
caspase-32002
activating transcription factor 61001
Caspase-72002
chromobox protein homolog 15005
caspase-32002
huntingtin isoform 22002
nuclear factor erythroid 2-related factor 2 isoform 14004
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 1001
Lethal factor0101
Cytochrome P450 2J20202
Inositol monophosphatase 11001
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Envelope glycoprotein0044
Potassium voltage-gated channel subfamily H member 20606
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0101
Inositol hexakisphosphate kinase 11001
cytochrome P450 2C9, partial1001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
General amino-acid permease GAP10001
Nitric oxide synthase, brain0101
Nitric oxide synthase, brain 0101
Chain A, Beta-lactamase4004
pregnane X receptor1001
USP1 protein, partial3003
GALC protein1001
farnesoid X nuclear receptor4004
nuclear receptor subfamily 1, group I, member 22002
thyroid hormone receptor beta isoform a2002
DNA polymerase iota isoform a (long)3003
glycogen synthase kinase-3 alpha0001
muscleblind-like protein 1 isoform 12002
Exportin-10101
Carbonic anhydrase 120102
NAD-dependent histone deacetylase SIR20103
Carbonic anhydrase 30101
Cytochrome P450 2A60001
Aldo-keto reductase family 1 member B10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60101
Cytochrome P450 2A50001
Amine oxidase [flavin-containing] A 0101
Acetylcholinesterase0101
Acetylcholinesterase0101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40102
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0101
Carbonic anhydrase 40101
Carbonic anhydrase 60101
Substance-P receptor0001
Carbonic anhydrase 5A, mitochondrial0101
UDP-glucuronosyltransferase 2B10 0101
Carbonic anhydrase 70101
Quinone oxidoreductase0001
Beta-secretase 10101
Sorbitol dehydrogenase0101
Induced myeloid leukemia cell differentiation protein Mcl-10202
Carbonic anhydrase 90102
Zn finger protein 0101
Dihydroorotate dehydrogenase 0101
Carbonic anhydrase 130101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
phosphopantetheinyl transferase3003
thyroid stimulating hormone receptor2002
EWS/FLI fusion protein2002
cytochrome P450 2D6 isoform 11001
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C19 precursor1001
D(1A) dopamine receptor2002
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 13003
muscarinic acetylcholine receptor M12002
lethal factor (plasmid)2002
chaperonin GroEL1001
Sodium-dependent noradrenaline transporter0101
Prostaglandin G/H synthase 10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Glycogen phosphorylase, brain form0101
Glycogen phosphorylase, muscle form0101
Angiotensin-converting enzyme0404
D(2) dopamine receptor0202
D0202
D(3) dopamine receptor0202
Endothelin receptor type B0101
D(1A) dopamine receptor0202
Endothelin receptor type B0101
D(1B) dopamine receptor0202
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
UDP-glucuronosyltransferase 1A30001
D(2) dopamine receptor0101
D(2) dopamine receptor0303
Sodium-dependent serotonin transporter0101
Nuclear receptor subfamily 3 group C member 3 0404
Histone-lysine N-methyltransferase SETD70202
Transporter0202
apical membrane antigen 1, AMA11001
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
geminin5005
Lysine-specific demethylase 4A0101
Guanine nucleotide-binding protein G2002
Hypoxia-inducible factor 1-alpha0011
Methylcytosine dioxygenase TET20101
Deoxyhypusine hydroxylase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Purine nucleoside phosphorylase 0101
transcriptional regulator ERG isoform 31001
DNA polymerase kappa isoform 11001
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
NS5 0112
interleukin 81001
Thrombopoietin1001
peroxisome proliferator activated receptor gamma2002
alpha-galactosidase1001
peripheral myelin protein 22 isoform 11001
cytochrome P450 3A4 isoform 11001
Gamma-aminobutyric acid receptor subunit pi1001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Nuclear receptor ROR-gamma1001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Adenosine receptor A10101
Genome polyprotein0011
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
glp-1 receptor, partial1001
Smad31001
nonstructural protein 11001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
NPC intracellular cholesterol transporter 1 precursor1001
vitamin D3 receptor isoform VDRA1001
ras-related protein Rab-9A1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
ATP-dependent translocase ABCB10101
Cytochrome P450 3A40101
Cytochrome P450 2D60101
Transcriptional activator protein LuxR0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Melanocortin receptor 50202
Cytochrome P450 2C190101
D(1A) dopamine receptor1001
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Solute carrier family 22 member 80101
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Kappa-type opioid receptor0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Albumin0022
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
pyruvate kinase PKM isoform a1001
serine/threonine-protein kinase PLK11001
tyrosine-protein kinase Yes1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Ectonucleoside triphosphate diphosphohydrolase 10001
Solute carrier family 22 member 60001
Thymidine kinase, cytosolic0203
Protein kinase C beta type0101
DNA polymerase beta0101
Thymidine kinase, cytosolic 0001
Solute carrier organic anion transporter family member 1A30001
Thymidylate kinase0101
Protein kinase C epsilon type0101
Thymidine kinase 0102
Solute carrier family 22 member 60001
Solute carrier family 22 member 70001
Reverse transcriptase/RNaseH 0126
Solute carrier family 22 member 80001
Solute carrier family 22 member 110001
Thymidine kinase0102
Solute carrier family 22 member 70001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]