Chondrosteoma

A cartilage-capped benign tumor that often appears as a stalk on the surface of bone. It is probably a developmental malformation rather than a true neoplasm and is usually found in the metaphysis of the distal femur, proximal tibia, or proximal humerus. Osteochondroma is the most common of benign bone tumors.

Synonym
Osteochondroma
Chondrosteoma
Exostosis, Cartilaginous
Exostosis, Osteocartilaginous

Excerpt	Reference
"In the hand, osteochondromas are rarely found."	( Laflamme, GY; Stanciu, C, 1998)
"Osteochondroma is observed in 1-2% of the population and may present with vascular complications."	( Buitrago-Téllez, CH; Gürke, L; Rosenthal, R; Stierli, P, 2001)
"Osteochondroma is a common benign bone tumor that sometimes causes vascular complications when the lesion is situated near the knee."	( Harimaya, K; Iwamoto, Y; Matsuda, S; Sakamoto, A; Tanaka, K, 2002)
"Spinal osteochondromas are rare and tend to appear in young adults."	( Mochida, J; Nomura, T; Sakai, D; Toh, E, 2002)
"Hereditary osteochondromas are often caused by mutation in the EXT1 gene."	( Evron, Z; Fridkin, M; Glaser, T; Kollander, Y; Nevo, Z; Posternak, N; Robinson, D; Trebicz-Geffen, M, 2003)
"The osteochondroma is a common, benign, primary tumor of bone."	( Jones, KB; Morcuende, JA, 2003)
"Osteochondroma is the most common primary benign bone tumor."	( Marco, RA; Samartzis, D, 2006)
"Osteochondroma is a rare primary benign bone tumor that can occur in the sacrum."	( Marco, RA; Samartzis, D, 2006)
"Mandibular condylar osteochondroma is thought to be a relatively rare lesion with only 90 cases documented in the English language literature to date."	( Bhatt, K; Bhutia, O; Roychoudhury, A; Roychoudhury, S; Yadav, R, 2011)
"Osteochondroma is one of the most common primary benign bone tumors."	( Ho, JW; Lee, YK, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	9 (10.59)	23.3326
1990's	12 (14.12)	12.5806
2000's	36 (42.35)	18.1394
2010's	23 (27.06)	28.8240
2020's	5 (5.88)	9.53

Drug	Relationship Strength	Studies
gamma-aminobutyric acid	low	1
busulfan	low	2
pentetic acid	low	1
etidronate	low	1
gabapentin	low	1
activins	low	1
phenylbutazone	low	1
meglumine	low	1
limestone	low	1
hematoxylin	low	1
eosine yellowish-(ys)	low	1
technetium	low	1
thorium	low	1
gadolinium	low	3
tricalcium phosphate	low	2
calcium pyrophosphate	low	1
thallium chloride	low	1
trolamine salicylate	low	3
propiconazole	low	3
fomesafen	low	1
fluorodeoxyglucose f18	low	3
4-nitrophenyl beta-d-xyloside	low	1
technetium tc 99m hydroxymethylene diphosphonate	low	1
6-bromoindirubin-3'-oxime	low	1
melphalan	low	1
glycosides	low	1
isomethyleugenol	low	1
stilbenes	low	1
safranine t	low	1
succimer	low	1
tamoxifen	low	2
isotretinoin	low	1
thallium	low	1
radium	low	1
thorium x	low	1
gadolinium dtpa	low	2
mart-1 antigen	low	1
palovarotene	low	1
losartan potassium	low	1
acid phosphatase	low	1
gadofosveset trisodium	low	1
ldn 193189	low	1
heparitin sulfate	low	8
warfarin	low	1
transforming growth factor beta	low	2
cyclin d1	low	1
technetium tc 99m medronate	low	4
chondroitin sulfates	low	1
technetium tc 99m dimercaptosuccinic acid	low	1

Protein Targets (498)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	5	0	0	5
Chain A, Beta-lactamase	4	0	0	4
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Ferritin light chain	5	0	0	5
Chain A, Cruzipain	2	0	0	2
Luciferase	6	0	0	6
acid sphingomyelinase	2	0	0	2
endonuclease IV	2	0	0	2
dopamine D1 receptor	1	0	0	1
glp-1 receptor, partial	3	0	0	3
SUMO-1-specific protease	0	1	0	1
ATAD5 protein, partial	3	0	0	3
Fumarate hydratase	4	0	0	4
NFKB1 protein, partial	1	0	0	1
GLS protein	3	0	0	3
PPM1D protein	5	0	0	5
TDP1 protein	9	0	0	9
Microtubule-associated protein tau	5	0	0	5
SUMO1/sentrin specific peptidase 7	0	1	0	1
Thrombopoietin	1	0	0	1
Smad3	3	0	0	3
apical membrane antigen 1, AMA1	5	0	0	5
regulator of G-protein signaling 4	7	0	0	7
cytochrome P450 family 3 subfamily A polypeptide 4	6	0	0	6
EWS/FLI fusion protein	6	0	0	6
nonstructural protein 1	4	0	0	4
estrogen-related nuclear receptor alpha	12	0	0	12
G	4	0	0	4
cytochrome P450 2D6	2	0	0	2
polyprotein	4	0	0	4
Glycogen synthase kinase-3 beta	0	1	0	1
67.9K protein	4	0	0	4
Parkin	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
arylsulfatase A	4	0	0	4
pyruvate kinase	2	0	0	2
LacZ protein (plasmid)	0	1	0	1
IDH1	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	10	0	0	10
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
[Tau protein] kinase	0	1	0	1
Bloom syndrome protein isoform 1	6	0	0	6
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
peripheral myelin protein 22 isoform 1	3	0	0	3
cellular tumor antigen p53 isoform a	3	0	0	3
D(1A) dopamine receptor	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
chromobox protein homolog 1	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
transcriptional regulator ERG isoform 3	3	0	0	3
importin subunit beta-1 isoform 1	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
ras-related protein Rab-9A	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
matrix metalloproteinase-14 preproprotein	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
snurportin-1	2	0	0	2
melanocortin receptor 4	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	6	0	0	6
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	4	0	0	4
geminin	9	0	0	9
survival motor neuron protein isoform d	5	0	0	5
cytochrome P450 3A4 isoform 1	5	0	0	5
M-phase phosphoprotein 8	4	0	0	4
transient receptor potential cation channel subfamily V member 1	1	0	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
streptokinase A precursor	0	0	2	2
muscarinic acetylcholine receptor M1	2	0	0	2
sentrin-specific protease 8	0	1	0	1
lamin isoform A-delta10	7	0	0	7
pyruvate kinase PKM isoform b	1	0	0	1
chaperonin GroEL	1	0	0	1
neuropeptide S receptor isoform A	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	5	2	0	7
Aurora kinase A	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Cyclin-T1	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Interferon beta	7	0	0	7
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Amyloid-beta precursor protein	1	0	0	1
Integrin beta-3	3	0	0	3
Estrogen receptor	0	0	2	3
Cyclin-dependent kinase 1	0	1	0	1
Integrin alpha-IIb	3	0	0	3
Ornithine decarboxylase	1	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cyclin-dependent kinase 4	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	5	2	0	7
Gamma-aminobutyric acid receptor subunit delta	5	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	5	2	1	8
Interferon-induced, double-stranded RNA-activated protein kinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	5	2	0	7
Cyclin-A2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	5	2	0	7
G1/S-specific cyclin-D1	0	1	0	1
G1/S-specific cyclin-E1	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	5	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	5	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	5	2	0	7
Dual specificity protein kinase CLK1	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
Cyclin-dependent kinase 7	0	1	0	1
Cyclin-dependent kinase 9	0	1	0	1
Cyclin-H	0	1	0	1
CDK-activating kinase assembly factor MAT1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	5	2	1	8
Gamma-aminobutyric acid receptor subunit beta-3	5	2	0	7
Guanine nucleotide-binding protein G	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-2	5	2	1	8
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Inositol monophosphatase 1	2	0	0	2
Cyclin-dependent-like kinase 5	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
Estrogen receptor beta	0	0	2	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
GABA theta subunit	5	2	0	7
Inositol hexakisphosphate kinase 1	4	0	0	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	1	0	1
Aurora kinase B	0	1	0	1
Bile acid receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	5	2	0	7
Aurora kinase C	0	1	0	1
cytochrome P450 2C9, partial	4	0	0	4
phosphoglycerate kinase	2	0	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
ATP-dependent phosphofructokinase	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
15-lipoxygenase, partial	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
thyroid stimulating hormone receptor	4	0	0	4
glucocorticoid receptor [Homo sapiens]	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	8	0	0	8
retinoid X nuclear receptor alpha	6	0	0	6
pregnane X nuclear receptor	8	0	0	8
estrogen nuclear receptor alpha	12	0	0	12
aryl hydrocarbon receptor	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
thyroid hormone receptor beta isoform 2	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	8	0	0	8
lethal factor (plasmid)	2	0	0	2
ATP-binding cassette sub-family C member 3	0	5	0	5
Multidrug resistance-associated protein 4	0	5	0	5
Bile salt export pump	0	8	0	8
Matrix metalloproteinase-9	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	4	0	4
GLI family zinc finger 3	8	0	0	8
farnesoid X nuclear receptor	5	0	0	5
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
peripheral myelin protein 22	4	0	0	4
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Glutamate receptor 2	6	0	0	6
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
progesterone receptor	5	0	0	5
peroxisome proliferator activated receptor gamma	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
Histone H2A.x	3	0	0	3
USP1 protein, partial	6	0	0	6
thioredoxin glutathione reductase	3	0	0	3
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
thioredoxin reductase	4	0	0	4
Hsf1 protein	0	0	1	1
thyroid hormone receptor beta isoform a	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
TAR DNA-binding protein 43	4	0	0	4
Histone deacetylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Histone deacetylase 8	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	1	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	1	0	0	1
Mcl-1	0	1	0	1
phosphopantetheinyl transferase	5	0	0	5
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
hypothetical protein, conserved	1	0	0	1
glucocerebrosidase	3	0	0	3
luciferase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
vitamin D3 receptor isoform VDRA	5	0	0	5
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
intestinal alkaline phosphatase precursor	0	0	1	1
DNA polymerase beta	1	0	0	1
flap endonuclease 1	2	0	0	2
serine/threonine-protein kinase PLK1	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA polymerase kappa isoform 1	1	0	0	1
Vif	0	1	0	1
Tat	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Rap guanine nucleotide exchange factor 3	1	0	0	1
Pyruvate kinase PKM	0	1	0	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
Histamine H2 receptor	5	0	0	5
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
RAR-related orphan receptor gamma	8	0	0	8
AR protein	7	0	0	7
estrogen receptor 2 (ER beta)	5	0	0	5
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
peroxisome proliferator-activated receptor delta	5	0	0	5
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	5	0	0	5
thyroid stimulating hormone receptor	2	0	0	2
activating transcription factor 6	3	0	0	3
Caspase-7	3	0	0	3
caspase-3	3	0	0	3
heat shock protein beta-1	2	0	0	2
Ornithine decarboxylase	0	0	0	1
Cellular tumor antigen p53	7	0	0	7
Adenosine receptor A3	0	4	0	4
Retinoic acid receptor alpha	0	1	0	1
Alpha-1B adrenergic receptor	0	4	0	4
Alpha-2B adrenergic receptor	0	4	0	4
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	4	0	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Olfactory receptor 51E2	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Bone morphogenetic protein 4	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Bone morphogenetic protein receptor type-1A	0	1	0	1
Activin receptor type-1B	0	1	0	1
TGF-beta receptor type-1	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	1	0	1
Activin receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	1	0	1
Dual specificity protein kinase CLK2	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	1	0	1
Activin receptor type-1	0	1	0	1
Bone morphogenetic protein receptor type-2	0	1	0	1
5'-AMP-activated protein kinase subunit beta-1	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
caspase-3	2	0	0	2
Nuclear receptor ROR-gamma	1	0	0	1
Spike glycoprotein	2	0	1	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
ATPase family AAA domain-containing protein 5	4	0	0	4
Ataxin-2	4	0	0	4
GALC protein	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
pregnane X receptor	2	0	0	2
Estrogen receptor 1	0	1	0	1
cytochrome P450 2C9 precursor	1	0	0	1
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cytochrome P450 2C9	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
Cytochrome P450 3A4	0	2	0	2
heat shock protein 90, putative	0	0	0	1
Glucocorticoid receptor	0	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Chain A, CES1 protein	0	1	0	1
acetylcholinesterase	1	0	0	1
DNA polymerase III, partial	1	0	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	1	0	0	1
Spike glycoprotein	0	0	1	1
cytochrome P450 2D6 isoform 1	1	0	0	1
interferon gamma precursor	0	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
5-hydroxytryptamine receptor 4	0	2	0	2
Serine/threonine-protein kinase D3	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Estrogen receptor	0	2	1	4
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Progesterone receptor	0	1	0	1
Procathepsin L	0	0	1	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
ATP-dependent translocase ABCB1	0	2	1	3
Beta-1 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Androgen receptor	0	2	0	2
Protein kinase C alpha type	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	0	1
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Substance-P receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Adenosine receptor A1	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Alpha-synuclein	1	0	0	1
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Protein kinase C iota type	0	1	0	1
Melanocortin receptor 3	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Protein kinase C epsilon type	0	1	0	1
Protein kinase C theta type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Estrogen receptor beta	0	2	1	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
Albumin	0	0	1	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research Excerpts

Overview

Research

Studies (85)

Protein Targets (498)

Chondrosteoma

Synonyms(4)

Research Excerpts

Overview

Research

Studies (85)

Drugs Studied (56)

Protein Targets (498)