Page last updated: 2024-09-27

Chloracne

ACNE-like skin eruptions caused by exposure to CHLORINE-containing compounds. Exposure can be by inhalation, ingestion, or through the skin. Chloracne is often seen in people who have occupational contact with chlorinated pesticides, wood preservatives, and sealants.

Synonyms(2)

Synonym
Chlorine Acne
Chloracne

Research Excerpts

Overview

ExcerptReference
"Chloracne is an acneiform eruption caused though poisoning by aromatic compounds (usually halogenated) showing a specific molecular configuration."( Bojar, RA; Gawkrodger, DJ; Harris, G, 2009)
"Chloracne is characterized by the onset of numerous comedo-like lesions and yellowish cysts on the face, particularly on the cheeks, that can spread to the trunk and other body regions not usually affected by acne vulgaris, with diffuse grayish skin pigmentation and sometimes associated with hypertrichosis and areas of folliculitis."( Infusino, SD; Kasapi, E; Passarini, B, 2010)

Treatment

ExcerptReference
"We describe chloracne-like eruptions in two different patients with no exposure to aromatic hydrocarbons but who were recently started on sorafenib for treatment of metastatic renal carcinoma."( Hughes, M; Pickert, A; Wells, M, 2011)

Research

Studies (22)

TimeframeStudies, This Condition (%)All Conditions %
pre-19908 (36.36)23.3326
1990's0 (0.00)12.5806
2000's4 (18.18)18.1394
2010's9 (40.91)28.8240
2020's1 (4.55)9.53
DrugIndicatedRelationship StrengthStudiesTrials
benzene0low10
chlorine0low20
dibenzofuran0low10
kynurenine0low10
niacinamide0low10
beta-naphthoflavone0low10
ddt0low10
kynurenic acid0low10
2,3,4,6-tetrachlorophenol0low10
tryptophan0low10
phencyclidine0low10
quinoxalines0low10
diphenyl0low10
thiazoles0low10
hypochlorous acid0low10
chlorine0low40
3,4,3',4'-tetrachloroazobenzene0low10
agent orange0low10
triazoles0low10
gefitinib0low10
erlotinib hydrochloride0low10
sorafenib0low10
benzofurans0low20
phenylephrine hydrochloride0low10
involucrin0low10
plx40320low10
epidermal growth factor0low10
transforming growth factor alpha0low10

Protein Targets (829)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Luciferase3003
interleukin 82002
RAR-related orphan receptor gamma5005
GLI family zinc finger 39009
AR protein6006
thyroid stimulating hormone receptor4004
estrogen receptor 2 (ER beta)3003
nuclear receptor subfamily 1, group I, member 35005
progesterone receptor5005
glucocorticoid receptor [Homo sapiens]5005
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha6006
estrogen-related nuclear receptor alpha9009
farnesoid X nuclear receptor4004
pregnane X nuclear receptor4004
estrogen nuclear receptor alpha9009
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma4004
aryl hydrocarbon receptor6006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
Histone H2A.x3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
thyroid hormone receptor beta isoform 25005
heat shock protein beta-14004
mitogen-activated protein kinase 13003
nuclear factor erythroid 2-related factor 2 isoform 17007
Voltage-dependent calcium channel gamma-2 subunit5005
Cellular tumor antigen p536006
Glutamate receptor 25107
Nuclear receptor ROR-gamma2002
Peroxisome proliferator-activated receptor alpha1001
ATPase family AAA domain-containing protein 53003
Ataxin-23003
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
pregnane X receptor2002
cellular tumor antigen p53 isoform a2002
Endolysin0011
Integrin beta-31001
Integrin alpha-IIb1001
Nrf21001
PAX80001
glp-1 receptor, partial2002
SMAD family member 22002
SMAD family member 32002
TDP1 protein7007
caspase 7, apoptosis-related cysteine protease2002
hypothetical protein, conserved1001
67.9K protein3003
caspase-32002
LMP1 [Human herpesvirus 4]0001
thyroid stimulating hormone receptor4004
activating transcription factor 63003
v-jun sarcoma virus 17 oncogene homolog (avian)3003
histone deacetylase 9 isoform 31001
Protein skinhead-10101
Gamma-aminobutyric acid receptor subunit pi0101
Cytochrome P450 1A10101
Cytochrome P450 1A20303
Tyrosine-protein kinase Fyn0134
Cytochrome P450 2A60101
Gamma-aminobutyric acid receptor subunit beta-10101
NAD0001
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Cytochrome P450 2B60202
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit alpha-20101
Mitogen-activated protein kinase 3 0235
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-60101
Aryl hydrocarbon receptor0034
Quinone oxidoreductase0001
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Guanine nucleotide-binding protein G1001
Gamma-aminobutyric acid receptor subunit beta-20101
Xanthine dehydrogenase/oxidase0101
NAD(P)H dehydrogenase [quinone] 10001
GABA theta subunit0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Histamine H3 receptor0101
Broad substrate specificity ATP-binding cassette transporter ABCG20314
Carbonic anhydrase 10203
Carbonic anhydrase 20203
Carbonic anhydrase 40102
Carbonic anhydrase0102
Carbonic anhydrase 150102
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, Cruzipain1001
hypoxia-inducible factor 1 alpha subunit1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
cytochrome P450 family 3 subfamily A polypeptide 41001
G1001
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
euchromatic histone-lysine N-methyltransferase 24004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
Caspase-73003
thyroid hormone receptor beta isoform a2002
potassium voltage-gated channel subfamily H member 2 isoform d3003
caspase-33003
nuclear factor NF-kappa-B p105 subunit isoform 11001
geminin6006
peripheral myelin protein 224004
lethal factor (plasmid)2002
lamin isoform A-delta104004
Interferon beta2002
HLA class I histocompatibility antigen, B alpha chain 1001
Androgen receptor0101
Inositol hexakisphosphate kinase 11001
cytochrome P450 2C9, partial1001
Cytochrome P450 1A10011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
aldehyde dehydrogenase 1 family, member A12002
Transthyretin0001
Epidermal growth factor receptor0549
Receptor tyrosine-protein kinase erbB-20325
Serine/threonine-protein kinase B-raf 0303
Leukotriene C4 synthase0022
acetylcholinesterase1001
Fumarate hydratase2002
Microtubule-associated protein tau3003
EWS/FLI fusion protein3003
cytochrome P450 2D61001
polyprotein2002
vitamin D3 receptor isoform VDRA1001
epidermal growth factor receptor isoform a precursor1102
tyrosine-protein kinase Yes3003
Bone morphogenetic protein receptor type-1B0033
Cell division cycle 7-related protein kinase0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0224
Serine/threonine-protein kinase PLK40134
Serine/threonine-protein kinase 250022
ATP-dependent RNA helicase DDX3X0033
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0022
Pyridoxal kinase0033
Citron Rho-interacting kinase0033
Serine/threonine-protein kinase RIO30022
Dual specificity mitogen-activated protein kinase kinase 70022
Serine/threonine-protein kinase Chk10033
Inhibitor of nuclear factor kappa-B kinase subunit beta0022
Peripheral plasma membrane protein CASK0022
Aurora kinase A0134
Cyclin-G-associated kinase0134
Serine/threonine-protein kinase DCLK10022
Inhibitor of nuclear factor kappa-B kinase subunit alpha0022
Muscle, skeletal receptor tyrosine-protein kinase0022
Ephrin type-B receptor 60033
Peroxisomal acyl-coenzyme A oxidase 30033
Mitogen-activated protein kinase 130123
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
ATP-binding cassette sub-family C member 30101
Multidrug resistance-associated protein 40101
3-phosphoinositide-dependent protein kinase 10022
Mitogen-activated protein kinase kinase kinase 130022
Death-associated protein kinase 30022
Mitogen-activated protein kinase kinase kinase 70022
Receptor-interacting serine/threonine-protein kinase 20134
Mitotic checkpoint serine/threonine-protein kinase BUB10033
NUAK family SNF1-like kinase 10022
Dynamin-like 120 kDa protein, mitochondrial0033
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0022
Tyrosine-protein kinase JAK20033
Rho-associated protein kinase 20033
Serine/threonine-protein kinase ULK10033
Serine/threonine-protein kinase/endoribonuclease IRE10033
Ribosomal protein S6 kinase alpha-50033
U5 small nuclear ribonucleoprotein 200 kDa helicase0033
Ribosomal protein S6 kinase alpha-40033
Serine/threonine-protein kinase 160033
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0022
Serine/threonine-protein kinase PAK 30022
Cyclin-dependent kinase-like 50022
Serine/threonine-protein kinase 17B0022
Serine/threonine-protein kinase 100033
Serine/threonine-protein kinase D30033
Cyclin-dependent kinase 140022
Bile salt export pump0202
Structural maintenance of chromosomes protein 20033
Mitogen-activated protein kinase kinase kinase 60033
Serine/threonine-protein kinase OSR10022
Mitogen-activated protein kinase kinase kinase kinase 40033
Serine/threonine-protein kinase LATS10033
Serine/threonine-protein kinase PAK 40033
Serine/threonine-protein kinase Chk20022
Tyrosine-protein kinase ABL10336
RAF proto-oncogene serine/threonine-protein kinase0337
High affinity nerve growth factor receptor0033
Guanine nucleotide-binding protein G(i) subunit alpha-20022
ADP/ATP translocase 20033
Cytochrome P450 2E10101
Protein kinase C beta type0033
Insulin receptor0235
Tyrosine-protein kinase Lck0134
Cyclin-dependent kinase 10033
Glycogen phosphorylase, liver form0033
Tyrosine-protein kinase Fes/Fps0033
Macrophage colony-stimulating factor 1 receptor0123
Adenine phosphoribosyltransferase0033
Tyrosine-protein kinase Yes0033
Tyrosine-protein kinase Lyn0033
Proto-oncogene tyrosine-protein kinase receptor Ret0336
Insulin-like growth factor 1 receptor0033
ATP-dependent translocase ABCB10112
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0033
Hepatocyte growth factor receptor0134
Tyrosine-protein kinase HCK0235
Proto-oncogene tyrosine-protein kinase ROS0022
Platelet-derived growth factor receptor beta0134
Tyrosine-protein kinase Fgr0033
Quinolone resistance protein NorA0101
Wee1-like protein kinase 20022
Uncharacterized serine/threonine-protein kinase SBK30022
Serine/threonine-protein kinase A-Raf0235
Cytochrome P450 2C80101
Mast/stem cell growth factor receptor Kit0123
Glycogen phosphorylase, brain form0033
Breakpoint cluster region protein0134
Serine/threonine-protein kinase pim-10033
Fibroblast growth factor receptor 10134
DNA topoisomerase 2-alpha0033
Myosin light chain kinase, smooth muscle0022
Cyclin-dependent kinase 40134
ADP/ATP translocase 30033
Inosine-5'-monophosphate dehydrogenase 20033
Proto-oncogene tyrosine-protein kinase Src0235
cAMP-dependent protein kinase type II-alpha regulatory subunit0033
Insulin receptor-related protein0022
Serine/threonine-protein kinase B-raf05511
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0033
Ribosyldihydronicotinamide dehydrogenase [quinone]0033
Platelet-derived growth factor receptor alpha0123
Tyrosine-protein kinase Fer0033
Protein kinase C alpha type0033
cAMP-dependent protein kinase catalytic subunit alpha0033
Vascular endothelial growth factor receptor 1 0123
General transcription and DNA repair factor IIH helicase subunit XPD0033
Interferon-induced, double-stranded RNA-activated protein kinase0022
Casein kinase II subunit alpha'0033
Ras-related protein Rab-6A0033
Serine/threonine-protein kinase MAK0022
Cyclin-dependent kinase 11B0022
Ephrin type-A receptor 10033
Fibroblast growth factor receptor 20022
Receptor tyrosine-protein kinase erbB-30123
Multifunctional protein ADE20033
Fibroblast growth factor receptor 40022
Fibroblast growth factor receptor 30022
cAMP-dependent protein kinase catalytic subunit gamma0022
cAMP-dependent protein kinase catalytic subunit beta0033
Ferrochelatase, mitochondrial0044
Ribosomal protein S6 kinase beta-10033
Tyrosine-protein kinase JAK10033
Sodium-dependent dopamine transporter0101
Protein kinase C eta type0022
Cyclin-dependent kinase 20134
Beta-adrenergic receptor kinase 10033
Cruzipain0101
Probable ATP-dependent RNA helicase DDX60033
Activin receptor type-2A0022
MAP/microtubule affinity-regulating kinase 30033
Deoxycytidine kinase0033
Mitogen-activated protein kinase 10134
Ephrin type-A receptor 20033
Ephrin type-A receptor 30022
Ephrin type-A receptor 80022
Ephrin type-B receptor 20033
Leukocyte tyrosine kinase receptor0022
Non-receptor tyrosine-protein kinase TYK20033
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0033
Heme oxygenase 20033
Tyrosine-protein kinase receptor UFO0022
Mitogen-activated protein kinase 40022
S-adenosylmethionine synthase isoform type-20033
DnaJ homolog subfamily A member 10033
RAC-alpha serine/threonine-protein kinase0033
RAC-beta serine/threonine-protein kinase0033
G protein-coupled receptor kinase 40022
Cytochrome P450 2C190101
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40033
Type-1 angiotensin II receptor0101
Prostaglandin G/H synthase 20022
Tyrosine-protein kinase receptor Tie-10022
Vascular endothelial growth factor receptor 30123
Vascular endothelial growth factor receptor 20438
Dual specificity mitogen-activated protein kinase kinase 20134
Receptor-type tyrosine-protein kinase FLT30235
Bone morphogenetic protein receptor type-1A0033
Activin receptor type-1B0033
TGF-beta receptor type-10033
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20033
Electron transfer flavoprotein subunit beta0033
Tyrosine-protein kinase CSK0033
Glycine--tRNA ligase0033
Mitogen-activated protein kinase kinase kinase 80101
Protein kinase C iota type0033
Exosome RNA helicase MTR40033
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0224
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0224
Serine/threonine-protein kinase mTOR0224
Megakaryocyte-associated tyrosine-protein kinase0022
Tyrosine-protein kinase Tec0033
Tyrosine-protein kinase TXK0022
Tyrosine-protein kinase ABL20033
Tyrosine-protein kinase FRK0033
G protein-coupled receptor kinase 60033
Tyrosine-protein kinase ZAP-700022
Tyrosine-protein kinase SYK0033
26S proteasome regulatory subunit 6B0033
Mitogen-activated protein kinase 80033
Mitogen-activated protein kinase 90033
Dual specificity mitogen-activated protein kinase kinase 40033
Dual specificity mitogen-activated protein kinase kinase 30033
Histamine H2 receptor1001
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0033
Casein kinase I isoform alpha0235
Casein kinase I isoform delta0033
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0224
MAP kinase-activated protein kinase 20033
Cyclin-dependent kinase 80123
Elongation factor Tu, mitochondrial0033
Cysteine--tRNA ligase, cytoplasmic0033
Casein kinase I isoform epsilon0033
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0033
Dual specificity protein kinase CLK10033
Dual specificity protein kinase CLK20033
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0033
Glycogen synthase kinase-3 beta0134
Cyclin-dependent kinase 70033
Cyclin-dependent kinase 90033
Ras-related protein Rab-27A0033
Tyrosine-protein kinase Blk0022
Interleukin-1 receptor-associated kinase 10033
Ribosomal protein S6 kinase alpha-30033
Cytoplasmic tyrosine-protein kinase BMX0022
cAMP-dependent protein kinase catalytic subunit PRKX0022
Serine/threonine-protein kinase Nek20033
Serine/threonine-protein kinase Nek30033
Serine/threonine-protein kinase Nek40022
Tyrosine-protein kinase JAK30123
Dual specificity mitogen-activated protein kinase kinase 60033
Serine/threonine-protein kinase PLK10134
Death-associated protein kinase 10022
LIM domain kinase 10033
LIM domain kinase 20033
Mitogen-activated protein kinase 120123
Mitogen-activated protein kinase 100033
Tyrosine--tRNA ligase, cytoplasmic0033
5'-AMP-activated protein kinase subunit gamma-10033
5'-AMP-activated protein kinase catalytic subunit alpha-20022
Ephrin type-B receptor 30033
Ephrin type-A receptor 50033
Ephrin type-B receptor 40235
Ephrin type-B receptor 10022
Ephrin type-A receptor 40033
Adenylate kinase 2, mitochondrial0033
Adenosine kinase0033
Beta-secretase 10101
Hormonally up-regulated neu tumor-associated kinase0022
Serine/threonine-protein kinase SIK10022
Receptor-interacting serine/threonine-protein kinase 40022
Spike glycoprotein3003
Ras-related protein Rab-100033
Cell division control protein 2 homolog0022
Actin-related protein 30033
Actin-related protein 20033
Calcium-dependent protein kinase 10022
GTP-binding nuclear protein Ran0033
Tubulin alpha-1A chain0022
Casein kinase II subunit alpha0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0022
SRSF protein kinase 20022
Casein kinase I isoform gamma-20033
DNA-dependent protein kinase catalytic subunit0202
Mitogen-activated protein kinase kinase kinase 90022
Serine/threonine-protein kinase PknB0022
Cyclin-dependent kinase 30033
Cyclin-dependent kinase-like 10022
Cyclin-dependent kinase 60134
Cyclin-dependent-like kinase 5 0033
Cyclin-dependent kinase 160033
Cyclin-dependent kinase 170033
ATP-dependent 6-phosphofructokinase, platelet type0033
Synaptic vesicular amine transporter0101
Protein kinase C epsilon type0022
Dual specificity mitogen-activated protein kinase kinase 10235
Angiopoietin-1 receptor0123
Mitogen-activated protein kinase kinase kinase 100022
DNA topoisomerase 2-beta0033
Transcription factor p650101
Protein kinase C theta type0033
Activin receptor type-10033
Macrophage-stimulating protein receptor0033
Focal adhesion kinase 10033
Protein kinase C zeta type0022
Protein kinase C delta type0033
Tyrosine-protein kinase BTK0033
Tyrosine-protein kinase receptor TYRO30022
Cyclin-dependent kinase 180022
Activated CDC42 kinase 10033
Epithelial discoidin domain-containing receptor 10033
Tyrosine-protein kinase ITK/TSK0022
Myotonin-protein kinase0022
Mitogen-activated protein kinase kinase kinase kinase 20033
Mitogen-activated protein kinase kinase kinase 120022
Tyrosine-protein kinase Mer0134
Serine/threonine-protein kinase 40033
5'-AMP-activated protein kinase catalytic subunit alpha-10033
Serine/threonine-protein kinase PAK 10022
Dual specificity mitogen-activated protein kinase kinase 50033
Mitogen-activated protein kinase 70033
Serine/threonine-protein kinase PAK 20033
Serine/threonine-protein kinase 30033
Mitogen-activated protein kinase kinase kinase 10033
cGMP-dependent protein kinase 20022
Integrin-linked protein kinase0033
Rho-associated protein kinase 10033
Non-receptor tyrosine-protein kinase TNK10033
Serine/threonine-protein kinase PRP4 homolog0022
Receptor-interacting serine/threonine-protein kinase 10123
Calcium/calmodulin-dependent protein kinase type II subunit beta0022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0033
Calcium/calmodulin-dependent protein kinase type II subunit delta0033
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0033
Activin receptor type-2B0033
Bone morphogenetic protein receptor type-20033
Protein-tyrosine kinase 60033
cGMP-dependent protein kinase 1 0033
Cyclin-dependent kinase 130033
Calcium/calmodulin-dependent protein kinase type 10022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0033
Protein-tyrosine kinase 2-beta0033
Maternal embryonic leucine zipper kinase0033
Structural maintenance of chromosomes protein 1A0033
Chromodomain-helicase-DNA-binding protein 40033
Peroxisomal acyl-coenzyme A oxidase 10033
Serine/threonine-protein kinase D10022
Serine/threonine-protein kinase 380022
Receptor tyrosine-protein kinase erbB-40123
Ribosomal protein S6 kinase alpha-20022
Ephrin type-A receptor 70022
Delta(24)-sterol reductase0033
Ribosomal protein S6 kinase alpha-10033
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0033
Mitogen-activated protein kinase 110134
Serine/threonine-protein kinase STK110033
Rhodopsin kinase GRK10022
NT-3 growth factor receptor0022
Serine/threonine-protein kinase N10033
Serine/threonine-protein kinase N20033
Mitogen-activated protein kinase 140235
Calcium/calmodulin-dependent protein kinase type IV0033
Mitogen-activated protein kinase kinase kinase 110033
BDNF/NT-3 growth factors receptor0022
Mitogen-activated protein kinase 60022
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0022
Discoidin domain-containing receptor 20134
AP2-associated protein kinase 10033
Myosin light chain kinase 30033
Uncharacterized aarF domain-containing protein kinase 50022
Serine/threonine-protein kinase ULK30011
Serine/threonine-protein kinase SBK10022
Mitogen-activated protein kinase kinase kinase 190022
Putative heat shock protein HSP 90-beta 20033
Serine/threonine-protein kinase TNNI3K0123
Leucine-rich repeat serine/threonine-protein kinase 20022
Serine/threonine-protein kinase MRCK alpha0033
Serine/threonine-protein kinase MRCK gamma0033
Acyl-CoA dehydrogenase family member 100033
Serine/threonine-protein kinase Nek50022
Serine/threonine-protein kinase N30033
Serine/threonine-protein kinase ULK30033
Dual serine/threonine and tyrosine protein kinase0022
Mitogen-activated protein kinase kinase kinase 150022
Uncharacterized protein FLJ452520033
Acyl-CoA dehydrogenase family member 110033
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20033
Serine/threonine-protein kinase TAO10033
STE20-related kinase adapter protein alpha0033
Myosin-140033
AarF domain-containing protein kinase 10033
Serine/threonine-protein kinase tousled-like 20022
Serine/threonine-protein kinase 32C0022
Serine/threonine-protein kinase pim-30022
ATP-dependent RNA helicase DDX420022
Serine/threonine-protein kinase VRK20022
Myosin light chain kinase family member 40022
Homeodomain-interacting protein kinase 10123
Calcium/calmodulin-dependent protein kinase type 1D0022
Mitogen-activated protein kinase kinase kinase kinase 30033
Cyclin-dependent kinase-like 30022
MAP kinase-activated protein kinase 50033
Serine/threonine-protein kinase BRSK20022
Serine/threonine-protein kinase NIM10022
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0022
Serine/threonine-protein kinase ULK20022
Misshapen-like kinase 10022
Serine/threonine-protein kinase DCLK20022
Calcium/calmodulin-dependent protein kinase kinase 10022
Casein kinase I isoform alpha-like0022
Homeodomain-interacting protein kinase 40123
Myosin-IIIa0022
Ankyrin repeat and protein kinase domain-containing protein 10022
Serine/threonine-protein kinase Nek110022
Atypical kinase COQ8A, mitochondrial0033
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0033
Mitogen-activated protein kinase 150033
Serine/threonine-protein kinase Nek90033
Serine/threonine-protein kinase BRSK10022
Serine/threonine-protein kinase 350022
Serine/threonine-protein kinase Nek70033
Rhodopsin kinase GRK70022
Serine/threonine-protein kinase 32A0022
Myosin-IIIb0022
ATP-dependent RNA helicase DDX10033
Dual specificity tyrosine-phosphorylation-regulated kinase 20022
Cyclin-dependent kinase-like 20022
Canalicular multispecific organic anion transporter 10101
Mitogen-activated protein kinase kinase kinase kinase 10033
Serine/threonine-protein kinase Sgk30022
Atypical kinase COQ8B, mitochondrial0022
Aurora kinase B0033
MAP/microtubule affinity-regulating kinase 40033
Calcium/calmodulin-dependent protein kinase type 1G0022
Serine/threonine-protein kinase Nek10033
Cyclin-dependent kinase 150022
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20033
EKC/KEOPS complex subunit TP53RK0033
SRSF protein kinase 10022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0033
Mitogen-activated protein kinase kinase kinase 50033
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0022
Mitogen-activated protein kinase kinase kinase 30033
Eukaryotic translation initiation factor 2-alpha kinase 10033
Serine/threonine-protein kinase RIO10022
MAP kinase-interacting serine/threonine-protein kinase 10022
Serine/threonine-protein kinase RIO20022
Cyclin-dependent kinase 190123
Transient receptor potential cation channel subfamily M member 60022
Testis-specific serine/threonine-protein kinase 10022
Serine/threonine-protein kinase 330022
Nucleolar GTP-binding protein 10033
Serine/threonine-protein kinase D20033
Serine/threonine-protein kinase DCLK30022
NUAK family SNF1-like kinase 20033
RNA cytidine acetyltransferase0033
Serine/threonine-protein kinase SIK20033
Myosin light chain kinase 2, skeletal/cardiac muscle0022
STE20-like serine/threonine-protein kinase 0033
Serine/threonine-protein kinase TAO30033
Homeodomain-interacting protein kinase 20123
Tyrosine-protein kinase Srms0022
Homeodomain-interacting protein kinase 30123
Serine/threonine-protein kinase PLK30123
dCTP pyrophosphatase 10033
Dual specificity protein kinase CLK40033
MAP kinase-interacting serine/threonine-protein kinase 20123
Serine/threonine-protein kinase Nek60022
Casein kinase I isoform gamma-10033
Serine/threonine-protein kinase PAK 60022
SNF-related serine/threonine-protein kinase0022
Serine/threonine-protein kinase LATS20022
Serine/threonine-protein kinase 360022
Phenylalanine--tRNA ligase beta subunit0033
Isoleucine--tRNA ligase, mitochondrial0022
BMP-2-inducible protein kinase0033
Obg-like ATPase 10033
Midasin0033
Interleukin-1 receptor-associated kinase 40033
Serine/threonine-protein kinase 32B0022
Mitogen-activated protein kinase kinase kinase 200134
Cyclin-dependent kinase 120033
Serine/threonine-protein kinase PLK20123
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130033
Serine/threonine-protein kinase MARK10022
Serine/threonine-protein kinase pim-20033
Serine/threonine-protein kinase PAK 50022
Serine/threonine-protein kinase 260033
eIF-2-alpha kinase GCN20022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0033
Serine/threonine-protein kinase NLK0033
Phosphatidylinositol 4-kinase beta0022
Serine/threonine-protein kinase 17A0022
STE20/SPS1-related proline-alanine-rich protein kinase0022
Ephrin type-A receptor 60022
5'-AMP-activated protein kinase subunit gamma-20033
Serine/threonine-protein kinase TBK10033
Septin-90033
Death-associated protein kinase 20022
Ribosomal protein S6 kinase alpha-60033
TRAF2 and NCK-interacting protein kinase0033
Serine/threonine-protein kinase tousled-like 10022
Serine/threonine-protein kinase TAO20033
Long-chain-fatty-acid--CoA ligase 50033
ALK tyrosine kinase receptor0022
SRSF protein kinase 30022
Serine/threonine-protein kinase ICK0033
Cyclin-dependent kinase 11A0022
Aurora kinase C0022
Calcium/calmodulin-dependent protein kinase type II subunit alpha0022
RAC-gamma serine/threonine-protein kinase0033
Serine/threonine-protein kinase 38-like0033
Microtubule-associated serine/threonine-protein kinase 10022
Serine/threonine-protein kinase SIK30033
Mitogen-activated protein kinase kinase kinase 20033
Thyroid hormone receptor-associated protein 30033
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0033
Mitogen-activated protein kinase kinase kinase kinase 50033
Receptor-interacting serine/threonine-protein kinase 30134
Serine/threonine-protein kinase MRCK beta0033
Interleukin-1 receptor-associated kinase 30033
Serine/threonine-protein kinase 240022
Casein kinase I isoform gamma-30033
Mitogen-activated protein kinase kinase kinase 40033
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, 2-oxoglutarate Oxygenase4004
Parkin1001
bromodomain adjacent to zinc finger domain 2B2002
alpha-galactosidase1001
lysosomal alpha-glucosidase preproprotein2002
cytochrome P450 2C19 precursor1001
chromobox protein homolog 12002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
DNA polymerase kappa isoform 11001
muscarinic acetylcholine receptor M11001
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Glutamate receptor 10102
Glutamate receptor 30102
Glutamate receptor 40102
Glutamate receptor ionotropic, kainate 10102
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Glutamate receptor ionotropic, NMDA 1 0406
Neuronal acetylcholine receptor subunit alpha-70101
Glutamate receptor ionotropic, kainate 20102
Glutamate receptor ionotropic, kainate 30102
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Glutamate receptor ionotropic, NMDA 2A 0305
Glutamate receptor ionotropic, NMDA 2B0305
Glutamate receptor ionotropic, NMDA 2C0306
Glutamate receptor ionotropic, kainate 40102
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, NMDA 2B0303
Glutamate receptor ionotropic, NMDA 2C0202
Gamma-aminobutyric acid receptor subunit alpha-60101
G protein-coupled receptor GPR350011
Glutamate receptor ionotropic, NMDA 2D0305
Glutamate receptor ionotropic, kainate 50102
Vesicular glutamate transporter 30101
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0305
G-protein coupled receptor 350213
Histamine H3 receptor0011
Glutamate receptor ionotropic, NMDA 3A0305
ATP-dependent phosphofructokinase3003
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
phosphopantetheinyl transferase2002
nuclear receptor ROR-gamma isoform 12002
Chain A, NAD-dependent deacetylase0101
histone acetyltransferase KAT2A isoform 11001
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10202
Protein mono-ADP-ribosyltransferase PARP150101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Sodium-dependent serotonin transporter0202
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0012
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Sigma non-opioid intracellular receptor 10101
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
thioredoxin reductase3003
GALC protein1001
IDH11001
beta-2 adrenergic receptor1001
Bloom syndrome protein isoform 12002
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Chain A, AKAP9-BRAF fusion protein0101
Membrane-associated progesterone receptor component 10022
Pirin0101
GTPase KRas0101
Myosin-100022
Dual specificity mitogen-activated protein kinase kinase 40011
Heat shock factor protein 10101
Aspartyl/asparaginyl beta-hydroxylase0101
Serine/threonine-protein kinase ATR0022
Cyclin-dependent kinase 100011
Rab-like protein 30022
Dual specificity testis-specific protein kinase 20022
Smad32002
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20101
USP1 protein, partial1001
PPM1D protein1001
melanocortin receptor 40112
Tyrosine-protein kinase ABL10101
Platelet-derived growth factor receptor beta0101
Cytochrome P450 3A40101
5-hydroxytryptamine receptor 1A0101
Aromatase0101
G1/S-specific cyclin-D10101
Cyclin-C0112
5-hydroxytryptamine receptor 2A0101
5-hydroxytryptamine receptor 2C0101
Bifunctional epoxide hydrolase 20101
5-hydroxytryptamine receptor 70101
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Alpha-synuclein1001
5-hydroxytryptamine receptor 2B0101
Carbonic anhydrase 70102
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60101
Protein delta homolog 10011
MAP kinase-activated protein kinase 30011
Carbonic anhydrase 90102
Vascular endothelial growth factor receptor 20101
ATP-dependent RNA helicase DHX300011
Poly [ADP-ribose] polymerase tankyrase-20011
RuvB-like 20112
RuvB-like 10101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
GLS protein1001
thioredoxin glutathione reductase1001
arylsulfatase A1001
peripheral myelin protein 22 isoform 11001
flap endonuclease 11001
DNA polymerase iota isoform a (long)1001
M-phase phosphoprotein 81001
Carbonic anhydrase 120001
Dihydrofolate reductase0202
Plasma kallikrein0001
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Carbonic anhydrase 30001
Stromelysin-10101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Carbonic anhydrase 60001
Substance-P receptor0101
Carbonic anhydrase 5A, mitochondrial0001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 130001
Carbonic anhydrase 140001
Phospholipase A-2-activating protein0101
Carbonic anhydrase 5B, mitochondrial0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]