Didecyldimethylammonium chloride (DDAC) is a quaternary ammonium compound widely used as a cationic surfactant. It is typically synthesized through the reaction of dodecyl chloride with dimethylamine. DDAC exhibits antimicrobial properties, making it effective as a disinfectant and biocide in various applications, including household cleaners, personal care products, and industrial processes. Its effectiveness against bacteria, fungi, and viruses stems from its ability to disrupt cell membranes. Research on DDAC focuses on understanding its efficacy against specific microorganisms, optimizing its application for different purposes, and assessing its potential environmental impact. The compound is studied to determine its safety for human health and to develop more sustainable alternatives. '
| ID Source | ID |
|---|---|
| PubMed CID | 23558 |
| CHEMBL ID | 224987 |
| CHEBI ID | 79935 |
| SCHEMBL ID | 20265 |
| MeSH ID | M0317134 |
| Synonym |
|---|
| slaoff 91 |
| ammonium, didecyldimethyl-, chloride |
| btco 1010 |
| aliquat 203 |
| quartamin d 10p |
| quaternium-12 |
| bardac 22 |
| d 10p |
| arquad 210-50 |
| odex q |
| timbercote 2000 |
| btc 1010 |
| h 130 (molluscicide) |
| britewood q |
| astop |
| nissan cation 2db |
| ddc 80 |
| epa pesticide chemical code 069149 |
| bardac 2250 |
| maquat 4480e |
| einecs 230-525-2 |
| bio-dac |
| btc 99 |
| didecyl dimethyl ammonium chloride |
| caswell no. 331a |
| ddac |
| dodigen 1881 |
| bio-dac 50-22 |
| calgon h 130 |
| querton 210cl |
| bardac 2280 |
| dimethyldidecylammonium chloride |
| tret-o-lite xc 507 |
| bardac 2270e |
| quartamin d 10e |
| c22h48cln |
| n-decyl-n,n-dimethyl-1-decanaminium chloride |
| didecyldimethylammonium chloride |
| arquad 10 |
| calgon h130 |
| n-decyl-n,n-dimethyl 1-decanaminium chloride |
| querton 2100l |
| didecyl(dimethyl)ammonium |
| 7173-51-5 |
| quaternium 12 |
| bardac-22 |
| n-decyl-n,n-dimethyldecan-1-aminium chloride |
| 1-decanaminium, n-decyl-n,n-dimethyl-, chloride |
| CHEMBL224987 |
| chebi:79935 , |
| didecyl(dimethyl)azanium chloride |
| D07822 |
| alfa bergamon (tn) |
| A837307 |
| didecyl(dimethyl)ammonium chloride |
| dtxsid9032537 , |
| cas-7173-51-5 |
| NCGC00254240-01 |
| tox21_300598 |
| dtxcid7012537 |
| acticide |
| septapav khs 70 |
| cation ddc-80 |
| dairyland brand chg teat dip |
| arquad 210-85e |
| macrotrol mt 200 |
| microbiocide b 74 |
| fentacare 1021-80 |
| nissan cation 2db500e |
| cation ddc 50 |
| jxn40o9y9b , |
| n,n-didecyl-n,n-dimethylammonium chloride |
| hsdb 7611 |
| stenquat 1010 |
| didecyldimethylammounium chloride |
| aq 210 |
| unii-jxn40o9y9b |
| arquad 210-80 |
| h 130 |
| 2db500e |
| britewood xl |
| cation ddc |
| nissan cation 2db800e |
| asepas 3 |
| arquad 210-80e |
| bardac 2240 |
| new des 50 |
| k-sanit bp 80 |
| arquad 210-50e |
| ec 230-525-2 |
| kleengrow |
| acticide ddq 40 |
| kamin rm 2d50a |
| catiogen ddm |
| catiogen ddm-pg |
| 1-decanaminium, n-decyl-n,n-dimethyl-, chloride (1:1) |
| microbiocide n 750 |
| sporekill |
| btc 2250 |
| acticide ddq |
| m 21080 |
| arquad 210 |
| FT-0629457 |
| didecyldimonium chloride |
| didecyldimethylammonium chlorid |
| didecyl dimethyl ammonium chloride [hsdb] |
| didecyldimonium chloride [inci] |
| didecyldimethylammonium chlorid [who-dd] |
| maquat 4450-e |
| dicapryldimonium chloride |
| didecyldimethylammonium chloride [mart.] |
| didecyldimethylammonium chloride [mi] |
| AKOS015901447 |
| didecyldimethyl ammonium chloride |
| RUPBZQFQVRMKDG-UHFFFAOYSA-M |
| SCHEMBL20265 |
| didecyl dimethylammonium chloride |
| W-104509 |
| mfcd00066262 |
| didecyldimethylammonium chloride, analytical standard |
| ddac-c10; didecyldimethylammonium-chloride |
| didecyldimethylammonium chloride 100 microg/ml in acetonitrile |
| Q418930 |
| CS-W022921 |
| n-decyl-n,n-dimethyldecan-1-aminium (chloride) |
| didecyl(dimethyl)azanium;chloride |
| n-decyl-n,n-dimethyldecan-1-aminiumchloride |
| n-decyl-n,n-dimethyldecan-1-ammonium chloride |
| EN300-7386480 |
| bis(decyl)dimethylazanium chloride |
| HY-W042181 |
| surface disinfectant spray |
| chloroqcare antiseptic hand care |
| steri hand sanitizer without washing |
| alfa bergamon |
| usepa/opp pesticide code: 069149 |
| okgo disinfectant |
| didecyldimethylammonium chloride (mart.) |
| surface disinfectant |
| Class | Description |
|---|---|
| organic molecular entity | Any molecular entity that contains carbon. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 62.7829 | 0.0025 | 41.7960 | 15,848.9004 | AID1347395; AID1347397; AID1347398 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 49.2911 | 3.1890 | 29.8841 | 59.4836 | AID1224846; AID1224894 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.1142 | 0.0060 | 38.0041 | 19,952.5996 | AID1159521; AID1159523 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 57.8921 | 0.1737 | 34.3047 | 61.8120 | AID1346859; AID1346924; AID1347035 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 57.8921 | 0.1737 | 34.3047 | 61.8120 | AID1346859; AID1346924; AID1347035 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 0.9878 | 0.0007 | 14.5928 | 83.7951 | AID1259369; AID1259392 |
| AR protein | Homo sapiens (human) | Potency | 31.5603 | 0.0002 | 21.2231 | 8,912.5098 | AID1259243; AID1259247; AID743035; AID743036; AID743042; AID743053; AID743054; AID743063 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 27.3060 | 0.0133 | 26.9810 | 70.7614 | AID1346978 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 46.0782 | 0.0006 | 57.9133 | 22,387.1992 | AID1259377; AID1259378; AID1259394 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 36.3152 | 0.0010 | 22.6508 | 76.6163 | AID1224838; AID1224839; AID1224893 |
| progesterone receptor | Homo sapiens (human) | Potency | 30.6379 | 0.0004 | 17.9460 | 75.1148 | AID1346784; AID1346795 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 31.4853 | 0.0002 | 14.3764 | 60.0339 | AID720691; AID720692; AID720719 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 18.8402 | 0.0030 | 41.6115 | 22,387.1992 | AID1159552; AID1159553; AID1159555 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 13.7290 | 0.0008 | 17.5051 | 59.3239 | AID1159527; AID1159531 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 19.0319 | 0.0015 | 30.6073 | 15,848.9004 | AID1224841; AID1224842; AID1224848; AID1224849; AID1259401; AID1259403 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 61.6448 | 0.3758 | 27.4851 | 61.6524 | AID743217; AID743220; AID743239 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 30.6379 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 50.8627 | 0.0002 | 29.3054 | 16,493.5996 | AID1259244; AID1259248; AID1259383; AID743069; AID743075; AID743079; AID743080; AID743091 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 61.6448 | 0.0010 | 24.5048 | 61.6448 | AID743212; AID743215; AID743227 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 59.4102 | 0.0010 | 19.4141 | 70.9645 | AID743094; AID743140; AID743191 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 37.2684 | 0.0237 | 23.2282 | 63.5986 | AID743222; AID743223 |
| caspase-3 | Homo sapiens (human) | Potency | 27.3060 | 0.0133 | 26.9810 | 70.7614 | AID1346978 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 24.3365 | 0.0017 | 23.8393 | 78.1014 | AID743083 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 61.5361 | 0.0016 | 28.0151 | 77.1139 | AID1224895; AID1259385 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 57.1325 | 0.1434 | 27.6121 | 59.8106 | AID1159516; AID1159519 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 30.1475 | 0.1549 | 17.8702 | 43.6557 | AID1346877 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 51.9536 | 19.7391 | 45.9784 | 64.9432 | AID1159509; AID1159518 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 15.7289 | 0.0578 | 21.1097 | 61.2679 | AID1159526; AID1159528 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 38.4184 | 0.0391 | 47.5451 | 146.8240 | AID1224845; AID1224896 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 27.3060 | 0.0067 | 23.4960 | 68.5896 | AID1346980 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 27.3060 | 0.0067 | 23.4960 | 68.5896 | AID1346980 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 10.7132 | 0.0003 | 23.4451 | 159.6830 | AID743065; AID743067 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 51.9536 | 0.0420 | 27.3789 | 61.6448 | AID743210; AID743228 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 68.5896 | 0.0006 | 27.2152 | 1,122.0200 | AID743202 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 30.6379 | 0.0015 | 57.7890 | 15,848.9004 | AID1259244 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 68.5896 | 0.0023 | 19.5956 | 74.0614 | AID651631; AID720552 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 30.6379 | 0.0015 | 51.7393 | 15,848.9004 | AID1259244 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID278510 | Antibacterial activity against 10^5 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID1082713 | Antifungal activity against Laetiporus sulphureus BCRC 35305 (wood decay fungi) assessed as reduction of fungi mycelium growth at 100 ug/ml | 2012 | Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1 | Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents. |
| AID278516 | Loss of membrane integrity in Staphylococcus aureus ATCC 6538 at above 4.5 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID278517 | Induction of membrane collapse in Staphylococcus aureus ATCC 6538 at 12 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID278514 | Antibacterial activity against 10^9 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID1082712 | Antifungal activity against Gloeophyllum trabeum BCRC 31614 (wood decay fungi) assessed as reduction of fungi mycelium growth at 100 ug/ml | 2012 | Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1 | Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents. |
| AID1322503 | Induction of biofilm disruption in Escherichia coli after 24 hrs by confocal laser-scanning microscopy | |||
| AID278520 | Intracellular coagulation in Staphylococcus aureus ATCC 6538 at tested concentrations 4.5, 9, 12 and 15 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID1322502 | Induction of biofilm disruption in Staphylococcus aureus after 24 hrs by confocal laser-scanning microscopy | |||
| AID278512 | Antibacterial activity against 10^7 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID1082298 | Fungistatic activity against Fusarium oxysporum AM 13 assessed as effect on diameter of fungal growth zone | 2011 | Journal of agricultural and food chemistry, Jun-08, Volume: 59, Issue:11 | Fungistatic activity of bicyclo[4.3.0]-γ-lactones. |
| AID1082714 | Antifungal activity against Trametes versicolor BCRC 35253 wood decay fungi assessed as reduction of fungi mycelium growth at 100 ug/ml | 2012 | Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1 | Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents. |
| AID1082715 | Antifungal activity against Lenzites betulinus BCRC 35296 assessed as reduction of fungi mycelium growth at 100 ug/ml | 2012 | Journal of agricultural and food chemistry, Jan-11, Volume: 60, Issue:1 | Phytochemicals from Cunninghamia konishii Hayata act as antifungal agents. |
| AID1092272 | Bactericidal activity against Escherichia coli IFO 3806 assessed as log10 reduction in viable cell count at 2.8 uM up to 120 min by agar dilution test | 1994 | Antimicrobial agents and chemotherapy, May, Volume: 38, Issue:5 | Synthesis and antimicrobial activity of dimethyl- and trimethyl-substituted phosphonium salts with alkyl chains of various lengths. |
| AID278519 | Induction of autolysis in Staphylococcus aureus ATCC 6538 at 9 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID278511 | Antibacterial activity against 10^6 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID278513 | Antibacterial activity against 10^8 CFU/ml Staphylococcus aureus ATCC 6538 after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID278518 | Reduction of cell count in Staphylococcus aureus ATCC 6538 between 6 to 18 hrs exposure | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| AID1082297 | Fungistatic activity against Fusarium tricinctum AM 16 assessed as effect on diameter of fungal growth zone | 2011 | Journal of agricultural and food chemistry, Jun-08, Volume: 59, Issue:11 | Fungistatic activity of bicyclo[4.3.0]-γ-lactones. |
| AID1082296 | Fungistatic activity against Penicillium citrinum AM 354 assessed as effect on diameter of fungal growth zone | 2011 | Journal of agricultural and food chemistry, Jun-08, Volume: 59, Issue:11 | Fungistatic activity of bicyclo[4.3.0]-γ-lactones. |
| AID1082299 | Fungistatic activity against Fusarium culmorum AM 282 assessed as effect on diameter of fungal growth zone | 2011 | Journal of agricultural and food chemistry, Jun-08, Volume: 59, Issue:11 | Fungistatic activity of bicyclo[4.3.0]-γ-lactones. |
| AID1082300 | Fungistatic activity against Aspergillus ochraceus AM 456 assessed as effect on diameter of fungal growth zone | 2011 | Journal of agricultural and food chemistry, Jun-08, Volume: 59, Issue:11 | Fungistatic activity of bicyclo[4.3.0]-γ-lactones. |
| AID278515 | Internal Potassium leakage in Staphylococcus aureus ATCC 6538 at 9 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Action of disinfectant quaternary ammonium compounds against Staphylococcus aureus. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (59.88) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||