Compounds > 2,2-dimethyl-1,3-dioxolane-4-methanol
Page last updated: 2024-12-05

2,2-dimethyl-1,3-dioxolane-4-methanol

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Description

2,2-dimethyl-1,3-dioxolane-4-methanol: RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID7528
CHEMBL ID3342436
SCHEMBL ID3991160
SCHEMBL ID23556
MeSH IDM0082565

Synonyms (133)

Synonym
AC-364
EN300-20586
d-acetone glycerol
(2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol
1,3-dioxolane-4-methanol, 2,2-dimethyl-, (s)-
2,2-dimethyl-5-hydroxymethyl-1,3-dioxolane
2,2-dimethyl-1,3-dioxolan-4-yl methanol
alpha,beta-isopropylideneglycerol
ai3-03547
acetone, cyclic (hydroxymethyl)ethylene acetal
glycerol, 1,2-o-isopropylidene
2,2-dimethyl-4-oxymethyl-1,3-dioxolane
einecs 202-888-7
2,2-dimethyl-1,3-dioxolan-4-ylmethanol
brn 0104465
2,2-dimethyl-1,3-dioxolane-4-methanol
nsc 59720
1,2-o,o-isopropylideneglycerin
4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane
glycerol acetonide (van)
2,2-dimethyl-4-(hydroxymethyl)-1,3-dioxacyclopentane
glycerol dimethylketal
1,2-o-isopropylideneglycerol
glycerol,2-o-isopropylidene
2,2-dimethyl-4-hydroxymethyldioxolane
isopropylidene glycerol
nsc59720
2,3-o-isopropylideneglycerol
glycerolacetone
2,3-isopropylideneglycerol
GIE ,
.alpha.,.beta.-isopropylideneglycerol
1,o-isopropylideneglycerin
2,3-dioxacyclopentane
2,3-dioxolan-4-yl methanol
2,3-(isopropylidenedioxy)propanol
4-hydroxymethyl-2,3-dioxolane
acetone monoglycerol ketal
glycerinisopropylidene ether
wln: t5o cotj b1 b1 d1q
nsc-59720
1,2-isopropylideneglycerol
100-79-8
solketal
1,2-isopropylideneglycerin
glycerol acetonide
(2,2-dimethyl-1,3-dioxolan-4-yl)methanol
1,3-dioxolane-4-methanol, 2,2-dimethyl-
dl-1,2-isopropylideneglycerol, >=97.0%
2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane
D0710
E10100
SCHEMBL3991160
STK803305
AKOS000120075
unii-3xk098o8zw
3xk098o8zw ,
ec 202-888-7
5-19-02-00362 (beilstein handbook reference)
2,2-dimethyl-1,3-dioxolan-4-yl methanol [iupac]
BBL012719
FT-0609251
FT-0602207
FT-0605040
(-)-2,2-dimethyl-1,3-dioxolane-4-methanol
dl-1,2-isopropylideneglycerol
isopropylidene glycerol [mi]
acetone glycerin ketal
AM666
36543-79-0
AKOS022060550
AM90170
SCHEMBL23556
(2,2-dimethyl-[1,3]dioxolan-4-yl) -methanol
2,3-(dimethylmethylenedioxy)-1-propanol
2,2-dimethyl-1,3-dioxolane4-methanol
2,2-dimethyl-[1,3]dioxolane-4-methanol
rac-(2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol
2,2-dimethyl-1,3-dioxolane4-methanol (solketal)
1,2-isopropylidene glycerol
dimethyl-1,3-dioxolane-4-methanol
dl-1,2-isoproylideneglycerol
4-hydroxymethyl-2,2-dimethyl-1,3-dioxolan
(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol
1,2-o-isopropylidene glycerol
(2,2-dimethyl-1,3-dioxolan-4yl)methanol
2,2-dimethyl-1,3-dioxolane-4-methanol (solketal)
2,2-dimethyl-4-hydroxymethyl-1,3-dioxolan
(4rs)-2,2-dimethyl 1.3-dioxolane-4-methanol
2,2dimethyl-1,3-dioxolane-4-methanol (solketal)
[(4r/s)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol
(rac)-2,2-dimethyl-[1,3]-dioxolane-4-methanol
(2,2-dimethyl[1,3]dioxolan-4-yl)methanol
rac-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol
2,2-dimethyl-1,3-dioxolan-4-methanol
1.2-isopropylidene-rac-glycerol
1,2-isopropylidene-rac-glycerol
SY017180
mfcd00063239
(+/-)-2,2-dimethyl-1,3-dioxolane-4-methanol
(+/-)-2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane
racemic solketal
dl-.alpha.,.beta.-isopropylideneglycerol
(.+/-.)-1,2-o-isopropylideneglycerol
(rs)-solketal
(4rs)-2,2-dimethyl-1,3-dioxolane-4-methanol
(.+/-.)-glycerol 1,2-acetonide
W-108939
r-(-)-sollketal
mfcd00003213
DTXSID9021845
mfcd00063238
74300-14-4
dimethyl-4-hydroxymethyl-1,3-dioxolane
CHEMBL3342436
F0001-0027
(r)-(?)-2,2-dimethyl-1,3-dioxolane-4-methanol
CS-W018546
Q2968854
SY017621
benzene, 1-fluoro-3-(1-propyn-1-yl)-
1436560-86-9
2,2-dimethyl-1,3-dioxolane-13c3-4-methanol
AS-46670
BCP26373
(-)-2,3-o-isopropylidene-sn-glycerol
SY010573
FT-0667422
(r,s)-2,2-dimethyl-1,3-dioxolane-4-methanol
2,2-dimethyl-1,3-dioxolane-4-methanol solketal
glycerolacetonide
(rs)-2,2-dimethyl-1,3-dioxolane-4-methanol-d5
Z104479028
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (1 Product(s))

Product Categories

Product CategoryProducts
Baby & Kids Products1

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
Dapple Baby Safe Foaming Dish Power Spray Fragrance Free -- 16.9 fl ozDappleBaby & Kids Productsisopropylidene glycerol, citric acid, citric acid, lauramine oxide, glycerin, sodium bicarbonate, sodium hydroxide2024-11-29 10:47:42

Bioassays (21)

Assay IDTitleYearJournalArticle
AID1163937Antioxidant activity assessed as inhibition of Fe2+/ascorbic acid-induced linoleic acid peroxidation at 10 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163923Antioxidant activity assessed as ABTS radical scavenging activity at 25 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163916Antioxidant activity assessed as DPPH radical scavenging activity at 50 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163929Antioxidant activity assessed as nitric acid scavenging activity by measuring NaNO2 at 50 uM by spectrophotometry2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163933Antioxidant activity assessed as hydroxyl radical scavenging activity2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163922Antioxidant activity assessed as ABTS radical scavenging activity at 10 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163931Antioxidant activity assessed as nitric acid scavenging activity by measuring NaNO2 at 500 uM by spectrophotometry2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163930Antioxidant activity assessed as nitric acid scavenging activity by measuring NaNO2 at 100 uM by spectrophotometry2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163932Antioxidant activity assessed as ferric ion reducing activity at 10 to 500 uM after 40 mins by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163938Antioxidant activity assessed as inhibition of Fe2+/ascorbic acid-induced linoleic acid peroxidation at 50 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163935Antioxidant activity assessed as inhibition of Fe2+/ascorbic acid-induced linoleic acid peroxidation at 1 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163924Antioxidant activity assessed as ABTS radical scavenging activity at 50 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163928Antioxidant activity assessed as nitric acid scavenging activity by measuring NaNO2 at 10 uM by spectrophotometry2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163925Antioxidant activity assessed as ABTS radical scavenging activity at 100 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163926Antioxidant activity assessed as ABTS radical scavenging activity at 500 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163939Antioxidant activity assessed as inhibition of Fe2+/ascorbic acid-induced linoleic acid peroxidation at 100 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163917Antioxidant activity assessed as DPPH radical scavenging activity at 100 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163940Antioxidant activity assessed as inhibition of Fe2+/ascorbic acid-induced linoleic acid peroxidation at 500 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163915Antioxidant activity assessed as DPPH radical scavenging activity at 10 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163936Antioxidant activity assessed as inhibition of Fe2+/ascorbic acid-induced linoleic acid peroxidation at 5 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
AID1163918Antioxidant activity assessed as DPPH radical scavenging activity at 500 uM by spectrophotometry relative to control2014Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21
Organochalcogen compounds from glycerol: synthesis of new antioxidants.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (27.27)18.7374
1990's2 (9.09)18.2507
2000's7 (31.82)29.6817
2010's6 (27.27)24.3611
2020's1 (4.55)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 35.15

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index35.15 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.78 (4.65)
Search Engine Demand Index42.84 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (35.15)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbon monoxide
Carbon Monoxide: Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed). carbon monoxide : A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.		2.2510carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
glycerol
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.		3.3160alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.0710alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
pqq cofactor
PQQ Cofactor: A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES.. pyrroloquinoline quinone : A pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions.		2.0110orthoquinones;
pyrroloquinoline cofactor;
tricarboxylic acid		anti-inflammatory agent;
antioxidant;
cofactor;
water-soluble vitamin (role)
1-anilino-8-naphthalenesulfonate
1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.		2.4420aminonaphthalene;
naphthalenesulfonic acid		fluorescent probe
camphor, (+-)-isomer
[no description available]		2.0210bornane monoterpenoid;
cyclic monoterpene ketone		plant metabolite
tyramine
[no description available]		1.9810monoamine molecular messenger;
primary amino compound;
tyramines		EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter
dimethylphenylpiperazinium iodide
Dimethylphenylpiperazinium Iodide: A selective nicotinic cholinergic agonist used as a research tool. DMPP activates nicotinic receptors in autonomic ganglia but has little effect at the neuromuscular junction.		1.9810N-arylpiperazine;
organic iodide salt;
piperazinium salt;
quaternary ammonium salt		nicotinic acetylcholine receptor agonist
aspartic acid
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.. aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent. L-aspartic acid : The L-enantiomer of aspartic acid.		2.0410aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
sucrose
Saccharum: A plant genus of the family POACEAE widely cultivated in the tropics for the sweet cane that is processed into sugar.		6.9810glycosyl glycosidealgal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent
carbostyril
Quinolones: A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.. quinolin-2(1H)-one : A quinolone that is 1,2-dihydroquinoline substituted by an oxo group at position 2.		2.0110monohydroxyquinoline;
quinolone		bacterial xenobiotic metabolite
alpha-pinene
[no description available]		2.0210pineneplant metabolite
triethylamine
[no description available]		1.9610tertiary amine
isomaltose
[no description available]		1.9810
glycerylphosphorylcholine
Glycerylphosphorylcholine: A component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed)		1.9610glycerophosphocholine
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		2.0110dihydrogen
alkenes
[no description available]		3.3160
1-hexadecyl-2-acetyl-glycero-3-phosphocholine
Platelet Activating Factor: A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.. 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine : A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.		1.96102-acetyl-1-alkyl-sn-glycero-3-phosphocholineantihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent
erythritol
[no description available]		1.9810butane-1,2,3,4-tetrolantioxidant;
human metabolite;
plant metabolite
arabinose
[no description available]		1.9510L-arabinoseEscherichia coli metabolite;
mouse metabolite
isomaltulose
6-O-alpha-D-glucopyranosyl-D-fructofuranose : A glycosylfructose that is D-fructofuranose attached to a alpha-D-glucopyranosyl unit at position 6 via a glycosidic linkage. It is found in honey and sugarcane.		6.9810glycosylfructoseanimal metabolite;
plant metabolite;
sweetening agent
sulfur
Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.		2.2510chalcogen;
nonmetal atom		macronutrient
phosphoramidite
phosphoramidite: structure in first source. phosphoramidite : A compound with the general formula (RO)2PNR2. Phosphoramidites can be regarded as phosphites that have an NR2 instead of an OH group, or as amides of phosphorous acid.		2.0710
oligonucleotides
[no description available]		2.0710
ConditionIndicatedRelationship StrengthStudiesTrials