Page last updated: 2024-12-07

basic blue 99

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Basic Blue 99: causes contact dermatitis; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID93377
SCHEMBL ID456881
MeSH IDM0180655

Synonyms (23)

Synonym
basic blue 99
einecs 268-544-3
benzenaminium, 3-((4-amino-6-bromo-5,8-dihydro-1-hydroxy-8-imino-5-oxo-2-naphtha- lenyl)amino)-n,n,n-trimethyl-, chloride
benzenaminium, 3-((4-amino-6-bromo-5,8-dihydro-1-hydroxy-8-imino-5-oxo-2-naphthalenyl)amino)-n,n,n-trimethyl-, chloride (1:1)
ci 56059
3-((4-amino-6-bromo-5,8-dihydro-1-hydroxy-8-imino-5-oxo-2-naphtyl)amino)-n,n,n-trimethylanilinium chloride
unii-p0u7vbc51e
3-((4-amino-6-bromo-5,8-dihydro-1-hydroxy-8-imino-5-oxo-2-naphtha- lenyl)amino)-n,n,n-trimethylbenzenaminium chloride
c.i. basic blue 99
p0u7vbc51e ,
68123-13-7
benzenaminium, 3-((4-amino-6-bromo-5,8-dihydro-1-hydroxy-8-imino-5-oxo-2-naphthalenyl)amino)-n,n,n-trimethyl-, chloride
FT-0622581
SCHEMBL456881
arianor steel blue 306004
jarocol steel blue
basic blue 99 [inci]
basicblue99
DTXSID60874042
[3-[(4,8-diamino-6-bromo-5-hydroxy-1-oxonaphthalen-2-ylidene)amino]phenyl]-trimethylazanium;chloride
Q27285971
arianor steel blue
CS-0434156

Research Excerpts

Overview

Basic Blue 99 is a direct, nonoxidative hair colorant used in temporary and semipermanent hair dyes.

ExcerptReferenceRelevance
"Basic Blue 99 is a direct, nonoxidative hair colorant used in temporary and semipermanent hair dyes. "( Final report on the safety assessment of Basic Blue 99.
, 2007
)
2.05

Toxicity

ExcerptReferenceRelevance
" The toxic mode of action of Basic Blue 99 seems to be the induction of cell death, without genotoxic effects, but while the necrotic pathway is observed in HaCaT monolayer cell culture, was apoptosis seen in the Equivalent Human Epidermis (EHE) model."( Immortalized equivalent human epidermis as a platform to evaluation hair dyes toxicity: Efficiency comparison between 3D and monolayer culture.
Dorta, DJ; Maria-Engler, SS; Mini, CA; Oliveira, DP, 2020
)
0.85
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (4 Product(s))

Product Categories

Product CategoryProducts
Beauty & Personal Care4

Products

ProductBrandCategoryCompounds Matched from IngredientsDate Retrieved
Tints of Nature Henna Cream Hair Color Black -- 2.46 fl ozTints of NatureBeauty & Personal Careorange, citric acid, chamomile, ascorbic acid, basic blue 99, benzyl alcohol, citric acid, tocopherol, ethylhexylglycerin, tocopherol, henna, limonene, phenoxyethanol, sodium benzoate, sodium sulfite, triethanolamine, urea2024-11-29 10:47:42
Tints of Nature Henna Cream Hair Color Golden Blonde -- 2.46 fl ozTints of NatureBeauty & Personal Careorange, citric acid, chamomile, ascorbic acid, basic blue 99, benzyl alcohol, citric acid, tocopherol, ethylhexylglycerin, tocopherol, henna, limonene, phenoxyethanol, sodium benzoate, sodium sulfite, triethanolamine, urea2024-11-29 10:47:42
Tints of Nature Henna Cream Hair Color Golden Brown -- 2.46 fl ozTints of NatureBeauty & Personal Careorange, citric acid, chamomile, ascorbic acid, basic blue 99, benzyl alcohol, citric acid, tocopherol, ethylhexylglycerin, tocopherol, henna, limonene, phenoxyethanol, sodium benzoate, sodium sulfite, triethanolamine, urea2024-11-29 10:47:42
Tints of Nature Henna Cream Hair Color Light Brown -- 2.46 fl ozTints of NatureBeauty & Personal Careorange, citric acid, chamomile, ascorbic acid, basic blue 99, benzyl alcohol, citric acid, tocopherol, ethylhexylglycerin, tocopherol, henna, limonene, phenoxyethanol, sodium benzoate, sodium sulfite, triethanolamine, urea2024-11-29 10:47:42

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's2 (20.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 35.05

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index35.05 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index42.51 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (35.05)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (20.00%)6.00%
Case Studies4 (40.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (40.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]