sodium acetate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Occurs in Manufacturing Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

sodium diacetate: *acetates [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	15820984
MeSH ID	M0028799

Synonyms (4)

Synonym
sodium diacetate
AKOS015893046
sodium;diacetate
AMY37172

Research Excerpts

Toxicity

Excerpt	Reference	Relevance
"Butylparaben sodium (BP), sodium diacetate (SDA) and potassium sorbate (PS) are safe and internationally recognized preservatives."	( Comparative toxic effects of butylparaben sodium, sodium diacetate and potassium sorbate to Dunaliella tertiolecta and HL7702 cells. Chen, HH; Jiang, JG; Shang, Y; Xu, XL, 2017)	0.46
" Overall, it can be concluded that the aforementioned food additives can be used as safe additives at low concentration in food industry."	( Safety assessment of sodium acetate, sodium diacetate and potassium sorbate food additives. Dehghan, P; Ezzati Nazhad Dolatabadi, J; Mohammadi, A; Mohammadzadeh-Aghdash, H; Shanehbandi, D; Sohrabi, Y, 2018)	0.8

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Occurs in Manufacturing (143 Items)

Item	Process	Frequency
Meats and their products	core-ingredient	220
Meats	core-ingredient	217
Prepared meats	core-ingredient	188
Sausages	core-ingredient	89
Snacks	core-ingredient	75
Plant-based foods	core-ingredient	45
Plant-based foods and beverages	core-ingredient	45
Salty snacks	core-ingredient	37
Appetizers	core-ingredient	36
Cereals and potatoes	core-ingredient	34
Crisps	core-ingredient	34
Chips and fries	core-ingredient	34
Meals	core-ingredient	24
Potato crisps	core-ingredient	20
Poultries	core-ingredient	16
Condiments	core-ingredient	15
Baking decorations	core-ingredient	15
Cereals and their products	core-ingredient	14
Smoked sausages	core-ingredient	13
Turkeys	core-ingredient	12
Turkey and its products	core-ingredient	12
Turkey breasts	core-ingredient	11
Frozen foods	core-ingredient	10
Groceries	core-ingredient	10
Sauces	core-ingredient	10
Flavoured potato crisps	core-ingredient	8
Puffed rice cakes	core-ingredient	6
Puffed cereal cakes	core-ingredient	6
Corn chips	core-ingredient	5
Seafood	core-ingredient	5
Pastas	core-ingredient	3
Ketchup	core-ingredient	3
Tomato sauces	core-ingredient	3
Chicken and its products	core-ingredient	3
Peanuts	core-ingredient	3
Nuts	core-ingredient	3
Nuts and their products	core-ingredient	3
Legumes	core-ingredient	3
Legumes and their products	core-ingredient	3
Sweet snacks	core-ingredient	3
Frozen meats	core-ingredient	3
fr:Charcuteries diverses	core-ingredient	3
Soups	core-ingredient	2
Noodles	core-ingredient	2
Chips	core-ingredient	2
Hams	core-ingredient	2
Chickens	core-ingredient	2
Frozen seafood	core-ingredient	2
Crackers	core-ingredient	2
Meat preparations	core-ingredient	2
Confectioneries	core-ingredient	2
Salmons	core-ingredient	2
Fatty fishes	core-ingredient	2
Fishes	core-ingredient	2
Hummus	core-ingredient	2
Spices	core-ingredient	2
Pork Pâtés	core-ingredient	2
Pâté	core-ingredient	2
Beef	core-ingredient	2
Beef and its products	core-ingredient	2
Meat/Poultry/Other Animals Unprepared/Unprocessed	core-ingredient	2
Udon	core-ingredient	1
Salad dressings	core-ingredient	1
Chicken breasts	core-ingredient	1
Frozen poultry	core-ingredient	1
Ketchup crisps	core-ingredient	1
Barbecue crisps	core-ingredient	1
en:corn-chips	core-ingredient	1
Roasted peanuts	core-ingredient	1
Roasted nuts	core-ingredient	1
All dressed crackers	core-ingredient	1
Chicken sausages	core-ingredient	1
Poultry sausages	core-ingredient	1
Chicken preparations	core-ingredient	1
Frankfurter sausages	core-ingredient	1
German sausages	core-ingredient	1
Sunflower seeds and their products	core-ingredient	1
Chocolate candies	core-ingredient	1
Cocoa and its products	core-ingredient	1
Wild salmons	core-ingredient	1
Fishes and their products	core-ingredient	1
en:hams	core-ingredient	1
Wafer thin ham	core-ingredient	1
Coated peanuts	core-ingredient	1
Instant noodles	core-ingredient	1
Dried products to be rehydrated	core-ingredient	1
Dried products	core-ingredient	1
Dips	core-ingredient	1
Salted spreads	core-ingredient	1
Plant-based spreads	core-ingredient	1
Spreads	core-ingredient	1
Mixtures of herbs and spices	core-ingredient	1
Salads	core-ingredient	1
Prepared salads	core-ingredient	1
Fruits and vegetables based foods	core-ingredient	1
Pork liver Pâtés	core-ingredient	1
Liver Pâtés	core-ingredient	1
Charcuteries à cuire	core-ingredient	1
Allumettes de bacon	core-ingredient	1
Bacon fumé	core-ingredient	1
Bacon	core-ingredient	1
Porc	core-ingredient	1
Charcuteries diverses	core-ingredient	1
Porc et dérivés	core-ingredient	1
Frais	core-ingredient	1
Charcuteries	core-ingredient	1
Viandes	core-ingredient	1
Viandes et dérivés	core-ingredient	1
Salt and vinegar crisps	core-ingredient	1
Minced meat	core-ingredient	1
en:chickens	core-ingredient	1
Rye-and-wheat breads	core-ingredient	1
Breads	core-ingredient	1
en:white-hams	core-ingredient	1
Crisps made from reconstituted potato	core-ingredient	1
Beef preparations	core-ingredient	1
Crutons	core-ingredient	1
en:Snacks	core-ingredient	1
Salmon fillets	core-ingredient	1
Fish fillets	core-ingredient	1
Minced turkey ham	core-ingredient	1
fr:Allumettes de volaille	core-ingredient	1
Pancake	core-ingredient	1
Crêpe e galette	core-ingredient	1
Chicken seasoning	core-ingredient	1
Ostrich steak	core-ingredient	1
Puffed salty snacks made from maize	core-ingredient	1
Puffed salty snacks	core-ingredient	1
fr:Poitrines fumées	core-ingredient	1
fr:Charcuteries à cuire	core-ingredient	1
Pork belly	core-ingredient	1
Products without gluten	core-ingredient	1
Pork	core-ingredient	1
Products for specific diets	core-ingredient	1
Pork and its products	core-ingredient	1
Fresh foods	core-ingredient	1
Specific products	core-ingredient	1
Squid	core-ingredient	1
en:chocolate-cakes	core-ingredient	1
Chocolate Pound cake	core-ingredient	1
Pound Cake	core-ingredient	1
Cakes	core-ingredient	1
Biscuits and cakes	core-ingredient	1

Research

Studies (30)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	27 (90.00)	24.3611
2020's	3 (10.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 91.59

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	91.59 (24.57)
Research Supply Index	3.47 (2.92)
Research Growth Index	5.04 (4.65)
Search Engine Demand Index	162.12 (26.88)
Search Engine Supply Index	2.04 (0.95)

This Compound (91.59)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	31 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
acetic acid Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons.	2.77	3	monocarboxylic acid	antimicrobial food preservative; Daphnia magna metabolite; food acidity regulator; protic solvent
acetoin [no description available]	2.06	1	methyl ketone; secondary alpha-hydroxy ketone	metabolite
lactic acid Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.	2.48	2	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
histamine [no description available]	2.11	1	aralkylamino compound; imidazoles	human metabolite; mouse metabolite; neurotransmitter
hydroquinone [no description available]	2.6	1	benzenediol; hydroquinones	antioxidant; carcinogenic agent; cofactor; Escherichia coli metabolite; human xenobiotic metabolite; mouse metabolite; skin lightening agent
triphosphoric acid triphosphoric acid: used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative; RN given refers to parent cpd; structure	2.25	1	acyclic phosphorus acid anhydride; phosphorus oxoacid
potassium chloride Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.. potassium chloride : A metal chloride salt with a K(+) counterion.	2.1	1	inorganic chloride; inorganic potassium salt; potassium salt	fertilizer
sodium citrate, anhydrous Sodium Citrate: Sodium salts of citric acid that are used as buffers and food preservatives. They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.. sodium citrate : The trisodium salt of citric acid.	2.47	2	organic sodium salt	anticoagulant; flavouring agent
arginine Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group.	2.77	3	arginine; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	biomarker; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical
thymol Thymol: A phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent.. thymol : A phenol that is a natural monoterpene derivative of cymene.	2.15	1	monoterpenoid; phenols	volatile oil component
propylparaben Parabens: Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)	2.15	1	benzoate ester; paraben; phenols	antifungal agent; antimicrobial agent
butylparaben [no description available]	2.15	1	organic molecular entity
monolaurin monolaurin: RN given refers to cpd with unspecified monolaurin locant. 1-monolauroylglycerol : A 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group.. rac-1-monolauroylglycerol : A rac-1-monoacylglycerol comprising equal amounts of 1-lauroyl-sn-glycerol and 3-lauroyl-sn-glycerol	2.05	1	1-monoglyceride; dodecanoate ester; rac-1-monoacylglycerol
2-tert-butylhydroquinone 2-tert-butylhydroquinone: an anticarcinogenic and chemopreventive agent. 2-tert-butylhydroquinone : A member of the class of hydroquinones in which one of the ring hydrogens of hydroquinone is replaced by a tert-butyl group.	2.6	1	hydroquinones	food antioxidant
phenyl acetate phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.	4.76	28	benzenes; phenyl acetates
glucuronic acid Glucuronic Acid: A sugar acid formed by the oxidation of the C-6 carbon of GLUCOSE. In addition to being a key intermediate metabolite of the uronic acid pathway, glucuronic acid also plays a role in the detoxification of certain drugs and toxins by conjugating with them to form GLUCURONIDES.. D-glucuronic acid : The D-enantiomer of glucuronic acid.. D-glucopyranuronic acid : A D-glucuronic acid in cyclic pyranose form.	2.06	1	D-glucuronic acid	algal metabolite
n(alpha)-lauroylarginine ethyl ester N(alpha)-lauroylarginine ethyl ester: an antimicrobial surfactant; RN given refers to (L)-isomer	2.49	2
fibrin Fibrin: A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.	2.05	1	peptide
pectins Pectins: High molecular weight polysaccharides present in the cell walls of all plants. Pectins cement cell walls together. They are used as emulsifiers and stabilizers in the food industry. They have been tried for a variety of therapeutic uses including as antidiarrheals, where they are now generally considered ineffective, and in the treatment of hypercholesterolemia.. alpha-D-galacturonic acid : The alpha-anomer of D-galacturonic acid.	2.06	1	D-galactopyranuronic acid
sodium acetate, anhydrous Sodium Acetate: The trihydrate sodium salt of acetic acid, which is used as a source of sodium ions in solutions for dialysis and as a systemic and urinary alkalizer, diuretic, and expectorant.	2.79	3	organic sodium salt	NMR chemical shift reference compound
sorbic acid Sorbic Acid: Mold and yeast inhibitor. Used as a fungistatic agent for foods, especially cheeses.. (2E,4E)-hexa-2,4-dienoic acid : A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.. sorbic acid : A hexadienoic acid with double bonds at C-2 and C-4; it has four geometrical isomers, of which the trans,trans-form is naturally occurring.	3.03	4	alpha,beta-unsaturated monocarboxylic acid; sorbic acid
menaquinone 6 menaquinone 6: RN given refers to (all-E)-isomer	2.06	1
chlorophyll a Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.	2.15	1	chlorophyll; methyl ester	cofactor
chitosan [no description available]	2.1	1
sodium lactate Sodium Lactate: The sodium salt of racemic or inactive lactic acid. It is a hygroscopic agent used intravenously as a systemic and urinary alkalizer.. sodium lactate : An organic sodium salt having lactate as the counterion.	3.7	9	lactate salt; organic sodium salt	food acidity regulator; food preservative
sodium nitrite Sodium Nitrite: Nitrous acid sodium salt. Used in many industrial processes, in meat curing, coloring, and preserving, and as a reagent in ANALYTICAL CHEMISTRY TECHNIQUES. It is used therapeutically as an antidote in cyanide poisoning. The compound is toxic and mutagenic and will react in vivo with secondary or tertiary amines thereby producing highly carcinogenic nitrosamines.. sodium nitrite : An inorganic sodium salt having nitrite as the counterion. Used as a food preservative and antidote to cyanide poisoning.	2.08	1	inorganic sodium salt; nitrite salt	antidote to cyanide poisoning; antihypertensive agent; antimicrobial food preservative; food antioxidant; poison
brine brine: not from seawater; contains sodium chloride; calcium chloride; magnesium chloride; one or all of the above	2.06	1

Condition	Indicated	Relationship Strength	Studies	Trials
Food Poisoning [description not available]	0	2.07	1	0
Infections, Listeria [description not available]	0	2.07	1	0

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