Page last updated: 2024-10-15

darutoside

Description

darutoside: from Siegesbeckia glabrescens Mak; RN given refers to (2R-(2alpha,4aalpha,4bbeta,7alpha(R*),10abeta)) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID146159280
MeSH IDM0173893

Synonyms (2)

Synonym
darutoside
59219-65-7

Pharmacokinetics

ExcerptReference
" The present method was successfully applied to the pharmacokinetic study of kirenol in male Sprague-Dawley rats after oral administration at a dose of 50 mg/kg."( A rapid and simple RP-HPLC method for quantification of kirenol in rat plasma after oral administration and its application to pharmacokinetic study.
Fu, HZ; Qian, RQ; Song, XL; Wang, ZM; Zhang, QY, 2011
)

Dosage Studied

ExcerptReference
" Darutoside possesses the activity of termination of early pregnancy in experimental rats at a dosage of 20-40 mg/kg."( [Studies on antifertility constituents of Siegesbeckia glabrescens Mak].
Chen, M; Dong, XY; Huang, DX; Jin, W; Li, HT; Shen, SM, 1989
)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]