| Assay ID | Title | Year | Journal | Article |
|---|
| AID480349 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution assay in presence of 2% bovine serum albumin | 2010 | Journal of medicinal chemistry, May-27, Volume: 53, Issue:10
| Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties. |
| AID759009 | Inhibition of cell division in penicillin-susceptible Staphylococcus aureus ATCC 25923 at 2048 to 4096 ug/ml after 5 hrs by phase-contrast light microscopy analysis | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID392210 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 601055 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394542 | Antibacterial activity against Bacillus subtilis bearing FtsZ G196A mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID154621 | The compound was tested for poly(ADP-ribose)-polymerase (PARP) inhibition | 2001 | Journal of medicinal chemistry, Nov-08, Volume: 44, Issue:23
| Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis. |
| AID394540 | Antibacterial activity against Staphylococcus aureus bearing FtsZ G266S mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID392214 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700698 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394537 | Antibacterial activity against Staphylococcus aureus bearing FtsZ G196A mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID759018 | Antibacterial activity against penicillin-resistant Staphylococcus aureus clinical isolate after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID392219 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394539 | Antibacterial activity against Staphylococcus aureus bearing FtsZ N263K mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID759021 | Antibacterial activity against penicillin-susceptible Bacillus subtilis ATCC 9372 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID394519 | Antibacterial activity against Staphylococcus aureus by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID392212 | Antibacterial activity against Staphylococcus aureus ATCC 601055 with FtsZ P300R point mutation | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID759016 | Antibacterial activity against penicillin-susceptible Streptococcus pyogenes after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID392206 | Inhibition of FtsZ-mediated cell division in Bacillus subtilis 168 assessed as drug concentration required to produce filamentation | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394541 | Antibacterial activity against Bacillus subtilis bearing FtsZ A47P mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID480351 | Inhibition of Staphylococcus aureus ATCC 29213 FtsZ assessed as appearance of enlarged cells at 2048 to 4096 ug/mL by light microscopy | 2010 | Journal of medicinal chemistry, May-27, Volume: 53, Issue:10
| Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties. |
| AID394535 | Antibacterial activity against Staphylococcus aureus bearing FtsZ R191P mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID480348 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution assay | 2010 | Journal of medicinal chemistry, May-27, Volume: 53, Issue:10
| Creating an antibacterial with in vivo efficacy: synthesis and characterization of potent inhibitors of the bacterial cell division protein FtsZ with improved pharmaceutical properties. |
| AID392208 | Antibacterial activity against Staphylococcus aureus ATCC 29213 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID759023 | Inhibition of cell division in penicillin-susceptible Bacillus subtilis ATCC 9372 assessed as lowest concentration required to filamentation after 5 hrs by phase-contrast light microscopy analysis | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID759020 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 29213 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID392211 | Antibacterial activity against Staphylococcus aureus ATCC 601055 with FtsZ M2181 point mutation | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394538 | Antibacterial activity against Staphylococcus aureus bearing FtsZ V214F mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID392213 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 607004 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID392218 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 19636 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID759019 | Antibacterial activity against penicillin-susceptible Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID392205 | Antibacterial activity against Bacillus subtilis 168 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID392216 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 29213 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID392215 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394544 | Antibacterial activity against Bacillus subtilis bearing FtsZ V307H mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID394518 | Antibacterial activity against Bacillus subtilis by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID392217 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ. |
| AID394543 | Antibacterial activity against Bacillus subtilis bearing FtsZ V307R mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID394536 | Antibacterial activity against Staphylococcus aureus bearing FtsZ G193D mutant by broth microdilution method | 2008 | Science (New York, N.Y.), Sep-19, Volume: 321, Issue:5896
| An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. |
| AID759017 | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae ATCC 49619 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 23, Issue:14
| Synthesis and on-target antibacterial activity of novel 3-elongated arylalkoxybenzamide derivatives as inhibitors of the bacterial cell division protein FtsZ. |
| AID1811 | Experimentally measured binding affinity data derived from PDB | 1998 | Biochemistry, Mar-17, Volume: 37, Issue:11
| Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling. |
| AID977608 | Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB | 1998 | Biochemistry, Mar-17, Volume: 37, Issue:11
| Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID493017 | Wombat Data for BeliefDocking | 2001 | Journal of medicinal chemistry, Nov-08, Volume: 44, Issue:23
| Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |